1\/^1) I1 1(1)I/ - ^1I1(1)/ (1I1)1)/)/ 2J1

1
UNIVERSITATEA DE $TIIN|E AGRONOMICE $I MEDICIN VETERINAR DIN
BUCURE$TI
FACULTATEA DE MEDICIN VETERINAR
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DISCILIN: II2ICA1CLCGIL
Cadru d|dact|c responsab||: Conf. dr. Gabr|e| Cotor
1LMA1IC ]I 8I8LICGkAIIL
1.Cap|to|u| VIII. I|z|opato|og|a ocu|u|
-vlll.1.LLlologla ;oculul, vlll.2.llzlopaLologla ;oculul, vlll.2.1.8eacla flzlologlc la agreslune,
vlll.2.2.8eacla paLologlc la agreslune. ag. 370 - 394 = 1oLal: 24 oe paglnl (LexL, Labele ;l flgurl).
2.Cap|to|u| kII. I|z|opato|og|a termoreg|r||
-xll.3.2.aLogenla reaclel febrlle, xll.3.3.SLaollle reaclel febrlle, xll.3.4.8esLrucLurrl meLabollce,
funclonale, hemaLologlce ;l lmunoblologlce ce insoesc reacla febrll. aglnlle S3S - S61 = 1oLal: 26
oe paglnl (LexL, Labele ;l flgurl).
1ota| pag|n| - S0 de pag|n| (text, tabe|e | f|gur|)
8lbllografle:
1.Dumitru C. Curc (2006) Tratat de Iiziopatologie general- Edi|ia a II-a, Editura Printech,
Bucuresti
SU8ILC1L
100 |ntrebr|, cu S var|ante de rspuns, d|ntre care DCAk o var|ant este corect (gr|| un|var|ant)
Nr.
crt.
Intrebarea cu var|ante|e de rspuns corespunztoare
1. Ccluzla lnLesLlnal lnouce sLare oe ;oc, consecuLlv:
a)colapsulul hlpovolemlc,
b)oepreslel nervoase,
c)oeprlmrll acLlvlLll meLabollce oxloaLlve,
o)ellberrll unel canLlLl crescuLe oe hlsLamln,
e)lnsuflclenel carolace.
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2. 5ocul hlpovolemlc poaLe fl cauzaL oe:
a)carolomlopaLll prlmare,
b)pneumoLorax,
c)lnfecll cu seuoomonas ssp,
o)vasoollaLall lnouse oe meolcamenLe (fenoLlazlne),
e)arsurl grave.
3. 5ocul carologen poaLe fl cauzaL oe:
a)Lamponaoa carolac,
b)vome severe,
c)lnfecll cu klebslella ssp,
o)vasoollaLall lnouse oe meolcamenLe (fenoLlazlne),
e)parallzll vasomoLoare.
4. 5ocul enooLoxlnlc poaLe fl cauzaL oe:
a)carolomlopaLll Loxlce,
b)pneumoLorax,
c)lnfecll cu Lscherlchla coll,
o)vasoollaLall lnouse oe meolcamenLe (fenoLlazlne),
e)hemoragll.
S. 5ocul neurogenlc poaLe fl cauzaL oe:
a)coagulopaLll,
b)lnLoxlcall cu subsLane cumarlnlce,
c)lnfecll cu Lscherlchla coll,
o)vasoollaLall lnouse oe meolcamenLe (fenoLlazlne),
e)hemoragll.
6. SLenoza aorLlc sau pulmonar poaLe lnouce:
a);oc hlpovolemlc,
b);oc carologen,
c);oc enooLoxlnlc,
o);oc neurogenlc,
e);oc anafllacLlc.
7. lnfarcLul mlocarolc lnouce sLare oe ;oc, consecuLlv:
a)colapsulul hlpovolemlc,
b)colapsulul carologen, prln lnsuflclen coronarlan,
c)oeprlmrll acLlvlLll meLabollce oxloaLlve,
o)ellberrll unel canLlLl crescuLe oe hlsLamln,
e)hlpercaLecolamlnemlel.
8. CasLroenLerlLa acuL (olareea), poaLe lnouce sLare oe ;oc prln:
a)oeperolle hlorlc, pleroerl maslve oe elecLrolll ;l vasoollaLale,
b)colaps carologen, prln lnsuflclen coronarlan,
c)oeprlmarea acLlvlLll meLabollce oxloaLlve,
o)ellberarea unel canLlLl crescuLe oe hormonl corLlcosLerolzl,
e)hlpercaLecolamlnemle.
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9. erlLonlLa lnouce sLare oe ;oc prln:
a)oeprlmarea acLlvlLll meLabollce oxloaLlve,
b)colaps carologen, prln lnsuflclen coronarlan,
c)oeprlmarea acLlvlLll meLabollce oxloaLlve,
o)vasoollaLale in LerlLorlul splahnlc ;l pleroerl oe ap ;l elecLrolll,
e)hlpercaLecolamlnemle.
10. Care olnLre urmLoarele evenlmenLe nu lnouce pleroerl absoluLe oe flulo sanguln,
cl pleroerl relaLlve, prln cre;Lerea paLulul vascular?
a)hemoragla exLern,
b)anafllaxla,
c)plasmoragla,
o)hlororagla ;l elecLrollLoragla,
e)hemoragla lnLern.
11. 5ocul hlpovolemlc poaLe fl lnous prln olmlnuarea volumulul sanguln clrculanL cu
clrca:
a)10,
b)20,
c)2S,
o)30
e)S0.
12. Pemoragllle lnouse oe alLerarea funclonallLll vasculare sau a facLorllor
coagulrll, lnLr in caLegorla:
a)hemoraglllor chlrurglcale,
b)hemoraglllor exogene,
c)hemoraglllor enoogene nexLerrlorlzaLe,
o)hemoraglllor meolcale,
e)hemoraglllor enoogene exLerlorlzaLe.
13. PemaLemeza ;l meLroragla lnLr in caLegorla:
a)hemoraglllor lnLersLllale,
b)hemoraglllor exogene,
c)hemoraglllor enoogene neexLerlorlzaLe,
o)hemoraglllor meolcale,
e)hemoraglllor enoogene exLerlorlzaLe.
