Tiempo (dias)

tiempo en horas
0
1
3
6
9
12
15
17
21

X (g/L)

0
24
72
144
216
288
360
408
504

500 tons de acido lactico

0.03
0.04
0.06
0.09
0.14
0.32
0.73
0.89
1.03

Ln X
S (g/l)
-3.5065579
-3.21887582
-2.81341072
-2.40794561
-1.96611286
-1.13943428
-0.31471074
-0.11653382
0.0295588

P (g/l)
0.23
0.41
0.57
0.95
0.93
3.36
4.13
4.5
4.63

4.63

ejercicio

0.00844719 0.00613657 horas

82.056542 horas
5.10153803 generaciones

max
td
ng

-1

Chart Title
0
-0.5 0

Axis Title

-1
-1.5

100

200

300

400

500

y = 0.0083x - 3.5099
R = 0.9887
Series1

-2

Linear (Series1)

-2.5
-3
-3.5
-4

Yx/s (gx/gs)

150
147
139
124
118
92
63
49
35

Axis Title

0.00333333
0.00272727
0.00230769
0.0034375
0.005
0.00804598
0.00851485
0.00869565

Yp/s (gp/gs)

Yp/x (gp/gx)

0.06
0.030909091
0.027692308
0.021875
0.053965517
0.044827586
0.042277228
0.03826087

18
11.33333333
12
6.363636364
10.79310345
5.571428571
4.965116279
4.4

Px

Pp

0.000277778
0.000357143
0.000384615
0.000482456
0.000966667
0.00188172
0.002047619
0.001937984

0.005
0.004047619
0.004615385
0.003070175
0.010433333
0.010483871
0.010166667
0.008527132

valores maximos
Valores globales

Chart Title
516
12

tiempo

Ln X
0
24
72
144
216
288
360
408

-3.5065579
-3.21887582
-2.81341072
-2.40794561
-1.96611286
-1.13943428
-0.31471074
-0.11653382

Axis Title

ttotal

1
0.5
0
-0.5 0
-1
-1.5
-2
-2.5
-3
-3.5
-4

100

200

y = 0.0076x - 3.4208
R = 0.9746
300
400
500

Axis Title

500

600
Series1
Linear (Series1)

se quieren producir 500 toneladas de acido lactico

500
si en un poceso de 15 dias en un reactor de 100 L se producen
500000000
4.13 g/l
entonces el diseo del reactor para la produccion de 500 ton. queda de la siguiente manera
4.13 g
500000000 g
Vol total =
Vol total =
Vol op.
Vhold up

1l
121065375.3 litros

VO+VHOLD UP

CALCULOS VOL
100%
151331.7191
80%
121065.3753
20%
30266.34383

Vt =
VolCil+ volts+ voltinferior
Vol cilindro =
vol tapa superior =
Vol tapa inferior =
volumen total
H

75%
10%
15%
151,332

D
2

D=
H=

vol. Tap. Sup. =esferica

1/12D^3
vol esfera
Vol. Tap. Sup. =

41.64
83.27
un doceavo
PI

18895.31

1/12h(D^2 +d^2 +Dd)

22699.76 m^3
41.64 m
0.0508 m
1733.49919085132 m^2
0.00258064 m^2
2.115073841 m^2
49.95727505 m

vol cono truncado

vol cono truncado
D
d
D^2
d^2
Dd
h

vol op
Vol ti
vol liq cil
Vol cil

CALCULOS
corregido
113498.79
15133.17
22699.76
m^3

121065.3753
18,937.62
102,127.76
113498.79

HL
HL
Pi
D^2

4 (vol liq cil)/piD^2

75.01191896
3.141592654
1733.49919085132

geometria interna
(HL-Di)/Di
(Hl-Di)/2Di

Di/Dt

Hl/Dt
0.33

Li/Dt
1

Wi/Di
0.25

0.2

Di<Hi<2Di
Elnumero de paletas esta determinado por

Di
Li
Wi
Wo

el numero del paletas esta dado por

(HL-Di)/2Di<Ni<(HL-Di)/Di
2.20246273 <Ni<
2

4.404925459
4

13.88
3.469609319
2.775687455
1.387843728

TON
GRAMOS
uiente manera

FACTOR DE CONVERSION

Vol m^3
1 l=

1000000 GRAMO
relacion vol esfera/ volumen cilindro
16.65%

121065.3753 m^3
0.001 m^3

75%
12%
13%

113498.79
18895.31
18,937.6167307612

0.0833
3.1416

h=

Vq = 1/3h^2(3re-h)
De > Dt

12 Vol.tapa inferior/pi* (D^2+d^2+Dd)

m
m
m^2

H0/Di

N0
1

Wo/Dt
4

0.1

Dt/2=R

m
m
m
m

Dt/2=R

re

De=
D=
De=
Re=
vq
h
Vq Iterc=
Vq-Vq Iter=

2D
41.64
83.2706237
41.6353118
18895.31
12.67 Susministrar el dato
18867.4748
27.84

tiempo en horas

sustrato (Bx)

