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Preeclampsia, a Disease of the Maternal Endothelium

by Camille E. Powe, Richard J. Levine, and S. Ananth Karumanchi

Circulation Volume 123(24):2856-2869 June 21, 2011

Copyright American Heart Association, Inc. All rights reserved.

Abnormal placentation in preeclampsia.

Powe C et al. Circulation 2011;123:2856-2869

Copyright American Heart Association, Inc. All rights reserved.

sFlt1 and soluble endoglin (sEng) cause endothelial dysfunction by antagonizing vascular endothelial growth factor (VEGF) and transforming growth factor-1 (TGF-1) signaling.

Powe C et al. Circulation 2011;123:2856-2869

Copyright American Heart Association, Inc. All rights reserved.

Summary of the pathogenesis of preeclampsia.

Powe C et al. Circulation 2011;123:2856-2869

Copyright American Heart Association, Inc. All rights reserved.

Model for pregnancy as a stress test for long-term cardiovascular disease.

Powe C et al. Circulation 2011;123:2856-2869

Copyright American Heart Association, Inc. All rights reserved.

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