14. Pemoragllle seroase ;l lnLersLllale lnLr in caLegorla:
a)hemoraglllor lnLersLllale,
b)hemoraglllor exogene,
c)hemoraglllor enoogene neexLerlorlzaLe,
o)hemoraglllor meolcale,
e)hemoraglllor enoogene exLerlorlzaLe.
1S. Care olnLre urmLoarele cauze nu lnLr in caLegorla celor care poL genera ;oc
hlpoxemlc, in conolllle in care sngele clrcul normal, oar nu esLe oxlgenaL
corecL?
a)Lumorlle pulmonare,
b)pneumoLoraxul,
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c)hemoragllle,
o)lezlunlle cenLrllor resplraLorl,
e)anesLezla oe lung ouraL.
16. 5oculul prln rlolcarea garoulul apare incepno oln momenLul in care inoeprLarea
compreslel genereaz:
a)punerea in clrculale a meLabollllor Loxlcl, elaboral in esuLurlle lschemlaLe,
b)scoerea brusc a preslunll arLerlale,
c)olmlnuarea bruLal a volemlel,
o)olmlnuarea frecvenel ;l forel oe conLracle a lnlmll,
e);oc neurogen.
17. Care olnLre urmLoarele efecLe nu fac parLe olnLre aclunlle proLecLoare in sLrlle
oe ;oc, speclflce CL
1
;l CL
2
?
a)impleolcarea formrll facLorulul mlocaroo-Loxlc,
b)impleolcarea formrll facLorulul oepresor al slsLemulul reLlculo-enooLellal,
c)relaxarea sflncLerelor posLcapllare,
o)mrlrea sLablllLll membranelor llzozomlce,
e)oepresla acLlvlLll carolace.
18. laza oe reacle neurovegeLaLlv, oln caorul reaclel flzlologlce la agreslune,
consL in punerea in funclune a:
a)slsLemulul paraslmpaLlc,
b)slsLemulul renln-angloLensln-aloosLeron,
c)slsLemulul orLoslmpaLlc,
o)mecanlsmelor umorale cu efecL anabollc,
e)slLemulul oe reglare a olurezel.
19. laza oe reacle neuroenoocrln, oln caorul reaclel flzlologlce la agreslune,
rezulL oln aclunea:
a)caLecolamlnelor ;l corLlcosLerolzllor,
b)slsLemulul paraslmpaLlc,
c)S1P-ulul,
o)mecanlsmelor umorale cu efecL anabollc,
e)slLemulul LermoregulaLor.
20. LfecLele glucocorLlcolzllor se concreLlzeaz ;l prln:
a)sLlmularea anabollsmulul proLelnelor ;l llploelor,
b)sLlmularea meLabollsmulul bazal,
c)sLlmularea caLabollsmulul Llsular, al proLelnelor ;l llploelor,
o)aclune prolnflamaLoare,
e)sLlmularea Lermogenezel.
21. 1lmpul anabollc al reaclel flzlologlce la agreslune, esLe marcaL, prlnLre alLele ;l oe
ellberarea oe:
a)S1P,
b)caLecolamlne,
c)glucagon,
o)hormonl Llrololenl,
e)hormonl glucocorLlcolzl.
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S
22. 8eacla paLologlc la agreslune oebuLeaz prln:
a)ellberarea exceslv sau perslsLenL oe corLlcosLerolzl ;l aparlla raplo oe
cercurl vlcloase auLo-agreslve,
b)ellberarea exceslv sau perslsLenL oe caLecolamlne ;l aparlla raplo oe cercurl
vlcloase auLo-agreslve,
c)olmlnuarea exceslv a screlel oe corLlcosLerolzl ;l aparlla raplo oe cercurl
vlcloase auLo-agreslve,
o)olmlnuarea exceslv a screlel oe corLlcosLerolzl ;l aparlla raplo oe cercurl
vlcloase auLo-agreslve,
e)olmlnuarea exceslv a screlel oe corLlcosLerolzl fr aparlla raplo oe cercurl
vlcloase auLo-agreslve,
23. lasmexoola, efecL manlfesLaL pe parcursul sLrllor oe ;oc, esLe cauzaL oe:
a)hlpoLenslunea arLerlal,
b)olureza crescuL,
c)cre;Lerea permeablllLll capllare,
o)cre;Lerea vlLezel oe curgere a sngelul,
e)lnsuflclena coronan.
24. Care olnLre urmLoarele manlfesLrl paLologlce nu lnouce prln lmpllcallle sale
plasmexoole?
a)ocluzla lnLesLlnal,
b)arsurlle,
c)slnoromul oe compreslune,
o)oeshloraLrlle,
e)hemoragla.
2S. PlsLamlna, lmpllcaL in generarea ;oculul, are efecLe:
a)vasoconsLrlcLor ;l hlperpermeablllzanL la nlvel capllar,
b)vasoollaLaLor ;l hlperpermeablllzanL la nlvel capllar,
c)vasoconsLrlcLor ;l hlpopermeablllzanL la nlvel capllar,
o)hlpopermeablllzanL la nlvel capllar, fr s lmpllce reacll vasomoLorll,
e)hlperpermeablllzanL, fr s lmpllce reacll vasomoLorll.
26. ln Llmpul reaclel paLologlce la agreslune, orl oe cLe orl acloneaz un agenL
eLlologlc asupra organlsmulul, lmeolaL lnLr in funclune mecanlsmele prln care se
reallzeaz:
a)vasoconsLrlcle perlferlc ;l splanchnlc, precum ;l vasoollaLale la nlvelul
crelerulul ;l mlocaroulul,
b)vasoconsLrlcle perlferlc, splanchnlc, coronarlan ;l cerebral,
c)vasoollaLale perlferlc, splanchnlc, coronarlan ;l cerebral,
o)vasoollaLale perlferlc ;l splanchnlc, precum ;l vasoconsLrlcle coronarlan ;l
cerebral,
e)vasoollaLale perlferlc ;l coronarlan.
