Autoregulation

BLOOD PRESSURE Hypertension Preload Fluid Volume

= CARDIAC OUTPUT = Increased CO Contractility

x and/or

PERIPHERAL RESISTANCE Increaced PR Structural hypertrophy

Functional Constriction

Volume Redistribution Sympathetic nervous overDecreased activity filtration surface Stress

ReninAngiostensin Excess

Cell Membran Alteration

Hyper Insulinemia

Renal Sodium Retension

Obesity Genetic Alteration

Endothelium derived factors

Excess Genetic Sodium Alteration Intake

PUSING
HIPERTENSI

PENINGKATAN TAHANAN PERIFER

PENURUNAN SUPLAI OKSIGEN

KELELAHAN

 PENUMPUKAN GARAM

VOLUME CAIRAN EKSTRA SEL

BUANG AIR KECIL JARANG (KELUARAN URIN MENURUN)

PENUMPUKAN GARAM PENINGKATAN OSMOLARITAS CAIRAN H IPOTALAMUS MENSEKRESIKAN ADH KELUARAN URIN VOLUME CAIRAN

MINUM BANYAK
PENINGKATAN OSMOLARITAS CAIRAN

OSMOLARITAS CAIRAN MERANGSANG PUSAT HAUS DI OTAK GINJAL BERMASALAH VOLUME CAIRAN

 PENGLIHATAN KABUR NOKTURIA EDEMA