Of 1 PRESENTORS: ALBERCA, Michelle J. BAROTAC, Razil L. COMPRA, Anne rose J. EUSALA, eene E. L!O"#, ris Madeline E. LLAMERA, Joac$i%% A. M!"AR&O, Shen' #. PAC(A"O. Ana Mae O. PARE&ES, Riza Mae M. S!"CO, Mar$ e)in #. Table of Contents !. &edication i 2 !!. Ac$no*ledge%ent ii !!!. !ntroduction + !,. Re)ie* o- Related Literature . ,. Anato%' and Ph'siolog' +/ ,!. Patient0s (ealth (istor' .1 A. Biogra2hic &ata .3 B. (istor' o- Present !llness .4 C. Past (ealth (istor' .5 a. Childhood !llness .5 6. !%%unization .5 c. (istor' o- (os2italization .5 d. Surgical (istor' .5 e. Accidents and !n7uries .5 -. Allergic and T'2e o- Reaction .5 g. 8a%il' (ealth (istor' .5 h. Personal (ealth (istor' .9 +. Li-est'le .9 +.+ Personal ha6its .9 +.. &iet .9 +./ Slee2 and rest:2attern .; +.1 Eli%ination Pattern .; +.3 Acti)ities o- &ail' Li)ing <A&L= .; +.4 Recreation and (o66ies /> i. Social &ata /> +. Occu2ational &ata /> 7. En)iron%ental &ata /> $. Ps'chological &ata /> l. Patterns o- (ealth Care /> ,!!. Re)ie* o- S'ste% /+ a. !ntegu%entar' S'ste% /+ 6. (ead, E'es, Ears, "ose, Throat< (EE"T= /+ c. "ec$ /+ d. Breast and A?illae /+ e. Thora? and Lungs /+ -. Cardio)ascular S'ste% /+ g. #astrointestinal S'ste% /+ h. Musculos$eletal S'ste% /+ i. "eurologic S'ste% /. 7. Urinar' S'ste% /. $. Re2roducti)e S'ste% /. l. (e%atologic /. %. Endocrine /. 3 n. Ps'chiatric /.
,!!!. Ph'sical Assess%ents // a. #eneral Sur)e' // 6. ,ital signs // c. !ntegu%entar' S'ste% // d. (air // e. "ails // -. (ead /1 g. E'es and )ision /1 h. Ears and hearing /1 i. "ose and sinusitis /1 7. Oro2har'n? <%outh and throat= /1 $. "ec$ /3 l. Thora? and lungs /3 %. Breast and A?illae /3 n. A6do%en /3 o. Musculos$eletal s'ste% /3 2. Cardio)ascular s'ste% /4 @. Urinar' s'ste% /4 r. #astrointestinal s'ste% /4 s. "eurologic s'ste% /4 a. Cranial ner)es !: A!! /5 6. #lass Co%a Scale /; c. Muscle Strength 1+ !A. &octor0s Order <detailed= 1. A. La6orator' &ata 11 t. Urinal'sis 11 u. (e%atolog' 11 A!. &rug Stud' 13 A!!. Patholog' and Ph'siolog' o- #BS 3> A!!!. "ursing Care Plan <"CP= 3. A!,. &ischarge Plan <detailed= 44 A,. A22endi? 49 a. !, Record 49 6. #enogra% 4; A,!. &e-inition o- Ter%s 5> A,!!. Re-erences 54 Introdution 4 Be ha)e ner)es that li)e outside the central ner)ous s'ste% <the 6rain and s2inal cord=, and deal *ith our 6od'Cs senses and %o)e%ents. These are called our 2eri2heral ner)es. #uillain:Barre s'ndro%e <also $no*n as acute in-la%%ator' or 2ost:in-ecti)e 2ol'radiculoneuro2ath'= is a rare 6ut serious disease o- the 2eri2heral ner)ous s'ste%. !t %a$es the 6od's o*n i%%une s'ste% attac$ the ner)es, causing *ides2read in-la%%ation that leads to a tingl', nu%6ing sensation in the ar%s and legs. This can e)entuall' result in a short:ter% loss o- -eeling and %o)e%ent <te%2orar' 2aral'sis=.!t is slightl' %ore co%%on in %en than *o%en, and can a--ect 2eo2le o- an' age, e)en children. Bhat e?actl' causes the condition is unclear and there is no *a' to 2in2oint *ho %a' 6e %ost at ris$. (o*e)er, in %ost cases o- #uillain:Barre s'ndro%e the 2erson had a )irus or 6acterial in-ection in the last -our *ee$s. Most 2eo2le *ill %a$e a -ull reco)er' *ithin a -e* *ee$s or %onths, *ith no -urther trou6le. So%e cases ta$e longer to reco)er -ro% and there is a 2ossi6ilit' o- 2er%anent ner)e da%age. Patient R is a +4 'ears old %ale, single *ho resides at Es2eranza, Loreto, &inagat !sland is an e%6odi%ent o- rare 2eo2le *ho ha)e #BS. (e *as ad%itted at Caraga Regional (os2ital last Se2te%6er .3, .>>; *ith the chie- co%2laint o- sudden onset o- *ea$ness o- le-t lo*er e?tre%ities then a-ter the right e?tre%ities -or al%ost / *ee$s under the care o- &r. Asodisen. Be chose 2atient R0s case -or our case stud' 6ecause *e thin$ it is interesting though it0s rarel' seen .!t is a cul2rit condition that can cause te%2orar' 2aral'sis and can a--ect our acti)ities o- dail' li)ing since in #BS *e can -eel *ea$ness and nu%6ness in our 6od' that0s *h' 2atient couldn0t *al$ and ha)e li%ited range o- %otion. !t0s not so de2ressing though there is a glint ho2e *ith the 2ro2er %edical attention, the s'ndro%e %a' 6e re)ersed. Be are ho2ing that through this case stud' *e can i%2art $no*ledge and 6etter understanding o- #BS to the co%%unit' -or the% to 6e a*are o- the said s'ndro%e. Re!ie" of Related #iterature 5 $%at is &uillain 'arre( Syndrome) #uillain:Barre s'ndro%e is a serious disorder that occurs *hen the 6od'Cs de-ense <i%%une= s'ste% %ista$enl' attac$s 2art o- the ner)ous s'ste%. This leads to ner)e in-la%%ation that causes %uscle *ea$ness. #uillain:BarrD s'ndro%e is an acute, usuall' ra2idl' 2rogressi)e in-la%%ator' 2ol'neuro2ath' characterized 6' %uscular *ea$ness and %ild distal sensor' loss. Cause is thought to 6e autoi%%une. #uillain:BarrD s'ndro%e is the %ost co%%on ac@uired in-la%%ator' neuro2ath'. Although the cause is not -ull' understood, it is thought to 6e autoi%%une. There are se)eral )ariants. !n so%e, de%'elination 2redo%inatesE others a--ect the a?on. !n a6out . F / o- 2atients, the s'ndro%e 6egins 3 da's to / *$ a-ter a 6acterial in-ectious disorder, surger', or )accination. !n-ection is the trigger in G 3>H o- 2atientsE co%%on 2athogens include Ca%2'lo6acter 7e7uni, enteric )iruses, her2es )iruses <including c'to%egalo)irus and E2stein:Barr )irus=, and M'co2las%a s2. A cluster o- cases -ollo*ed the s*ine -lu )accination 2rogra% in +;53. $%at are t%e auses) #uillain:Barre s'ndro%e is an autoi%%une disorder <the 6od'Cs i%%une s'ste% attac$s itsel-=. E?actl' *hat triggers #uillain:Barre s'ndro%e is un$no*n. The s'ndro%e %a' occur at an' age, 6ut is %ost co%%on in 2eo2le o- 6oth se?es 6et*een ages /> and 3>. !t o-ten -ollo*s a %inor in-ection, usuall' a lung in-ection or gastrointestinal in-ection. Usuall', signs o- the original in-ection ha)e disa22eared 6e-ore the s'%2to%s o- #uillain:Barre 6egin. #uillain:Barre s'ndro%e causes in-la%%ation that da%ages 2arts o- ner)es. This ner)e da%age causes tingling, %uscle *ea$ness, and 2aral'sis. The in-la%%ation usuall' a--ects the ner)eCs co)ering <%'elin sheath=. Such da%age is called de%'elination. &e%'elination slo*s ner)e signaling. &a%age to other 2arts o- the ner)e can cause the ner)e to sto2 *or$ing. #uillain:Barre s'ndro%e %a' occur along *ith )iral in-ections such asI A!&S 6 (er2es si%2le? Mononucleosis !t %a' also occur *ith other %edical conditions such as s'ste%ic lu2us er'the%atosus or (odg$inCs disease.So%e 2eo2le %a' get #uillain:Barre s'ndro%e a-ter a 6acterial in-ection or certain )accinations <such as ra6ies and s*ine -lu=. A si%ilar s'ndro%e %a' occur a-ter surger', or *hen criticall' ill. $%at are t%e ris* fators) #uillain:Barre s'ndro%e can a--ect all age grou2s, 6ut 'ouCre at greater ris$ i-I JouCre a 'oung adult JouCre an older adult #uillain:Barre %a' 6e triggered 6'I Most co%%onl', in-ection *ith ca%2'lo6acter, a t'2e o- 6acteria o-ten -ound in undercoo$ed -ood, es2eciall' 2oultr'. Surger' E2stein:Barr )irus (odg$inCs disease Mononucleosis (!,, the )irus that causes A!&S Rarel', ra6ies or in-luenza i%%unizations $%at are t%e sym+toms) S'%2to%s o- #uillain:Barre can get *orse )er' @uic$l'. !t %a' ta$e onl' a -e* hours to reach the %ost se)ere s'%2to%s, 6ut *ea$ness increasing o)er se)eral da's is also co%%on. Muscle *ea$ness or the loss o- %uscle -unction <2aral'sis= a--ects 6oth sides o- the 6od'. !n %ost cases, the %uscle *ea$ness starts in the legs and then s2reads to the ar%s. This is called ascending 2aral'sis. Patients %a' notice tingling, -oot or hand 2ain, and clu%siness. !