The Hazardous 100+ List of Chemicals of High Concern Hazardous 100 List (Last updated: 7/17/13)

Chemical Name CASRN Chemical Acronym or Synonym Authoritative Lists (see key below)* WASHINGTON CALIFORNIA MINNESOTA EU REACH

www.saferchemicals.org
Reference for Toxicity Information (see key below) 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 3 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

US EPA

MAINE

Primary Type of Toxicity

Primary Category

2-Aminotoluene 2-Naphthylamine 3,3'-Dimethylbenzidine* 4,4'-Bis(dimethylamino)benzophenone 4,4'-Methylenedi-o-toluidine 4-Aminoazobenzene 6-Methoxy-m-toluidine Benzenamine Benzidine and its salts Benzidine-based and benzidine congener-based dyes (Azo dyes)* C.I. Solvent Yellow 14 C.I. Solvent Yellow 3 N,N,N',N'-tetramethyl-4,4'methylenedianiline Hexabromocyclododecane* Polybrominated diphenyl ethers* Tetrabromobisphenol A Tris(2-chloroethyl) phosphate 1,1,2,2-Tetrachloroethane 1-Bromopropane Methylene chloride Perchloroethylene Trichloroethylene Furan Antimony trioxide* Arsenic & arsenic compounds* Beryllium & beryllium compounds* Cadmium & cadmium compounds* Chromium & chromium compounds* Cobalt & cobalt compounds Lead & lead compounds* Mercury & mercury compounds*

95-53-4 91-59-8 119-93-7 90-94-8 838-88-0 60-09-3 120-71-8 62-53-3 92-87-5 Various 842-07-9 97-56-3 101-61-1 25637-99-4 Various 79-94-7 115-96-8 79-34-5 106-94-5 75-09-2 127-18-4 79-01-6 110-00-9 1309-64-4 7440-38-2 7440-41-7 7440-43-9 7440-47-3 7440-48-4 7439-92-1 7439-97-6

o-Toluidine o-Tolidine Michler's ketone Aniline yellow p-Cresidine Aniline

x x x x x x x x x x

x x

x x x

C C C C x x x x C C x x x x x x x x x x x x x C C x x x x x x x C C x x x x x A x C A C

cancer cancer cancer cancer cancer cancer cancer cancer cancer cancer cancer cancer cancer PBT PBT; vPvB PBT cancer cancer developmental cancer cancer cancer cancer cancer cancer cancer cancer cancer, developmental cancer cancer developmental

Dyes & Pigments Dyes & Pigments Dyes & Pigments Dyes & Pigments Dyes & Pigments Dyes & Pigments Dyes & Pigments Dyes & Pigments Dyes & Pigments Dyes & Pigments Dyes & Pigments Dyes & Pigments Dyes & Pigments Halogenated Flame Retardants Halogenated Flame Retardants Halogenated Flame Retardants Halogenated Flame Retardants Halogenated Solvents Halogenated Solvents Halogenated Solvents Halogenated Solvents Halogenated Solvents Various Uses Metals Metals Metals Metals Metals Metals Metals Metals

Sudan I o-Aminoazotoluene Michler's base HBCD PBDEs TBBPA TCEP

x x x

x x n-Propyl bromide (nPB) x x PCE or Perc x TCE x x x x x x x x x x

*Additional information on specific listings marked with an asterisk is available upon request

The Hazardous 100+ List of Chemicals of High Concern Hazardous 100 List (Last updated: 7/17/13)
Chemical Name CASRN Chemical Acronym or Synonym Authoritative Lists (see key below)* WASHINGTON CALIFORNIA MINNESOTA EU REACH

www.saferchemicals.org
Reference for Toxicity Information (see key below) 1 1 1 1 4 2 1 5 (a) 1 6 6 1 1 1 1 1 1 1 3, 6, 7 1 1 1 5 (b) 6 1 1 1 1 4 1 4

