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Drugstudy Mupirocin ointment GENERIC NAME Mupirocin ointment CLASSIFICATIO N Topical ointment INDICATION > Impetigo caused by Staphylococcus aureus or Streptococcus pyogenes > Infected dermatoses CONTRAINDICATION > Skin lesions infected with Pseudomonas aeruginosa > Hypersensitivity to any of the drugs constituents ADVERSE EFFECTS > burning, stinging, erythema, dryness and itching > llergic reaction !hives, swelling, rashes, etc" NURSING RESPONSIBILITIES > Instruct patient on the correct application of the drug > dvise patient to apply the medication e#actly as directed for the full course of therapy > void contact with eyes > $atient should consult health care professional if symptoms have not improved in %&' days

Calcium pantothenate (Moriamin Forte) GENERIC NAME (alcium pantothenate !Moriamin )orte" CLASSIFICATION Multivitamins and minerals INDICATION >Malnutrition, protein and vitamin deficiencies > nemia > *estoration and maintenance of body resistance > $regnancy and lactation > d+uvant in the therapy of peptic ulcer and T, CONTRAINDICATIO N > Malabsorption syndrome ADVERSE EFFECTS > Hyper& vitaminosis NURSING RESPONSIBILITIES > Inform client that he-she may take the drug with food if .I upset occurs > Inform client that the drug may color the urine yellow and that this is normal

Paracetamol CONTRAINDICATION S > llergy to acetaminophen > 7se cautiously in patients with impaired hepatic function, chronic alcoholism, pregnancy and lactation ADVERSE EFFECTS > Myocardial damage > Hepatic to#icity and failure > cute renal failure, renal tubular necrosis NURSING RESPONSIBILITIE S > Teach client to not e#ceed recommended dose8 do not take for more than 9/ days unless directed by physician > Instruct client to avoid the use of other over&the&counter or prescription preparations containing acetaminophen as serious overdose may occur > Instruct client to report rash, unusual bleeding or bruising, yellowing of skin or eyes, changes in voiding patterns

GENERIC NAME $aracetamol !'//mg 0 1 for T > %2345("

CLASSIFICATION > nalgesic > ntipyretic

INDICATIONS Temporary reduction of fever, temporary relief of minor aches or pains caused by common cold or influen6a, headache, sore throat, toothache, backache, menstrual cramps, minor arthritis pain, and muscle aches

Warfarin CONTRAINDICATION S > $atients with coagulation disorders > $regnancy and lactation ADVERSE EFFECTS > ,leeding complications ranging from local ecchymoses to ma+or hemorrhage > Hepatoto#icity > ,lood dyscrasias > ;ecrosis > <asculitis > =ocal thrombosis NURSING RESPONSIBILITIE S > ssess hematocrit, platelet count, urine-stool culture for occult blood, ST, =T, regardless of route administration > ssess peripheral pulses8 skin for bruises, and petechiae > Instruct client to take the drug with food or after meals if .I upset occurs > Instruct client to take the drug as it is prescribed > Instruct client to avoid drinking alcohol and salicylates > Inform client that urine may become red&orange in color > Instruct client to notify physician if bleeding, bruising, red&brown urine, or black stools occur > >ducate client on the use of electric

GENERIC NAME :arfarin

CLASSIFICATION nticoagulant

INDICATIONS > $rophyla#is and treatment of venous thrombosis, arterial fibrillation with embolism, pulmonary embolism, ad+unct therapy in prophyla#is of systemic embolism after MI

ra6or and soft toothbrush to prevent bleeding Amlodipine CONTRAINDICATION S > Hypersensitivity to the drug or its components > Impaired hepatic or renal function > Heart&block > =actation ADVERSE EFFECTS > ?i66iness, lightheadedness, headache, fatigue, lethargy > $eripheral edema > )lushing > ;ausea NURSING RESPONSIBILITIE S > Monitor ,$ with postural changes3 *eport postural hypotension > Take after meals or with food if .I upset occurs > Instruct client to report significant swelling of face or e#tremities > Instruct client to have support when walking and standing due to possible di66iness > Instruct client to report shortness of breath, palpitations, irregular heartbeat, nausea, or constipation to physician

GENERIC NAME mlodipine

CLASSIFICATION > (alcium channel blocker > ntihypertensive > ntianginal

INDICATIONS > ngina pectoris due to coronary artery spasm > (hronic stable angina, alone or in combination with other agents > >ssential hypertension, alone or in combination with other antihypertensive