- the in-la%%ation a--ects the ner)es to the dia2hrag%, and there is *ea$ness in those %uscles, the 2erson %a' need 6reathing assistance. T'2ical s'%2to%s includeI Loss o- re-le?es in the ar%s and legs 7 Muscle *ea$ness or loss o- %uscle -unction <2aral'sis= o !n %ild cases, there %a' 6e no *ea$ness or 2aral'sis o Ma' 6egin in the ar%s and legs at the sa%e ti%e o Ma' get *orse o)er .1 to 5. hours o Ma' occur in the ner)es o- the head onl' o Ma' start in the ar%s and %o)e do*n*ard o Ma' start in the -eet and legs and %o)e u2 to the ar%s and head "u%6ness, decreased sensation Sensation changes Tenderness or %uscle 2ain <%a' 6e a cra%2:li$e 2ain= Uncoordinated %o)e%ent Additional s'%2to%s %a' includeI Blurred )ision Clu%siness and -alling &i--icult' %o)ing -ace %uscles Muscle contractions Pal2itations <sensation o- -eeling heart6eat= E%ergenc' s'%2to%s <see$ i%%ediate %edical hel2=I Breathing te%2oraril' sto2s CanCt ta$e a dee2 6reath &i--icult' 6reathing &i--icult' s*allo*ing &rooling 8ainting 8eeling light:headed *hen standing 8laccid *ea$ness 2redo%inates in %ost 2atientsE it is al*a's %ore 2ro%inent than sensor' a6nor%alities and %a' 6e %ost 2ro%inent 2ro?i%all'. Relati)el' s'%%etric *ea$ness *ith 2aresthesias usuall' 6egins in the legs and 2rogresses to the ar%s, 6ut it occasionall' 6egins in the ar%s or head. !n ;>H o- 2atients, *ea$ness is %a?i%al at / *$. &ee2 tendon re-le?es are lost. S2hincters are usuall' s2ared. 8acial and oro2har'ngeal %uscles are *ea$ in G 3>H o- 2atients *ith se)ere disease. &eh'dration and undernutrition %a' result. Res2irator' 2aral'sis se)ere enough to re@uire endotracheal intu6ation and %echanical )entilation occurs in 3 to +>H. A -e* 2atients <2ossi6l' *ith a )ariant -or%= ha)e signi-icant, li-e:threatening autono%ic d's-unction causing BP -luctuations, ina22ro2riate A&( secretion, cardiac arrh'th%ias, #! stasis, urinar' retention, and 2u2illar' changes. An unusual )ariant <8isher )ariant= %a' cause onl' o2hthal%o2aresis, ata?ia, and are-le?ia. 8 ,o" to o+e "it% &uillain 'arre Syndrome) The e%otional i%2act o- #uillain:Barre s'ndro%e can 6e de)astating. !n se)ere cases, #uillain:Barre s'ndro%e can trans-or% 'ou -ro% health' and inde2endent to criticall' ill and 2h'sicall' hel2less K suddenl', and *ithout *arning. Although %ost 2eo2le e)entuall' reco)er -ull', a diagnosis o- #uillain:Barre s'ndro%e %eans con-ronting the 2ossi6ilit' o- long:ter% disa6ilit' or 2aral'sis. And those *ho do de)elo2 these co%2lications %ust ad7ust to lasting, li%ited %o6ilit' and a de2endence on others to hel2 %anage dail' acti)ities. Tal$ing *ith a %ental health 2ro)ider can 2la' a criticall' i%2ortant role in hel2ing 'ou co2e *ith the %ental and e%otional strain o- this illness. !n so%e cases, 'our thera2ist %a' reco%%end -a%il' counseling to hel2 'ou and 'our lo)ed ones ad7ust to the changes caused 6' #uillain:Barre s'ndro%e. Jou %a' also 6ene-it -ro% tal$ing *ith others *ho ha)e e?2erienced this illness. As$ 'our doctor or %ental health 2ro)ider to reco%%end a su22ort grou2 -or 2eo2le and -a%ilies co2ing *ith #uillain:Barre s'ndro%e. $%en to Contat a -edial Professional) See$ i%%ediate %edical hel2 i- 'ou ha)e an' o- the -ollo*ing s'%2to%sI CanCt ta$e a dee2 6reath &ecreased -eeling <sensation= o &i--icult' 6reathing o &i--icult' s*allo*ing o 8ainting o Loss o- %o)e%ent Tingling that started in 'our -eet or toes and is no* ascending u2*ard through 'our 6od' Tingling or *ea$ness thatCs s2reading ra2idl' Tingling that in)ol)es 6oth 'our hands and -eet &i--icult' catching 'our 6reath Cho$ing on sali)a #uillain:Barre s'ndro%e is a serious disease that re@uires i%%ediate hos2italization 6ecause o- the ra2id rate at *hich it *orsens. The sooner a22ro2riate treat%ent is started, the 6etter the chance o- a good outco%e. .lternati!e Names Landr':#uillain:Barre s'ndro%eE #BSE Acute idio2athic 2ol'neuritisE !n-ectious 2ol'neuritisE Acute in-la%%ator' 2ol'neuro2ath' 9 $%at is t%e +re!ention) Because so little is $no*n a6out *hat causes #BS to de)elo2, there are no $no*n %ethods o- 2re)ention. $%at is a /syndrome/) A s'ndro%e is a %edical condition, characterized 6' a collection o- s'%2to%s <that the 2atient -eels= and signs <that a doctor can o6ser)e or %easure=, rather than 6' a s2eci-ic organis% that causes the disease. "o one $no*s *hat causes #BS. S'%2to%s and signs can )ar' a great deal in #BS 2atients, so%eti%es %a$ing it di--icult to diagnose, es2eciall' in the earl' stages. 0iagnosis #uillain:Barre s'ndro%e can 6e di--icult to diagnose in its earliest stages. !ts signs and s'%2to%s are si%ilar to those o- other neurological disorders and %a' )ar' -ro% 2erson to 2erson. The -irst ste2 in diagnosing #uillain:Barre s'ndro%e is -or 'our doctor to ta$e a care-ul %edical histor' to -ull' understand the cluster o- signs and s'%2to%s 'ouCre e?2eriencing. A s2inal ta2 <lu%6ar 2uncture= and ner)e -unction tests are co%%onl' used to hel2 con-ir% a diagnosis o- #uillain:Barre s'ndro%e. S+inal ta+ 1lumbar +unture2 This 2rocedure in)ol)es *ithdra*ing a s%all a%ount o- -luid -ro% 'our s2inal canal at 'our lo* 6ac$ <lu%6ar= le)el. This cere6ros2inal -luid is then tested -or a s2eci-ic t'2e o- change that co%%onl' occurs in 2eo2le *ho ha)e #uillain:Barre s'ndro%e. Ner!e funtion tests Jour doctor %a' *ant in-or%ation -ro% t*o t'2es o- ner)e -unction tests K electro%'ogra2h' and ner)e conduction )elocit'I Eletromyogra+%y reads electrical acti)it' in 'our %uscle to deter%ine i- 'our *ea$ness is caused 6' %uscle da%age or ner)e da%age. Ner!e ondution studies assess ho* 'our ner)es and %uscles res2ond to s%all electrical sti%uli. &iagnosis is 2ri%aril' clinical. Si%ilar acute *ea$ness can result -ro% %'asthenia gra)is, 6otulis%, 2olio%'elitis <%ainl' outside the US=, tic$ 2aral'sis, Best 10 "ile )irus in-ection, and %eta6olic neuro2athies, 6ut these disorders can usuall' 6e distinguished as -ollo*sI M'asthenia gra)is is inter%ittent and *orsened 6' e?ertion. Botulis% %a' cause -i?ed dilated 2u2ils <in 3>H= and 2ro%inent cranial ner)e d's-unction *ith nor%al sensation. Polio%'elitis usuall' occurs in e2ide%ics. Tic$ 2aral'sis causes ascending 2aral'sis 6ut s2ares sensation. Best "ile )irus causes headache, -e)er, and as'%%etric -laccid 2aral'sis 6ut s2ares sensation. Meta6olic neuro2athies occur *ith a chronic %eta6olic disorder. Tests -or in-ectious disorders and i%%une d's-unction, including tests -or he2atitis and (!, and seru% 2rotein electro2horesis, are done. !- #uillain:BarrD s'ndro%e is sus2ected, 2atients should 6e ad%itted to a hos2ital -or electrodiagnostic testing, CS8 anal'sis, and %onitoring 6' %easuring -orced )ital ca2acit' e)er' 4 to 9 h. !nitial electrodiagnostic testing detects slo* ner)e conduction )elocities and e)idence o- seg%ental de%'elination in .L/ o- 2atientsE ho*e)er, nor%al results do not e?clude the diagnosis and should not dela' treat%ent. CS8 anal'sis %a' detect al6u%inoc'tologic dissociation <increased 2rotein 6ut nor%al BBC count=, 6ut it %a' not a22ear -or u2 to + *$ and does not de)elo2 in +>H o- 2atients. Prognosis Although so%e 2eo2le can ta$e %onths and e)en 'ears to reco)er, %ost cases o- #uillain:Barre s'ndro%e -ollo* this general ti%elineI 8ollo*ing the -irst s'%2to%s, the condition tends to 2rogressi)el' *orsen -or a6out t*o *ee$s. S'%2to%s reach a 2lateau and re%ain stead' -or t*o to -our *ee$s. Reco)er' 6egins, usuall' lasting si? to +. %onths. This s'ndro%e is -atal in M .H. Most 2atients i%2ro)e considera6l' o)er a 2eriod o- %onths, 6ut a6out />H o- adults and e)en %ore children ha)e so%e residual *ea$ness at / 'r. Patients *ith residual de-ects %a' re@uire retraining, ortho2edic a22liances, or surger'. 11 A-ter initial i%2ro)e%ent, / to +>H o- 2atients de)elo2 chronic in-la%%ator' de%'elinating 2ol'neuro2ath' <C!&PKsee 6elo*=. Reco)er' can ta$e *ee$s or 'ears. Most 2eo2le sur)i)e and reco)er co%2letel'. According to the "ational !nstitute o- "eurological &isorders and Stro$e, a6out />H o- 2atients still ha)e so%e *ea$ness a-ter / 'ears. Mild *ea$ness %a' 2ersist -or so%e 2eo2le. A 2atientCs outco%e is %ost li$el' to 6e )er' good *hen the s'%2to%s go a*a' *ithin / *ee$s a-ter the' -irst started. Co%2lications o- #uillan:Barre s'ndro%e can includeI 'reat%ing diffiulties. A 2otentiall' deadl' co%2lication o- #uillain:Barre s'ndro%e is that the *ea$ness or 2aral'sis can s2read to the %uscles that control 'our 6reathing. Jou %a' need te%2orar' hel2 -ro% a %achine to 6reathe *hen 'ouCre hos2italized -or treat%ent. Residual numbness or ot%er sensations. Most 2eo2le *ith #uillain:Barre s'ndro%e reco)er co%2letel' or ha)e onl' %inor, residual *ea$ness or a6nor%al sensations, such as nu%6ness or tingling. (o*e)er, -ull reco)er' %a' 6e slo*, o-ten ta$ing a 'ear or longer. Breathing di--icult' <res2irator' -ailure= Contractures o- 7oints or other de-or%it' &ee2 )ein thro%6osis <6lood clots that -or% *hen so%eone is inacti)e or con-ined to 6ed= !ncreased ris$ o- in-ections Lo* or unsta6le 6lood 2ressure Per%anent loss o- %o)e%ent o- an area Pneu%onia Suc$ing -ood or -luids into the lungs <as2iration= 12 Treatment ThereCs no cure -or #uillain:Barre s'ndro%e. But t*o t'2es o- treat%ents s2eed reco)er' and reduce the se)erit' o- #uillain:Barre s'ndro%eI Bhen s'%2to%s are se)ere, the 2atient *ill need to go to the hos2ital -or 6reathing hel2, treat%ent, and 2h'sical thera2'. Plasma+%eresis. A %ethod called 2las%a2heresis is used to re%o)e 2roteins, called anti6odies, -ro% the 6lood. The 2rocess in)ol)es ta$ing 6lood -ro% the 6od', usuall' -ro% the ar%, 2u%2ing it into a %achine that re%o)es the anti6odies, then sending it 6ac$ into the 6od'. This treat%ent K also $no*n as 2las%a e?change K is a t'2e o- N6lood cleansingN in *hich da%aging anti6odies are re%o)ed -ro% 'our 6lood. Plas%a2heresis consists o- re%o)ing the li@uid 2ortion o- 'our 6lood <2las%a= and se2arating it -ro% the actual 6lood cells. The 6lood cells are then 2ut 6ac$ into 'our 6od', *hich %anu-actures %ore 2las%a to %a$e u2 -or *hat *as re%o)ed. !tCs not clear *h' this treat%ent *or$s, 6ut scientists 6elie)e that 2las%a2heresis rids 2las%a o- certain anti6odies that contri6ute to the i%%une s'ste% attac$ on the 2eri2heral ner)es. Plas%a2heresis <see Trans-usion MedicineI Plas%a2heresis= hel2s *hen done earl' in the s'ndro%eE it is used i- O:glo6ulin is ine--ecti)e. Plas%a2heresis is relati)el' sa-e, shortens the disease course and hos2ital sta', and reduces %ortalit' ris$ and incidence o- 2er%anent 2aral'sis. Plas%a2heresis re%o)es an' 2re)iousl' ad%inistered O:glo6ulin, negating its 6ene-its. Intra!enous immunoglobulin. !