BLOK 19 HEWAN KESAYANGAN II UNIT PEMBELAJARAN 2

DISUSUN OLEH : Cik Sasmi Budi Prawirasari 10/300080/KH/06610 KELOMPOK

FAKULTAS KEDOKTERAN HEWAN UNIVERSITAS GADJAH MADA YOGYAKARTA

2013
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1! S"#u$ka% &"%'aki$ (ira) *as$r+i%$"s$i%a) &ada a%,i%-. ! Ba-aima%a "$i+)+-i/ &a$+-"%"sis/ -",a)a k)i%is/ &"ru#a0a% &a$+)+-is/ dia-%+sis/ di11"r"%sia) dia-%+sis/ $"ra&i da% &"%a%-a%a% dari &ar(+(irus.

Pe(#a)a*a
1! P"%'aki$ (ira) *as$r+i%$"s$i%a) &ada a%,i%! Ca%i%" &ar(+(irus 2CP34 a+ E&!,-,"! Ca%i%" &ar(+(irus masuk da)am 1ami)' Par(+(irida"/ m"ru&aka% (irus %+%5 "%(")+&"d/ diam"$"r%'a s"ki$ar 185 6 %m! *"%+m%'a ada)a0 )i%"ar m+)"ku) si%-)"5s$ra%d"d DN6 2ssDN64! 7ami)' Par(+(irida" i%i k"#a%'aka% m"%-i%1"ksi 0"wa% ("r$"#ra$a 2C+))i"r/ L 8 Ba)+wsm 68 Sussma%/ M! 19984! Berikut bagan dari family Parvoviridae

2:ui%%/ dkk 0104 Da)am 1ami)' Par(+(irida" ada dua su#51ami)'/ 'ai$u su#1ami)' Par(+(iri%a" 'a%m"%'"ra%- &ada ("r$"#ra$a da% D"%s+(iri%a" 'a%- m"%'"ra%- &ada ar$0r+&+da! Namu% 0a%'a -"%us Par(+(irus 'a%- m"ru&aka% (irus &"%$i%- da)am du%ia ("$"ri%"r 2:ui%%/ 0104! CP3 $"rmasuk (irus 'a%- m"mi)iki k"s$a#i)a% )uar #iasa! Ia $a0a% &"r)akua% d"%-a% ;aira% )i&id/ &"ma%asa% 0i%--a 60OC da)am wak$u 60 m"%i$/ &H kisara% 359 da% 0i-05sa)$ ;+%;"%$ra$i+%! Si1a$5si1a$ i%i s"maki% m"m#ua$ CD3 susa0 u%$uk di ")imi%asi 2C+))i"r/ L 8 Ba)+wsm 68 Sussma%/ M! 19984! Ia ,u-a 0a%'a #"r"&)ikasi &ada %u)k"us s") 'a%- s"da%- #"r"&)ikasi
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#+ Pa&,"e e*!* S&"k$rum CP3 dari aku$/ a1i%i$as )"$0a)/ $"rkada%- kr+%is! *am#ara% k)i%is dari &"rk"m#a%-a% i%1"ksi dari sa$u a$au #a%'ak ,a)a% da&a$ sa)i%- m"m&"%-aru0i/ 'ai$u s"&"r$i -"%"$ik 0+s$/ s") 'a%- #"r#"da dari ,ari%-a% &r+)i1"rasi/ r"s&+% imu% i%di(idu $"r0ada& +r-a%ism"/ da% "&id"mi+)+-i dari si$uasi )i%-ku%-a% 2C+))i"r/ L 8 Ba)+wsm 68 Sussma%/ M! 19984! S")ai% i$u 1ak$+r usia ,u-a m"m&"%-aru0i/ kar"%a dasar%'a %+ Ge$a-a .-! !* Usia da% s$a$us imu%i$as dari 0"wa% sa%-a$ m"%"%$uka% &ara0%'a &"%'aki$! S"$")a0 masa i%ku#asi 'a%- &"%d"k s")ama $u,u0 0ari/ 0"wa% d"%-a% &"%'aki$ "%$"rik m"%u%,ukka% $i#a5$i#a +%s"$ (+mi$i%- a$au 1as" mu%$a05mu%$a0 da% a%+r"<ia! D"&r"si da% d"mam #isa ,u-a %am&ak! Diar" #"rd"ra0 s"$")a0 =8 ,am da% da)am k")ukaa% &ara0/ $"rda&a$ 0"m+rr0a-" 'a%- ,")as! 7"s"s #"r#au 7+"$id! Da)am k+%disi i%i #isa ,adi i%1"ksi s"ku%d"r/ #aik (irus )ai% mau&u% #ak$"ri 'a%- aka% s"maki% m"m&"r#uruk k+%disi 0"wa%! H"wa% 'a%- $"ri%1"ksi d"%-a% ;"&a$ aka% m"%u%,ukka% -",a)a d"0idrasi da% k"0i)a%-a% #a%'ak #"ra$ #ada%! >ika k"saki$a% #"r)a%,u$ d"%-a% sa%-a$ #uruk8 0"wa% 'a%- $"ri%1"ksi #iasa%'a ma$i da)am $i-a 0ari! H"wa% 'a%- #"r$a0a% d"%-a% &"r%'aki$ i%i aka% m"%-"m#a%-ka% )+%-5 )as$i%immu%i$' 2:ui%%/ 0104! Di da)am m'+kardium/ 0"wa% muda 'a%- $"rs"ra%- #iasa%'a m"%u%,ukka% -",a)a -a-a)%'a ,a%$u%- s"#")um d")a&a% mi%--u usia%'a! B"#"ra&a &u&&i"s mu%-ki% #"rk"m#a%d"%-a% ,a%$u%- 'a%- rusak #"#"ra&a #u)a% s"$")a0 i%isiasi i%1"ksi/ s"#a-ai 0asi) dari %"kr+sis m'+;ardia) m"%-iku$i 1i#r+sa 2:ui%%/ 0104 d! P"ru#a0a% &a$+)+-is
On farms where the disease is endemic, many sows are immune. They remain seropositive for up to four years and transmit passive protection through colostrum to their piglets. Maternally-derived immunity usually persists for about four months, but it can persist in some pigs until they are six to nine months of age. uring this period, the maternally-derived antibodies may interfere with the development of active immunity and conse!uently some gilts can be seronegative and susceptible to infection at mating. "nfected pigs shed virus in their faeces and other secretions, including semen, for only a few wee#s. $owever, pens may remain contaminated for several months because of the exceptional stability of the virus.

