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.
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#3 .
.
() .
, , , (, , , ,
, , , , , ) ,

, .
,

. 855
52.67% 95.58%.
3 .
102 T 27.34 +- 7.8%
49.75 +- 7.5% .
. (p < 0.001)
SK-SD ,PHA

. 25
IgA,IgG . (P < 0.05)
: 40g, 18g, 20g, 150g, 40g,
18g, 24g, 40g ()
10 .
3, 4 .
3.

. 1974

.
.
#1 .
#2
( ).
#3
.
#4
.

,
.
,

. (P < 0.01) IgG, IgA, IgM
IgM , ,
. cAMP , cAMP/cGMP
cGMP (P < 0.05)
. cAMP
.

( 6, 6, 25)
37 (29) (8)
. 24 . cAMP
76.65, 132.26, 67.25
. (P < 0.001) cAMP

 . (P < 0.01)
, E-
(P < 0.01).
. IgA
.
.
. cAMP
.
cAMP ,
. cAMP cAMP/cGMP
. cGMP cAMP/cGMP
.
(1:100 ) 3 cGMP
26.9 .
. (1:5) cGMP
. .
.

.
. (, , )
(,.) .
, , , ,
.
,
, (, , , , )
.
. ,
1
260 190mg% . B- 920
375mg% triglyceride 670 129mg%
. 6
.
, , Ts
.

. .

.
.
.

.
T .

,
.
.
, .
, ,
. , , , ,
.

.

,
.

.
.



. 3-4 .
.
.
T
.


, .
.
.

. Dressler 1956 10, 1959
32 2-11 , ,


(PMIS) . 80%
.

.

.
2

. 2 (, , , , )
.
.
Ts
.
4.
5%
.
95%
.
. B
.

.

.

.
.
. ,
.
", , , , , , ,
" 79 98.7% .
4 (, , , , , 10g,
, , 15g) 120 , 86
24 91.7% . ,
. 120g
.
.

.
.
, ()
.


.

.
.
100 , 82% ,
, 15 , 6 ,
7 .


.
,
64 93.4% .
, , cAMP , ,
.
.

(, , ) 50
94%.
.
.
, , ,
.
B T .

.

.
. ?
() () .
( ) T (
) . T, Ts Th
.
,
.
() : 95%
, ( 10ml 6.25g,
1.25g) . ml 0.5g .
10-15ml 1 3 1 .
1 20-25ml . 2
2
.
5.
80%
LAST IgG
.
70

IgG
, P < 0.01 .
, ,
, , , .
, (, , , ,
, , , ) 37
83.5% .

, , ,
, , , , , , 56
96.4% .

 3
, , .
, , , , , ,
33 97% .

26 92.2% .
1 ( ) 27
92.0% .
, ,
.

.
(, , , , ,
, ) Ts cAMP
(P < 0.05),
.
cAMP
.
() cAMP cGMP
, cAMP/cGMP .
cAMP/cGMP
.
.

( ).
.
.
6.
30%,
.
. A, B AB 3
. A ,
,
.
B
. AB ,
. B
.
1980 ,
.
B
.
1981 (
1) (, , , ) 118
116 80% .
1982 ,
.
1981 (), () 140 . ()
, , , , , , C ,
() , , , , , ,
. . 3
.
() 50 5, 35, 10.
45 5 ,
34 , 6.
() 60 19 37 ,
4. 85.7%. 50 1
34 , 5. 100
10 ()

 , .
, , , .
,

.
7. B
.
2 ,
.
.
35
7 90% .
.
60 31
(51.6%), 15 (25%).

.
,
.
, , 52
40 (76%).

(P < 0.001)
. B 103 HBsAg
54.4%.
HBsAg ,
, , , , , ,
. .
HBsAg
.


.
. , ,
(, , , , , , , ,
, , , , , , , ) 35 33
(94.3%) , 74.4 .
25 18 (72.3%)
120.6 . ,
. () .
(1981)
. T B

.

.
.
(1981) 52
(, , , , ,
)
.
(1981) 101 70%
T . , ,
, , , , ,
, , 51.48%
.

. ()
.

 ()
. HBsAg , GPT
GPT HBsAg
. , .
.
80 ,
, , 4 .
, IgM HBsAg
.

HBsAg .
, IgM
.
, , , 70 LSP ()

6 .
90% 7.14% .

.
.
(HBsAg LSP )
. ,
.


. .
8.
75% (lgG) . lgG
IgG
.
, ,
, , , , ,
.
.
110
89.54%,
98.48% .
1982
. , ,
. ,
, . (, ,
, , , , , , , , , , ,
, , , , , ) .
,
, .
1981 (T2) 30
1-3 . 1,
17, 12, 100%.
, .
T2 T
.
,
. B

.
1981
cGMP .
12 4
, , , .

9.

.
DNA - (LE)
.
.
(1974) , , , , , ,
, , , , , , , , , , ,
100 80%
.
1977 1980 ,
. 1977

, ,
, , . ,
, , 4 .
, , , ,
6 .
1980
.
,

.

.
, , , .
.
107 80 (84%).
1981 111

. , , ,
4 . 26 49,
10 26 .
.
.
1981 50
30 15, 5. 8
3
. .
DNA
. arteannuin
.
1882
26 .1 1
2-6 8 10 6 ,
2 92.3% .
.
10.
() ()
'' () . ,
, ,
. , ,
, .
, , , , ,
, , , , , , , 100
36 10
. 3 9
1 8, 83, 4,

5.
1978 1 ,
,
. 1
.
.
(1981) 335 248
87 . 6
. , , , ,
. ( )
68.7% . 64.7%
94.2% .
102

.
.

.
.

, ,
.
11.

.
, - 73.0%
.
.
.
2 50 (
) ,
, , ,
(, , , , , , ) 43.4
. , (, ,
, , , , , , , , , , )
2 2 , ,
50g 3 . 3
, ,
.
, .
, , , , .
, , , ,
, . .
1 . 9
.
, , , , ,
, 9 .
.
,
, ,
.
,
.
.
.

.
12.

 1937 .
, .
''
.
,
3 , , 3
. 4
.

, ,

.
276
,
-
lgDa (2)
.

.
.
.
.
.
5

. , , .
, , , .
.
(, , , , , )
. ,
.
.
, 2g 1 3
(3 ) .
.
. .

. .
7 3 4 ,
25 9 11 5
. .


. 1 15 10

,
.
. 6
. 6 .

.

.,
.
13.
.
500 200 .
.

 .
.
R.A.Gatt
.
100 .
.
.
T
.
.
.
(), ()
.

.
48 84.5%
93.75% 39.58%
.
S 4
108 1
39 . 18
3 . , ,
200 51.5% 1
74 37% 9 .

