Adrenogenital syndrome

Etiology - Caused by partial or complete failure, one or more enzymes required for the synthesis of steroids. - Genetically inherited in an autosomal recessive

 Pathophysiology - C-20 Deficiency hidrosilase Is the most severe type and is equivalent kelaianan early steroid synthesis Baby boy failed to produce intrauterine testosterone. Eventually overrun by the adrenal glands, causing cholesterol hipeplasia adrenal lipids. In the event of severe biochemical disturbances will cause death

 Deficiency C-3 Beta dehydrogenase Affect the gonads so cortisol is reduced so that the increased secretion of corticosteroids. Terajadi consequently lead to salt retention and hypertension. had no menstruation In the female external genitalia tap pesudohermaprodite In men

 C-21 hydroxylase deficiency Most commonly occurs due to deficiency of which causes excess cortisol andorgen. heavy state spending on Natriium after birth and fatal normal external genitalia > Baby boy rapid growth Baby female genitalia

 C-11 Deficiency A hidrosilase The disorder occurs in the last step synthesis of cortisone and aldosterone. Cortisol in the blood to normal shingga increased androgen deosikortikosteron. yng cause virilization and hipertension

Insufisiency adrenocortical
Acute adrenocortical insufficiency Etiology and pathology - Absolute or relative deficiency of cortisol that occurs suddenly is usually caused by illness or severe stress. - Because the bacterial toxin in severe infections bilateral adrenal hemorrhage due to multiple in all parts of the bodyOn meningococcal septicemia mainly by bleeding

Caused by stress, mild infections, in patients where decreased adrenal response, for whatever reason or disruption due to damage to the pituitary release of ACTH or corticosteroid and ACTH therapy is used common cause widely

 Chronic adrenocortical insufficiency

EPIDEMIOLOGY Found in the middle of the last usie land perlhana berthun for months even years with no specific complaints.

ETIOLOGY AND PATHOLOGY

Caused by kegaga; corticosteroids am working. more importantly asalah gluko and mineralocorticoid deficiency with symptoms is unclear. Aldosterone failure tends to cause loss of sodium and potassium retention and a decrease in blood glucose.

Pigmentation occurs due to excretion melonocyte stimulating hormone (MSH) excessive ACTH secretion is accompanied by an increase in plasma levels of low krotisol Another cause is tuberculosis but more often idiotpatik Very rarely caused by secondary neoplasms and granulomas