Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1994;12(2):147-9.

[Studies on the efficacy of albendazole candy for treatment of intestinal nematode infections].
[Article in Chinese] Gan Y1, Wu Q, Ou F, Li G, Huang J, Wei Q, Nong C, Nong L. Author information

Abstract
A single dose of albendazole (candy) 100 mg and 100 mg qd for two days was given respectively to 135 and 321 children who were infected with Enterobius vermicularis. All cases were cured 3wk later according to perianal tape examination. The same drug of 150 mg qd and 200 mg qd for two days was administered respectively to residents with single or multi-infections of Ascaris, hookworm and Trichuris; the egg negative conversion rates of the two dosages were revealed to be 99.4% (466/469) and 99.8% (487/488) for Ascaris infection, 96.8% (91/94) and 94.3% (99/105) for hookworm infection, and 53.4% (228/427) and 76.3% (370/486) for Trichuris infection. The maximal numbers of worm expelled were 100 on d2-3, 88 on d3-5 and 588 on d2-4 for Enterobius, Ascaris and hookworm, respectively; whereas the discharged Trichuris were scarce, merely 4.3 in average. The results exhibited promising efficacy of the drug on Enterobius, Ascaris and hookworm infections, but not so on trichuriasis.
PMID: 7955168 [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Clinical Trial Controlled Clinical Trial English Abstract MeSH Terms

Albendazole/administration & dosage* Animals Ascariasis/drug therapy Child Child, Preschool Enterobiasis/drug therapy Humans Intestinal Diseases, Parasitic/drug therapy* Nematode Infections/drug therapy* Parasite Egg Count Trichuriasis/drug therapy Substances

Albendazole