1

beclomethasone
synthetic glucocorticoid that readily penetrates the
airway mucosa, used for asthma
thioridazine
low potency dopamine receptor
blocker
thioridazine
side effects are retinal deposits, torsades, postural
hypotension, sedation, CNS depression
valproic acid
causes neural tube defects
valproic acid
used to treat all kinds of seizures, as well as bipolar
disorder
2
zolpidem
binds benzodiazepine receptors,
antagonized by flumazenil
zolpidem
hypnotic drug that is not a
benzodiazepine
amphetamines
indirect sympathomimetic MOA
cocaine
inhibits catecholamine reuptake, resulting in
cardiotox and hypertension
disulfiram
inhibits aldehyde dehydrogenase, causing an
accumulation of acetaldehyde
3
flunitrazepam
benzodiazepine used as a date rape
drug
lysergic acid diethylamide hallucinogenic, nausea, weakness
mescaline
hallucinogenic, nausea, weakness
psilocybin
hallucinogenic, nausea, weakness
marijuana
lowers intraocular pressure in
glaucoma
4
methadone
treatment of opiod withdrawal
opioid withdrawal syndrome
nausea, chills, sweats, lacrimation, cramps,
rhinorrhea, yawning, piloerection, diarrhea, tremor
MPTP
destroys dopaminergic neurons of
the nigrostriatal tract
morphine
binds mu receptors
enkephalin
binds delta receptors
5
dynorphins
bind kappa receptors
opioid overdose
constricted pupils, clammy skin, nausea, drowsiness,
resp depression
phencyclidine (pcp)
nystagmus, hypertension, seizure
acetaminophen
COX inhibitor which inhibits
prostaglandin synthesis
acetaminophen
analgesic, antipyretic (but not
anti-inflammatory)
6
allopurinol
suicide inhibition of xanthine
oxidase
allopurinol
increases xanthine and hypoxanthine, which are less
likely to form crystals than uric acid
allopurinol
slows production of uric acid, used to treat gout (and
cancer)
aspirin PGE inhibitor
aspirin
predisposes to acute gastritis by inhibiting PGE in
the stomach
7
aspirin
irreversible inhibitor of
cyclooxygenase
aspirin
analgesic, antipyretic, antiplatelet,
anti-inflammatory
capsaicin
impairs release of substance P
capsaicin
used topically for RA
celecoxib
COX-2 inhibitor
8
rofecoxib
COX-2 inhibitor
celecoxib sulfa drug
rofecoxib sulfa drug
colchicine
inhibits microtubule assembly, and therefore
leukocyte migration and phagocytosis
colchicine
leukocyte inhibitor used to treat attacks of gouty
arthritis
9
cyclosporin
binds to cyclophilins and inhibits the transcription of
cytokine genes
tacrolimus
binds to the immunophilin
FK-binding protein
cyclosporin
impairs T cell IL-2 production, used
in transplant patients
tacrolimus
used in transplant patients
etanercept
a fusion product of TNF-alpha receptor and Fc
portion of antibody
10
infliximab
binds and inhibits TNF-alpha
etanercept
used in RA and inflammatory bowel
disease
gold salts nephrotoxic
gold salts used in RA
gold salts
decreases lysosomal and
macrophage function
11
ibuprofen
similar to aspirin, lacks antiplatelet
effects
ibuprofen
reversibly inhibits COX
indomethacin
potent NSAID used to close a PDA
PGE
used to maintain a PDA in
congenital heart disease
ketorolac
parenteral NSAID
12
meperidine
causes relaxation of the sphincter of
oddi
meperidine
causes increased ICP
opiods
causes biliary spasm
sumatriptan
binds the serotonin 1D receptor
sumatriptan
causes vasoconstriction of cerebral
vasculature
13
sumatriptan
used for acute migraine and cluster
headaches
thalidomide
used to treat SLE, multiple
myeloma, and leprosy
thalidomide
suppresses production of TNF-alpha
thalidomide