"! Dia-%+sis
%hen reproductive failure is detected in young or

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recently introduced sows, particularly if associated with mummified foetuses, infection with porcine pawovirus must be considered. 'everal foetuses should be submitted for laboratory examination. emonstration of viral antigen in cryostat sections of foetal tissues, particularly in the lungs, by immunofluorescence is reliable and sensitive. (gglutination of guinea-pig erythrocytes by homogenates of foetal tissue indicates the presence of viral haemagglutinin. 'wine #idney cell lines may be used for virus isolation. $owever, viral infectivity is gradually lost following death of the foetus and isolation from mummified tissues may be unsuccessful. 'erological techni!ues include $() and *+ tests. (ntibodies may be detected in sera or body fluids of older foetuses or aborted piglets. $owever, serological testing is usually of little diagnostic value in endemically infected herds.

1! Di11"r"%sia) dia-%+sis -! ?"ra&i da% &"%a%-a%a%

,ontrol in herds in which the disease is endemic is based on exposure of gilts and susceptible sows to porcine parvovirus prior to mating, thereby inducing immunity. *accination can be used to enhance immunity in herds with endemic disease. "t can also be used for male or female breeding stoc# introduced into these herds. +atural exposure can be achieved by increasing the contact between susceptible gilts and older seropositive sows. Methods of stimulating immunity include exposing animals to contaminated faeces or to placental or foetal tissue from infected sows. Modified live and inactivated vaccines against the single serotype of porcine parvovirus have been deviloped experimentally, but only inactivated vaccines are available commercially. -ilts and susceptible seronegative sows and boars should be vaccinated two to four wee#s before mating. *accination prevents intrauterine infection for a limited period. Most vaccination strategies rely on subse!uent natural exposure to the virus to reinforce immunity .$uysman et al., )//20.

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