<script type="text/javascript">

var uploader = document.getElementById('uploader');

upclick(
{
element: uploader,
action: '/path_to/you_server_script.php',
onstart:
function(filename)
{
alert('Start upload: '+filename);
},
oncomplete:
function(response_data)
{
alert(response_data);
}
});
</script>
Write server-side script.
Uploaded data have name Filedata.
Server-side script example 1
<?php
$tmp_file_name = $_FILES['Filedata']['tmp_name'];
move_uploaded_file($tmp_file_name, '/path_to/new_filename');
Server-side script example 2
<?php
$tmp_file_name = $_FILES['Filedata']['tmp_name'];
$ok = move_uploaded_file($tmp_file_name, '/path_to/new_filename');
// This message will be passed to 'oncomplete' function
echo $ok ? "OK" : "FAIL";
SOURCE: GOOGLE CODE