T
. P 37
, 2 (, , , , , ,
) .
6 (, , , , ,
) 21
16 .
1 (, , , , , , ) 2
(, , , , , )
. 2 18
1 5 .
S (, , , , ) 14
2 37.3% 56.9% (P <
0.01) . (, , , , )
(, , , , , ) 41
3-6
43.6% +- 1.85% 56.7 +- 5.7% (P < 0.001)
. 31
1 38.2 +- 5.3% 58.0 +- 3.7% (P < 0.001)
, 0.5 +- 0.008 0.95 +- 0.11 (P
< 0.01) , 2 3
.
572
465 107 . ,
, , , 2
. .
.
. .
.
.
, .
, camptothecine 53
46.colchicine colchamine
74%
.

 16 6 2 8
.


T , ,
.
.
14.
.
.
,
.

.

.

.
. 1974
, , , ,
54 .
1979
.
.
, , , , ,
, , . ,
.
9
2 5
3 1 1 3
.
(1982)
imuran prednisone
, , , , , , , ,
, , , , , , , , .

.
. , .

.

.
15.
.

.
.
.

. -> ->
.
.
.
.
-> ->
, , , , . ''
() (, , ), (, , , ,
, ), (, , , ), (, ,

), (, , , ), (, , , ,
, ) , ,
.

.
.
.
.
?
.
.
.
.
.
37 T
25.56% +- 6.3% 20
T 52.6 +- 2.5% 2
. (P < 0.01). 3
T .
T . T
,
() ,
. T B
. B

. T . T
. T
.
.

.
.
.
.
T
, T
.
.
( -> -> ) .

.
, ,
.
.
,
. .
60 (25), T (32,80 +- 6.02%)
20-30 (20) (52.68 +- 2.47%), SK-SD (3.45%)
30 (53.38%) , PHA (2.10
+- 1.04mm) (8.36 +- 2.7mm)
. ,
.
.
T
(
) .
. .
'' (, ) .
. '' () (, ,
), (: ) ,

.
.

.

.
.
( -> -> ) ( -> -> ) .
( -> ->
)
.

. ,
. (, )
, . ,
,
.
.
'' , ,
.
98 (, ,
)
. 101
40 , 50
.
.

.
. 1959 '', '' 20
160 .
. , ,
, , , , , , ''
, ,'' , ''
.
, , , , ,
, , , , , , , , , , , ,
, .


.
. , , , , , ,
, T , T
.

61 88-89 . T
T
. T
.

.
.
.
(, , , , ) .
, , ,
300 .
.
.
.
(, , )

 . 60

. 90
.
. 45-89 25 11
.
.

. , .
.
.
. ,
, ,
.

.
.
'' (, )
. (, )
.
. , , T
.

.
.
.
, , ,
.

.
@ff
2

, , ,
. ,
. , ,
, , , , .
,

. , ,
.
, ,
, .
, , ,
.
, ,
, , , , ,
, ,
, (SLE), , ,
, .
, , ,


, , , ,
, , , , , , ,
.
, , , ,
.
'' ( ), ( ) .

 .

.
.


.
,
, .

. ( )
. (
) . ,
.
.
.
.
( )
() ,
.
, , .
'' ( ), ( ), (
) . ''

. ( .
.
? .)

.
.
, .
, .
( () )
. ( )
.
- .
- , .

- .

.
,
. , .
, ,
( , , )
.
.
, (
), ( ) .
.
, ( ), (
)
. .
, ,
. '' ()
. ( , ,
.
.
. ,
.) , (

 ) (-).

, A (SIgA) ,
.
,
. ,
. , , ,
, , , .
, ...
. ,
. ,

.
.
, cAMP, cGMP
(cAMP/cGMP) .
cAMP .
, ,
.
,
.
@ff
1
1.
, Astragalus membranaceus (Fisch.) Bunge, A.
mongholicus Bunge . ,
.
(1)
, -sitosterol, linolic acid, linolenic acid.
:
(I) 7, 3-dihydroxy-4-methoxyisoblavone
(II) (3R)-2, 3-dihydroxy-7, 4dimethoxyisoblavone
(III) (6aR, 11aR)-10-hydroxy-3, 9-dimethoxypterocarpan .
:D-glucose, D-fructose, sucrose.
.
, , .
(2)
, .
(3)
. ,
, . '' (
...
.
. ...
. ) . '' (
.
) .
(4)
#1
0.3ml 5
(P < 0.01).
, .
#2

.
, ()

 .
. () ,
.
,
,
8-12 .
, .
,
. ()
.
.
22 ,
. ,
. ,
,
.
.
.
'' (
) . '' (
) .


.
.
#3
I 1898 28 ,

(P < 0.001).
10-14 , ()
, 107 ,
2.0, 50% .
. ,

. ().
NDV ( )
.
.
.
(P <
0.01) .
NDV
. ,
.
.
3H-
(P < 0.01). RNA
.

. cAMP (),
cMAP .
,
.
. '' (
) ,
.
.
#4 cAMP CGMP
cAMP
, .

 cAMP ) cAMP .
cGMP cGMP
. (, , ) cAMP, cGMP
cAMP/cGMP . ,
. (
) . cAMP
, cAMP
. cAMP
.
#5
, T,
B .
IgS 7S
. () cAMP
cAMP/cGMP , CGMP
.

. ,

.
.
.
cAMP .
16g, 20 IgM (P <
0.05), IgE (P < 0.05) cAMP .
. .
.
. 40 IgG
.
83 20 IgG, IgA, IgM
(P < 0.01-0.001),
SIgA
(P < 0.01).
IgA/IgG IgA IgA/IgG
.
SIgA (P < 0.001).
.
SIgA
. ( )
.
#6

. (LPS) .
, ,
. B (HBsAg)
.
#7
, (goldenhamster; )
, .
61 88-99
.
( )
, (
) .
,
. 3 , BB, 3 ,
, NDV

.
.

 .
.
.
#8
. ,
.
.

.

.