US EPA

MAINE

Primary Type of Toxicity

Primary Category

Nickel & nickel compounds* Benzyl butyl phthalate Di-(2-ethylhexyl) phthalate Dibutyl phthalate Diethyl phthalate Diisobutyl phthalate Diisodecyl phthalate* Diisononyl phthalate* Di-n-hexyl phthalate Di-n-octyl phthalate Di-n-pentyl phthalate 1,3-Butadiene 2,4-Diaminotoluene 2,4-Dinitrotoluene 4,4-Methylenebis(2-Chloroaniline) 4,4-Diaminodiphenylmethane 4,4'-Oxydianiline Acrylonitrile Bisphenol A Epichlorohydrin Ethylbenzene Propylene oxide Styrene Toluene diisocyanate* Triglycidyl isocyanurate Vinyl chloride 1,3-Dimethylol-5,5-dimethylhydantoin 2-Bromo-2-nitropropane-1,3-diol Butyl paraben Butylated hydroxyanisole Ethyl paraben

7440-02-0 85-68-7 117-81-7 84-74-2 84-66-2 84-69-5 26761-40-0 28553-12-0 84-75-3 117-84-0 131-18-0 106-99-0 95-80-7 121-14-2 101-14-4 101-77-9 101-80-4 107-13-1 80-05-7 106-89-8 100-41-4 75-56-9 100-42-5 26471-62-5 2451-62-9 75-01-4 6440-58-0 52-51-7 94-26-8 25013-16-5 120-47-8

BBP DEHP DBP DEP DIBP DIDP DINP DnHP DnOP DnPP

x x x x

x x x x x

x x x

x x x x x x x x

x A x A x A x A x x x x C C A C A C x

DNT MBOCA MDA

x x x x x x x x x x x x x

x x x

BPA ECH PPO

x x

x x x

C x x x C x x

TDI
TGIC VC or VCM DMDM hydantoin Bronopol BHA

x x x

x x x

cancer developmental cancer developmental endocrine disruption (Cat 1) reproductive (Cat 1B) developmental developmental developmental developmental developmental cancer cancer cancer cancer cancer cancer cancer endocrine disruption cancer cancer cancer cancer (reasonably anticipated) dermal and inhalation sensitization developmental cancer cancer (based on formaldehyde) cancer (based on formaldehyde) endocrine disruption (Cat 1) cancer endocrine disruption (Cat 1)

Metals Phthalates Phthalates Phthalates Phthalates Phthalates Phthalates Phthalates Phthalates Phthalates Phthalates Plastics Building Blocks Plastics Building Blocks Plastics Building Blocks Plastics Building Blocks Plastics Building Blocks Plastics Building Blocks Plastics Building Blocks Plastics Building Blocks Plastics Building Blocks Plastics Building Blocks Plastics Building Blocks Plastics Building Blocks Plastics Building Blocks Plastics Building Blocks Plastics Building Blocks Preservatives & Antimicrobials Preservatives & Antimicrobials Preservatives & Antimicrobials Preservatives & Antimicrobials Preservatives & Antimicrobials

*Additional information on specific listings marked with an asterisk is available upon request

The Hazardous 100+ List of Chemicals of High Concern Hazardous 100 List (Last updated: 7/17/13)
Chemical Name CASRN Chemical Acronym or Synonym Authoritative Lists (see key below)* WASHINGTON CALIFORNIA MINNESOTA EU REACH

www.saferchemicals.org
Reference for Toxicity Information (see key below) 4 4 1 4 1 1 1 1 1 1 4 2 2 4 4 4 4 6 1 1 1 1 1 1 1 1 1 1 1 1 1

US EPA

MAINE

Primary Type of Toxicity

Primary Category

Methyl paraben Propyl paraben Quaternium-15 Octamethylcyclotetrasiloxane 2-Ethoxyethyl acetate Ethylene glycol monoethyl ether Ethylene glycol monomethyl ether N,N-dimethylacetamide N-Methylpyrrolidone Toluene 4-n-Octylphenol 4-tert-Octylphenol Nonylphenol, ethoxylated* p-Nonylphenol* Benzophenone-2 Octyl methoxycinnamate Perfluorooctanesulfonic acid & salts* Perfluorooctanoic acid & its salts* 1,2,3-Trichloropropane 1,2-Dibromoethane; Ethylene dibromide 1,2-Dichloroethane; Ethylene dichloride 1,4-Dioxane 2-Ethylhexanoic acid 2-Methoxyaniline Acetaldehyde Acrylamide Benzene Biphenyl-4-ylamine Carbon disulfide Diethyl sulphate Dimethyl sulphate