27. SeroLonlna, lmpllcaL in generarea ;oculul, acloneaz prln:
a)vasoconsLrlcle ;l sLaz la nlvelul vaselor mlcl,
b)vasoollaLale ;l ampllflcarea oeblLulul sanguln la nlvelul vaselor mlcl,
c)vasoconsLrlcle ;l ampllflcarea oeblLulul sanguln la nlvelul vaselor mlcl,
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o)vasoconsLrlcle generallzaL ;l ampllflcarea oeblLulul sanguln la nlvelul vaselor
mlcl,
e)vasoollaLale ;l sLaz la nlvelul vaselor mlcl.
28. Care olnLre urmLoarele evenlmenLe nu face parLe olnLre conseclnele
lnLenslflcrll acloozel, consecuLlve ;oculul:
a)scoerea Lonusulul vascular,
b)olmlnuarea ranoamenLulul acLlvlLll carolace
c)conLracla sflncLerelor precapllare.
o)favorlzarea agluLlnrll elemenLelor flguraLe ale sngelul (sluoge-ul),
e)favorlzeaz formarea oe mlcroLrombl.
29. klnlnele plasmaLlce, consLanL inLilnlLe in sLrlle oe ;oc, au efecLe:
a)vasoollaLaLoare ;l hlperLenslve,
b)vasoconsLrlcLoare ;l hlpoLenslve,
c)vasoollaLaLoare ;l hlpoLenslve,
o)vasoconsLrlcLoare ;l hlperLenslve,
e)hlpoLenslve, fr s anLreneze efecLe vasomoLorll.
30. Care olnLre urmLoarele evenlmenLe nu esLe lnous oe lnLrarea enooLoxlnelor
bacLerlene in clrculala sanguln, evenlmenL consecuLlv unor sLrl oe ;oc?
a)acLlvarea cascaoel complemenLulul,
b)sLlmularea elaborrll monoamlnoblogenelor (MA8),
c)agregarea ;l agluLlnarea placheLar,
o)agravarea procesulul oe coagulare lnLravascular (Clu),
e)vasoconsLrlcle la nlvelul mlcroclrculalel.
31. 1ermenul oe poollng oesemneaz o manlfesLare speclflc fazelor avansaLe ale
;oculul, care consL in:
a)sechesLrarea ;l sLagnarea fluloulul sanguln in secLorul mlcroclrculalel,
b)olmlnuarea oeblLulul sanguln in secLorul mlcroclrculalel,
c)exLravazarea fazel plasmaLlce a sngelul,
o)cre;Lerea volemlel,
e)acumularea sngelul in cavlLlle naLurale.
32. Aclooza, consecuLlv fazelor avansaLe ale ;oculul, esLe cauzaL oe:
a)vasoollaLala cuLanaL,
b)vasoconsLrlcla cuLanaL,
c)scoerea vlLezel oe clrculalel a sngelul,
o)scoerll frecvenel resplraLorll,
e)comuLarea gllcollzel aerobe spre cea anaerob.
33. La nlvelul mlcroclrculalel, in prlma faz a aclunll facLorllor ;ocogenl, se
manlfesL:
a)vasoconsLrlcle arLerlolo-meLaarLerlolo-capllaro-venular, cu oeschloerea
shunLurllor arLerlolo-venulare olrecLe,
b)vasoollaLale arLerlolar ;l vasoconsLrlcle venular,
c)vasoollaLale venular ;l vasoconsLrlcle areLrlolar,
o)inchloerea shunLurllor arLerlolo-venulare olrecLe,
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e)vasoollaLale generallzaL.
34. 8spunsul carolac la ellberarea caLecolamlnelor, consecuLlv fazelor lnllale ale
;oculul, esLe caracLerlzaL prln rspuns:
a)cronoLrop ;l lnoLrop negaLlv,
b)cronoLrop ;l lnoLrop pozlLlv,
c)cronoLrop negaLlv ;l lnoLrop pozlLlv,
o)cronoLrop pozlLlv ;l lnoLrop negaLlv,
e)cronoLrop negaLlv, funcla lnoLrop nefllno afecLaL.
3S. 1erenul oe sluoge oesemneaz o manlfesLare speclflc fazelor avansaLe ale
;oculul, care consL in:
a)coagularea sngelul, la nlvelul mlcroclrculalel,
b)hemollza, la nlvelul mlcroclrculalel,
c)flbrlnollza, la nlvelul mlcroclrculalel,
o)agregarea celulelor sangulne (placheLar ;l erlLroclLar), la nlvelul
mlcroclrculalel,
e)coagularea sngelul, la nlvel slsLemlc.
36. Care olnLre urmLorll facLorl nu se incaoreaz in caLegorla acelora, care sunL
lmpllcal in generarea vasoollaLalel ;l hlpoLonlel capllare, oe pe parcursul sLrllor
oe ;oc?
a)hlpoxla,
b)aclooza,
c)MA8,
o)klnlnele plasmaLlce,
e)caLecolamlnele.
37. Plpovolemla acloneaz la nlvelul rlnlchlulul, prln:
a)olmlnuarea ulLrafllLrrll glomerulare,
b)accenLuarea olurezel,
c)lnhlbarea slsLemulul renln-angloLensln-aloosLeron,
o)olmlnuarea reabsorblel Lubulare a apel,
e)olmlnuarea reabsorblel Lubulare a soolulul.
38. ln fazele lnllale ale ;oculul, urmare a aclunll caLecolamlnelor, la nlvelul flcaLulul
are loc:
a)sLlmularea gllcogenollzel ;l lnoucerea hlpergllcemlel,
b)lnhlbarea gllcogenollzel ;l lnoucerea oe hlpogllcemlel,
c)lnhlbarea neoglucogenezel ;l lnoucerea oe hlpogllcemle,
o)sLlmularea neoglucogenezel ;l lnoucerea oe hlpogllcemle,
e)lnhlbarea gllcogenollzel ;l sLlmularea neoglucogenezel.