0
6
12
18
24
32
40
48
56
64
70
Yp/s

Yx/s
0.00
0.10
0.20
0.19
0.18
0.17
0.24
0.29
0.32
0.30

p
E
I
D
TOTAL

20
19.7
19
17.5
14.2
10.7
6.8
4.5
3.2
1
0.3

biomasa (cel/ml)
X (g/L)
5.00E+03
5.00E+03
6.00E+03
1.20E+04
1.20E+04
3.20E+04
9.20E+04
1.70E+05
6.70E+05
1.10E+06
1.10E+06
Yp/x

0.00
0.00
0.00
0.00
0.00
0.00
0.00
0.01
0.02
0.02
2
4
1
5
12

0.015
0.015
0.018
0.036
0.036
0.096
0.276
0.51
2.01
3.3
3.3

Px
#DIV/0!
333.33333
238.09524
523.80952
209.87654
88.12261
74.74747
24.56140
18.56925
18.26484

0
0.000125
0.0007
0.00058333
0.00184091
0.00501923
0.00825
0.02933824
0.04322368
0.04006098

Ln X
S (g/l)
-4.19970508
-4.19970508
-4.01738352
-3.32423634
-3.32423634
-2.34340709
-1.28735441
-0.67334455
0.69813472
1.19392247
1.19392247
Pp
0
0.04166667
0.16666667
0.30555556
0.38636364
0.44230769
0.61666667
0.72058824
0.80263158
0.73170732

200
197
190
175
142
107
68
45
32
10
3

tiempo
0
6
12
18
24
32
40
48
56
64
70

P (g/l)
0
0
1
5
11
17
23
37
49
61
60

Factor de conversin
100000 cel/ml
6.70E+05 cel/ml

calculos
1 Bx (g/L)
LN 2

2.01
0.3
2.01

10
0.69314718

CURVA DE CRECIMIENTO
2
1

24
32
40
48

LN X
-3.32423634
-2.34340709
-1.28735441
-0.67334455

valores globales
Valores mximos

max
td
ng

0
-1

10

20

30

40

-2
-3
-4
-5

Chart Title

0.12260366 1/h
6h
8 GEN.

0
-0.5
-1
Axis Title

TiEMPO

10

20

30

y = 0.1126x - 5.961
R = 0.9885

-1.5
-2
-2.5
-3
-3.5

Axis Title

40

gr/l
gr/l

A DE CRECIMIENTO

40

50

60

70

80

Chart Title
40

50

60

Series1
Linear (Series1)

se quieren producir 20 toneladas de L-Lisina

20
si en un poceso de 64 horas en un reactor de 100 L se producen
20000000
61 g/l
entonces el diseo del reactor para la produccion de 500 ton. queda de la siguiente manera
61 g
20000000 g
Vol total =
Vol total =
Vol op.
Vhold up

1l
327868.8525 litros

VO+VHOLD UP

CALCULOS VOL
100%
409.8360656
80%
327.8688525
20%
81.96721311

Vt =
VolCil+ volts+ voltinferior
Vol cilindro =
vol tapa superior =
Vol tapa inferior =
volumen total
H

CALCULOS
75%
10%
15%
410 m^3

D
2

307.38
40.98
61.48

D=
H=

vol. Tap. Sup. =esferica

1/12D^3
vol esfera
Vol. Tap. Sup. =

5.80
11.61
un doceavo
PI

51.20

1/12h(D^2 +d^2 +Dd)

61.48 m^3
5.80 m
0.0508 m
33.69366626805 m^2
0.00258064 m^2
0.294874928 m^2
6.908238264 m

vol cono truncado

vol cono truncado
D
d
D^2
d^2
Dd
h

vol op
Vol ti
vol liq cil
Vol cil

corregido

327.8688525
51.26
276.61
307.38

HL
HL
Pi
D^2

4 (vol liq cil)/piD^2

10.45281751
3.141592654
33.69366626805

geometria interna
(HL-Di)/Di
(Hl-Di)/2Di

Di/Dt

Hl/Dt
0.33

Li/Dt
1

Wi/Di
0.25

0.2

Di<Hi<2Di
Elnumero de paletas esta determinado por

Di
Li
Wi
wo

el numero del paletas esta dado por

1.93
0.483718713
0.386974971
0.193487485

(HL-Di)/2Di<Ni<(HL-Di)/Di
2.201161135 <Ni<
2

4.402322269
4

numero maximo de impulsores

4.402322269

TON
GRAMOS
uiente manera

FACTOR DE CONVERSION

Vol m^3
1 l=

1000000 GRAMO
relacion vol esfera/ volumen cilindro
16.66%

327.8688525 m^3
0.001 m^3

75%
12%
13%

307.38
51.20
51.2565322779

0.0833
3.1416

h=

Vq = 1/3h^2(3re-h)
De > Dt

12 Vol.tapa inferior/pi* (D^2+d^2+Dd)

m
m
m^2

H0/Di

N0
1

Wo/Dt
4

0.1

Dt/2=R

maximo de impulsores
aproximadamente

4 impulsores

Dt/2=R

re

De=
D=
De=
Re=
vq
h
Vq Iterc=
Vq-Vq Iter=

2D
5.80
11.6092491
5.80462456
51.20
1.765 Susministrar el dato
51.0506319
0.15