99-76-3 94-13-3 4080-31-3 556-67-2 111-15-9 110-80-5 109-86-4 127-19-5 872-50-4 108-88-3 1806-26-4 140-66-9 9016-45-9 104-40-5 131-55-5 5466-77-3 1763-23-1 335-67-1 96-18-4 106-93-4 107-06-2 123-91-1 149-57-5 90-04-0 75-07-0 79-06-1 71-43-2 92-67-1 75-15-0 64-67-5 77-78-1 EDB EDC D4 EGEE EGME DMA NMP x x x x x x

x x

x x

x x x x x x x x x x x C C C C C

tOP NPE NP BP-2 Octinoxate PFOS

x x x x x x x x

C x C x

x x C

endocrine disruption (Cat 1) endocrine disruption (Cat 1) cancer (based on formaldehyde) endocrine disruption (Cat 1) developmental developmental developmental developmental developmental developmental endocrine disruption (Cat 1) endocrine disruption endocrine disruption endocrine disruption (Cat 1) endocrine disruption (Cat 1) endocrine disruption (Cat 1) reproductive (Cat 1B) reproductive and developmental cancer cancer

Preservatives & Antimicrobials Preservatives & Antimicrobials Preservatives & Antimicrobials Siloxanes Solvents Solvents Solvents Solvents Solvents Solvents Surfactants Surfactants Surfactants Surfactants Ultraviolet (UV) Light Absorbers Ultraviolet (UV) Light Absorbers Perfluorinated Chemicals (PFCs) Perfluorinated Chemicals (PFCs) Various Uses Various Uses Various Uses Various Uses Various Uses Various Uses Various Uses Various Uses Various Uses Various Uses Various Uses Various Uses Various Uses

PFOA
x x x x x x x x x x x x x x x x

cancer cancer developmental cancer cancer cancer cancer cancer developmental cancer cancer

o-Anisidine

C x C x x C x C C

*Additional information on specific listings marked with an asterisk is available upon request

The Hazardous 100+ List of Chemicals of High Concern Hazardous 100 List (Last updated: 7/17/13)
Chemical Name CASRN Chemical Acronym or Synonym Authoritative Lists (see key below)* WASHINGTON CALIFORNIA MINNESOTA EU REACH

www.saferchemicals.org
Reference for Toxicity Information (see key below) 1 1 1 1 1 1 1 4 1 4 2

US EPA

MAINE

Primary Type of Toxicity

Primary Category

Estragole Formaldehyde Hexachlorobutadiene Hydrazine* N-Nitrosodimethylamine N-Nitrosodiphenylamine p-Chloroaniline Pentachlorobenzene Phenolphthalein p-Hydroxybenzoic acid Short chain chlorinated paraffins*

140-67-0 50-00-0 87-68-3 302-01-2 62-75-9 86-30-6 106-47-8 608-93-5 77-09-8 99-96-7 85535-84-8

HCBD NDMA

x x x x x x x x

x x

x x x C x x x x C x x C

x pHBA SCCPs x

cancer cancer cancer cancer cancer cancer cancer endocrine disruption (Cat 1) cancer endocrine disruption (Cat 1) PBT; vPvB

Various Uses Various Uses Various Uses Various Uses Various Uses Various Uses Various Uses Various Uses Various Uses Various Uses Various Uses

*Additional information on specific listings marked with an asterisk is available upon request

The Hazardous 100+ List of Chemicals of High Concern Additional chemicals of high concern
(Last updated: 7/17/13)
Authoritative Lists (see key below)* WASHINGTON CALIFORNIA MINNESOTA

www.saferchemicals.org
Reference for Toxicity Information (see key below) 8 9 9 1 10 1 2 2 1

