CUSHINGS SYNDROME

HORMON KORTISOL
Golongan glukokortikoid Zona fasikulata adrenal Fungsi :
mempertahankan tekanan darah dan fungsi jantung respon inflamasi system imun <<< mengatur metabolisme karbohidrat, protein, dan lemak merespon keadaan stress ***

CUSHINGS SYNDROME
Kadar hormon kortisol >>>> Jarang terjadi Epidemiologi :
Pada dewasa : 90% usia 20-50 tahun 10-15/1 juta Anak 2/10 juta/tahun

 Kortikosteroid >> dan lama Pseudo-cushing syndrome

DIAGNOSIS
Urin 24 jam Dexamethasone supression test CT SCAN, MRI

REFERENSI
Harvard Medical School. Cushings syndrome. 2012 (cited on 19 Sept 2013). Available at : http://pituitary.mgh.harvard.edu/cushings.htm Stewart PM, Krone NP. Williams Textbook of Endocrinology. 12th ed. Philadelphia : Saunders Elsevier ; 2011. Adler GK. Cushing Syndrome. 2013 (cied on 19 Sept 2013). Available at : http://emedicine.medscape.com/article/117365overview#aw2aab6b2b3aa National Institute of Diabetes and Digestive and Kidney Diseases. Cushings syndrome. 2012 (cited on 19 Sept 2013). Available at : http://endocrine.niddk.nih.gov/pubs/cushings/cushings. aspx