.
(5)
#1 .
55 2ml 7-17 1000/mml
61.2% .
#2
'' ( ) .
, (
). ,
, 41
. 2, 3 1 3-4 .
2 . ,
56.1%, 29.3% 85.4%.
( .
, . ,
IgG IgA ,
.
. (
) . 51
26 IgA, IgG
EAC .
.
#3

.
24
17,
6 . 18 17 , 19
. .
, CH50, C3, PFC, IgG, IgA ,
IgM . ,
.
#4
2, 2ml 50 .
3-6 11, 35.
#5 B
B (HBsAg) 84
4ml 2 , 51.5%,
78.9%. HBsAg 26.1%, 23.2%.
33 22
.
.
. .
B
, T (Ts)
. , Ts B
B

.
Ts
.
#6
, 9 5
. 398 .
(P < 0.05-0.01),
.
.
.
SIgA
. '' (
) .
, ( ), ... ,
.
(6)
#1 10-15g, 30-60g.
#2 . 2-4ml, 1 1-3, .
(7)
.
2.
Panax ginseng C.A.Mey,
.
(1)
: ginsenoside-Ro, Ra, Rb1, Rb2, Rb3, Rc, Rd, Re, Rf, Rg1, Rg2, Rh,
20-gluoginsenoside-Rf.
:panaxynol, -elemene.
: -sitosterol, -sitosterol glucoside.
: D-glucose, D-fructose, sucrose, maltose, trisaccharide A, B, C
: , , (choline), B, ATP, arginine.
, (, , , , , , , ),
.
(2)
. , .
(3)

. '' ( , ...

) . '' (
) .
(4)
4, 50
, .
#1
( ) .
, .
- ,

.
- .
-
.
-

 .
-
.
-
.
-
.
, , ,
, , , , , ,
, , , , , , , ,
.

.
. ,
,
, -
.
#2 -
- , .
- dextran
, .
- C
,
C ,
.
- (ACTH),
cAMP ,
. ,
ACTH .
- cAMP .
ACTH .

cAMP .

, ACTH
AMP ,
.
- .
- , ,
.
#3

, ,
. .
.
. ,
. ''
" ( ) .
( .)
#4
, ,
. ,
.
.
,
. ( ...
) . . ( ,
.
). furuncle,
.

#5
(LPS)
.
Rg1 in vitro .

0.0003-0.0005mg/ml. 12
(Go) .
spira , IgG
. .
#6 ,
prostisol ( Rb1, Rb2, Rc, Rg1 )
in vivo, (DNA),
(RNA), , . ,
RNA RNA ,
, ( )
. , , , , DNA
DNA
. RNA . RNA
Rb1, Rb2,
Rc.
#7
,

. . GNS
( Rb1, Rb2, Rc) , , , 5 -
.
.
, . ,

, .
.
, , ,

.
.
. .
,

. '' . (
,
35

. ).

.
(5)
#1 ,
, , ,
. , , ,
.
#2 , ,
, .
#3 , , ,
, , , .
#4 ( ) ,
DNA , DNA .
,

.

#5 , .
#6 .
.
(6)
#1 3-9g.
#2 : 1-2g, 2-3.
.
#3 : 1g/ml. 1-2ml, 2-3.
, , .
(7)
.
, ,
.
.
.
(8)
, , , , , , .
3.
Codonopsis pilosuld (Fr.) Nannf.,
.
. C.tangshen Oliv. .
(1)
inulin , , , , , , B1, B2,
.
(2)
. , .
(3)
. '', (

. ,
, ,

) .
(4)
#1
, ,
. , .
.
#2
5
.
,
. , .
.
.
. ,
.
() .
#3
,
.
,

 . (, , , )
C .
,
.
.
.
#4 cAMP
, cAMP ,
cAMP . cAMP
.
#5
( 50g, 20g, 125g) ,
(T ) 31.1 +- 5.9% 43.3 +8.7% (P < 0.01), 46.8 +- 12.9% 55.8
+- 12.1% (P < 0.01), IgG 173 +- 48.6mg 213 +- 66.4mg
(P < 0.05) , IgM, IgA .
,
.
.
(5)
#1
15 2 10 .
#2
15g, , , 9g, , 30g ,
30 ,
28.
, .
#3
14, 3-6
, 12, 2.
,
. , IgA, IgM
, EAC , cAMP
cGMP .
, , .
(, , , , ,
, , , , , , , ),
. ,
. ,
, .
.
(6)
10-15g, 20-50g .
(7)
, , .
4.
Atractylodes macrocephala Koidz.
.
(1)
, atractylon, atractylenolide I, II,
III .
A .
(2)
. , .

(3)
. ''
( ) . '' (

, ) .
(4)
#1 .
.
, .
#2
, C
. (
). .
#3
( ).
#4
180,
. ,
.

.
2-4 30-90% 2*106
. .
,
.
#5

, .
(GOT, GPT) ,
. .
(5)
#1 17
2, 8.
#2 ( ) , , ,
. ,
.
#3 .
, , ''
(, , , , ) . () .
#4 .
(6)
6-15g, .
(7)
, , , , , , , ,
, , , , , ,
, , , , , .
5.
Ganodermalucidum (Leyss. exFr.)Karst,
G.japonicum (Fr.)Lloyd, G.capense (Lloyd) Teng, G. sp. ()
. 2 .
(1)
, , , (r- ), ,
, , .

(2)
. ''
( ), (
), ( ) .
(3)
#1 .

.
#2

. (, , )
. .
.
.
.
#3
.
, ,
17- , ,
. .
#4
( )
.
.
, I II,
SRS-A , ,
SRS-A . G.sp.
. G.sp. ,
,
.

.
#5
. 20
SIgA (P < 0.001).
` ( ), (T) .
.
.
.
#6
- 20 .
2 ,
.
.
- , GPT
, .
. ,
,
.
- D6 .
. ,
,
.
, , , ,
. ( ) ( )
.
(4)

#1
660 , 500/mm
81.7% . 3917/mm 5345/mm
. 52 , 84.6%.
12 ,
3266/mm 5271/mm .
.
#2 ,
, 80-95%.
.
13 ,
. 5, 7,
1. . SIgA ,
. 4
(P < 0.001),

.
#3

.
#4 , , (SLE),
.
#5 18 , 16, 2.
. .
(5)
: 3-10g.
: 1 () 1g 2-3 3.
: 3-5ml, 3.
: 2-4ml, 2, .

#1
#2
#3
#4

(6)
80%
20-30 , ,
, , , , , , .
.
6.
(, , )Coriolus versicolor (Lr.) Quel
(Polystictus versicolor (L.Fr.) .
(1)
, , .
(2)
. , .
(3)
#1
- 180
.
- .
- .
- ( )
. (PHA)
(P < 0.01), (P < 0.01),
, .
, IgM IgG .
, ,
, (PHA) , .