Chemical Name

CASRN

Chemical Acronym or Synonym

EU REACH

US EPA

MAINE

Primary Type of Toxicity

Primary Category

Tris(1-chloro-2-propyl) phosphate* 2-Ethylhexyl-2,3,4,5tetrabromobenzoate Bis(2-ethylhexyl)-3,4,5,6tetrabromophthalate Tris(1,3-Dichloro-2-propyl) phosphate Tris(1,3-dichloropropyl) phosphate* Tris(2,3-dibromopropyl) phosphate Dibutyltin dichloride Tributyltin oxide Triphenyltin hydroxide

13674-84-5 183658-27-7 26040-51-7 13674-87-8 40120-74-9 126-72-7 683-18-1 56-35-9 76-87-9

TCPP

carcinogen developmental; acute and chronic aquatic developmental; acute and chronic aquatic cancer probable human carcinogen cancer reproductive (Cat 1B) PBT cancer anticipated: - reproductive (based on DBTC); - PBT (based on TBTO); - cancer (based on TPTH)

Halogenated Flame Retardants Halogenated Flame Retardants Halogenated Flame Retardants Halogenated Flame Retardants Halogenated Flame Retardants Halogenated Flame Retardants Organotins Organotins Organotins

TBB TBPH TDCPP TBP DBTC TBTO TPTH

x x C C x

Other organotins*

Various

1,2

Organotins

Perfluorohexane sulfonic acid & its salts* Perfluorohexanoic acid Bisphenol S Methylenediphenyl diisocyanate & related compounds* Triclosan Decamethylcyclopentasiloxane

355-46-4 307-24-4 80-09-1 26447-40-5 3380-34-5 541-02-6

PFHxS PFHxA BPS MDI

reproductive and developmental reproductive and developmental endocrine disruption (based on BPA)

6 6 3,6,7 6 11 4

Perfluorinated Chemicals (PFCs) Perfluorinated Chemicals (PFCs) Plastics Building Blocks Plastics Building Blocks Preservatives & Antimicrobials Siloxanes

dermal and inhalation sensitization endocrine disruption; potential antibiotic resistance

D5

endocrine disruption (Cat 1) (based on D4)

*Additional information on specific listings marked with an asterisk is available upon request

The Hazardous 100+ List of Chemicals of High Concern

Key for Authoritative Lists CALIFORNIA: State of California "List of Chemicals Known to Cause Cancer or Reproductive Toxicity" (Proposition 65 list) MAINE: State of Maine "Designated Priority Chemicals" "List of Chemicals of High Concern" MINNESOTA: State of Minnesota "List of Priority Chemicals" WASHINGTON: State of Washington "List of Chemicals of High Concern to Children" US EPA: United States Environmental Protection Agency "Existing Chemicals Action Plans" EU REACH: European Union: "Authorisation List" (A) "Candidate List of Substances of Very High Concern for Authorisation" (C) References for Toxicity Information 1: State of California "List of Chemicals Known to Cause Cancer or Reproductive Toxicity" (Proposition 65 List) 2: European Union: "Authorisation List" (A) and "Candidate List of Substances of Very High Concern for Authorisation" (C) 3: State of Washington "List of Chemicals of High Concern to Children" 4: European Commission Endocrine Disruptor Website 5 (a): National Toxicology Program Monograph on the Potential Human Reproductive and Developmental Effects of DINP (2003) 5 (b): National Toxicology Program 12th Report on Carcinogens 6: United States Environmental Protection Agency "Existing Chemicals Action Plans" 7: State of Maine "Designated Priority Chemicals" 8: California EPA, Office of Environmental Health Hazard Assessment (OEHHA) 9: United States Envronmental Protection Agency "TSCA Work Plan Chemicals" 10: United States Consumer Product Safety Commission (US CPSC) 11: Published literature Key for Acronyms CASRN: Chemical Abstracts Service Registry Number PBT: Persistent, bioaccumulative and toxic vPvB: Very persistent and very bioaccumulative

*Additional information on specific listings marked with an asterisk is available upon request