Children's Hospital Of Eastern Ontario MASTER FORMULA SHEET NON-STERILE MANUFACTURING PRODUCT: CHOLESTYRAMINE 5% OINTMENT

Date Prepared: ____________ EXPIRY DATE: ____________ INGREDIENT Cholestyramine powder (sugar-free) Aquaphor ointment MANUFACTURER PMS LOT # MAN. EXPIRY DATE FORMULA QUANTITY 10 g 80 g QUANTITY USED MFG BY CHK BY FINAL PRODUCT CHECKED BY: _____________________

Beiersdorf

Sterile water

80 mL

EQUIPMENT Mortar and pestle Graduated cylinder Ointment pad Spatula

SAMPLE LABEL Cholestyramine 5% ointment Refrigerate. For external use only. Date Prepared: Date Expired: STABILITY 6 months in fridge. REFERENCE(S) White CM, Gailey RA, Lippe S. Cholestyramine ointment to treat buttocks rash and anal excoriation in an infant. Ann Pharmacother 1996;30: 954-6.

MANUFACTURING DIRECTIONS 1. Wear masks and gloves 2. Combine cholestyramine and water in mortar and pestle to yield an orange liquid. 3. Put Aquaphor ointment onto ointment pad, gradually add in cholestyramine liquid to combine. 4. Transfer into ointment pots. Refrigerate. FINAL APPEARANCE Smooth, pale orange colour. Master Sheet Revision Dates: 5Jan07 Final Approval By: CM/JH

**NOTE: CHOLESTYRAMINE POWDER 5 g = CHOLESTYRAMINE RESIN 4 g** **DONOT SUBSTITUTE WITH ANOTHER BRAND**

The non-sterile manufacturing formulas are provided for informational purposes for qualified health care professionals. The hospital will not assume responsibility for the continued currency of the information, any errors or omissions, and/or any consequences arising from the use of the information outside of CHEO.