%%unoglo6ulin contains health' anti6odies -ro% 6lood donors. (igh doses o- i%%unoglo6ulin can 6loc$ the da%aging anti6odies that %a' contri6ute to #uillain:Barre s'ndro%e. (igh:dose i%%unoglo6ulin thera2' <!,!g= is another treat%ent used to reduce the se)erit' and length o- #uillain:Barre s'%2to%s. !n this case, the i%%unoglo6ulins are added to the 6lood in large @uantit', 6loc$ing the anti6odies that cause in-la%%ation. Other treat%ents are directed at 2re)enting co%2lications. Blood thinners %a' 6e used to 2re)ent 6lood clots. !- the dia2hrag% is *ee$, 6reathing su22ort or e)en a 6reathing tu6e and )entilator %a' 6e needed. Pain is treated aggressi)el' *ith anti:in-la%%ator' %edicines and narcotics, i- needed. Pro2er 6od' 2ositioning or a -eeding tu6e %a' 6e used to 2re)ent cho$ing during -eeding i- the %uscles -or s*allo*ing are *ea$. !ntensi)e su22orti)e care 13 Plas%a2heresis or !, i%%une glo6ulin . Each o- these treat%ents is e@uall' e--ecti)e. Mi?ing the treat%ents or ad%inistering one a-ter the other is no %ore e--ecti)e than using either %ethod alone. O-ten 6e-ore reco)er' 6egins, caregi)ers %a' need to %anuall' %o)e 'our ar%s and legs to hel2 $ee2 'our %uscles -le?i6le and strong. A-ter reco)er' has 6egun, 'ouCll li$el' need 2h'sical thera2' to hel2 regain strength and 2ro2er %o)e%ent so that 'ouCll 6e a6le to -unction on 'our o*n. Jou %a' need training *ith ada2ti)e de)ices, such as a *heelchair or 6races, to gi)e 'ou %o6ilit' and sel-:care s$ills. #ifestyle -easures ,o" to #i!e "it% &uillain 'arre Syndrome) !nstructions Ste2 + 8ind a good 2h'sical thera2' 2rogra% -ro% *hich 'ou can learn s2eci-ic iso%etric, isotonic and resistance e?ercises to re6uild *ea$ened %uscles. Jou %a' do these e?ercises on an out2atient 6asis and continue the% at ho%e. Re%e%6er to 2ace 'oursel- and get ade@uate rest, as -atigue is to 6e e?2ected *ith #uillain:Barre S'ndro%e. Ste2 . E?2lore occu2ational thera2' o2tions. Changes in 'our ho%e en)iron%ent can aid in 'our reco)er' 6' %a$ing it easier -or 'ou to 6athe, dress and 2re2are %eals *hile 'our %uscles return to nor%al le)els o- strength. Ste2 / Manage residual 2ain in the 6ac$, legs and -eet *ith %edication as needed. #a6a2entin and car6a%aze2ine are o-ten 2rescri6ed to relie)e #uillain:Barre S'ndro%e related 2ain. Both o- these %edications are anticon)ulsants and %a' cause -atigue and dizziness in so%e 2eo2le. 14 Ste2 1 Bear co%-orta6le shoes and soc$s to hel2 soothe 2ain and 6urning -ro% neuro2ath' in the -eet. !ns2ect 'our -eet o-ten to 6e sure there are no cuts or 6listers that 'ou %a' not ha)e noticed. Ste2 3 8ollo* a health' eating 2lan *ith -resh, seasonal -ruits and )egeta6les , lean %eat and -ish, *hole grains and 2lent' o- color-ul salads. Eating *ell %a' hel2 'ou to sustain 'our energ' and can 6oost 'our %ood. Ste2 4 See$ e%otional su22ort to co2e *ith -eelings o- de2ression and an?iet' that are 2art o- li)ing *ith #uillain:Barre S'ndro%e. &iscuss antide2ressant %edication *ith 'our doctor i- 'ou are ha)ing trou6le *ith acti)ities necessar' -or dail' li)ing. Ste2 5 Connect *ith others *ho are learning to li)e *ith #uillain:Barre S'ndro%e in -oru%s online. See the Resources section 6elo* -or lin$s. ,o" to Reogni3e t%e Sym+toms of &uillain4'arre Syndrome) !nstructions Ste2 + Batch -or earl' s'%2to%s li$e tingling or ru66er' sensations in 'our -eet and legs. !n %an' cases, #uillain:Barre S'ndro%e co%es on ra2idl', 6eginning in the lo*er 2art o- the 6od' and cli%6ing to the ar%s and u22er torso *ithin hours. Tingling around the %outh is co%%on as the s'%2to%s ascend. Ste2 . "ote an' di--icult' *ith -acial %uscles or %o)e%ent, such as trou6le %o)ing 'our e'es, slo* s2eech and 2ro6le%s che*ing or s*allo*ing. 15 Ste2 / Assess 6oth sides o- 'our 6od'. #uillain:Barre S'ndro%e a--ects 6oth sides, unli$e a stro$e. Stro$es generall' 2aral'ze onl' one side. Ste2 1 Test 'our re-le?es. #uillain:Barre S'ndro%e di%inishes the re-le? res2onse in the legs -irst. So%e 2eo2le also lose -eeling in their e?tre%ities. Ste2 3 Chec$ 'our heart rate and 6lood 2ressure . Both %a' dro2 *ith #uillain:Barre S'ndro%e. Ste2 4 E)aluate and re2ort an' changes in 6ladder or 6o*el -unction. #uillain:Barre S'ndro%e i%2acts the %uscles that control 6ladder and intestinal -unction. Ste2 5 Monitor 'our 6reathing, and get hel2 at once i- 6reathing see%s shallo*. #uillain: Barre S'ndro%e can *orsen )er' ra2idl' and s2read to the %uscles that control 'our 6reathing. Man' 2eo2le *ith the s'ndro%e are te%2oraril' 2laced on )entilators in order to 6reathe. Ste2 9 Re)ie* 'our recent %edical histor'. Although scientists ha)en0t disco)ered a single cause -or #uillaine:Barre S'ndro%e, %an' cases are lin$ed *ith recent 6acterial or )iral in-ections , )accinations or surgeries. !n-ection *ith ca%2'lo6acter, a 6acteria -ound in undercoo$ed -ood, es2eciall' 2oultr', %a' trigger #uillaine:Barre S'ndro%e. Ste2 ; Pa' attention to unusual or se)ere lo*er 6ac$ 2ain, *hich can signal #uillain: Barre S'ndro%e. 16 .N.TO-5 .N0 P,5SIO#O&5 T,E NER6O7S S5STE- Ty+ial Struture of a Ner!e Cell The ner)ous s'ste% is di)ided into theI +eri+%eral ner!ous system <PNS= entral ner!ous system <CNS= 17 A ner)e cell <neuron= consists o- a large cell 6od' and ner)e -i6ersKone elongated e?tension <a?on= -or sending i%2ulses and usuall' %an' 6ranches <dendrites= -or recei)ing i%2ulses. Each large a?on is surrounded 6' oligodendroc'tes in the 6rain and s2inal cord and 6' Sch*ann cells in the 2eri2heral ner)ous s'ste%. The %e%6ranes o- these cells consist o- a -at <li2o2rotein= called %'elin. The %e%6ranes are *ra22ed tightl' around the a?on, -or%ing a %ultila'ered sheath. This %'elin sheath rese%6les insulation, such as that around an electrical *ire. "er)e i%2ulses tra)el %uch -aster in ner)es *ith a %'elin sheath than in those *ithout one. !- the %'elin sheath o- a ner)e is da%aged, ner)e trans%ission slo*s or sto2s The PNS consists o- sensor' neurons running -ro% sti%ulus rece2tors that in-or% the C"S o- the sti%uli %otor neurons running -ro% the C"S to the %uscles and glands : called e--ectors : that ta$e action. The CNS consists o- the s2inal cord and the 6rain T,E PERIP,ER.# NER6O7S S5STE- IN 8OC7S !n the 2eri2heral ner)ous s'ste%, neurons can 6e -unctionall' di)ided in three *a'sI +. Sensory 1afferent2 : carr' in-or%ation !"TO the central ner)ous s'ste% -ro% sense organs or motor 1efferent2 : carr' in-or%ation a*a' -ro% the central ner)ous s'ste% <-or %uscle control=. .. Cranial : connects the 6rain *ith the 2eri2her' or s+inal : connects the s2inal cord *ith the 2eri2her'. /. Somati : connects the s$in or %uscle *ith the central ner)ous s'ste% or !iseral : connects the internal organs *ith the central ner)ous s'ste% The +eri+%eral ner!ous system is su6di)ided into the sensor':so%atic ner)ous s'ste% and the 18 autono%ic ner)ous s'ste% T%e Sensory4Somati Ner!ous System The sensor':so%atic s'ste% consists o-I +. 2airs o- cranial ner)es and /+ 2airs o- s2inal ner)es. T%e Cranial Ner!es Ner!es Ty+e 8untion I Ol-actor' sensor' ol-action <s%ell= II O2tic sensor' )ision <Contain /9H o- all the a?ons connecting to the 6rain.= III Oculo%otor %otorP e'elid and e'e6all %uscles I6 Trochlear %otorP e'e6all %uscles 6 Trige%inal %i?ed Sensor'I -acial and %outh sensation MotorI che*ing 6I A6ducens %otorP e'e6all %o)e%ent 6II 8acial %i?ed Sensor'I taste MotorI -acial %uscles and sali)ar' glands 6III Auditor' sensor' hearing and 6alance I9 #losso2har'ngeal %i?ed Sensor'I taste MotorI s*allo*ing 9 ,agus %i?ed %ain ner)e o- the 2aras'%2athetic ner)ous s'ste% <P"S= 9I Accessor' %otor s*allo*ingE %o)ing head and shoulder 9II ('2oglossal %otorP tongue %uscles P"oteI These do contain a -e* sensor' neurons that 6ring 6ac$ signals -ro% the %uscle s2indles in the %uscles the' control. 