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Name of Drug Classification Mechanism of Action Indication

Generic name: donepezil


Trade /Brand
name: Aricept,
Patients dose:

Maximum dose:10mg

Minimum dose:5mg

Contents: none

Availability:5mg.10mg

Route of administration:po

Source :drug guide for
nurses p470
Pharmacologic class:
cholinergic

Therapeutic:
anti-Alzheimers agents
Pregnancy risk category:C

Source: drug guide for
nurses p470
Chemical: Inhibits acetyl
cholinesterase thus improving
cholinergic function by making
more acetylcholine available.

Therapeutic: may temporarily
lessen some of the dementia
associated with Alzheimer
disease.

Pharmacokinetics:
Onset: unknown
Peak: several week
Duration: 6 week
Drug half-life: 70hr

Source: drug guide for nurses
p470
General indication: Mild to moderate dementia
associated with Alzheimers disease.

Patients indication:

Source: drug guide for nurses p470

Contraindication Side effects Nursing Responsibilities
Contraindication:
Hypersensitivity to donepezil
or piperidine derivatives.

Precautions: patient with
underlying cardiac disease.

Drug interactions: Exaggerates
muscle relaxation from
succinylcholine.

Source: drug guide for nurses
p470
, fatigue, dizziness, nausea,
vomiting, diarrhea, loss of
appetite, weight loss,
Source:
Before: Assess cognitive function periodically during therapy.

During: Disturbed thought process

After: Improvement in cognitive function in patient with Alzheimers
disease.

Source: drug guide for nurses p470
Adverse effect

Seizures, fainting, abnormal heart
beats, and stomach ulcers also may
occur


Source: drug guide for nurses p470

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