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8
39. La lnsLalarea eoemulul pulmonar, compllcale la nlvel oe organ a ;oculul,
parLlclp:
a)cre;Lerea slnLezel oe surfacLanL ;l lnLenslflcarea alLerrll perellor capllarelor
pulmonare,
b)scoerea slnLezel oe surfacLanL ;l olmlnuarea alLerrll perellor capllarelor
pulmonare,
c)cre;Lerea slnLezel oe surfacLanL ;l olmlnuarea alLerrll perellor capllarelor
pulmonare,
o)olmlnuarea slnLezel oe surfacLanL ;l lnLenslflcarea alLerrll perellor capllarelor
pulmonare,
e)olmlnuarea alLerrll perellor capllarelor pulmonare, fr a fl afecLaL nlvelul
secrelel oe surfacLanL.
40. rlnLre organele afecLaLe oe ;oc se numr ;l pancreasul, care in conolll oe
lschemle ellbereaz un:
a)facLor sLlmulaLor al mlocaroulul, cu efecL lnoLrop negaLlv,
b)facLor oepresor al mlocaroulul, cu efecL lnoLrop negaLlv,
c)facLor oepresor al mlocaroulul, cu efecL lnoLrop pozlLlv,
o)facLor sLlmulaLor al mlocaroulul, cu efecL lnoLrop pozlLlv,
e)facLor sLlmulaLor carolac, cu efecL cronoLrop negaLlv.
41. Care olnLre urmLoarele semne cllnlce nu face parLe olnLre cele speclflce LuLuror
formelor oe ;oc, cu excepla celul sepLlc?
a)mucoase congesLlonaLe,
b)Lahlcarole,
c)puls perlferlc slab,
o)frecven resplraLorle crescuL,
e)hlpoLermle.
42. Care olnLre urmLoarele manlfesLrl nu esLe caracLerlsLlc ;oculul sepLlc, in faza
sa hlperolnamlc?
a)Lahlcarole,
b)mucoase aparenLe ro;ll crmlzll,
c)frecven resplraLorle crescuL,
o)pollurle,
e)febr.
43. Care olnLre urmLoarele manlfesLrl nu esLe caracLerlsLlc ;oculul sepLlc, in faza
sa hlpoolnamlc?
a)pollurle,
b)Lahlcarole sau braolcarole,
c)mucoase aparenLe palloe,
o)frecven resplraLorle crescuL,
e)hlpoLermle.
44. Care olnLre urmLoarele conseclne nu esLe cauzaL oe hlpoxla Llsualar, speclflc
;oculul?
a)ollaLala ;l hlpoLonla capllar,
b)comuLarea gllcollzel pe calea anaerob,
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9
c)olsfuncll celulare,
o)necrobloz,
e)vasoconsLrlcle la nlvelul mlcroclrculalel.
4S. Care olnLre urmLoarele evenlmenLe nu fac parLe olnLre cele lnouse oe acLlvarea
slmpaLo-aorenerglc, speclflc fazelor Llmpurll ale ;oculul?
a)cre;Lerea frecvenel ;l forel oe conLracle a lnlmll,
b)vasoconsLrlcle perlferlc,
c)hlpogllcemle.
o)conLracle splenlc,
e)gllcogenollz.
46. ln conolllle gllcollzel anaerobe, proces oaLoraL hlpoxlel consecuLlve ;oculul, olnLr-
un mol oe glucoz rezulL:
a)38 moll oe A1,
b)30 moll oe A1,
c)2S moll oe A1,
o)12 moll oe A1,
e)2 moll oe A1.
47. e parcursul sLrllor oe ;oc, parameLrll meLabollsmul proLelnelor manlfesL
moolflcrl in sensul:
a)cre;Lerll nlvelulul proLelnelor plasmaLlce ;l cel al amlnacloemlel,
b)scoerll nlvelulul proLelnelor plasmaLlce ;l cel al amlnacloemlel,
c)cre;Lerll nlvelulul proLelnelor plasmaLlce ;l scoerll celul al amlnacloemlel,
o)scoerll nlvelulul proLelnelor plasmaLlce ;l cre;Lerll celul al amlnacloemlel,
e)cre;Lerll nlvelulul proLelnelor plasmaLlce, amlnacloemla nefllno afecLaL.
48. e parcursul sLrllor oe ;oc, parameLrll meLabollsmul llploelor manlfesL
moolflcrl in sensul:
a)cre;Lerll nlvelulul llploelor plasmaLlce ;l cel al corpllor ceLonlcl,
b)scoerll nlvelulul llploelor plasmaLlce ;l cel al corpllor ceLonlcl,
c)cre;Lerll nlvelulul llploelor plasmaLlce ;l scoerea celul al corpllor ceLonlcl,
o)scoerll nlvelulul llploelor plasmaLlce ;l cre;Lerll celul al corpllor ceLonlcl,
e)scoerll nlvelulul llploelor plasmaLlce ;l neafecLarea nlvelulul corpllor ceLonlcl.
49. AfecLarea funclonal a pompel Na
+
/k
+
- A1-aza, consecuLlv fazelor avansaLe ale
;oculul, oeLermln:
a)cre;Lerea concenLralel celulare a Na
+
;l k
+
,
b)scoerea concenLralel celulare a Na
+
;l k
+
,
c)cre;Lerea concenLralel celulare a Na
+
;l a celel lnLersLllale a k
+
,
o)scoerea concenLralel celulare a Na
+
;l a celel lnLersLllale a k
+
,
e)cre;Lerea concenLralel celulare a Na
+
;l scoerea celel lnLersLllale a k
+
.
S0. Acumularea lnLracelular a Na
+
, consecuLlv fazelor avansaLe ale ;oculul,
oeLermln:
a)hlpernaLremle,
b)hlponaLremle,
c)oeshloraLare celular,
o)oegenerescena hloroplc a celulel,
1\/^1) I1 1(1)I/ - ^1I1(1)/ (1I1)1)/)/ 2J1
10
e) afecLarea funclonal a pompel Na
+
/k
+
- A1-aza.
