Professional Documents
Culture Documents
Short Essay For The Skin (A&P)
Short Essay For The Skin (A&P)
Merocrine glands:
-Synthesized on ribosomes attached to rough ER
-Processed, sorted, packaged by Golgi Complex
-released from cell by secretory vesicles
Apocrine glands:
-accumulate secretory product at apical surface of secreting cell
-that portion pinches off from rest of cell to release secretion
-remaining part repairs itself and repeats process
Holocrine glands:
-Accumulate secretory product in cytosol
-as secretory cell matures it ruptures, becomes secretory product
-sloughed off cell replaced by new cell
Epidermal:
1. Basal cells enlarge, migrate across wound until advancing cells from opposite ends
meet
2. Epidermal growth factor stimulate basal stem cells to divide, replace cells that have
moved into wound
3. Replacement continued until wound resurfaced
4. Relocated cells divide to build new strata, thickening epidermis
Inflammatory phase:
1.Blood clot forms in wound, unites wound edges, inflammation
A. Vasodilation and increased capillary permeability enhance delivery of repair cells:
neutrophils, monocytes, menchymal cells
Migratory phase:
1. clot becomes scab, epithelial cells migrate beneath scab to bridge wound
2. Fibroblasts synthesize scar tissue
3. Damaged blood vessels begin to regrow
Proliferative stage:
1. Extensive growth of epithelial cells beneath scab, fibroblasts produce collagen fibers,
continued growth of blood vessels
Maturation phase:
1. Scab sloughs off once epidermis restored
2. Collagen fibers organized, fibroblasts increase, blood vessels return to normal