potent
immunosuppressant
statins
may cause elevated liver enzymes
14
statins
may cause myositis
statins
may cause increased CK from
skeletal muscle
reserpine
enters the CNS and may cause suicidal depression
and parkinsonian symptoms
reserpine
antihypertensive agent that blocks the storage and
release of catecholamines and serotonin from
neurons
probucol
decreases HDL as well as LDL
15
probucol
prevents restenosis after angioplasty
probucol
acts as an antioxidant
nitroglycerin
postural hypotension, headache,
flushing
nitroglycerin
causes increase in cGMP in vascular
smooth muscle
niacin
directly reduces secretion of VLDLs
16
niacin increases HDL
niacin
causes cutaneous flushing
vincristine
M phase inhibitor
vincristine
blocks microtubule polymerization
and spindle formation
ABVD
adriamycin, bleomycin, vinblastine,
dacarbazine
17
MOPP
mechlorethamine, oncovin,
procarbazine, prednisone
vincristine
used for lymphomas, wilms tumor,
and choriocarinomas
heparin activates AT3
heparin
inactivates thrombin
protamine sulfate
reverses effects of heparin
18
trastuzumab
binds to receptor tyrosine kinase
Erb-B2 (HER-2)
trastuzumab
used for HER-2 positive breast
cancer
tamoxifen
estrogen receptor partial antagonist
tamoxifen
increases risk of endometrial
carcinoma
rituximab
binds CD20 antigen on B cells
19
rituximab
treatment of non-hodgkin
lymphoma
prednisone
triggers apoptosis
prednisone
treatment for leukemia, lymphoma,
RA, asthma
paclitaxel
prevents mitotic spindle breakdown
paclitaxel
interferes with
anaphase
20
paclitaxel
microtubule stabilizing agent
methotrexate
S phase inhibitor
methotrexate inhibits DHFR
leucovorin
treats
myelosuppression
methotrexate
folic acid analog
21
mercaptopurine
(6-MP)
activated by hypoxanthine-guanine
phosphoribosyltransferase (HGPRT)
mercaptopurine
(6-MP)
inhibits many enzymes involved in
purine metabolism
leuprolide
treatment for endometriosis
leuprolide
treatment for BPH and precocious
puberty
leuprolide
stimulates release of FSH and LH
22
leuprolide
GnRH agonist used to treat prostate
cancer
interferon alpha
produced by virally infected cells to prevent infection
of adjacent cells
interferon alpha
used to treat CML, malignant myeloma, kaposi
sarcoma, hairy cell leukemia
interferon alpha
recombinantly produced cytokine
flutamide
used to antagonize residual
androgens after orchiectomy
23
flutamide
side effects include gynecomastia
and libido changes
flutamide
androgen receptor antagonist
fluorouracil
S phase antimetabolite
fluorouracil
causes
myelosuppression
fluorouracil
inhibits thymidylate synthase
24
fluorouracil
used to treat colon cancer and basal
cell carcinoma
etoposide
G2 phase inhibitor
etoposide
causes double stranded breaks in
DNA
etoposide
inhibits topoisomerase II
etoposide
used to treat small cell carcinoma of the lung and
prostate and testicular cancers
25
doxorubicin
intercalates in DNA to reduce
replication and transcription
doxorubicin
causes dilated cardiomyopathy
daunorubicin
used to treat AML
cyclophosphamide
causes hemorrhagic cystitis
cyclophosphamide
alkylating agent used to treat
cancers
26
cisplatin
alkylating agent
cisplatin
causes nephrotoxicity and acoustic
nerve damage
carmustine
alkylating agent that causes DNA cross-linking and
strand breaks
carmustine
used to treat brain tumors, highly lipophilic
nitrosourea drug
bleomycin
mixture of glycoproteins that produce free radicals
upon binding DNA
27
bleomycin
causes strand breaks in DNA
bleomycin