S1. ulmlnuarea olsponlbllulul oe A1, consecuLlv fazelor avansaLe ale ;oculul,
oeLermln:
a)cre;Lerea concenLralel celulare a Ca
+
;l k
+
,
b)scoerea concenLralel celulare a Ca
+
;l k
+
,
c)cre;Lerea concenLralel celulare a Ca
+
;l a celel lnLersLllale a k
+
,
o)scoerea concenLralel celulare a Ca
+
;l a celel lnLersLllale a k
+
,
e)cre;Lerea concenLralel celulare a Ca
+
;l scoerea celel lnLersLllale a k
+
.
S2. Care olnLre urmLorll facLorl nu lnLr in caLegorla poLenlalllor agenl plrogenl
exogenl?
a)bacLerllle Cram negaLlve,
b)complexele Ag-AC,
c)Loxlcele oln caLegorla barblLurlcelor,
o)proLelnele heLerospeclflce absorblLe oln lnLesLln,
e)subsLanele cu provenlen nelnfecloas, elaboraLe oe esuLurl necrozaLe,
neoplazlce.
S3. Care olnLre urmLoarele subsLane nu se lmpllc in paLogenla reaclel febrlle?
a)lnLerferonll,
b)facLorul oe necroz Lumoral,
c)lnLerleuklna 1 (lL-1),
o)hlsLamlna,
e) lnLerleuklna 2 (lL-2),
S4. Care olnLre urmLoarele Llpurl celulare nu face parLe olnLre cele lmpllcaLe in
slnLeza plrogenllor enoogenl?
a)monoclL,
b)macrofag perlLoneal,
c)celula kupffer,
o)eozlnofll,
e)neuLrofll.
SS. Care olnLre urmLoarele parLlcularlLl nu caracLerlzeaz plrogenll enoogenl?
a)neolallzablll,
b)Lermolablll,
c)sunL lnacLlval oe enzlme proLeollLlce,
o)au sLrucLur llpoproLelc,
e)au mas molecular cuprlns inLre S0.000 ;l 100.000.
S6. lrogenll enoogenl acloneaz la nlvelul:
a)reelel vasculare a hlpoLalamusulul anLerlor (CvL1), unoe sLlmuleaz
prooucerea oe gL,
b)reelel vasculare a hlpoLalamusulul posLerlor (CvL1), unoe lnhlb prooucerea
oe gL,
c)reelel vasculare a hlpoLalamusulul anLerlor (CvL1), unoe sLlmuleaz
prooucerea oe gl,
o)reelel vasculare a hlpoLalamusulul posLerlor (CvL1), unoe lnhb prooucerea oe
gl,
1\/^1) I1 1(1)I/ - ^1I1(1)/ (1I1)1)/)/ 2J1
11
e)reelel vasculare a hlpoLalamusulul anLerlor (CvL1), unoe sLlmuleaz
prooucerea oe caLecolamlne.
S7. Aclunea anLlfebrll a asplrlnel se manlfesL prln:
a)lnhlblla ellberrll oe C,
b)blocarea formrll plrogenulul enoogen oe cLre leucoclLe,
c)lnhlbarea cenLrulul hlpoLalamlc LermogeneLlc,
o)sLlmularea cenLrulul hlpoLalamlc LermollLlc,
e)lnhlbarea lL-1.
S8. ln cursul lnsLlLulrll reaclel febrlle, prosLaglanolnele gL acloneaz la nlvelul:
a)hlpoLalamusulul anLerlor, unoe acesLea oeLermln un nou echlllbru Lermlc, la un
nlvel mal rlolcaL,
b)hlpoLalamusulul anLerlor, unoe acesLea oeLermln un nou echlllbru Lermlc, la
un nlvel mal sczuL,
c)hlpoLalamusulul posLerlor, unoe acesLea oeLermln un nou echlllbru Lermlc, la
un nlvel mal rlolcaL,
o)hlpoLalamusulul posLerlor, unoe acesLea oeLermln un nou echlllbru Lermlc, la
un nlvel mal sczuL,
e)hlpoflzel anLerloare, unoe acesLea oeLermln un nou echlllbru Lermlc, la un
nlvel mal rlolcaL.
S9. Care olnLre urmLoarele manlfesLrl nu esLe caracLerlsLlc reaclel febrlle?
a)frlsonul Lermlc,
b)pollpneea Lermlc,
c)hlpersuoorala (Lransplrala),
o)lnLenslflcarea secrelllor Llrololene ;l suprarenallene,
e)vasoollaLala cuLanaL.
60. SLaolul lncremenLl a reaclel febrlle se manlfesL, in speclal prln:
a)menlnerea LemperaLurll corporale la un nlvel crescuL ;l manlfesLarea frlsonulul
Lermlc,
b)scoerea LemperaLurll corporale ;l manlfesLarea frlsonulul Lermlc,
c)cre;Lerea LemperaLurll corporale ;l manlfesLarea frlsonulul Lermlc,
c)menlnerea LemperaLurll corporale la un nlvel sczuL,
e)menlnerea LemperaLurll corporale la un nlvel crescuL ;l menlnerea frlsonulul
Lermlc.
61. Conform Legll lul van'L Poff, cre;Lerea LemperaLurll corporale cu 1
o
C, oeLermln
ampllflcarea meLabollsmulul bazal cu:
a)0,
b)3,
c)13,
o)19,
e)21
1\/^1) I1 1(1)I/ - ^1I1(1)/ (1I1)1)/)/ 2J1
12
62. e parcursul sLaolulul lncremenLl al reaclel febrlle, raplolLaLea cre;Lerll
LemperaLurll corporale ;l lnLenslLaLea frlsonulul Lermlc se gsesc:
a)inLr-o relale oe lnvers proporlonallLaLe,
b)inLr-o relale oe olrecL proporlonallLaLe,
c)inLr-o relale lnoepenoenL (necorelaL),
o)inLr-o relale oe lnhlbare reclproc,
e)frlsonul nu caracLerlzeaz sLaolulul lncremenLl al reaclel febrlle.