 ATSO ( )
.
.
, 100mg/kg , C,
5- . ,
.
,
, B Ig .
PS-K ( )
.
, ,
. .
#2
, ATSO, PS - K
.
180
21 . 2 ,
90%
.
ATSO 180,
. PMS (
) , .
#3
ATSO C3
, 2
C3 2-3 . C3
.
#4
ATSO PR8 .
A2/Kumamoto (LD50) 3
ATSO . (HVJ)
.
ATSO .
.
.
.
.
#5
.
(4)
#1 , , , ,
, , ,
.
100
.
24 ( ( ) 8,
( ) 4, ( ) 3, ( ) 6,
3) 8,
5, 1, 2, 281
10 ( 6,
1, 1, 2) 5, 3,
2, 48 .
PS-K 289 , 25%
21.5%, 65.9% .
#2
529 , 20 39.1%,
82.8%, , .
124 48.4%, 31.5%, 87.1%.
#3

 , , , 2-6
50%,66-80%.
HBsAg 68
26 38.2% .
#4
100 (AFP)
,2-8 64, 1 55/79
(69.6%) 85% 1 .1 , 79
2 . 15 7,
8. 36 , 70
, IgA, IgG
(P < 0.05-0.01). , , (SLE),
.
(5)
#1 . 20-40g. .
#2 . 40mg. , 1, 2,
4 2 , 4 .
3-4 10% 30ml 1,10 7-10
10 1 .
#3 () , 0.5g, 1 3. 3.
#4 PS-K 1-2g, 3.
7.
Polyporus umbellatus (Pers.) Fr. .
(1)
( ), , , .
2-hydroxytertracosanic acid.
(2)
. , , .
(3)
, '' ( ...
) .
(4)
#1 . ( (757))
180 ,
. (5-)
,
(757) . ,
, .
1 .

.
.
#2
(757) 10 T
(P < 0.001), 1-2 T
(P < 0.05). ( )
(757) T
. T
.
#3
(757) 20, 25 ( 14)
,
.
#4

(757)
( ),
, 1
.
#5
(757) . ,

. - . (757)
. , (MTX)
.
'' () . ,
. ,
, ,
.
#6
(Glucan) 180 ,
8 6 35
. 42, 7432
. (757) 180
, 6-7% .
.
. (757)
. , cAMP
. (757) 180 cAMP .
cAMP .
cAMP .
cAMP , cAMP .
cAMP .
3H - RNA cAMP .
(5)
, , , ,
. ,
(757) , 300
, .
(757),
. (757) ,
.
(6)
#1 . 10-20g.
#2 (757) . 40mg, 1-2, .
(7)
.
8.
Lenronus edodes (Berk.) Sing. .
(1)
(Lentinane) . , (1 -> 6) (1 -> 3) (1 -> 3)
, , , .
(2)
. , .
(3)
.
(4)

#1
,
98% .
6.4% .
. 180
, .
. 7
, 180 1:8
, 180 5
59.7% .
180 37
23 .
, ( ),
.
,
. , CBA/J
, IgG2a 34.8,
IgG2b 94.7, IgG1 7.6 .
T ,
. , (BA)
DNP ,
BA CNP
T .

,
. .
.
C3 .
30
.
#2
180 10 6
. 14, -> .
, 5-
.
.
(5)
#1 ,
,
. ,
, .
#2 , , ,
.
.
.
(6)
10-30g, .
9.
Glycyrrhiza urakensis Fisch
.
(1)
glabric acid, gabrolide acid, 28 - hydroxyglycyrrhetic acid ().
: liquiritigenin, isoliqiuritin, isoliguiritigenin.
: 2 - methy - 7 - hydroxyisofkavone.
: licoricidin
: glycyrol, isoglycyrol.

 , (glucose, sucrose, mannitol).

: R = 2.
: R = H.
().
: putrescin.
(2)
. , , .
(3)
.
. .
. '' ()
)
. '' ( ,

) . '' (
) .
(4)
#1
, C
. -
. ,
. ,
.
, (ACTH)
. ,
( ,
).
.
,
. ,
,
. ,
ACTH , ,
, ,
.
. .
,
, , ,
, . (
) .
.
.
1958, C3
50% , 80%
. .
.
1 1978
C4; C5 C3
C17, C21 , C20
. 5-
, 5- .
, , , (
, ) - .

.
#2

. - (BA)
, Lx.
Lx BA
.

.
.
.
,
,
. LH T
.
#3
300 1 (g/ml)
,
. (, ())
.
#4
, , BCG
.
, ,
.
,
, .
#5
, , FM100 ( )
(
).

. FM100 , ,
.

cAMP ,
. ,
, , . FM100
.
,
.

.
,
.
#6 cAMP
cAMP
, .
cAMP cAMP
.
#7
.
,

. . ,

. .
,
,
GOT, GPT .
.
,
( ). ( )

 .
, , , ,
. .
, , .
(5)
#1
Rh ,
13 (A 8, B 2, Rh-D 2, Rh-C,
E, e 1) 7 A, 2 B
. , .
.
#2
30g
. 5 , 6.2 2-3
. 2
, , .
#3
5g 10ml 3, 3
. 1-3 .
4 .
, , ,
. ( ) ()
.
#4
11 . ,

.
. .
#5
2% 1-2 1 15-20
12 1-4 .
. ,
. , , ,
.
#6
, .
, (, ), (, ,
) .
, , , , (SLE),
.
95 ,
88.1% .
.
. .
, ,
.
(6)
#1 : 3-10g.
#2 : 10-15ml, 3.
#3 5% : .
(7)
. , , ,
.
(8)
, , , , , ,
, , , , ,

, , , , , , , ,
.
10.
() Dioscorea opposita Thumb,
.
(1)
.
: glucose, fructose, scurose.
(mucin), glucosamine, tyrosine, leuisine, glutamic acid, globuline, 3.4 dehydroxy-phenylalanine, chlor-ogenic acid, arginine, choline,alantoine, mannan,
diastase.
(2)
. , , .
(3)
, '' (
) .
(4)
#1

( ).
( ) ( ) .
.
#2
,

.
(5)

10, 4, 2 220
75.9%, 16.4%. ''
( ) .
, , , , ,
.
, , .
(6)
10-30g, .
(7)
, , .
11.
Coix lachryma-jobi L., .
(1)
, , , , .
: -sitosterol.
: coixenolide.
, phytin, Vitamin B1, , , .
(2)
. , , .
(3)

 .
'' ( .
) .
(4)
#1

.
#2

,
, 6
. '' (
) .
. ,
.
.
#3
, 180, , HeLa

. .
.
(5)
#1
,
, ( ). '',
'' . '' (,
, , ) (, , , )
. '' ( .
, ) , ( )
. ( ) ('') ,
, , . (''). ,
. 65 , 30-60g ( ),
10-20 51, 9.
12 , 11 . ,
, .
(, )
.
#2
, . , , ,
.
, .
(6)
10-30g, .
(7)
, .
12.
Ziziphus jujuba Mill. var. inermis (Bge.) Rehd.
.
(1)
: aleanolic acid, betulinic acid, alphitolic acid p-coumaric acid
, ursolic acid .
: zizyphus saponin .
: , , malic acid, tartaric acid, cAMP, cGMP .
, , .

