DR. NAITIK D.

TRIVEDI,
LECTURER,
A. R. COLLEGE OF PHARMACY & G. H. PATEL
INSTITUTE OF PHARMACY, VALLABH VIDYANAGAR,
ANAND, GUJARAT
E-mail: mastermindnaitik@gmail.com
OBJECTIVES OF EPERIMENTAL
PHARMACOLOGICAL EXPERIMENTS
DR. UPAMA N. TRIVEDI,
ASSISTANT PROFESSOR,
SHIVAM PHARMACEUTICAL STUDIES & RESEARCH CENTRE,
VALASAN , ANAND, GUJARAT
E-mail: ups.aasthu@gmail.com
PHARMACOLOGICAL EXPERIMENTS
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OBJECTIVES OF EPERIMENTAL PHARMACOLOGICAL EXPERIMENTS
To screen drug substance for their biological activities.
To study the toxicity of drugs.
To study mechanismof action and site of action of the drug.
EXPERIMENTAL PHARMACOLOGY INVOLVES:
Preclinical Experiments: Which consist of animal studies for deciding the
safety, efficacy, pharmacokinetics and pharmacodynamics of a new drug or a safety, efficacy, pharmacokinetics and pharmacodynamics of a new drug or a
newdrugformulation.
Clinical Experiments: These follow preclinical studies. In clinical
pharmacology, efficacy, safety, and pharmacokinetics of a drug substance is
determined through its use in healthy human volunteers and patient
populations under controlled conditions. Only those drugs which are found
safe and effective in preclinical (animal) studies are further investigated in
suchstudies.
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