19 T%e S+inal Ner!es All o- the s2inal ner)es are N%i?edNE that is, the' contain 6oth sensor' and %otor neurons. All our conscious a*areness o- the e?ternal en)iron%ent and all our %otor acti)it' to co2e *ith it o2erate through the sensor':so%atic di)ision o- the P"S. T%e .utonomi Ner!ous System The autono%ic ner)ous s'ste% consists o- sensor' neurons and %otor neurons that run 6et*een the central ner)ous s'ste% <es2eciall' the h'2othala%us and %edulla o6longata= and )arious internal organs such as theI heart lungs )iscera glands <6oth e?ocrine and endocrine= !t is res2onsi6le -or %onitoring conditions in the internal en)iron%ent and 6ringing a6out a22ro2riate changes in the%. The contraction o- 6oth s%ooth %uscle and cardiac %uscle is controlled 6' %otor neurons o- the autono%ic s'ste%. The actions o- the autono%ic ner)ous s'ste% are largel' in)oluntar' <in contrast to those o- the sensor':so%atic s'ste%=. !t also di--ers -ro% the sensor':so%atic s'ste% is using t*o grou2s o- %otor neurons to sti%ulate the e--ectors instead o- one. The -irst, the 2reganglionic neurons, arise in the C"S and run to a ganglion in the 6od'. (ere the' s'na2se *ith 2ostganglionic neurons, *hich run to the e--ector organ <cardiac %uscle, s%ooth %uscle, or a gland=. The autono%ic ner)ous s'ste% has t*o su6di)isions, the s'%2athetic ner)ous s'ste% and the 2aras'%2athetic ner)ous s'ste%. T%e Sym+at%eti Ner!ous System The 2reganglionic %otor neurons o- the s'%2athetic s'ste% arise in the s2inal cord. The' 2ass into s'%2athetic ganglia *hich are organized into t*o chains that run 2arallel to and on either side o- the s2inal cord. The 2reganglionic neuron %a' do one o- three things in the s'%2athetic ganglionI 20 s'na2se *ith 2ostganglionic neurons *hich then reenter the s2inal ner)e and ulti%atel' 2ass out to the s*eat glands and the *alls o- 6lood )essels near the sur-ace o- the 6od'. 2ass u2 or do*n the s'%2athetic chain and -inall' s'na2se *ith 2ostganglionic neurons in a higher or lo*er ganglion lea)e the ganglion 6' *a' o- a cord leading to s2ecial ganglia <e.g. the solar 2le?us= in the )iscera. (ere it %a' s'na2se *ith 2ostganglionic s'%2athetic neurons running to the s%ooth %uscular *alls o- the )iscera. (o*e)er, so%e o- these 2reganglionic neurons 2ass right on through this second ganglion and into the adrenal %edulla. (ere the' s'na2se *ith the highl':%odi-ied 2ostganglionic cells that %a$e u2 the secretor' 2ortion o- the adrenal %edulla. The neurotrans%itter o- the 2reganglionic s'%2athetic neurons is acet'lcholine <ACh=. !t sti%ulates action 2otentials in the 2ostganglionic neurons. The neurotrans%itter released 6' the 2ostganglionic neurons is noradrenaline <also called nore2ine2hrine=. The action o- noradrenaline on a 2articular gland or %uscle is e?citator' is so%e cases, inhi6itor' in others. <At e?citator' ter%inals, ATP %a' 6e released along *ith noradrenaline.= The release o- noradrenaline sti%ulates heart6eat raises 6lood 2ressure dilates the 2u2ils dilates the trachea and 6ronchi sti%ulates the con)ersion o- li)er gl'cogen into glucose shunts 6lood a*a' -ro% the s$in and )iscera to the s$eletal %uscles, 6rain, and heart inhi6its 2eristalsis in the gastrointestinal <#!= tract inhi6its contraction o- the 6ladder and rectu% and, at least in rats and %ice, increases the nu%6er o- AMPA rece2tors in the hi22oca%2us and thus increases long:ter% 2otentiation <LTP=. !n short, sti%ulation o- the s'%2athetic 6ranch o- the autono%ic ner)ous s'ste% 2re2ares the 6od' -or e%ergenciesI -or N-ight or -lightN <and, 2erha2s, enhances the %e%or' o- the e)ent that triggered the res2onse=. Acti)ation o- the s'%2athetic s'ste% is @uite general 6ecause 21 a single 2reganglionic neuron usuall' s'na2ses *ith %an' 2ostganglionic neuronsE The release o- adrenaline -ro% the adrenal %edulla into the 6lood ensures that all the cells o- the 6od' *ill 6e e?2osed to s'%2athetic sti%ulation e)en i- no 2ostganglionic neurons reach the% directl'. T%e Parasym+at%eti Ner!ous System The %ain ner)es o- the 2aras'%2athetic s'ste% are the tenth cranial ner)es, the )agus ner)es. The' originate in the %edulla o6longata. Other 2reganglionic 2aras'%2athetic neurons also e?tend -ro% the 6rain as *ell as -ro% the lo*er ti2 o- the s2inal cord. Each 2reganglionic 2aras'%2athetic neuron s'na2ses *ith 7ust a -e* 2ostganglionic neurons, *hich are located near : or in : the e--ector organ, a %uscle or gland. Acet'lcholine <ACh= is the neurotrans%itter at all the 2re: and %an' o- the 2ostganglionic neurons o- the 2aras'%2athetic s'ste%. (o*e)er, so%e o- the 2ostganglionic neurons release nitric o?ide <"O= as their neurotrans%itter. Paras'%2athetic sti%ulation causes slo*ing do*n o- the heart6eat lo*ering o- 6lood 2ressure constriction o- the 2u2ils increased 6lood -lo* to the s$in and )iscera 2eristalsis o- the #! tract !n short, the 2aras'%2athetic s'ste% returns the 6od' -unctions to nor%al a-ter the' ha)e 6een altered 6' s'%2athetic sti%ulation. !n ti%es o- danger, the s'%2athetic s'ste% 2re2ares the 6od' -or )iolent acti)it'. The 2aras'%2athetic s'ste% re)erses these changes *hen the danger is o)er. The )agus ner)es also hel2 $ee2 in-la%%ation under control. !n-la%%ation sti%ulates near6' sensor' neurons o- the )agus. Bhen these ner)e i%2ulses reach the %edulla o6longata, the' are rela'ed 6ac$ along %otor -i6ers to the in-la%ed area. The acet'lcholine -ro% the %otor neurons su22resses the release o- in-la%%ator' c'to$ines, e.g., tu%or necrosis -actor <T"8=, -ro% %acro2hages in the in-la%ed tissue. Although the autono%ic ner)ous s'ste% is considered to 6e in)oluntar', this is not entirel' true. A certain a%ount o- conscious control can 6e e?erted o)er it as has long 6een de%onstrated 6' 2ractitioners o- Joga and Qen Buddhis%. &uring their 2eriods o- %editation, these 2eo2le are clearl' a6le to alter a nu%6er o- autono%ic -unctions including heart rate and the rate o- o?'gen consu%2tion. These changes are 22 not si%2l' a re-lection o- decreased 2h'sical acti)it' 6ecause the' e?ceed the a%ount o- change occurring during slee2 or h'2nosis. I--7NE S5STE- The i%%une s'ste% is co%2osed o- %an' interde2endent cell t'2es that collecti)el' 2rotect the 6od' -ro% 6acterial, 2arasitic, -ungal, )iral in-ections and -ro% the gro*th o- tu%or cells. Man' o- these cell t'2es ha)e s2ecialized -unctions. The cells o- the i%%une s'ste% can engul- 6acteria, $ill 2arasites or tu%or cells, or $ill )iral:in-ected cells. O-ten, these cells de2end on the T hel2er su6set -or acti)ation signals in the -or% o- secretions -or%all' $no*n as c'to$ines, l'%2ho$ines, or %ore s2eci-icall' interleu$ins. T%e Organs of t%e Immune System 'one -arro" :: All the cells o- the i%%une s'ste% are initiall' deri)ed -ro% the 6one %arro*. The' -or% through a 2rocess called he%ato2oiesis. &uring he%ato2oiesis, 6one %arro*:deri)ed ste% cells di--erentiate into either %ature cells o- the i%%une s'ste% or into 2recursors o- cells that %igrate out o- the 6one %arro* to continue their %aturation else*here. The 6one %arro* 2roduces B cells, natural $iller cells, granuloc'tes and i%%ature th'%oc'tes, in addition to red 6lood cells and 2latelets. T%ymus 44 The -unction o- the th'%us is to 2roduce %ature T cells. !%%ature th'%oc'tes, also $no*n as 2roth'%oc'tes, lea)e the 6one %arro* and %igrate into the th'%us. Through a re%ar$a6le %aturation 2rocess so%eti%es re-erred to as th'%ic education, T cells that are 6ene-icial to the i%%une s'ste% are s2ared, *hile those T cells that %ight e)o$e a detri%ental autoi%%une res2onse are eli%inated. The %ature T cells are then released into the 6loodstrea%. S+leen :: The s2leen is an i%%unologic -ilter o- the 6lood. !t is %ade u2 o- B cells, T cells, %acro2hages, dendritic cells, natural $iller cells and red 6lood cells. !n addition to ca2turing -oreign %aterials <antigens= -ro% the 6lood that 2asses through the s2leen, %igrator' %acro2hages and dendritic cells 6ring antigens to the s2leen )ia the 6loodstrea%. An i%%une res2onse is initiated *hen the %acro2hage or dendritic cells 2resent the antigen to the a22ro2riate B or T cells. This organ can 6e thought o- as an i%%unological con-erence center. !n the s2leen, B cells 6eco%e acti)ated and 2roduce large a%ounts o- anti6od'. Also, old red 6lood cells are destro'ed in the s2leen. #ym+% Nodes :: The l'%2h nodes -unction as an i%%unologic -ilter -or the 6odil' -luid $no*n as l'%2h. L'%2h nodes are -ound throughout the 6od'. Co%2osed %ostl' o- T cells, B cells, dendritic cells and %acro2hages, the nodes drain -luid -ro% %ost o- our tissues. Antigens are -iltered out o- the l'%2h in the l'%2h node 6e-ore returning the l'%2h to the circulation. !n a si%ilar -ashion as the s2leen, the %acro2hages and 23 dendritic cells that ca2ture antigens 2resent these -oreign %aterials to T and B cells, conse@uentl' initiating an i%%une res2onse.