(2)
. , , .
(3)
. '' (
12 ) .
( ,
). '' () .
(4)
#1 cAMP
cAMP
cAMP . cAMP/cGMP .
. , ,
, cAMP 10-15
, .
cAMP/cGMP ,
. cAMP

.
#2
IgE
, 100mg 5-10mg .
#3
3
.
. ,
.
(5)
#1
,
1 .
( )
, .
#2
30g, 7, 8 , 6
.
#3
'' , ( 12 ,
150g
. ) .

. , .
#4 ,
(, , 30g) 12
. , , ,
, .
(6)
10-30g, .
(7)
, , , , ,
, , , , , ,
, , .
13.
Phaeolus vulgaris L. , .

(1)
(PHA) . , , ,
.
(2)
. , .
(3)
#1
PHA . , PHA
, cAMP ,
.
,
.
. BSA
. IgG
IgM ,
. ,
.
PHA .

. , ,
.
PHA . MIF ( )
. ,
.
.
#2
PHA .
,
.
: PHA 2 2
.
5-10 ,
.
, .
.
(4)
#1
1978, PHA 403
. , 80 53 66.3% (
32 43.7%) , 21 15.
40 PPF (PHA, , 5-) 97.5%,
50% ( 16 93.7%, 31.2%.
8 4, 2. (, ) 52
31 59.6% .
#2
.
PHA ( )
50 , 84%. 20 50%,
. PHA 50 ( 15,
32, 3) 68% 15 .
, ,
. .
.
(5)
PHA 1 10mg .

#1
PHA 20-40mg 5% , 50%
() .
5-10 ,
5-10 . 2-3 .
#2
10-20mg, .
#3
0.1ml 10-20ug .
@ff
2
1.
Angelivca sinensis (Oliv)Diels,
.
(1)
, , , ligustilide, n - butylidenphthalide,
n - valer - ophenone - o - car - bonic acid, sedanonic acid, safrol, isosafrol,
p-cymene . Palmitic acid, linolic acid, stearic acid,
arachidonic acid, bergaptene, scopoletin, umbelliferone,
falcarinol, falcarindiol, falcarinolone ,
n-dodecanol, -sitosterol, -sitosterol glucoside, glucose, fructose,
sucrose, vanilic acid, nicotic acid, nicotinamide, pantothenic acid, falic acid,
folinic acid, vitamin B12, biotin .
(2)
. , , .
(3)
''
( )
'' ( ,
) .
(4)
#1 , .
,

.
( ), ( : '')
.
#2
.
(LPS) 2.
#3
.

.
(DNFB)
, DNFB
.
100mg/kg/, 5-10mg/kg/ .
, , , , , , (II)
,
. .
#4 (GVH )
, ( I)
, 4 3-9 ,
.
, 4 ,

 , .
#5
- 0.05%
.
, ,
.
- . .
-
.
- , ,
.
, ,
5- ,
.
(5)
#1
I ( 10g, 6g) 4
3 .
.
#2
'' " " ( )
. .
100ml, 1 3 , 20
, 18, 2. 2-10
0.5-2 .
(4-7), (5, 6 ) 9.4
88 , 85 96.6% .
#3
- (, , ). 2,
0.1-0.2ml. 1, 10-20 , , ,
147 , 70 47.6%, 40 27.2%,
31 21%, 6 4.1%. 75 ,
8, 27, 29, 11 85.4%.
- , , 350 ,
53 15.2%, 116 33.1%, 126 36%,
84.3%. '' , .
. (
). '' ( ) ,
'' ( ) .
.
#4
'' ( ) ,
'', ( ,
) .
(), () , ,
166 , 1-12
19, 37, 95 94.4%,
50.6%, 1 46.5%.
#5
2ml 5 ,
2. 30-120 .
#6
,
131
, 96 73.7%, 93.3%
.
#7 ,
(ZTT) .
PT .

#8
2 1.
#9
, ,
, 120 , 10 73 60.8%, 45
37.5%, 2 1.7%.
#10
, . ''
(, , , , ) , ''
(, , , ) ,
'' ( )
,
( ) .
.
(6)
#1 : 5-10g
#2 5% 10%
2-4ml . 1-3 ,
8-10ml .
(7)
, , , , , , , ,
, , , , , , , ,
, , , , , , , ,
, , , , , ,
, , , , , , .
2.
Polygonum multiflorum Thunb.,
.
(1)
, (, , ), , ,
, .
(2)
. , , , .
(3)
. ''
(
) . '' ( ) .
(4)
#1
-
(LPS) .
- ,
A (SIgA) . (P < 0.01),
.
( ) .
#2
-
.
- 31 ,
14 5C 17.5 , 32.3%,
67.7% .
.
, , ,

.
(5)
#1 ,
.
. , , .
#2

(P < 0.01),
, , , .
#3
.
, '' (, , , , ) .
'' (, , ) . ,
18-24g 2-3g 2 17 15
2 4 . 2 4
.
2-7 .
#4
78 .
, , , , .
(6)
10-20g, .
(7)
, .
3.
() .
3 (, ).
(1)
, , , - , ,
, ( , , ), ,
( 8), , (lipise),
xanthne, adenine, histidine, chorine, lysine, uracil, alanine, leucine, proline
,
glutamic acid, hypoxanthine, phenylalanine, glycigen, lecithin cholesterin
follriculin, phosphatide acetylcholine, oxytryptamine, histamine , oxyocin
, A.D.E. Ca.P.Fe (placentoglobulin).
(2)
. , , .
(3)
. '' (
) .
(4)
#1


.
. ,

.
#2

. 72.7%

 8.3% . .
.

.
#3
, (
).
, , 13
(LPS) .
,
.

. ,
.
, .
#4
86 , IgA
126.6mg/ml 171.6mg/ml . IgA
.
#5
,
.
#6
.
, ,
.
, , , , , , ,

.
(5)
#1
,
55 , , 65.5%.
27 , 63%.
17 , 9 , 8
.
#2
6 , 5.9 +1.0/mm 7.5 +- 1.7/mm . 10
, 5.0 +- 1.4/mm 9.8 +5/mm .
#3 ,
, 709, 210
( 6 ), 80%-90%,
,
, .
19 , 17 2 .
, ( )
83 ,
cAMP (P < 0.01).
#4
- 400 . 214
, 153 71.5% .
126 (0.5-5), 119 92,2% .
33 ( 38.5C-40.0C), 4-12
25.
- - ,
.