G2 phase inhibitor
bleomycin
can cause pulmonary fibrosis
anastrozole
inhibitor of steroid synthesis
anastrozole
inhibits conversion of
androstenedione to estrone
28
aminoglutethimide
blocks conversion of cholesterol to
pregnenolone
anastrazole
aromatase inhibitor
zidovudine
inhibits viral reverse transcriptase
zidovudine
chain terminator
zidovudine
given to prevent transmission of
HIV to neonates
29
vancomycin
used to treat MRSA
vancomycin
used to treat c. difficile
vancomycin
rapid IV infusion causes red man
syndrome
TMP-SMX
blocks folate synthesis
TMP-SMX
can cause megaloblastic anemia
30
TMP-SMX
do not give to pts with G6PDH
deficiency
trimethoprim blocks DHFR
sulfamethoxazole
blocks dihydropteroate synthase
tetracycline
inhibits 30s ribosome
tetracycline
bacteriostatic drug
31
tetracycline
CI in pregnant women due to bone dysplasia and
dental enamel defects
streptogramins p450 inhibitor
streptogramins
arthralgias and
myalgias
streptogramins
used to treat MRSA and VRE
rifampin
inhibits DNA-dependent RNA
polymerase
32
rifampin
imparts red-orange color to
secretions
ribavirin
guanosine analog
ribavirin
inibits steps in RNA synthesis
ribavirin
used to treat viral hemorrhagic
fevers and hepatitis C
ribavirin
used to treat RSV
33
quinine
blocks DNA replication and RNA transcription in p.
falciparum within RBCs
quinine
causes cinchonism
cinchonism
headache, vertigo, blurry vision,
tinnitus
mefloquine
used for prophylaxis of p. falciparum
due to low SE
quinine
used for malaria
34
pyrantel pamoate
stimulates nicotinic receptors in
nematodes
praziquantel
used for fluke and tapeworm
infections
polymyxin b
cationic detergent that disrupts
bacterial membranes
polymyxin b
causes neurotoxicity and acute
tubular necrosis
polymyxin b
only used topically
35
penicillins
inhibits transpeptidation step in bacterial cell wall
synthesis
oseltamivir
neuraminidase inhibitor that
prevent viral spreading
oseltamivir
used against influenza
a
nystatin
disrupts fungal membrane permeability by binding
to ergosterol
nystatin
used to treat oral candidiasis and
diaper rash
36
nitrofurantoin
can cause hemolysis in G6PDH
deficient patients
nitrofurantoin
can accumulate to toxic levels in patients with renal
failure
nitrofurantoin
urinary antiseptic that requires
acidification
nifurtimox
used to treat chagas disease
nevirapine
NNRTI used to treat
HIV
37
neomycin
used to treat hepatic encephalopathy
neomycin
prevents accumulation of
nitrogenous microbial metabolites
metronidazole
activated by anaerobes and parasites
metronidazole
interferes with nucleic acid synthesis
metronidazole
used to treat amebiasis, trichomoniasis, giariasis,
and c. diff
38
methicillin
bulky R-group prevents degradation
by penicillinase
nafcillin
bulky R-group prevents degradation
by penicillinase
dicloxacillin
bulky R-group prevents degradation
by penicillinase
methi, naf, diclox
beta lactams
mebendazole
inhibits microtubule synthesis and glucose uptake by
helminths
39
mebendazole
used to treat pinworms
albuterol
selective b2 agonist
atenolol
selective b1 blocker
acebutolol
selective b1 blocker
metoprolol
selective b1 blocker
40
detromethrophan
depresses cough center in the
medulla
metoclopramide
facilitates acetylcholine while blocking dopamine in
the enteric nervous system
metoclopramide
SE are sedation, diarrhea,
extrapyramidal symptoms
metoclopramide
prokinetic agent used to block
emesis
metoclopramide
blocks D2 receptors in the area
postrema
41
misoprostol PGE analog