T%e Cells of t%e Immune System T4Cells :: T l'%2hoc'tes are usuall' di)ided into t*o %a7or su6sets that are -unctionall' and 2henot'2icall' <identi-ia6l'= di--erent. The T hel2er su6set, also called the C&1R T cell, is a 2ertinent coordinator o- i%%une regulation. The %ain -unction o- the T hel2er cell is to aug%ent or 2otentiate i%%une res2onses 6' the secretion o- s2ecialized -actors that acti)ate other *hite 6lood cells to -ight o-- in-ection. Another i%2ortant t'2e o- T cell is called the T $illerLsu22ressor su6set or C&9R T cell. These cells are i%2ortant in directl' $illing certain tu%or cells, )iral:in-ected cells and so%eti%es 2arasites. The C&9R T cells are also i%2ortant in do*n:regulation o- i%%une res2onses. Both t'2es o- T cells can 6e -ound throughout the 6od'. The' o-ten de2end on the secondar' l'%2hoid organs <the l'%2h nodes and s2leen= as sites *here acti)ation occurs, 6ut the' are also -ound in other tissues o- the 6od', %ost cons2icuousl' the li)er, lung, 6lood, and intestinal and re2roducti)e tracts. Natural Killer Cells 4: "atural $iller cells, o-ten re-erred to as " cells, are si%ilar to the $iller T cell su6set <C&9R T cells=. The' -unction as e--ector cells that directl' $ill certain tu%ors such as %elano%as, l'%2ho%as and )iral:in-ected cells, %ost nota6l' her2es and c'to%egalo)irus:in-ected cells. " cells, unli$e the C&9R <$iller= T cells, $ill their 24 targets *ithout a 2rior Ncon-erenceN in the l'%2hoid organs. (o*e)er, " cells that ha)e 6een acti)ated 6' secretions -ro% C&1R T cells *ill $ill their tu%or or )iral:in-ected targets %ore e--ecti)el'. ' Cells 44 The %a7or -unction o- B l'%2hoc'tes is the 2roduction o- anti6odies in res2onse to -oreign 2roteins o- 6acteria, )iruses, and tu%or cells. Anti6odies are s2ecialized 2roteins that s2eci-icall' recognize and 6ind to one 2articular 2rotein that s2eci-icall' recognize and 6ind to one 2articular 2rotein. Anti6od' 2roduction and 6inding to a -oreign su6stance or antigen, o-ten is critical as a %eans o- signaling other cells to engul-, $ill or re%o)e that su6stance -ro% the 6od'. &ranuloytes or Polymor+%onulear 1P-N2 #eu*oytes :: Another grou2 o- *hite 6lood cells is collecti)el' re-erred to as granuloc'tes or 2ol'%or2honuclear leu$oc'tes <PM"s=. #ranuloc'tes are co%2osed o- three cell t'2es identi-ied as neutro2hils, eosino2hils and 6aso2hils, 6ased on their staining characteristics *ith certain d'es. These cells are 2redo%inantl' i%2ortant in the re%o)al o- 6acteria and 2arasites -ro% the 6od'. The' engul- these -oreign 6odies and degrade the% using their 2o*er-ul enz'%es. -aro+%ages 4: Macro2hages are i%2ortant in the regulation o- i%%une res2onses. The' are o-ten re-erred to as sca)engers or antigen:2resenting cells <APC= 6ecause the' 2ic$ u2 and ingest -oreign %aterials and 2resent these antigens to other cells o- the i%%une s'ste% such as T cells and B cells. This is one o- the i%2ortant -irst ste2s in the initiation o- an i%%une res2onse. Sti%ulated %acro2hages e?hi6it increased le)els o- 2hagoc'tosis and are also secretor'. 0endriti Cells 44 Another cell t'2e, addressed onl' recentl', is the dendritic cell. &endritic cells, *hich also originate in the 6one %arro*, -unction as antigen 2resenting cells <APC=. !n -act, the dendritic cells are %ore e--icient a2cs than %acro2hages. These cells are usuall' -ound in the structural co%2art%ent o- the l'%2hoid organs such as the th'%us, l'%2h nodes and s2leen. (o*e)er, the' are also -ound in the 6loodstrea% and other tissues o- the 6od'. !t is 6elie)ed that the' ca2ture antigen or 6ring it to the l'%2hoid organs *here an i%%une res2onse is initiated. Un-ortunatel', one reason *e $no* so little a6out dendritic cells is that the' are e?tre%el' hard to isolate, *hich is o-ten a 2rere@uisite -or the stud' o- the -unctional @ualities o- s2eci-ic cell t'2es. O- 2articular issue here is the recent -inding that dendritic cells 6ind high a%ount o- (!,, and %a' 6e a reser)oir o- )irus that is trans%itted to C&1R T cells during an acti)ation e)ent. 25 An ani%al0s immune system 2rotects its 6od' -ro% intrudersI 6acteria, )iruses, 2arasites, cancer cells, etc. An i%%une s'ste% is 2resent in se)eral ani%al grou2s, es2eciall' *ithin the )erte6rates. Ani%als ha)e 6oth non:s2eci-ic and s2eci-ic de-ense %echanis%s to -ight in)aders. Be *ill 6e -ocusing on the hu%an i%%une s'ste%. Non4s+eifi defense me%anisms *or$ against a *ide )ariet' o- in)aders. These de-ense %echanis%s include the 6arrier -or%ed 6' our s*inE %emials in 2ers2iration, s$in oil, sali)a, tears, etc.E the %airs in our nostrilsE the iliary esalator <the cilia and %ucus that clean out dust and de6ris -ro% our lungs and trachea= in our res2irator' tractsE the inflammatory res+onse *hich is the dilation o- 6lood )essels and accu%ulation o- BBCs at the site o- an in7ur' <the signs o- *hich are that the area is red, hot, and s*ollen=E and fe!er, a raised 6od' te%2erature to inhi6it the gro*th o- 2athogens. "ote that a -e)er is caused 6' 'our 6od' to inhi6it the gro*th o- 6acteria, etc., not 6' the Sger%sT the%sel)es, per se. S+eifi defense me%anisms are e--ecti)e against s2eci-ic 2athogens. This in)ol)es )arious BBCs called lym+%oytes or leu*oytes. There are se)eral $inds o- BBCs in)ol)ed in the i%%une s'ste%, all o- *hich originate in the 6one %arro*. #eu*emia is a cancer o- the 6one %arro*, thus it t'2icall' is treated 6' $illing all o- the 2erson0s 6one %arro*. Un-ortunatel', this lea)es the 2erson *ith no i%%une s'ste%, so <s=he %ust 6e e?tre%el' care-ul during that ti%e to a)oid all 2ossi6le 2athogens. There are t*o %ain t'2es o- s2eci-ic de-ense %echanis%s in)ol)ed in the i%%une s'ste%. The ell4mediated immune system consists o- T4ells *hich originate in the 6one %arro*, 6ut go to the T%ymus to -inish their de)elo2%ent. 26 T:cells are highl':s2ecialized cells in the 6lood and l'%2h to -ight 6acteria, )iruses, -ungi, 2rotozoans, cancer, etc. *ithin host cells and react against -oreign %atter such as organ trans2lants. There are three $inds o- T:cells. Cytoto:i T4ells directl' $ill in)aders. ,el+er T4ells aid B and other T:cells to do their 7o6s, and (!, li)es in and $ills the%. Su++ressor T4 ells su22ress the acti)ities o- B: and other T:cells so the' don0t o)erreact. Allerg' in7ections are su22osed to increase the nu%6er o- su2ressor T:cells to %a$e the 2erson less sensiti)e to allergens. Immunity is the a6ilit' to Sre%e%6erT -oreign su6stance 2re)iousl' encountered and react again, 2ro%2tl'. There are t*o $inds o- i%%unit'I ati!e immunity, *hen the 6od' is sti%ulated to 2roduce its o*n anti6odies, and +assi!e immunity, *here the anti6odies co%e -ro% outside the 2erson0s 6od'. Acti)e i%%unit' is usuall' 2er%anent, and can 6e induced due to actual illness or )accination. Passi)e i%%unit' is not 2er%anent 6ecause the anti6odies are introduced -ro% outside the 6od', thus the B: cells ne)er SlearnT ho* to %a$e the%. So%e e?a%2les o- 2assi)e i%%unit' include anti6odies 2assed across the 2lacenta and in %il$ -ro% a %other to her 6a6', so%e tra)elers0 shots, and the Rhoga% shots *e *e discussed earlier this @uarter. Because anti6odies are onl' 2rotein, the' don0t last )er' long and %ust 6e re2laced i- the i%%unit' is to continue. Patient ,ealt% ,istory ,os+ital: Caraga Regional (os2ital 27 Room Number: Pediatric Bard, Miscellaneous Case number: +3:>5:34 Name of t%e Patient: Patient R .geI +4 'ears old 0ate of 'irt%I Octo6er .+, +;;/ Ci!il StatusI Single Religion: !glesia 8ili2ina !nde2endiente ,ig%est Eduational .ttainmentI (igh School le)el Ou+ationI "O"E ,ome .ddressI Es2eranza, Loreto, &inagat !sland, Surigao del "orte ,ealt% Care 8inaning and 7sual Soure of medial CareI 8a%il' inco%e -ode of .dmission: carried 6' his -ather 0ate of .dmission: Se2te%6er .3, .>>; Time of .dmission: +>I.3 a% 6ital Signs u+on .dmission: Te%2eratureI /4.5Cc Pulse RateI 9462% Res2irator' RateI +9c2% Blood PressureI +.>L5> %%(g
C%ief Com+lain: Present condition noted as sudden onset o- *ea$ness o- le-t lo*er e?tre%ities -or al%ost / *ee$s, then a-ter right lo*er e?tre%ities a *ee$ a-ter
.dmitting 0iagnosis: #uillain BarreC S'ndro%e 8inal 0iagnosis: #uillain BarreC S'ndro%e .ttending P%ysiian: &r. Asodisen <-ro% Se2te%6er .3:/>= &r. Moleta < -ro% Octo6er +:4= 28 Name of Informant: PatientCs %other 0ate of 0is%argeI Octo6er 4, .>>; Condition u+on 0is%arge: !%2ro)ed Soure of Stability of 0ata gat%ered: Pri%ar' source <2atient=, Secondar' Source <2atientCs SO and chart= I'$ U ++9 ++9 :+> R+> +.; : +.9 l6s 2atient is onl' +>/.4+ l6s, there-ore 2atient is under*eight '-I U *eight <in $gs= L height <in %= . U 15 $g L <+.393 %= . U 15 L ..3+ U +9.5. 2atient0s BM! is nor%al .. ,istory of Present Illness 29 On the . nd *ee$ o- August .>>;, 2atient stated that he e?2erienced a6do%inal cra%2s and diarrhea *ith *ater' stool characterized *ith 'ello*:green in color *hich lasted -or . da's a-ter he had eaten $inila*. A-ter t*o *ee$s, 2atient started to co%2lain a tingling sensation or so%ething li$e an electric current on his -eet and cli%6ed u2 to the thighs and a little nu%6. Patient sus2ected that the cause o- this *as the usual 6athing o- legs a-ter ha)ing a *al$ -or a22ro?i%atel' 1$%s e)er'da' going to school and 6ac$ ho%e. On the . nd *ee$, 2atient e?2erienced *ea$ness, es2eciall' on his le-t leg that %ade hi% not a6le to *al$ed and had li%ited range o- %otion. On the -ollo*ing da's, his condition *orsens. (e -elt *ea$ness acco%2anied *ith tingling sensation *hich o-ten attac$ earl' in the %orning and late a-ternoon and a cou2le o- ti%e during hour slee2 as clai%ed 6' the 2atient. The da' a-ter, nu%6ness on lo*er e?tre%ities *ith uncontrolled %o)e%entsLtre%ors occurs *hich last a6out ten %inutes. At that ti%e, he couldn0t sit on his o*n and *hen he did sit u2 *ith assistance as *ell as in his eli%ination 2ur2oses. (e -elt li$e an egg as stated 6' the 2atient. Patient0s -a%il' sought ad)ice -ro% the local S%anghihilotT *ho %assaged the a--ected area *ith his o*n:%ade %i?ture o- her6s. The latter 6elie)ed that 2atient condition is caused 6' S6u'ag sa eng$antoT. The' also as$ed hel2 -ro% a S%anta'ho2a'T *ho ga)e the sa%e i%2ression. (is %other -ollo*ed the instructions o- the said 2ersons such as soa$ing his -eet *ith Snilagang sa%6ongT e)er' %orning and at night 6e-ore slee2ing. (os2italization *as not 2ossi6le during the said s2an o- ti%e 6ecause o- -inancial constraints. One da' 2rior to hos2italization, our 2atient *as seen 6' his %other cr'ing on the -loor o- their sala. Patient stated that S gusto na na$o %ag2ahos2ital, nahadlo$ na a$o 6asin dili na a$o %a$ala$a* 2ag6ali$. That incident 2ro%2ted his %other to 6ring hi% to Loreto &istrict (os2ital that da' 6ut *as re-erred directl' to Caraga Regional (os2ital -or -urther assess%ent and %anage%ent. Patient *as ad%itted to Caraga Regional (os2ital last Se2te%6er .3, .>>; at e?actl' +>I.3 a% -or chie- co%2laintsI noted as sudden onset o- *ea$ness o- le-t lo*er e?tre%ities -or al%ost / *ee$s, then a-ter right lo*er e?tre%ities a *ee$ a-ter
U2on con-ine%ent, the doctor 2rescri6ed the -ollo*ingI
!,8 &3!MB+>> V .3 gttsL%in
,ita%in B co%2le? + ca2 O&
('drocortisone +>>%g !,TT @9
> La6orator' tests *ere also ordered 6' the attending 2h'sician such asI (e%atolog' Electrol'tes Urinal'sis 30 '. Past ,ealt% ,istory C%ild%ood Illness Patient0s %other clai%ed that his son donCt ha)e an' childhood illnesses li$e %u%2s, chic$en2o?, ru6ella and 2ertussis, etc. (e e?2erienced diarrhea last Januar' .>>; *hich lasted -or al%ost . and a hal- da's characterized *ith *ater' stool 'ello*ish:green in color. A-ter that incidence he su--ered diarrhea again last Ma' .>>; *ith the sa%e duration and -eature 6ut he *as not a6le to hos2italized. Patient e?2erienced + *ee$ -e)er acco%2anied *ith 2roducti)e cough *ith thic$ 'ello* s2utu% on the last *ee$ o- Jul' .>>;.