63. SLaolul fasLlgll al reaclel febrlle se manlfesL, in speclal prln:
a)menlnerea LemperaLurll corporale la un nlvel crescuL, prln sLablllrea unul nou
nlvel oe echlllbru inLre Lermogenez ;l Lermollz,
b)scoerea LemperaLurll corporale ;l sLablllrea unul nou nlvel oe echlllbru inLre
Lermogenez ;l Lermollz,
c)cre;Lerea LemperaLurll corporale ;l manlfesLarea frlsonulul Lermlc,
o)cre;Lerea LemperaLurll corporale ;l sLablllrea unul nou nlvel oe echlllbru inLre
Lermogenez ;l Lermollz,
e)menlnerea LemperaLurll corporale la un nlvel crescuL, prln sLablllrea unel
prevalene a Lermollzel asupra Lermogenezel.
64. lebra acuL are o ouraL meole oe:
a)1-2 zlle,
b)S-6 zlle,
c)10 zlle,
o)10-30 oe zlle,
e)mal marl oe 30 oe zlle.
6S. lebra subacuL are o ouraL meole oe:
a)1-2 zlle,
b)S-6 zlle,
c)10 zlle,
o)10-30 oe zlle,
e)mal marl oe 30 oe zlle.
66. lebra efemer are o ouraL meole oe:
a)1-2 zlle,
b)S-6 zlle,
c)10 zlle,
o)10-30 oe zlle,
e)mal marl oe 30 oe zlle.
67. lebra conLlnu se manlfesL prln:
a)oscllall olurne oe pn la S
o
C,
b)oscllall olurne oe pn la 4
o
C,
c)oscllall olurne oe pn la 3
o
C,
o)oscllall olurne oe pn la 2
o
C,
3)oscllall olurne oe pn la 1
o
C.
1\/^1) I1 1(1)I/ - ^1I1(1)/ (1I1)1)/)/ 2J1
13
68. Curba Lermlc in Lrapez esLe caracLerlsLlc:
a)febrel conLlnue,
b)febrel olsconLlnue,
c)febrel acuLe,
o)febrel cronlce,
e)febrel subacuLe.
69. Curba Lermlc in orepLunghl esLe caracLerlsLlc:
a)febrel conLlnue,
b)febrel olsconLlnue,
c)febrel acuLe,
o)febrel cronlce,
e)febrel subacuLe.
70. Curba Lermlc in clopoL esLe caracLerlsLlc:
a)febrel conLlnue,
b)febrel olsconLlnue,
c)febrel acuLe,
o)febrel cronlce,
e)febrel subacuLe.
71. Curba Lermlc in febr recurenL esLe caracLerlsLlc:
a)febrel conLlnue,
b)febrel olsconLlnue,
c)febrel acuLe,
o)febrel cronlce,
e)febrel subacuLe.
72. Curba Lermlc in febr remlLenL esLe caracLerlsLlc:
a)febrel conLlnue,
b)febrel olsconLlnue,
c)febrel acuLe,
o)febrel cronlce,
e)febrel subacuLe.
73. Curba Lermlc in febr lnLermlLenL esLe caracLerlsLlc:
a)febrel conLlnue,
b)febrel olsconLlnue,
c)febrel acuLe,
o)febrel cronlce,
e)febrel subacuLe.
74. Curba Lermlc in febr onoulanL esLe caracLerlsLlc:
a)febrel conLlnue,
b)febrel olsconLlnue,
c)febrel acuLe,
o)febrel cronlce,
e)febrel subacuLe.
1\/^1) I1 1(1)I/ - ^1I1(1)/ (1I1)1)/)/ 2J1
14
7S. Lvolula febrll caracLerlzaL oe perloaoe febrlle lungl (S-8 zlle), care alLerneaz cu
perloaoe subfebrlle egale, esLe caracLerlsLlc:
a)curbel Lermlce in febr recurenL,
b)curbel Lermlce in febr remlLenL,
c)curbel Lermlce in febr lnLermlLenL,
o)curbel Lermlce in febr onoulanL,
e)curbel Lermlce in clopoL.
76. Lvolula febrll caracLerlzaL oe perloaoe febrlle lungl (S-8 zlle), care alLerneaz cu
perloaoe afebrlle varlablle, esLe caracLerlsLlc:
a)curbel Lermlce in febr recurenL,
b)curbel Lermlce in febr remlLenL,
c)curbel Lermlce in febr lnLermlLenL,
o)curbel Lermlce in febr onoulanL,
e)curbel Lermlce in clopoL.
77. Lvolula febrll caracLerlzaL oe un plaLou, cu oscllall olurne mal marl oe 1
o
C,
esLe caracLerlsLlc:
a)curbel Lermlce in febr recurenL,
b)curbel Lermlce in febr remlLenL,
c)curbel Lermlce in febr lnLermlLenL,
o)curbel Lermlce in febr onoulanL,
e)curbel Lermlce in clopoL.
78. Lvolula febrll caracLerlzaL oe o alLernan regulaL a unor puseurl febrlle oe
scurL ouraL (paroxlsme), cu perloaoe afebrlle (aplrexle) oe ouraLe varlablle, esLe
caracLerlsLlc:
a)curbel Lermlce in febr recurenL,
b)curbel Lermlce in febr remlLenL,
c)curbel Lermlce in febr lnLermlLenL,
o)curbel Lermlce in febr onoulanL,
e)curbel Lermlce in clopoL.
79. SLaolul oecremenLll a reaclel febrlle se manlfesL, in speclal prln:
a)menlnerea LemperaLurll corporale la un nlvel crescuL, prln sLablllrea unul nou
nlvel oe echlllbru inLre Lermogenez ;l Lermollz,
b)scoerea LemperaLurll corporale, prln sLablllrea unel prevalene a Lermollzel
asupra Lermogenezel,
c)cre;Lerea LemperaLurll corporale ;l manlfesLarea frlsonulul Lermlc,
o)cre;Lerea LemperaLurll corporale ;l sLablllrea unul nou nlvel oe echlllbru inLre
Lermogenez ;l Lermollz,
e)menlnerea LemperaLurll corporale la un nlvel crescuL, prln sLablllrea unel
prevalene a Lermollzel asupra Lermogenezel.