misoprostol
decreases gastric acid production, increases mucus
production
misoprostol
eicosanoid preparation used for pts
taking lots of NSAIDs
omeprazole
H/K ATPase inhibitor
ondansetron
serotonin-3 inhibitor that acts at the
area postrema
42
sucralfate
requires acidic environment to
polymerize
sucralfate
cannot be used with antacids or H2
blockers
folic acid
will correct anemia but not neuro sx associated with
b12 deficiency
EPO
recombinant drug used for anemia
aminocaproic acid
orally active inhibitor of
plasminogen activation
43
aminocaproic acid inhibits fibrinolysis
aminocaproic acid
used for acute bleeding in
hemophilic patients
abciximab
antibody against glycoprotein 2b/3a
receptor
abciximab
prevents platelet activation
abciximab
anticoagulant preventing restenosis
after angioplasty
44
benztropine antimuscarinic
benztropine
CI are prostatic hyperplasia, GI
obstruction, glaucoma
benztropine
antimuscarinic used to treat tremors and rigidity in
parkinsons, but does nothing for bradykinesia
RhoGAM
antibody to Rh(D) antigen that
opsonizes
probenecid
competes with uric acid for reabsorption in the
proximal tubule
45
probenecid
inhibits secretion of weak acids
sulfinpyrazone
acts simliarly to probenecid
methylsergide
blocks serotonin receptors
methylsergide
causes fibroplasia of
retroperitoneum and
subendocardium
methylsergide
used to prevent migraines
46
daclizumab
binds IL-2 receptor on activated T
cells
daclizumab
used for patients with renal
allografts
bromocriptine D2 agonist
bromocriptine
inhibits PRL release
diphenhydramine
inhibit histamine binding to H1
receptors
47
diphenhydramine causes drowsiness
diphenhydramine
used for allergies and motion
sickness
cromolyn sodium
stabilizes mast cell membrane
lithium
inhibits IP3 and DAG
lithium
causes tremor, hypothyroidism,
polydipsia, polyuria
48
methylphenidate
stimulates the release of
catecholamines
phenytoin
inducer of p450
carbamazepine
inducer of p450
griseofulvin
inducer of p450
rifampin
inducer of p450
49
barbiturates
inducer of p450
penicillins bactericidal
cephalosporins bactericidal
vancomycin bactericidal
aminoglycosides
bactericidal
50
fluoroquinolones
bactericidal
metronidazole bactericidal
calcium channel
blockers
causes cutaneous flushing
adenosine
causes cutaneous flushing
vancomycin
causes cutaneous flushing
51
metronidazole
causes disulfiram-like reaction
cephalosporins
causes disulfiram-like reaction
procarbazine
causes disulfiram-like reaction
nitrous oxide has a high MAC
phenelzine MAOI
52
tranylcypromine
MAOI
isocarboxazid MAOI
MAOI + SSRI
serotonin syndrome
MAOI
inhibits breakdown of amine
neurotransmitters
mebendazole
microtubule inhibitor
53
thiabendazole
microtubule inhibitor
paclitaxel
microtubule inhibitor
vincristine
microtubule inhibitor
colchicine
microtubule inhibitor
griseofulvin
microtubule inhibitor
54
hydralazine
SLE like syndrome
procainamide
SLE like syndrome
isoniazid
SLE like syndrome
phenytoin
SLE like syndrome
halothane
massive hepatic
necrosis
55
acetaminophen
massive hepatic
necrosis
valproic acid
massive hepatic
necrosis
cimetidine p450 inhibitor
ketoconazole p450 inhibitor
erythromycin p450 inhibitor
56
cimetidine gynecomastia
ketoconazole gynecomastia
spironolactone gynecomastia
bleomycin
pulmonary fibrosis
amiodarone
pulmonary fibrosis
57
busulfan
pulmonary fibrosis
aminoglycosides
ototoxic and
nephrotoxic
loop diuretics
ototoxic and
nephrotoxic
cisplatin
ototoxic and
nephrotoxic
vancomycin