Immuni3ation PatientCs %other clai%ed that onl' BC# had 6een i%%unized to her son since health center is -ar a*a' -ro% their house.
,istory of ,os+itali3ation Patient has no histor' o- hos2italizationE in -act this is his -irst ti%e o- 6eing ad%itted in the hos2ital.
Surgial ,istory Patient clai%ed that he did not undergo an' surgical 2rocedure.
.idents and In;uries A *ee$ 6e-ore he con-ined at Caraga Regional (os2ital, he stated that *hen he *as ha)ing an e?ercise earl' in the %orning near6' shore a22ro?i%atel' 5:+> %eters a*a' -ro% their house suddenl' he -elt *ea$ness on his legs and tingling sensation acco%2anied 6' tre%ors that %ade hi% -all do*n to the ground. (e *as tr'ing to drag hi%sel- going to their house that causes a6rasion and *ounds on his legs, le-t -oot, right and le-t $nees. Until no* his *ounds are in the healing 2rocess, his %other used her6al 2lants li$e %alunga' to treat his *ounds.
.llergi and Ty+e of Reation Patient clai%ed that he donCt ha)e an' -ood allerg' or drug allerg'.
8amily ,ealt% ,istory Patient *as the eldest o- -i)e. (is %other is 1/ 'ears old and in good condition. (is -ather is 34 'ears old currentl' su--ering -ro% cough -or al%ost t*o *ee$s and has arthritis. The usual sic$ness o- his si6lings e?2erienced, *ere colds and cough *hich can 6e relie)ed 6' o)er the counter drugs such as 6iogesic, neoze2, car6ocisteine and 2araceta%ol. The grand%otherL-ather in the %other side are ali)e *ith no underl'ing illness. The grand-atherL%other in the -ather side *ere alread' deceased. (is grand-ather died last +;;9 according to the% it *as 7ust sudden onset o- s*elling on his lo*er e?tre%ities and a *ee$ a-ter the u22er e?tre%ities and de)elo2ed into entire 6od'. (e *as not hos2italized and *as not diagnosed, in -act according to 31 their 6elie- and ru%ors his grand-ather *as Nna 6arangN. A-ter one %onth o- su--ering -ro% generalized s*elling ha *as died l'ing on the 6ed unnoticel'. A-ter 5 'ears, that is .>>3 his grand%other died as clai%ed 6' the 2atientCs %other, she died *ith the sa%e case to her hus6and 6ecause o- generalized s*elling 6ut 2atientCs %other clai%ed that she canCt recall i- *hat ha22ened to her %other:in:la* since the' *ere a2art -ro% here *hen that ti%e ha22ened, all she $no*s is that a-ter one %onth also o- su--ering -ro% s*elling she died. Personal ,ealt% ,istory #ifestyle <. Personal ,abit 'efore ,os+itali3ation Patient is a non:s%o$er and non:drin$er and donCt e)en used har%-ul drugs. Be-ore he *as con-ined at hos2ital, he alread' -elt *ea$ness on his legs that %ade hi% 7ust sta' on their house. (e 7ust *atched *o*o*ee and listening %usic and *hen he got 6ored he 7ust sit near6' the *indo* and 7ust loo$ed around to his -riends outside since he canCt *al$ and 7oin *ith the%. (e 7ust stud' his lesson 6' hi%sel- since he sto2 going to school -or al%ost / *ee$s 6ecause o- his condition. 0uring ,os+itali3ation Since 2atient *as *ea$ and canCt %o)ed his legs , he 7ust lied on the 6ed and so%eti%es sit 6ut still his legs *ere in straight and -lat 2osition. Patient has li%ited %o)e%ent that %ade hi% unco%-orta6le. (e 7ust slee2 and so%eti%es a*a$e i- tingling sensation occur. (e also used to ha)e little con)ersation to his -a%il'. (e 7ust $ee2 on s%iling *hene)er there *ere 2eo2le loo$ed at hi%.
2. 0iet 'efore ,os+itali3ation Patient t'2ical -ood is -ish since the' li)ed near6' the sea and his -ather occu2ation is -ishing and also )egeta6les. Patient eats his %eals /? a da' 6ut so%eti%es he doesn0t *ant to eat in the 6rea$-ast. Patient drin$s 9:+> glasses o- *ater a da' he donCt ha)e an' s2ecial diet or an' -ood restriction. Patient *as -ond o- eating S$inila*T *ith )inegar than coo$ed. (e eats / large %eals a da' and drin$s 3:4 glasses o- *ater. Patient is -ond o- eating ra* egg *ith salt. (e eats 7un$ -oods as his snac$s. (e drin$s co--ee and Milo so%eti%es i- it is a)aila6le on their $itchen. 0uring ,os+itali3ation Patient eat the -ood that is 6eing ser)e in the hos2ital 6ut so%eti%es his %other 6u' -ood outside li$e tinolang 6a$a and an' -ood that has sou2. (e also eats -ruits li$e orange, 6anana and %ango. And earl' in the %orning his %other *ill %a$e %il$L%ilo -or hi%. So%eti%es he re-uses to eat 6ecause he -elt -ullness, he drin$ /:1 glasses o- *ater a da'. (e doesn0t ha)e an' order o- -ood restriction or an' s2ecial diet -ro% the dietician 6ut the doctor ordered + 6anana last Se2te%6er .4, .>>;.
32 =. Slee+ and Rest Pattern 'efore ,os+itali3ation Patient usuall' slee2 at 92% and *a$e u2 4a%, 6e-ore the 2resent illness he had no di--iculties in slee2ing, 6ut *hen he started to -elt *ea$ness and tingling sensation he canCt slee2 a22ro2riatel' cause he canCt %o)ed his legs side 6' side. 0uring ,os+itali3ation Patient has di--icult' o- slee2ing and *a$es u2 a nu%6er o- ti%es during hour slee2. (e clai%ed that his not co%-orta6le to slee2 in the hos2ital as *ell as his 2osition in slee2ing, he -elt heCs li$e a dead 2erson l'ing in a straight and -lat 2osition. And so%eti%es heCs %other a*a$en hi% *hen uncontrolled %o)e%ents o- %uscle occur since 2atient couldn0t -elt an' sense. >. Elimination Pattern 'efore ,os+itali3ation Patient urinate /? a da' characterized 6' large a%ount *ith 'ello* in color and de-ecate once a da' characterized 6' scant' a%ount *ith 'ello*ishL6ro*nish in color *ith no histor' o- di--icult' or 2ain in urinating and de-ecating. Patient did not e?2erience consti2ation. Be-ore the 2resent illness , he eli%inate *ith hi%sel- 6ut 6ecause o- his condition he reall' needs assistance -or eli%ination 2ur2oses, usuall' his -ather carried hi% in going to co%-ort roo%. 0uring ,os+itali3ation Patient urinate 1:3? a da', *hen he )oid he 7ust sit on the 6ed and his %other *ill o--er 2lastic container o- the !,8 since he canCt go 6' hi%sel- to the co%-ort roo%. So%eti%es it ta$es /:1 da's 6e-ore he can de-ecate and his -ather carried hi% going to the co%-ort roo%. (is last )oid is scant' and 'ello* in color and his -ecal is hard stool, 'ello*ish in color.
?. .ti!ities of 0aily #i!ing 'efore ,os+itali3ation E)en though 6e-ore hos2italization 2atient has di--icult' on his acti)ities o- dail' li)ing 6ecause o- his condition he cant ta$e a 6ath and dress alone, his %other has 6een al*a's there -or hi% in doing his groo%ing and h'giene as *ell as in his eli%ination and loco%otion, he had li%ited %o)e%ents. The onl' thing he can do -or hi%sel- is 7ust that *hen he eat or holds an' o67ect. (e couldn0t hel2 in household chores unli$e 6e-ore. 0uring ,os+itali3ation Patient doesn0t ha)e an' acti)ities, he 7ust lies on the 6ed. (e clai%ed that he *as 6oredE he *ants to ha)e so%e e?ercise as *hat he usuall' did 6e-ore his condition. (e 7ust has so%e con)ersation *ith his %other and a-ter that he -ined hi%sel- slee2ing and a*a$ens -or a -e* hours.
@. Rereation and ,obbies 33 'efore ,os+itali3ation Patient usual recreation and ho66ies *ere *atching tele)ision and listen dra%a in the radio. (e used to read 2oc$et6oo$s *hen he got 6ored. Be-ore his condition he e?ercised e)er'da' earl' in the %orning and s*i%%ing in the sea. 0uring ,os+itali3ation Patient 7ust lies in the 6ed. Bhen the 2atient is in -ine %ood, he usuall' chatt' and lights u2 *hen he is tal$ing to his )isitorsL2arents. (e al*a's *ar 6eauti-ul s%iles on his -ace des2ite o- his condition.
