critical appraisal form for single therapy studies

Is the research valid? 1a. Was the assignment of patients to treatments randomised? 1b. Was the randomisation list concealed?

Comments

YES NO

1c. Were subjects and clinicians blind to which treatment was being received? Comments 2a. Were all subjects who entered the trial accounted for at its conclusion? 2b. Were they analysed in the groups to which they were randomised? 3a. Aside from the experimental treatment, were the groups treated equally? 3b. Were the groups similar at the start of the trial?

YES NO

Comments

YES NO

Is the research important? RRR (Relative risk

reduction)

ARR (Absolute risk

reduction)

NNT (Number
needed to treat)

CER (Control event EER (Experimental

rate) event rate)

CER-EER/CER

CER-EER

1/ARR

Can I apply it to my patient? 4. Is this patient so different from those in the trial that the results dont apply?

Comments

YES

NO
Comments

5a. How great would the benefit of therapy be for this particular patient? 5b. What is the event rate in my practice for patients like this one? (PEER - Patient expected event rate)

Is it consistent with the patients values and preferences? 6. Do I have a clear assessment of the patients values and preferences?

Comments

YES

NO
Comments

7. Do this intervention and its potential consequences meet them?

YES NO

Clinical bottom-line