mildly ototoxic and nephrotoxic
58
penicillamine
used to treat wilson disease
penicillamine
used to treat RA
penicillamine
used to treat copper toxicity bc it is a
chelator
organophosphates
anticholinesterases used in chemical
warfare
pralidoxime
antidote for anticholinesterases such
as organophosphates
59
naloxone
mu opioid receptor antagonist
naloxone
used to treat opioid overdose
phenobarbital
binds GABA receptors
phenobarbital
increases the duration of chloride
channel opening
phenobarbital
used to treat tonic-clonic seizures
and crigler-najjar
60
phenytoin
interferes with folate absorption
phenytoin
SE are gingival hyperplasia, hirsutism, anemia, and
birth defects
phenytoin
class 1b antiarrhythmic
risperidone
blocks D2 and serotonin-2 receptors
risperidone
causes high sedation
61
risperidone
atypical antipsychotic with lots of
extrapyramidal SE
ropinirole
forestalls the use of levodopa in
parkinson's disease
methanol
causes damage by being converted to formaldehyde
in the liver
methanol
retinal damage, blindness, metabolic
acidosis, coma
flumazenil
antagonizes benzodiazepines and
zolpidem
62
flumazenil
used for benzodiazepine overdose
ethylene glycol
causes metabolic acidosis and precipitation of
oxalate crystals in the kidney
dimercaprol
chelates metals to keep them from
damaging proteins
succimer
orally active metal chelator
dimercaprol
used to treat heavy metal poisoning
63
digibind
fab fragment antibody
deferoxamine
rapid infusion causes hypotensive
shock
deferoxamine
used to treat acute iron toxicity
dantrolene
decreases the release of calcium from the
sarcoplasmic reticulum
dantrolene
used to treat malignant
hyperthermia
64
selegiline inhibits MAO-B
MAO-B
degrades dopamine
selegiline
inhibits degradation of dopamine in CNS, used with
levodopa for parkinson's
thiopental
ultra-short acting barbiturate used to induce surgical
anesthesia
alprazolam
intermediate-acting benzodiazepine used for panic
disorder and phobias
65
n-acetylcysteine
protects against fulminant hepatic
failure
n-acetylcysteine
used for acetaminophen overdose
carvedilol used for CHF
carvedilol
nonselective beta blocker and
alpha-1 blocker
amiodarone
blocks sodium
channels
66
amiodarone
corneal microdeposits
amiodarone
class III antiarrythmic
adenosine
short acting agent given IV for AV
nodal arrhythmias
spironolactone
potassium sparing diuretic
spironolactone
aldosterone antagonist
67
spironolactone
functions at the collecting tubule
nitroprusside
stimulates guanyl cyclase
nitroprusside
increases cGMP in vascular smooth
muscle
minoxidil
direct-acting vasodilator
minoxidil
used topically bc of benefit of
hypertrichosis
68
cholestyramine
bind bile acids to prevent
enterohepatic recycling
fexofenadine
nonsedating antihistaminic
loratadine
nonsedating antihistaminic
ipratropium
dry mouth side effect
ipratropium
antimuscarinic for COPD and
asthma
69
salmeterol
may cause tremors and arrhythmias
theophylline
methylxanthine used for asthma
theophylline
inhibits phosphodiesterase
theophylline
inhibits conversion of cAMP to AMP
octreotide
used to treat carcinoid, gastrinoma, somatotropic
pituitary adenoma
70
propylthiouracil
inhibits iodination step of thyroid
hormone synthesis
methimazole
same as PTU but crosses placenta
and enters breast milk
raloxifene
estrogen partial
agonist
raloxifene
does not increase the risk of
endometrial cancer
tamoxifen
increases risk of endometrial cancer
71
repaglinide
rapid onset
sulfonylurea
repaglinide
binds potassium channels to
