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Outline 12 1. Salivary secretion A. Function B. Secretory mechanism i.

i. Rate = neural control via para (Ach) and sym (NoE) ii. Muscarinic receptor antag: decrease/agonist: increase iii. Low rates: reabsort ( low NaCl, nigh K and HCO3-) iv. Aldosterone modifies electrolyte []; not rate C. Regulation of secretion D. Effect of flow rate 2. Gastric acid secretion A. Function B. Secretory mechanism i. HCl PIG, HisGaS, BM ii. HCl = HAG/ProstgSS (PPI/H2 receptor antagonist) C. Regulation of secretion 1. Gastrin a. Increase:PsGAGrp/D:S 2. Histamine a. GPS3. Somatostatin a. Inhibit! D. Inter-regulation of acid secretion

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