By the end of March Chapter 1: Introduction, literature search and aims By the end of April Chapter 2: Methodology By the end of April Chapter 3-1: Normal values for our HRIM device used in this study By the end of May Chapter 3-2: Stimulation tests the effect on healthy subjects (establishing normal values) By the end of May Chapter 4: Stimulation tests relevance of test results with symptoms of patients with OH By the end of June Chapter 5: Proximal oesophageal hypomotility: clinical significance and effect of stimulation tests By the end of June Chapter 6: Effect of AZY on OH and the impact of AZY- therapy on dysphagia and GORD symptoms By the end of July Chapter 7: Predictive value of stimulation test in the response to AZY treatment By the end of July Chapter 8: Conclusion and future studies By the end of August Final revisions, printing and submission By 20 th of September