facilitate insulin release
glitazones
increase insulin sensitivity
glitazones
stimulate PPAR-gamma receptor
troglitazone hepatotoxic
72
sulfonylureas
stimulate closure of potassium
channels
sulfonylureas
glyburide and glipizide
sulfonylureas
cause release of preformed insulin
acyclovir
used to treat herpes
acyclovir
guanosine analog
73
acyclovir
activated by thymidine kinase of the
virus it treats
acyclovir
functions as a chain terminator when incorporated
into viral DNA
amantadine
prophylaxis against influenza A and
rubella
amantidine
inhibits fusion of viral particles within endosome of
the cell
amantidine
not effective against influenza B
74
amantidine
binds to M2 protein
amphotericin B
disrupts fungal membranes by
binding ergosterol
mifepristone
blocks binding of progesterone to
cytoplasmic receptors
ampicillin
extended spectrum penicillin used to
treat gram negatives
aztreonam
b-lactamase resistant monobactam
75
aztreonam
used only with aminoglycosides
against gram negative rods
aztreonam
cannot be used against gram
positives or anaerobic bacteria
bacitraicin
inhibits bacterial cell wall synthesis
piperacillin
used against enterobacter and
pseudomonas
carbenicillin
used against enterobacter and
pseudomonas
76
ticarcillin
used against enterobacter and
pseudomonas
ceftriaxone
used for septic meningitis
cefixime
used to treat
gonnorhea
chloramphenicol
gray baby syndrome in babies deficient in hepatic
gluconosyltransferase
chloramphenicol aplastic anemia
77
fludrocortisone
used in postadrenalectomy therapy
chloroquine
primary drug for acute malaria
chloroquine
disrupts hemoglobin breakdown, with toxic
accumulation of heme in RBC
clavulanic acid
beta lactamase
inhibitor
sulbactam
beta lactamase
inhibitor
78
tazobactam
beta lactamase
inhibitor
clindamycin
bacteriostatic at the 50s ribosome
clindamycin
treatment of
bacteroides
didanosine (ddI)
dose-limiting pancreatitis
lamivudine
inhibits reverse transcriptase of
hepatitis B
79
erythromycin
bacteriostatic inhibitor of 50s
erythromycin macrolide
azithromycin macrolide
clarithromycin macrolide
erythromycin
GI irritation and acute cholestatic
hepatitis
80
metformin
biguanide compound
metformin
increases peripheral glycolysis
clomiphene
blocks negative feedback at the
pituitary
cosyntropin
used for diagnosis of addison's
disease
danazol
inhibitor of p450
81
danazol
used for endometriosis and fibrocystic disease of the
breast
desmopressin
selective V2 agonist
vasopression
V1 and V2 agonist
vasopressin
used to treat esophageal varices
DES
clear cell carcinoma of the vagina in
daughters
82
ethinyl estradiol/mestranol
lowers risk of coronary disease, slows osteoporosis,
ameliorates hot flashes
HRT
increased risk of breast and ovarian
cancer
zileutin
inhibits leukotriene synthesis
monteleukast
LTD4 and LTE4
antagonist
acarbose
inhibits a-galactosidase
83
bisphosphonates esophageal ulcerations
bromocriptine
used to treat hyperprolactinemia
due to pituitary adenoma
bromocriptine ergot alkaloid
diphenoxylate
suppress GI motility
loperamide
suppress GI motility
84
cisapride
stimulates peristalsis by release of Ach from
myenteric plexus
cisapride long QT
magnesium hydroxide laxative antacid
aluminum hydroxide constipating antacid
ipecac syrup
acts to stimulate chemoreceptor
trigger zone of the medulla
85
cimetidine
gynecomastia and galactorrhea
cimetidine p450 inhibitor
calcium carbonate hypercalcemic alkalosis
calcium carbonate
renal calculi
bismuth subsalicylate