. ,
( : '')
.
, , .
(6)
#1 (): 2-6g.
#2 : 0.5-1mg, 1, .
#3 : 1 3ml, 6-9ml, 1-2 .
4.
Polygonatum sibiricum Redoute ,
.
(1)
, , , .
(2)
. , , .
(3)
. . '', (
, ) . '', (

) . '' (
) .
(4)
#1
,
, .
, 7 . ,
EAC
.
#2
, ,
. ,
.
.
.
(5)
#1
2, 1 100% 20ml , 3, 42
2 66.6%. (B4, , ...)
34 . 6
. ( )
.
,
( ).
#2
19 , 2
4, 12, 3. , , ,
.
(6)
10-15g, . .
5.
Equus asinus L.

 . , Succrofa
domestica Brisson .
.
(1)
, , ,
, , , . , , ,
, , , , , , , , ,
. , , ,
.
(2)
. , , .
(3)
. ''
( .) . (
) .
(4)
#1 T

.
#2
, , .
#3
-
.
- .
.
, .
'', (
.) , , ,
.
(5)
#1
30g 2, 10 , 24
6, 4.
#2
,
20 , 37%, 14.6%, 59.2%.
20 12.0%, 8.9%, 79.1%.
.
#3
2, 30g 24 ,
20 , 14, 6.
10 . ,
30g, 0.3g, 2 ,
11 (5 , 6 )
, 10 1 . ''

,
.
, , , ,
.
, , , , . ,
.
1400
1976 .

(6)
3-9g, .
(7)
, , , , .
6.
Millettia dielsiana Harms, M.retculata Benth.
Spatholobus suberectus Dunn , .
(1)
, , .
(2)
. , , .
(3)
.
, 3 (ATP)
. ,
.
(4)
.
30 (28 ) 3-7
4274/mm 6257/mm
, 1 7056/mm .
, , ,
( ) 58 41
5 . , , ,
( ) 13
.
(, , , , ) 17 ,
16 . , , , , 30
27 . , 70 ,
3 57. , , , ,
, , , , 86 ,
94%, 36 88.9% .
,
.
. ,
.
(5)
15-30g, .
@ff
3
1.
Rehmannia glutinosa (Gaertn.) Libosch.
f.hueichingensis (Chao et Schih) Hsiao R.glutinosa (Gaertn.)
Libosch., . , ,
.

(1)
: catalpol, aucubin .
: -sitosterol .
, : D-glucose, D-galactose, D-fructose, sucrose, raffionse, stachyose
: arginine, mannitol

(2)
, ( ).
. , .
(3)
. () ,
. '', (
... ) .'' ( ,
'' (...
) . '' (
) . , (
) ('').
(4)
#1
- , 1
17- (P
< 0.01). , (, , ,
) ,
17- .
- .
-
.
- , , ( 3, , , , ,
2, 1)
,
.
C .
-
.
#2
- , , , -
.
- , , , (, , , , ,
) .
- ,
, C4: 5 A C3
C17, 21 20
. (,
).
-

. ,
. ,
30g, 9g, 9g 1-3
30-40ml/ 2 14 8
, , ,
.
#3

. ,
. ( )
.
#4
.
. , ,
, -

(Ig)A, IgG . ,

 . .
#5
N-
.
, ,
/ . ,

.
,
.
.
#6
() (, , ,
) , . , ,

.
, .
#7
, () ( ), ( )
() .

.
(5)
, I-IV ,
.
#1
90g 12 .
11 3 . 11 10
5 . 23 3
. ( ) 1
.
#2
( )
.
83 , 5-40 (1-2 1) 83%.
.
#3 , ,
- 2, 4ml , 1, 20-40ml 5%
( )
73 14
19.2%, 40 54.8%, 16 22%, 96%.
- 90g , 3 3 , 3 7
, 3 14 3 1-2
, , 37 , 28, 3,
5, 1.
- ( 18g, 18g, 15g, 18g, , ,
4.5g, 9g, ) 0.5-10
14 , 10 (2 8), 4.
( ) .
#4
(, 2g/ml) 3 , 2
. '' 25-30g (36-72g ),
, 7-11g () (
) .
#5
( 12g, 6g )
1, 10 1 , ,
50 , 41, 7, 2
- (GPT) .

 12g, 6g 10 .
2ml 2g , 1-2
20 11 .
#6
11 6 ,
4, 1 .
. ,
.
#7
,

. ( )
. .
#8
- , ,
, .
- ,
.
- , , ,
.
- .
, , , . ,
.
(6)
10-30g,
(7)
, ,
2.
Schisandra chinensis (Turcz.) Baill.,
.
(1)
: citral, -chamigrene, -chamigrenal, sesquicarene .
: schizandrin A-D, deoxyschizandrin, gomisin A-D F-H, J, pregomisin .
: citric acid, malic acid, tartaric acid, protocatechuicacid, ascobic acid
.
(2)
. , , , .
(3)
.
'' (
) . '', (

.
.)
(4)
#1
.
.

.
#2
.
.

 .
#3
, , A,
B ,
GPT .
.
B, C, B P-450
. P-450
, . ,
B
.

.

.
#4
.
#5
, .
-
.
- ,
.
- , ,
.
#6

.
(5)
#1 , , . 100 , 65.
#2
( )
, .
373 , 1 -GPT 316 84.3% .
374 19 331 -GPT .
wp 400 ,
8 -GPT 96% .
, 400 , 2 -GPT 235
58% , 355 88% .
-GPT .
#3
- 60g 27 , 1 5
25 .
- 33 ( 11 1-3 1-4
, 20 ) , 29,
3.
- 21 ( 14, 5)
20
- 10 , . 1-4
.
#4
, , .
. , , .
.
-237
, -GPT
(P < 0.01). .
, , , .

(6)
#1 5-10g
#2 : 3-6g, 3.
#3 : 0.15g ( 2.2g
) 2-3, 3 .
(7)
, , , .
3.
Cornus officinalis Sieb. et Zucc.
.
(1)
: morroniside, loganin, sweroside .
: ursolic acid .
: cornin .
: tellimagrandin I, II, isoterchebin, cornusiin, A, B .
: tartaric acid, malic acid, gallic acid .
: oleanolic acid, A
(2)
. '' (
) .
(3)
#1
(P < 0.001).
#2 .
#3
, 0.1%
.

.
(4)
#1
, . ,
. , .
#2 , , ,
.
#3 .
'' (
), ( ,
, ,

, ,
. 60g ( ), 30g ( ), 30g ( ),
18g, 12g, 9g ( )) .
, ,
, .
(5)
6-12g, .
(6)
, , .
4.
Ligustrum lucidun Ait.,

.
(1)
( 14%), , , , , d-mannite, oleic
acid, linoleic acid .
(2)
. , .
(3)
. '' (
,
) .
'' (
.