80. uefervescena Lermlc oerulaL prln crlz:
a)se proouce in 1-2 zlle, nefllno oe bun augur penLru organlsm,
b)se proouce in 1-2 zlle, fllno oe bun augur penLru organlsm,
c)se proouce in mal mulLe zlle, fllno oe bun augur penLru organlsm,
o)se proouce in mal mulLe zlle, nefllno oe bun augur penLru organlsm,
1\/^1) I1 1(1)I/ - ^1I1(1)/ (1I1)1)/)/ 2J1
1S
e)se proouce in mal mulLe zlle, nelnfluenno prognosLlcul evolulel.
81. uefervescena Lermlc oerulaL prln lysls:
a)se proouce in 1-2 zlle, nefllno oe bun augur penLru organlsm,
b)se proouce in 1-2 zlle, fllno oe bun augur penLru organlsm,
c)se proouce in mal mulLe zlle,
o)se proouce in mal mulLe zlle, nefllno oe bun augur penLru organlsm,
e)se proouce in 1-2 zlle, nelnfluenno prognosLlcul evolulel.
82. Care olnLre urmLoarele manlfesLrl nu esLe speclflc orLoslmapLlcoLonlel, sLare
caracLerlsLlc fazelor lnllale ale reaclel febrlle?
a)Lahlcarole,
b)hlperpnee,
c)mlorlaz,
o)scoerea secrelllor olgesLlve,
e)vasoollaLale cuLanaL.
83. lrecvena carolac, in Llmpul reaclel febrlle, esLe:
a)olrecL proporlonal cu ascenslunea Lermlc ;l cre;Le cu 2-6 bLl/mlnuL penLru
flecare
o
C,
b)olrecL proporlonal cu ascenslunea Lermlc ;l cre;Le cu 8-10 bLl/mlnuL
penLru flecare
o
C,
c)lnvers proporlonal cu ascenslunea Lermlc ;l scaoe cu 2-6 bLl/mlnuL penLru
flecare
o
C,
o)lnvers proporlonal cu ascenslunea Lermlc ;l scaoe cu 8-10 bLl/mlnuL
penLru flecare
o
C,
e)lnoepenoenL oe evolula Lermlc.
84. Ml;crlle resplraLorll, in Llmpul reaclel febrlle, sunL:
a)acceleraLe ;l profunoe,
b)rrlLe ;l superflclale,
c)acceleraLe ;l superflclale,
o)rrlLe ;l profunoe,
e)varlablle oln puncL oe veoere al frecvenel ;l ampllLuolne.
8S. AcLlvlLaLea Lubulul olgesLlv, in Llmpul reaclel febrlle, se manlfesL prln:
a)hlpersecrele gasLrolnLesLlnal ;l hlperperlsLalLlsm lnLesLlnal,
b)hlposecrele gasLrolnLesLlnal ;l hlperperlsLalLlsm lnLesLlnal,
c)hlposecrele gasLrolnLesLlnal ;l hlpoperlsLalLlsm lnLesLlnal,
o)hlpersecrele gasLrolnLesLlnal ;l hlpoperlsLalLlsm lnLesLlnal,
e)normosecrele gasLrolnLesLlnal ;l normoperlsLalLlsm lnLesLlnal.
86. ln perloaoa oe oefervescen, Lransplrala consLlLule un mecanlsm eflclenL oe
scoere a LemperaLurll corporale, pleroerea a 1,6 l oe ap lnoucno ellmlnarea a:
a)100 kcal,
b)300 kcal,
c)S00 kcal,
1\/^1) I1 1(1)I/ - ^1I1(1)/ (1I1)1)/)/ 2J1
16
o)900 kcal,
e)1000kcal.
87. uaLorlL reoucerll aporLulul oe glucloe ;l secrelel oe caLecolamlne, evenlmenLe
consecuLlve reaclel febrlle, la nlvelul meLabollsmulul gluclolc se remarc:
a)scoerea gllcogenollzel hepaLlce ;l musculare, uneorl inreglsLrnou-se
hlpogllcemle,
b)cre;Lerea gllcogenollzel hepaLlce ;l musculare, uneorl inreglsLrnou-se
hlpogllcemle,
c)scoerea gllcogenollzel hepaLlce ;l musculare, uneorl inreglsLrnou-se
hlpergllcemle,
o)cre;Lerea gllcogenollzel hepaLlce ;l musculare, uneorl inreglsLrnou-se
hlpergllcemle,
e)scoerea gllcogenollzel hepaLlce ;l musculare, fr s fle afecLaL gllcemla.
88. Care olnLre urmLoarele reacll flzlologlce ;l comporLamenLale ale organlsmulul
nu face parLe olnLre cele lmpllcaLe in conservarea clourll corporale, speclflc
sLaolulul lncremenLl, al reaclel febrlle?
a)braolpnee,
b)plloerecle,
c)pozlle ghemulL,
o)vasoconsLrlcle,
e)moolflcarea comporLamenLulul prln cuLarea unul loc calo.
89. Care olnLre urmLoarele reacll ale organlsmulul nu face parLe olnLre cele
lmpllcaLe in generarea clourll corporale, speclflc sLaolulul lncremenLl, al reaclel
febrlle?
a)frlson,
b)lnLenslflcarea caLabollsmulul llplolc,
c)lnLenslflcarea caLabollsmulul gluclolc,
o)lnLenslflcarea caLabollsmulul proLelnelor,
e)vasoollaLale perlferlc.
90. ColesLerolemla are un nlvel:
a)crescuL in sLaolul lncremenLl,
b)crescuL in sLaolul fasLlgll,
c)sczuL in sLaolul oecremenLl,
o)crescuL in perloaoa oe convalescen,
e)normal in sLaollle lncremenLl ;l fasLlgll.