used with metronidazole and tetracycline for PUD
caused by h.pylori
86
warfarin
interferes with vitamin K dependent
clotting factors
alteplase
converts fibrin-bound plasminogen
to plasmin
ticlopidine
platelet antiaggregant
ticlopidine
interferes with binding of fibrin to Gp2b/3a receptor
on platelets
streptokinase
catalyzes conversion of plasminogen
to plasmin
87
fluconazole
inhibits formation of ergosterol
fluconazole
prophylaxis against cryptococcus
neoformans
fluconazole
used to treat oral candidiasis
fluoroquinolones
bactericidal inhibitor of DNA gyrase
fluoroquinolones
used for gram negative rods, some gram positives,
and neisseria
88
fluoroquinolones bad for cartilage
sargramostim
recombinant GM-CSF
filgrastim G-CSF
hydroxyurea
used for sickle cell crisis
hydroxyurea
increases levels of HbF
89
hydroxyurea
inhbits DNA synthesis by blocking conversion of
ribonucleotides to deoxyribonucleotides
foscarnet treats CMV
foscarnet
inhibits viral DNA polymerase
ganciclovir
metabolized by viral transferases
ganciclovir
requires phosphorylation by viral
kinases to work
90
ganciclovir
guanosine analog converted by CMV
to triphosphorylated form
ganciclovir
SE: neutropenia, leukopenia,
thrombocytopenia
griseofulvin
keratinized tissue
griseofulvin ringworm
griseofulvin binds tubulin
91
carbapenem
given with cliastatin
carbapenem
used against gram positive cocci, gram negative rods,
and anaerobes
ritonavir
inhibit protease in the HIV pol gene
isoniazid
inhibits synthesis of mycolic acid
isoniazid
SE neuritis and hepatitis
92
ethambutol TB
pyrazinamide TB
rifampin TB
streptomycin TB
sulfonamides
stevens-johnson
93
ethosuxamide
stevens-johnson
lamotrigine
stevens-johnson
penicillins
erythema multiforme
barbiturates
erythema multiforme
salicylates
erythema multiforme
94
hydantoins
erythema multiforme
antimalarials
erythema multiforme
sulfonamides G6PDH
isoniazid G6PDH
primaquine G6PDH
95
tetracycline
photosensitivity
amiodarone
photosensitivity
sulfonamides
photosensitivity
bethanechol
muscarinic agonist
carbachol
nicotinic and muscarinic agonist
96
ephedrine ma-huang
phenoxybenzamine
adrenergic antagonist (alpha
receptors)
phentolamine
used in diagnosing
pheochromocytoma
ivermectin
onchocera volvulus and
strongyloides stercoralis
ivermectin
increases GABA transmission in the
worm
97
ketoconazole
interfere with fungal cell wall
synthesis
pilocarpine
treatment of glaucoma
pilocarpine
muscarinic agonist
prazosin
first dose syncope
prazosin miosis
98
pyridostigmine
used for tubocurarine toxicity
scopolamine
competitive cholinergic antagonist
used for motion sickness
succinylcholine muscle relaxant
succinylcholine
nicotinic agonist that opens sodium
channels
tubocurarine
nondepolarizing neuromuscular
ganglionic blockers
99
acetazolamide
inhibits carbonic anhydrase in the proximal
convoluted tubule
acetazolamide
metabolic acidosis
acetazolamide
give to alkalinize the urine in aspirin
toxicity
amiloride
block sodium channels in the
cortical collecting tubules
amiloride
hyperkalemic metabolic acidosis
100
captopril
inhibit breakdown of bradykinin
ketamine
should be given with
benzodiazepines
gabapentin
partial seizures
ethosuxamide
inhbits T-type calcium channels
entacapone
inhibits conversion of levodopa to
3-0-methyldopa
101
HCTZ
hypokalemia, alkalosis,
hyperuricemia, hyperlipidemia
captopril
functions at the collecting tubules
losartan
functions at the collecting tubules
losartan
CI in pregnancy
captopril
CI in pregnancy