Insulin Isophane CONTRAINDICATION S > Hypersensitivity to pork and its products > History of smoking or lung disease ADVERSE EFFECTS > *ash, anaphyla#is > Hypoglycemia > ngioedema NURSING RESPONSIBILITIE S > Teach client how to administer insulin properly > Instruct client to rotate sites to prevent lypodystrophy > >ducate client to follow insulin schedule and avoid missing doses > Instruct client to roll vial between hands and avoid vigorous shaking

GENERIC NAME Insulin Isophane

CLASSIFICATION Insulin

INDICATIONS ?iabetes Mellitus

Ampici i! " Su #$ct$m %U!$sy!& CONTRAINDICATION S > Hypersensitivity to penicillin > Infectious mononucleosis ADVERSE EFFECTS > $ain at In+ site, thrombophlebitis, diarrhoea, itching, nausea, vomiting, flatulence, candidiasis, fatigue, NURSING RESPONSIBILITIE S > Instruct pt3 to immediately report signs and symptom ms of hypersensitivity reactio n, such

GENERIC NAME mpicillin @ Sulbactam !7nasyn"

CLASSIFICATION ntibiotic

INDICATIONS >(ommunity or hospital ac0uired pneumonia > >ndocarditis > Surgical prophyla#is

malaise, headache, chest pain, glossitis, abdominal distention, dysuria, urinary retention, oedema, erythema, epista#is, mucosal bleeding

as rash, fever, or chills3 Tell pt3 to report signs and sympto ms of infectio n or other proble ms at in+ectio n site3

Atorvastatin N$m' () Drug C $ssi)ic$ti(! I!dic$ti(! C(!tr$i!dic$ti(!s Sid' E))'cts Nursi!g R'sp(!si#i iti's

ATORVASTATI N ?osageA 1/mg B?

ntihyperlipidemi a

C )or patients at increased (< risk to the presence of HT; and dyslipidemia3 C Secondary prevention of the combined risk of death, non&fatal MI, cardiac arrest and re& hospitali6ation for angina pectoris3

C ctive liver disease !cholestasis, hepatic encephalopathy, hepatitis, and +aundice" C 7ne#plained persistent elevation of serum transaminases e#ceeding % times the upper limit of normal C $regnancy C =actation C 7se cautiously with impaired endocrine function3

C )lushing C )atigue C Headache C >dema C ?i66iness C bdominal $ain C ;ausea C $alpitations C Somnolence C Insomnia C .I disorders C =iver failure C Myalgia C sthenia

C Take drug once a day, at about the same time each day, preferably in the evening8 may be taken with food3 ?o not drink grapefruit +uice while taking this drug3 C Institute appropriate dietary changes3 C rrange to have periodic blood tests while taking this drug3 C Dou may e#perience these side effectsA ;ausea !eat fre0uent small meals"8 headache, muscle and +oint aches and pains !may lessen over time"3 C *eport muscle pain, weakness, tenderness8 malaise8 fever8

changes in color of urine or stool8 swelling3

Lactulose N$m' () Drug LACTULOS E ?osageA %/cc at hs hold if ,M less than or e0ual to E# B? C $ssi)ic$ti(! C ntidiarrheal C Bsmotic la#ative I!dic$ti(! C Treatment of constipation or hepatic encephalopathy !confusion, altered =B( and coma as a result of liver failure" C(!tr$i!dic$ti(!s C =ow galactose diet C Intestinal obstruction Sid' E))'cts C bdominal discomfort associated with flatulence or cramps C $rolonged use or large doses may result in diarrhea with e#cessive loss in water and electrolytes Nursi!g R'sp(!si#i iti's C >ffects are seen in E1&1F hours C ?o not self medicate with another la#ative because of slow onset C ;otify doctor if diarrhea persists for more than E1 hrs, could be a sign of overdose, and need for medication ad+ustment C ?iarrhea may indicate the dose is too high3 C >valuate therapeutic responseA decreased constipation or

blood ammonia level3 C ssess amount, colour and consistency of stool3

Ipatropium + Salbutamol (Combivent) N$m' () Drug IPATROPIUM " SALBUTAMOL %COMBIVENT& ?osageA 9 neb 0F5 C $ssi)ic$ti(! C ntiasthmatic C,ronchodilator I!dic$ti(!s C Management of reversible bronchospasm associated with obstructive airway diseases in patients who re0uire more than a single bronchodilator3 C (B$? C(!tr$i!dic$ti(!s C Hypertrophic obstructive cardiomyopathy or tachyarrhythmia3 C History of sensitivity to soya lecithin or related food products !soybeans, peanuts, etc3" Sid' E))'cts C )ine tremor of skeletal muscle C $alpitations C Headache C ,lurred vision C ?i66iness C;ervousness C ?ryness of mouth C Throat irritation C 7rinary retention C Special precautions to patients withA &insufficiently controlled diabetes mellitus, &recent MI, severe organic heart or vascular disorders &hyperthyroidism &pheochromocytoma &risk of narrow angle glaucoma &prostatic hypertrophy or bladder&neck obstruction &cystic fibrosis &pregnancy &lactation Nursi!g R'sp(!si#i iti's C (heck the heart rate before and after the treatment3

