DRUG

PHARMACODYNAMICS

INDICATIONS

SIDE EFFECTS

CONTRAINDICATION

NURSING CONSIDERATION 1.Assess for liver and renal dysfunction 2. Culture infection, and arrange sensitivity tests before and during therapy if expected response is not seen. Warning: 3. Do not mix with aminoglycoside solutions, administer these drugs separately. 4. Powder and reconstituted solution darken with storage. 5. Have Vit. K available in case hypoprothrombinemia occurs 6. Discontinue if hypersensitivity occurs

Generic name: ceftazidime Brand name: Tazidime

Inhibits synthesis of bacterial c ell wall, causing cell death.

CNS infections

CNS: Headache, dizziness, the thargies, paresthesias GI: nausea, vomiting, anorexia, abdominal pain, flatulence, psuedomembranous colitis, liver toxicity

Contraindicated to patients with allergies to penicillins, cepahlosporins

Classification: Cephalosporins

GU: Nephrotoxicity