INVESTIGATION OF ANAEMIA

Max F J Mantik Sub Bagian Hematologi-Onkologi Bagin Ilmu Kesehatan Anak FK Unsrat / RSUP Manado

Anaemia : Diagnosis
Following information required: Age Anamnesis Physical examination Haemoglobin estimate Above will make diagnosis likely in 95% of patients

Important anamnestic data:

Sudden / slow onset of pallor Constitutional symptoms - Weight - Night sweats Underlying disease - Peptic Ulcer ? - Liver disease ? - Nutritional deficiency ?

Physical examination

Pallor ( Not detectable unless Hb Jaundice ( icterus) Petechiae, bruising Hepatomegaly Splenomegaly Significant lymphadenopathy

8 gr% )

Haemoglobin estimate
Done on machine: (do not trust unless machine standardized) Machine requires: calibration and standardization Costly automated machines are not essential for acurate haemoglobin measurements

Stained blood film provides data on :

Significant RBC Changes Adequacy of thrombocytes Estimate of WBC count ( 500) Abnormality of leucocytes

Anaemia can be classified (inspect blood smear)

Microcytic, hypochromic Normocytic, normochromic Macrocytic Mixture of above