Sucralfate N$m' () Drug SUCRALFATE ?osageA 9gm-tab TI? C $ssi)ic$ti(! C ntacids C ntireflu# agents C ntiulcerants I!dic$ti(!s C Short&term treatment !up to F weeks" of active duodenal ulcer3 :hile healing with sucralfate may occur during the first week or two, treatment should be continued for 1 to F weeks unless healing has been demonstrated by #&ray or endoscopic e#amination3 CMaintenance therapy for duodenal ulcer patients at reduced dosage after healing of acute ulcers C(!tr$i!dic$ti(!s C Hypersensitivty to drug-classification-compo nent3 C ?ysphagia C.I obstruction C(aution in patients with renal failure, chronic Sid' E))'cts CSigns of an allergic reactionA hives8 difficulty breathing8 swelling of your face, lips, tongue, or throat C(onstipation C?iarrhea C;ausea C?i6iness C?ry mouth C.I disturbances C*ash C$ruritus Nursi!g R'sp(!si#i iti's CMonitor patient for constipation3 C dminister other medications E hours before sucralfate3

CHeadache C<ertigo C,ack pain

Losartan N$m' () Drug LOSARTAN POTASSIUM ?osageA '/mg-tab in M C $ssi)ic$ti(! C (ardiovascular agent8 C ngiotensin II receptor antagonist8 C ntihypertensive M'c*$!ism () Acti(! ngiotensin II receptor !type T9" antagonist acts as a potent vasoconstrictor and primary vasoactive hormone of the reninGangiotensinG aldosterone system3 I!dic$ti(! CHypertension C(!tr$i!dic$ti(!s C Hypersensitivity to =osartan, C $regnancy Hcategory ( !first trimester", category ? !second and third trimesters"I, C =actation C Muscle cramps C Myalgia C ,ack or leg pain C ;asal congestion C (ough C 7pper respiratory infection C Sinusitis Sid' E))'cts C ?i66iness C Insomnia C Headache C ?iarrhea C ?yspepsia Nursi!g R'sp(!si#i iti's C Monitor ,$ prior to a scheduled dose3 C Monitor drug effectiveness, especially when used as monotherapy3 C Inade0uate response may be improved by splitting the daily dose into twice&daily dose3 C =ab testsA Monitor (,(, electrolytes, liver J kidney function with long& term therapy3

AC (Fluimucil) N$m' () Drug ; ( !)=7IMI(I=" ?osageA 4//mg-tab 9 tab in half glass C $ssi)ic$ti(! C Mucolytic M'c*$!ism () Acti(! >#erts mucolytic action through its free sulfhydryl group which opens up the disulfide bon ds in the mucoprote ins thus lowering m ucous viscosity3 Th e e#act mechanism of action in acetaminophen to#icity is unknown3 It is thought to act by providing substrate for con+ugation with the to#ic metabolite I!dic$ti(!s C Treatment of respiratory affections characteri6ed by thick and viscous hypersecretions C cute bronchitis, chronic bronchitis and its e#acerbations C $ulmonary emphysema, mucoviscidosis and bronchieactasis3 C(!tr$i!dic$ti(!s CM B inhibitor the rapy within 91 days initiating therapy C Severe hypertension C Severe coronary artery dise ase CHypersensitivity to pseudoedephrine,ac rivastine or any component C *enal impairment C rthralgia C ,lurred vision C ?isturbances of liver function Sid' E))'cts C,ronchospasm C ngioedema C *ashes C $ruritus C ;ausea and vomiting C )ever C Syncope C Sweating C lso watch for increased blood pressure and hypo#ia3 CMonitor effectiveness of therapy and advent of adverse-allergic effects3 Instruct patient in appropriate use and adverse effects to report3 Nursi!g R'sp(!si#i iti's C?ue to the high doses re0uired, the patient should be watched for an over dosage of this medication, signs may include nausea and vomiting3

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