91. e parcursul reacll febrlle, parameLrll meLabollsmul llploelor manlfesL moolflcrl
in sensul:
a)meLabollzrll llploelor oe rezerv ;l a cre;Lerll nlvelulul corpllor ceLonlcl in
snge,
b)olmlnurll llpollzel ;l a scoerll nlvelulul corpllor ceLonlcl in snge,
c)lnLenslflcrll llpollzel ;l scoerll nlvelulul corpllor ceLonlcl in snge,
1\/^1) I1 1(1)I/ - ^1I1(1)/ (1I1)1)/)/ 2J1
17
o)olmlnurll llpollzel ;l cre;Lerll nlvelulul corpllor ceLonlcl in snge,
e)olmlnurll llpollzel ;l neafecLarea nlvelulul corpllor ceLonlcl oln snge.
92. e parcursul reacll febrlle, parameLrll meLabollsmul proLelnelor manlfesL
moolflcrl in sensul:
a)lnLenslflcrll anabollsmulul proLelnelor ;l olmlnurll azoLulul ellmlnaL prln urln,
b)lnLenslflcrll anabollsmulul proLelnelor ;l ampllflcrll azoLulul ellmlnaL prln
urln,
c)lnLenslflcrll caLabollsmulul proLelnelor ;l olmlnurll azoLulul ellmlnaL prln urln,
o)lnLenslflcrll caLabollsmulul proLelnelor ;l ampllflcrll azoLulul ellmlnaL prln
urln,
e)lnLenslflcrll caLabollsmulul proLelnelor ;l neafecLrll azoLulul ellmlnaL prln
urln.
93. e parcursul reaclel febrlle, coLa oe parLlclpare a proLelnelor la meLabollsmul
energeLlc esLe oe:
a)S,
b)10,
c)1S,
o)2S,
e)pesLe 30.
94. e parcursul prlmelor sLaoll ale reaclel febrlle, are loc cre;Lerea marcanL a
vlLezel oe SeolmenLare a PemaLlllor, ca urmare a:
a)cre;Lerll nlvelulul sanguln al albumlnelor plasmaLlce,
b)cre;Lerll nlvelulul sanguln al facLorllor plasmaLlcl al coagulrll sangulne,
c)scoerll nlvelulul sanguln al facLorllor plasmaLlcl al coagulrll sangulne,
o)cre;Lerll nlvelulul sanguln al alfa ;l gama-globullnelor,
e)scoerll nlvelulul sanguln al alfa ;l gama-globullnelor.
9S. e parcursul prlmelor sLaoll ale reaclel febrlle, are loc cre;Lerea a coagulablllLll
sangulne, ca urmare a:
a)cre;Lerll nlvelulul sanguln al albumlnelor ;l globullnelor,
b)cre;Lerll nlvelulul sanguln al flbrlnogenulul, proaccelerlnel ;l proconverLlnel,
c)scoerll nlvelulul sanguln al flbrlnogenulul, proaccelerlnel ;l proconverLlnel,
o)cre;Lerll nlvelulul sanguln al llploelor plasmaLlce,
e)scoerll nlvelulul sanguln al albumlnelor, globullnelor ;l flbrlnogenulul.
96. ln sLrlle febrlle cronlce, prlnLre alLele, se consLaL:
a)scoerea proLelnemlel ;l a preslunll osmoLlce a plasmel sangulne,
b)cre;Lerea proLelnemlel ;l scoerea preslunll osmoLlce a plasmel sangulne,
c)scoerea proLelnemlel ;l cre;Lerea preslunll osmoLlce a plasmel sangulne,
o)cre;Lerea proLelnemlel ;l a preslunll osmoLlce a plasmel sangulne,
e)scoerea proLelnemlel ;l neafecLarea preslunll osmoLlce a plasmel sangulne,
1\/^1) I1 1(1)I/ - ^1I1(1)/ (1I1)1)/)/ 2J1
18
97. Care olnLre urmLoarele manlfesLrl nu esLe caracLerlsLlc sLaollor lncremenLl ;l
fasLlgll ale reaclel febrlle?
a)lnLenslflcarea olurezel,
b)relnerea clorurllor,
c)hemoconcenLrale,
o)lnLenslflcarea caLabollsmulul proLelc,
e)relnerea apel.
98. Care olnLre urmLoarele manlfesLrl nu esLe caracLerlsLlc sLaolulul oecremenLl al
reaclel febrlle?
a)lnLenslflcarea olurezel,
b)ellmlnarea clorurllor,
c)mloz,
o)lnLenslflcarea anabollsmulul,
e)Lahlcarole ;l Lahlpnee.
99. Sub raporL energo-olnamlc, reacla febrll:
a)moolflc raporLul olnLre energla blologlc uLll (L
bu
) ;l energla olslpaL
LermogeneLlc (L
1g-o
) in favoarea ulLlmel,
b)nu moolflc raporLul olnLre energla blologlc uLll (L
bu
) ;l energla olslpaL
LermogeneLlc (L
1g-o
),
c)moolflc raporLul olnLre energla blologlc uLll (L
bu
) ;l energla olslpaL
LermogeneLlc (L
1g-o
) in favoarea celel olnLl,
o)cre;Le valoarea energlel blologlc uLll (L
bu
) ;l a celel olslpaLe LermogeneLlce (L
1g-
o
),
e)scaoe valoarea energlel blologlc uLll (L
bu
) ;l a celel olslpaLe LermogeneLlce (L
1g-
o
).
100. ln febra posLenooLoxlnlc, se remarc oe regul o reacle leucoclLar blfazlc,
caracLerlzaL:
a)lnllal prlnLr-o ampllflcarea a numrulul pollmorfonucleaLelor ;l urmaL apol oe
leucopenle,
b)lnllal prlnLr-o olmlnuare a pollmorfonucleaLelor ;l urmaL apol oe leucoclLoz,
c)lnllal prlnLr-o ampllflcarea a numrulul mononucleaLelor ;l urmaL apol oe
leucopenle,
o)lnllal prlnLr-o ampllflcarea a numrulul mononucleaLelor ;l urmaL apol oe
leucoclLoz,
e)lnllal prlnLr-o ampllflcarea a numrulul eozlnofllelor ;l urmaL apol oe
eozlnopenle.
1|tu|ar d|sc|p||n,
Conf. dr. Gabr|e| Cotor