. ) . (
) .
(4)
#1

(P < 0.05-0.001).
#2
- 100% 0.5ml, 1,
4
(P < 0.05), (P < 0.001).
3 ,
.
- ,
, (P < 0.001,
(PHA)
. ( ), (
) .
#3

.
(5)
#1
, ,
29 , 10, 16, 3.
(, , , , 1 2.4g ,
4, 3) ( )
, 24 18
15 .
.
#2 ,
, , 6g/ , 8 0.5-6
25 ( . , , , )
18 4.4g 3cm
.
'' (), ()
.
, , , , , ,
.
5.
Eclipta prostrata L. (E. alba (L.)Hassk),
.

(1)
, , , , , , A.
(2)
. , .
(3)
. .
'' ( ... ) .
(4)

(LPS) 2.5.
.
(5)
#1
''
.
.
30-50ml, 3-4 20 ,
9 ,
() 8 , . 5
. (, , ,)
143 , 5.3,
#2

2947 .
2-3 . ( 8kg
3kg 500ml 75g
1500ml ) 350 2-4
.
50 . 138 ,
98.5%.
,
.
(6)
15-30g, , .
6.
Opliopogon japonicus (Thunb) Ker-Gawl.
Liriope spica Lour. , .
(1)
: ophiopogonin A-D ,
: ophiopogone A, B , , ,
-, -D-, A .
(2)
. , , .
(3)

.
(4)
#1 .

 3 .
, AFP
( ).
#2
() ( ) ()
. ,

.
#3

.
.
#4
- (, , , , )
() .
- .
-
.
,
, .
(5)
248 , . 235
, 3 94.1% .
, , , , , , ,
, . .
(6)
5-15g, .
(7)
, , , , , , ,
, , , .
7.
() Asparagus cochinchinensis (Lour)
Meer., .
(1)
-sitosterol , protosarsasapogenin
4 Asp-IV, V, VI, VII glucose, fructose,
5-methoxymethylfurfurol, , aspar-agine .
(2)
. , .
(3)
. . (
) .
(4)
#1

3 .
. (, , , , )
AFP .
#2
.
, ,
.

(5)
#1
, 52 30
16, 5, 1 .
42 , 16, 8, 11,
7.
#2

26 , 9 ( 1 , 2 ),
7, 8, 2. 15
.
#3
23 , 5,
7, 7, 4. 18
1-2
.
, ,, , , , ,,
.
(6)
#1 : 5-15g.
#2 : 20-40g, 50% 20-40ml
.
#3 100% : 10ml 3.
(7)
, .
8.
Scrophularia ningpoensis Hemsl. .
(1)
, fructose, glucose, oligosaccharide, stacyose,
-O-cinnamate (=harpagoside) - O - Rho - methoxycinnamate
4:1 . , phytosterol . S. nodosa L.
harpa-gide aucubin .
(2)
. , .
(3)
. '' (
) .
(4)
#1
.
#2 (, , , , ) (AFP)
.
() . (
).
#3 , ( ),
() . , , ,

.
(5)
#1 , ,
. 213 ,

 140, 3. ,
. ( ). , ,
, . (). ''
(, ) .
#2 , , , ,
, , , , ,
() .
(6)
6-15g, .
9.
Agkistrodon halys (Pallas), Zaocys dhumnades
(Canton) Natria tigrina lateralis , ,
.
(1)
, , , , , ,
, - .
(2)
. , , .
(3)
.
(4)
#1 -
- ,
.
- , ,
. , ,
C .
,
(ACTH) ACTH
.
- (
.)
ACTH .
.
- 17-
. (P < 0.01).
, - - .
#2
- ,
.
, .
-
( ). .

.
. ,
.
(5)
#1
( .) 5, 0.3g , , ,
, , 84 , 37,
29, 7, 86.9%.
#2

- , (
.) 3, 1 1g, 2 2g, 3 3g
, 2g, .
1 3-6, 100
87, 8. 5ml
58 , 12, 34, 7,
2, 3.
- 2, 2-5ml, 3 1
100 ,
, 65
. 26, 62,
12. .
.
- 2-5ml, 2, 1 2
103 ( 53, 50) , 75.7%
28%, 40%. .
- 112 , 1 ,
22.3%, 34.9%, 32.1%, 89.3%.
. ,
, ,
.
#3
124 , 82.3%,
. (P < 0.05).
#4
31 , 12, 9, 10,
. 10
.
#5
. . ,
, . , ,
, .
.
, .
.
(6)
.
,
.
(7)
#1 : 10-30g
#2 : . 2-5g. 3.
#3 100% ( ) : 2-5ml, 2, .
@ff
4
1.
Epimedium gradiflorum Morr, E.
sagittatum (Siet.et Zucc.) Maxim, E.brevicornum Maxim. E.
koreamum Nakai, .
(1)
icariin, .
(2)
. .
(3)
. '' (

) '' ( ) .
(4)
#1 ()
17-
. , 17-
. .
. (P < 0.001).
.
() (,
, , ) ,
.
.

, .
( ), (
) . ' ' (
) .
#2 ,

.

.
#3

.
.
#4
-
.
- .

.
- ()
,
.
-
sIgA (P < 0.05).
- ( I ) (, , , , )
.
(P < 0.01).
(P < 0.01).
(5)
#1
1066 , 10 1 74.1%
1 . 30 540 ,
87-96% . , , .
#2
34 ,
24, 33. 143, 114. , ,
, ,
10-60 38 ,
27, 10, 1.
.
(6)
#1 : 3-10g
#2 (): 1 0.3g ( 2.7g ),
5-7, 2.

#3 200% : 1 2ml, 1, 2, .
(7)
.
2.
Psoralea corylifolia L., .
(1)
. , , , 8-, ,
, (), . 8-
., 8- .
psoralen: R = H
8-methoxy psoralen: R = OCH3
(2)
. .
(3)
. '' ( )
, '' .
(4)
#1

. ()
.
. '' ( )
.
#2
1 1, 0.5ml 4

(P < 0.05).
#3 .
,
2 . (. ,
) 10 (Ig)
. IgG 18.00 (mg/ml, ) 13.70
( 12 +- 26) , IgA 2.87 1.98 . ( 12
+- 0.5), IgM 2.09 1.30 ( 1.1 +- 0.3).