A. Soial 0ata The 2atient usuall' turns to his 2arents -or su22ort during ti%e o- stress and school 2ro6le% es2eciall' a6out *hat he -elt on his -irst tri%ester o- illness. (e re2orted to his 2arents -or e)er' detailed e)ent that ha22ened to his condition. Patient does not 6elie)e in su2erstitious 6elie- or @uac$ doctors e)en though his 2arent do so. Patient is currentl' stud'ing -irst 'ear high school 6ut e)entuall' sto22ed 6ecause o- his condition.
B. Ou+ational .ti!ity "ot a22lica6le. Patient is still stud'ing. C. En!ironmental 0ata Patient li)ed at Es2eranza, Loreto, &inagat !sland, S&". Their house is located near6' the sea a22ro?i%atel' +>:+. %eters a*a' -ro% their house. Their house is %ade o- *ood and ni2a hut. The' ha)e one sala, roo%, and $itchen and co%-ort roo%. Their house is surrounded *ith 2lants and the' ha)e garden *herein the' 2lant )egeta6les -or their -ood consu%2tion. And also a little chic$en 2oultr' -or their consu%2tion o- eggs. The' ha)e a clean en)iron%ent *here in he can 6reathe -resh air *ith no 2ollution. <D. Psy%ologial 0ata Patient %a7or stressor in li-e *as his condition no*, he *as *orried a6out his legs i- it *ill 6e 6ac$ in nor%al again 6ut des2ite o- his 2ro6le% he *as tr'ing to 6e strong and tend to 6e ha22' -or he 6elie)ed that he *ill 6e cured and nothing is i%2ossi6le *ith #od.
<<. Pattern of ,ealt% Care Patient is a non:%e%6er o- Phil (ealth, #S!S and SSS. Patient0s %other used her6al 2lants and sought S@uac$ doctorsT and S%anghihilotT *hene)er his son got sic$. The' used their 2ersonal -a%il' -und to sustain his need -or %edical care. RE6IE$ O8 S5STE- Integumentary system 34 Patient has no an' allergic reaction to certain -oods or %edication, he don0t ha)e an' histor' o- itchiness. (e has lesions, a6rasions and scars in his lo*er e?tre%ities. "o hair d'es, curling or strengthening 2re2aration. ,ead, Eyes, Ears, Nose, T%roat Patient doesn0t -elt an' dizziness, lightheadedness and headache. So%eti%es he e?2erienced seizures es2eciall' *hen it is cold and tingling sensation attac$. (e doesn0t use an' e'eglasses. "o hearing 2ro6le% 2atient e?2erienced nasal stu--iness so%eti%es. Ne* Patient clai%ed that he doesn0t ha)e an' nec$ lu%2s and *as not diagnose *ith an' th'roid 2ro6le%. 'reast and .:illae Patient did not e?2erience an' 2ain on his 6reast and a?illae. T%ora: and #ungs Patient e?2erienced 2roducti)e cough *ith thic$ 'ello* s2utu%. "o histor' and d's2nea, asth%a, 2neu%onia, and e%2h'se%a. (e doesn0t -elt an' chest 2ain. Cardio!asular System Patient doesn0t ha)e an' histor' o- cardio)ascular disease. &astrointestinal System Patient e?2erienced a6do%inal cra%2s and h'2eracti)e 6o*el %o)e%ent *ith *ater' stool characterized *ith 'ello*:green in color *hich lasted -or t*o da's. Patient e?2erienced a6do%inal 2ain in the lo*er 2ortion o- the a6do%inal ca)it'E it 7ust lasted -or -e* %inutes and di%inished. (e used to drin$ hot *ater to relie)e the 2ain, he also e?2erienced -latulence -or 3? a da', -or that da' onl'. (e don0t an' ha)e di--icult' in s*allo*ing. -usulos*eletal System Patient clai%ed that he e?2erienced li$e an electric current sensation on his 6oth legs. !t is gradual characterized -irst 6' the *ea$ness o- his legs -ollo*ed 6' the tingling sensation and nu%6ness on his legs es2eciall' in the le-t leg. Because o- this, he had li%ited range o- %otion and he can0t %o)e his 6oth legs. Tingling sensation o-ten attac$ earl' in the %orning and late a-ternoon and a cou2le o- ti%e during hour slee2 as clai%ed 6' the 2atient. (e also had loss o- -unction *ithout 2ain in her legs. Neurologi System 35 Patient e?2erienced tingling sensation, nu%6ness and uncontrolled %o)e%ents acco%2anied *ith tre%ors on his lo*er e?tre%ities. Patient can0t -eel light 2ressure onl' dee2 2ressure and 2ain through 2ointing 2oint o67ect. 7rinary System Patient urinates .:/? a da', he ha)e di--icult' in urination 6ecause he need assistance tot go to co%-ort roo%. But he doesn0t ha)e an' 2ain-ul urination. ,ematologi Patient clai%s that he doesn0t ha)e an' histor' o- ane%ia. Endorine System Patient )er6alizes u2on assess%ent that he cannot tolerate *ar% en)iron%ent since in their 2lace the' ha)e -resh air. (e doesn0t ha)e an' th'roid 2ro6le%s. Psy%iatri Patient can %anage the stress that his ha)ing no*. !n -act, he is a ha22' 2erson. (e has a good %e%or' and 6ut he also tend to get ner)ous easil' *hen strange 2eo2le li$e us tal$ to hi% and he tend to 2ers2ire %ore.
P,5SIC.# .SSESS-ENT 36 &ate o- Assess%entI Se2te%6er .9:.;, .>>; Ti%e o- assess%entI >3I132% ,ital signs u2on assess%entI #eneral Sur)e'I Patient is a*a$e a22eared 2ale and his legs *ere nu%6 and *ea$, 2atient lies on 6ed in a su2ine 2osition. (e a22eared untid' *ith oil' -ace, hair *hich is not 2ro2erl' co%6ed and tangled. Patient is coherent and res2onsi)e during our inter)ie*E he $ee2s in s%iling and -elt sh' to ans*er our @uestions. Ongoing !,8 solution o- &3!MB *ith the dro2 rate o- +3gttsL%in, 2atentl' hoo$ed at the right dorsal %etacar2al )ein.
!ntegu%entar' S'ste%I S$inI Patient has a -air s$in #ood s$in turgor noted Lesion noted in the lo*er e?tre%ities Scar noted at the le-t $nee and le-t -oot &r' s$in noted (airI (air is short, thic$ and reddishL6ro*nish in color, 6rittle hair &oesn0t use hair d'es "o lice in-estation noted &andru-- noted "ailsI Untri%%ed, dirt' nails on 6oth -ingers and toes Blanch ca2illar' re-ill test M/ seconds Patients -ingernails and toenails are thic$ "ails are con)e? *ith an angle at a6out +4> degrees (ead, E'es, Ears, "ose, Throat <(EE"T= Se+tember 2B, 2DDC Se+tember 2C, 2DDC T U /4.5WC T U /4.9WC P U 99 62% P U ;> 62% R U .> c2% R U +; c2% 'PU ++>L5> %%(g 'PU ++>L5> %%(g 37 S$ull and 8aceI "or%oce2halic and s'%%etrical *ith -rontal, 2arietal, and occi2ital 2ro%inence A6sence o- nodules and %asses u2on 2al2ation Can -le? head *ithout su22ort 8acial -eatures and %o)e%ents are s'%%etrical E'es and ,isionI
E'e6ro*s are thin, 6ut s'%%etricall' aligned 8re@uent e'e 6lin$ing "o discharges, no discoloration and no %asses noted Sun$en e'es and e'e 6ags noted Pu2il E@uall' Round Reacted to Light and Acco%%odation Ears and (earing Auricles sa%e color as -acial s$in, s'%%etrical and are aligned *ith outer canthus o- e'e A6le to hear s2o$en *ords clearl' A6le to hear *atch tic$ing in 6oth ears Pinna is %o6ile, -ir% and not tender Pinna recoils a-ter it is -olded Presence o- ceru%en noted "ose and Sinuses E?ternal nose has sa%e color as -acial s$in e?ce2t -or sa%e 2arts *ith s%all 2ig%ents "o discharges noted "o tenderness and %asses noted "o sinusitis noted Oro2har'n? <%outh and throat= Li2s are 2ale and dr' "o s*elling o- the tongue noted "o 2al2a6le nodules Bad 6reath noted "o 6leeding and s*elling o- gu%s noted 38 Pla@ues on teeth noted "o tonsillitis noted #ag Re-le? noted "ec$I Th'roid gland is not )isi6le Patient can turn head le-t and right, u2 and do*n *ithout 2ain "o 2al2a6le nodules Thora? and Lungs "o di--icult' o- 6reathing "o a6nor%alities noted Posterior Thora? "or%al cur)ature "o tenderness u2on 2al2ation S'%%etric Anterior Thora? Chest is s'%%etric "or%al 6reath sounds noted "o e)idenced o- an' secretions Breast and A?illae "o discharges noted S$in uni-or% in color, areola dar$en in color "o e)idence o- enlarge%ent o- li)er and s2leen Audi6le 6o*el sounds Musculos$eletal S'ste% Li%ited %o)e%ents in the lo*er e?tre%ities Bea$ness o- his legs 6oth right and le-t Tingling sensation, uncontrolled %o)e%ents "u%6ness o- the legs 6oth right and le-t 39 Patient didn0t res2onse to light touch Patient res2onse to dee2 2ressure onl' li%ited a6ilit' to 2er-or% grossL-ine %otor s$ills, di--icult' turning his 6od' slo*ed %o)e%ent and uncoordinated %o)e%ent 2ostural insta6ilit', ina6ilit' to %aintain acti)it'. Cardio)ascular S'ste% "o a6nor%alities noted Lu6:du6 sounds noted u2on auscultation "o ede%a Urinar' S'ste% Patient urinate /? a da' Patient0s urine is 'ello*ish in color #astrointestinal S'ste% "o )o%iting "o diarrhea "o di--icult' in s*allo*ing (ard stool noted "eurologic S'ste% Mental StatusI Language Patient does not ha)e an' s2eech 2ro6le%s. (e can understand and con)erse *ell using Bisa'a dialect. (e used non:)er6al co%%unication such as e'e %o)e%ents, gestures and interaction *ith the su22ort 2erson. (e had a congruence o- non:)er6al and )er6al e?2ression. Orientation Patient is oriented to 2lace, ti%e and is a6le to ans*er our @uestions correctl' during inter)ie*. 40 Me%or' (e has good %e%or' and can recall *hat ha22ened in the 2ast. Attention S2an Patient is res2onsi)e and coherent. CR.NI.