PT 539 Pharmacology 9/4/2014 Priming activity Perdomo

The primary objective of this priming activity is to: 1) encourage utilization of the pharmacology book
and 2) provide a foundation for understanding key concepts in Pharmacology.
Briefly define & explain the following concepts. Refer to Chapter 1 -4 for answers.
Please type your answers using a font of 12, single space each answer but double space between
questions.

a. Define Pharmacokinetics (1pt)


b. Define Pharmacodynamics (1pt)


c. What is the significance of a drug being referred to either by its trade name or generic name?
(1pt)


d. Define bioavailability and give an example of which route of administration will allow for greater
bioavailability. (2pt)


e. Describe 2 disadvantages for drugs being given orally. (2 pts)


f. If drug A elicits a response equal to drug B but at a lower dosage, drug A is described as being
more ___________ than drug B. (1 pt)


g. What is the significance of a drugs Therapeutic Index (Ti)? (1 pt)


h. What is the therapeutic significance of the concept of First Pass? (2 pts)


i. What organs are primarily responsible for pharmacokinetic activity of a drug? (2 pts)


j. What is the implication of a drug being described as an agonist? (2 pts)