.
#4

.
#5

, ,
.
(5)
#1
6-18g 3g 1 4
19 , 14, 4. ,
. , .
#2
. .
-
.
, , . 2

 , , 2-3
10-20 207 ( 176 1 )
, 39.7%, 38.7%, 21.5%, 7.8%.
1 13 , 3.6%, 23.4%,
41%, 32%, . 40
, 23, 11, 3 .
#3
,
155 , 47.7%, 34.2%, 10%,
7.7%. 8- 184

80.3%, 97.8%. 27 25
. ,

.
.
#4
( 95 1
) , 2 1, ,
53 .
50 , 3 . , , .
#5
'' () . 4ml
( 8g ) 30 ,
26, .
, , , .
#6
,
() ('') , ,
.
(6)
#1 : 5-10g
#2 : 2-3g, 2-3
#3 : 2ml 2mg .
2mg, 2-3, .
#4 (): 2ml , 2.5g
1, 2-3, , 20-40mg .
#5 8- (8-MOP): , 30mg, 1, 2-3, .
30mg, 30mg, 2, .
(7)
,
3.
Acanthopanax senticosus (Rupr. et
Maxim.) Harms (Eleutherococcus senticosus Maxim),
( .
, A.gracilistylus W.W.Smith A.graciliflorum
Seem.
).
(1)
, - - , 7 - - 6, 8 - - D - , - - D - , - - D (2 ), ( ), , , ,
. , A, B . periplocin
. , , , 10 .
(2)

, . , .
(3)

.
'' ( ) '' (
) . (
,
), ( ,... )
('' ()), '' ( ) .
(4)
#1
(, )
, .
.

.
. ( ) .
( ) ('')
.
#2
,
.

.
. ( ), (
) . () ('') ()
(''), () ('') .
#3
-
.
- , ,
.
- ,
15% .
( ) (,
) ('') .
#4
- .
.
- .
, , ,
,
.
- .
, , ,
.
- .

.
.
- () , ,
()
, , ,
.
.
#5
- .
- .

-
, .
- .
#6
- 180
, .
- , 6- ,
, .
-
. ,
.
, ,
.
, , , ,
. ( )
.
(5)
. 100mg/kg 2
. 350g/kg
. 500g/kg
10 1
.
(6)
#1
43 ( ,
37, 3, 3, , 3.6kg, 3-15
, 70.4% 2 .
2
. 1978 10, 113 ,
,
13.7%, 74.5%.
#2
''
.
, . 50 ,
.
#3
100 , ,
.
#4 .
(6)
#1 : 5-10g
#2 : 1 0.3g, 5, 3.
4.
Eucommia ulmoides Oliv.,
. ,
.
(1)
guttapercha 6-10% ( 10-12%)
, (, ), chlorogenic acid, , , ,
, C . linolenic acid, linoleic acid, oleic
acid, stearic acid, palmitic acid .
(2)
. , .

(3)
. ''
( ) .
( ) .
'' ( ) .
(4)
#1 -
, ,
. - .
#2
,
.
#3
, ,
. .
#4
,
.
#5

.
(5)
#1 , ,
. '' ( ''
,
.
... .
)
. .
#2
'' , ,
. , Rh
. '' , .
() () .
(6)
10-15g, .
(7)
, , .
5.
Aconitum carmichaeli Delx,
. () .
(1)
: aconitine, mesacontine, aconine, hypaconitine, jesaconitine,
atisine, songorine, kobusine, ignavine, napelline, higenamine, (dl-demethyl
coclaurine), coryneine, yokonoside .
(2)
. , , .
(3)

. '' (
) .

(4)
#1
- , , C
,
. C
.
- 17 -
.
-
( ).
- ,
(
), .
. -
( )
.
( ).
#2
, , ,
( )
, .
, 5- ,

.
#3
.

.
cAMP
.
(5)
, .
120C 40 5 1 350
1. 0,295mg/Kg (LD50).
. ,
, .
(6)
#1
'' (
). '' , , ( )
.
.
.
#2
, .
. '' () (
) . 50
, 29, 45.
.
(7)
#1 : 10-15kg
#2 : 1mg 10% . 1 1
#3 : 1 100ug 100-300ug 5-10% 500ml
. 1 1.
(8)

, , .
6.
Cinnamomum cassia BL,
.
(1)
: cinnamic aldehyde, o - methoxycinnamic aldehyde, cin-namyl acetate,
phenylpopyl acetate .
: cinncassiol A, cinncassiol A 19-glucoside, cinn-zeylanol,
cinnzeylanin .
: D-glucose, D-fructose, sucrose.
: .
(2)
. , , .
(3)

. '' ( ,
) . ( ,
) , (, ...
) .
(4)
#1
- ,
C .
.
- (
) .

. 4 C14- ,


.
- , 17 -
. .
#2
, .

, .
.
.
. ,
.
. .
. '' (
) .
#3 ,
, ,
.


.
#4
, , , , AFP
.
#5 B .
#6 () (

).
#7
- 0.1% 75%
, .
- Forssman
.
.
Arthus

,
.
(5)
#1
'' () .
21 , 19
, 1 .
, ,
. , .
#2
, , , ,
, . (
).
#3
.
( ) ''
( ) , , .
(6)
0.5-1.5kg, .
(7)
, , , , , ,
, , , , , ,
.
@ff

.
.

. .
.
,
.
.
.
1.
1) .
(1)
#1 , , ,,
(PHA), , , , , , , , , ,
, , , , .
#2 , , ,
. , , , , ,
, , , , , , , , , .
(2) T
#1 T , , , ,
(PHA), , , , , , .
#2 , , , , , ,
, , , , , , , , , ,

.
2) .
(1)
#1 ,
, .
#2 C3
.
(2)
#1
, , , , .
#2
, , , , , , , , ,
, .
#3 , , , ,
, , , , ,
, , .
#4 sube class
.
6.
(1. 2. )
IgG: 1. , , 2.
IgA (): 1. , 2.
IgA (): 1. , , ,
IgM: 1. , 2.
IgE: 1.
2.
1) I ()
(1) (, SRS-A) .
(2)
, , , , .
(3)
, , , .
(4)
, , .
(5) ,
, ( ,
,
).
2) II ()
Rh . ,
, , , ,
, , .
.
3) III ()
, , .
4) IV ()
, I (, ) .
5) , , ,
, , , , , .
3. ,
1) - , , , ,
, , , , , , .
, .
, .
.
2) , .

3) , , , , , ,
.
.
4) , , .
4. cAMP
1) cAMP .
2) , , , , cAMP
cAMP .
5.
1)
(1) , , , .
, , , , , ,
.
(2) , , ,
, , , , .
(3) , , , , , ,
, , , , , .
(4) , , , ,
, , .
(5) .
(6) .
(7) , .
(8) .
(9) , , , , .
(10) .
(11) , .
(12) , , .
(13) (SLE) , .
(14) .
(15) .
(16) I (,
), .
(17) , , , , ,
.
2)

.
(1) , , , , ,
.
(2) , , , (PHA), , ,
.
(3) , .
(4) , , .
(5) .
(6) , .
3)
, ,
.
. IV
.
@ff
@ff
:
:
:
: 1994

 : 149-5 2
: 738-7340
FAX: 720-6365
: 300
:
: 1995 5 30-96 6 16
:
: 1997 11 20-97 12 5
:
: 3 1254-3
: 338-0017-9
@ff
@ff