# NER6E .SSESS-ENT 41 CRA"!AL "ER,E "AME RESULT ! Ol-actor' Patient is a6le to s%ell and he can identi-' i- *hat he s%ells. !! O2tic (e *as a6le to read our na%e2lates a6out +1 inches. (e has 6right e'es and can see clearl'. !!! Occulo%otor Patient0s 2u2il reacted to light. Pu2ils constrict *hen loo$ing at near o67ect and dilate *hen loo$ing -ar o67ect. !t also con)erges *hen 2enlight *as %o)ed to*ards his nose. !, Trochlear Bhen 2enlight *as %o)ed at si? cardinal -ields o- gaze using the si? ocular %o)e%ents na%el'I su2erior rectus, lateral rectus, in-erior rectus, su2erior o6li@ue, %edial rectus and in-erior o6li@ue 2atients 6oth e'es *ere coordinated and %o)ed in unison*ith 2arallel align%ent. , Trige%inal Positi)e 6lin$ re-le? *ith3 6lin$sL%inute and can deter%ine 6lunt and shar2 ends. ,! A6ducens Using the si? ocular %o)e%ents, he *as a6le to %o)e e'e6alls laterall' o- 6oth e'es *ith unison and in 2arallel align%ent. ,!! 8acial Patient -lashed his s%ile *hen as$ed o- so%ething 2ri)ate and 2ersonal. And close his together and a6le to raise e'e6ro*s. ,!!! AcousticLAuditor' Patient can hear clearl' and onl' seldo% @uestions *ill 6e re2eated *hile *e *ere inter)ie*ing hi%. !A #losso2har'ngeal The 2atient *ill 6e a6le to identi-' )arious taste 2laced on ti2 and sides o- tongue. (e *as also a6le to %o)e tongue -ro% side to side and u2 and do*n *hen as$ed to do. Positi)e gag re-le?. 42 43 &lasgo" Coma Sale 8acult' Measured Res2onse Score E'e O2ening S2ontaneous:o2en *ith 6lin$ing at 6aselineXXXXXXXXXX12ts PPPP To )er6al sti%uli, co%%and, s2eechXXXXXXXXXXXXXXXX/2ts To 2ain onl'<not a22lied to -ace=XXXXXXXXXXXXXXXXXXX.2ts "o res2onseXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX+2t ,er6al Res2onse OrientedXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX32ts Con-used con)ersation, 6ut a6le to ans*er @uestionXXXX12ts PPPPP !na22ro2riate *ordsXXXXXXXXXXXXXXXXXXXXXXXXXXXXX/2ts !nco%2rehensi6le s2eechXXXXXXXXXXXXXXXXXXXXXXXXX.2tS "o res2onseXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX+2t
Motor Res2onse O6e's co%%and -or %o)e%entXXXXXXXXXXXXXXXXXXXX42ts Pur2ose-ul %o)e%ent to 2ain-ul sti%ulusXXXXXXXXXXXX32ts PPPP Bithdra* in res2onse to 2ainXXXXXXXXXXXXXXXXXXXXX12ts 8le?ion in res2onse to 2ain<decorticate 2ositioning=XXX/2ts E?tension res2onse to 2ain<dece6erate 2ositioning=XXX.2tS "o res2onseXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX+2t XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX Total Score U +/L+3 44 -7SC#E STREN&T, SC.#E > "o detection o- %uscular contraction + A 6arel' detecta6le -lic$er on trace o- contraction *ith o6ser)ation in 2al2ation. . Acti)e %o)e%ent o- 6od' 2art *ith eli%inate o- gra)it'. / Acti)e %o)e%ent against gra)it' onl' and not against resistance. 1 Acti)e %o)e%ent against gra)it' and so%e resistance. 3 Acti)e %o)e%ent against -ull resistance *ithout e)ident -atigue <nor%al %uscle strength= -7SC#E STREN&T, Le-t Lo*er E?tre%ities Right Lo*er E?tre%ities Plantar -le?ion > > &orsi-le?ion > > nee 8le?ors > > nee E?tensors > > (i2 8le?ors > > (i2 E?tensors > > !n)ersion and e)ersion > > 45 Re-le?I The 2atient0s Bice2s, Trice2s, Brachioradialis, Patellar and Achilles ha)e the -ollo*ing grade o- res2onsesI R., R., R+, >, >, > res2ecti)el'. Scale o- grading Re-le?I >:+> re-le? res2onse R+U %ini%al acti)it' <h'2oacti)e= R.U nor%al res2onse R/U %ore acti)e than nor%al R1U %a?i%al acti)it' <h'2eracti)e= SPatient RT R!#(T LE8T BRAC(!ORA&!AL!S BRAC(!ORA&!AL!S R+ R+ B!CEPS B!CEPS 46 R. R. TR!CEPS TR!CEPS R. R.
"EE RE8LEAL PATELLAR "EE RE8LEAL PATELLAR > > A"LE RE8LEA A"LE RE8LEA > > 47 0OCTOR(S OR0ER >;L.3L>; +>I.3 a% Pls. ad%it 2t. to 2edia %isc. TPR e)er' 1 hour La6sI CBC, "a, Creatinine, uLa Urinal'sis A8B AST Start &3!MB to -e* at +3 Monitor )Ls e)er' 1 hours &r. PatiYo ++I13 a% re-er result *hen in noted ascending 2aral'sis >;L.4L>; TU /5..ZC ,it. B co%2le? Eat + 6anana 8ollo* u2 !,8 &r. PatiYo +>I3> 2% ('drocortisone +>>%g !,TT e)er' 9Z >;L.5L>; TU /5.+ZC Continue %edication >;L.9L>; >;I+3a% Continue %edication +>I.1 2% !,8 to -ollo* &3!MB 3>>%l &r. Mantilla
Contraindiation: Contraindicated in 2atients h'2ersensiti)e to drug or its co%2onents and in those *ith rectal 6leeding, gastroenteritis, intestinal o6struction, a6do%inal 2ain, nausea, )o%iting, or other s'%2to%s o- a22endicitis or acute surgical a6do%en. .d!erse ReationI Mild cra%2ing nausea, diarrhea -luid and electrol'tes distur6ances <es2eciall' 2otassiu% and calciu%=. #!I nausea, )o%iting. A6do%inal cra%2s, diarrhea, 6urning sensation in rectu%, 2rotein:losing entero2ath', la?ati)e de2endence Meta6olicI al$alosis, h'2o$ale%ia Musculos$eletalI %uscle *ea$ness, tetan' 51 Nursing Im+liation: Add high:-i6er -oods slo*l' to regular diet to a)oid gas and diarrhea. Ade@uate -luid inta$e includes at least 4:9glassesLd. &o not 6reast-eed *hile ta$ing this drug *ithout consulting 2h'sician. Bisco:La? %a' contain tartrazine #i)e drug at ti%es that don0t inter-ere *ith scheduled acti)ities or slee2. So-t, -or%ed stools are usuall' 2roduced +3 to 4> %inutes a-ter rectal use. Be-ore gi)ing -or consti2ation, deter%ine *hether 2t. has ade@uate -luid inta$e, e?ercise, inta$e and diet. Ta6lets and su22ositories are used together to clean the colon 6e-ore and a-ter surger' and 6e-ore and a-ter surger' and 6e-ore 6ariu% ene%a. !nsert su22ositor'as high as 2ossi6le into the rectu% , and tr' to 2osition su22ositor' against the rectal *all. A)oid e%6edding *ithin -ecal %aterial 6ecause doing so %a' dela' onset o- action. 52 &eneri name: .sorbi .id 16itamin C2 'rand names: .+o4C, .sorbia+, Cebid, eon, enolate, emin, 4s+an, etane, es!ain Classifiation: ,ita%in .tion: Bater:solu6le )ita%in essential -or s'nthesis and %aintenance o- collagen and intercellular ground su6stance o- the 6od' tissues cell, 6lood )essels, cartilages, 6ones, teeth, s$in, and tendons. Indiation: Pro2h'la?is and treat%ent o- scur)' and as a dietar' su22le%ent. To 2re)ent )it. C de-icienc' in 2t. *L 2oor nutritional ha6its or increased re@uire%ents. R&A 8ran$ and su6clinical scur)' E?tensi)e 6urns, dela'ed -racture or *ound healing, 2osto2erati)e *ound healing, se)ere -e6rile or chronic dse. State. 0osage, Route of administration: < tab O0, PO Contraindiation: Use o- sodiu% ascor6ate in 2atients on sodiu% restrictionE use in calciu% ascor6ate in 2atients recei)ing digitalis. .d!erse Reation: "ausea, )o%iting, heart6urn, diarrhea, or a6do%inal cra%2s, acute he%ol'tic ane%ia, sic$le cell crisis, headache or inso%nia, urethritis, d'suria, cr'stauria, h'2erla?alunia, h'2erurice%ia, %ildness soreness at in7ection site, dizziness, te%2orar' -aintness *ith ra2id !, ad%inistration Nursing im+liationI (igh doses o- )ita%in C are not reco%%ended during 2regnanc'. Ta$e large doses o- )ita%in C in di)ided a%ounts 6ecause the 6od' uses onl' *hat is needed at a 2articular ti%e and e?cretes the rest in urine. Megadoses can inter-ere *ith the a6sor2tion o- )ita%in B+.. "oteI )ita%in C increases the a6sor2tion o- iron *hen ta$en at the sa%e ti%e as iron rich:-oods. &o not 6reast-eed *hile ta$ing this drug *ithout consulting 2h'sician. Stress 2ro2er nutritional ha6its to 2re)ent recurrence o- de-icienc'. Ad)ise s%o$ers to increase inta$e o- )ita%in C. Bhen gi)ing -or urine acidi-ication, chec$ urine 2( to ensure e--icac'. 8or 2t. recei)ing )it. C !.M., e?2lain that M.!, route %a' 2ro%ote 6etter utilization. 53 &eneri name: ,ydroortisone 'rand nameI Corte-, cortene%a, h'drocortone ClassifiationI S$in and Mucous Men6rane AgentE Anti:!n-la%%ator'E s'nthetic (or%oneE adrenal corticosteroidsE glucocorticoidE %ineralocorticoid .tionI Short:acting s'nthetic steroid *ith 6oth glucocorticoid and %ineralocorticoid 2ro2erties that a--ect nearl' all s'ste% o- the 6od'. ('drocortisone has anti:in-la%%ator', i%%unosu22ressi)e, %etha6olic -unction in the 6od'.
IndiationI Re2lace%ent thera2' in adrenocortical insu--icienc'E to reduce seru% calciu% inh'2ercalce%ia, to su22ress undesira6le in-la%%ator' or i%%une res2onses, to 2roduce te%2orar' re%ission in nonadrenal disease, and to 6loc$ ACT( 2roduction in diagnostic tests. Use as anti:in-la%%ator' or i%%unosu22ressi)e agent largel' re2laced 6' s'nthetic glucocorticoids that ha)e %ini%al %ineralocortocoid acti)it'. 0osage, Route of administration: +>> gra%s !,TT e)er' 9 hours ContraindiationI ('2ersensiti)it' to glucocorticoids, idio2athic thro%6oc'to2enic 2ur2ra, 2s'choses, acute glo%erulone2hritis, )iral or 6acterial diseases o- s$in. .d!erse Reation: eu2horia, inso%nia, 2s'chotic 6eha)ior, 2seudotu%or cere6ri, seizures, heart -ailure, h'2ertension, ede%a. Arr'th%ias, thro%6oe%6olis%, cataracts, glauco%a, 2e2tic ulceration, gastrointestinal irritation, increase a22etite, 2ancreatitis, h'2o$ale%ia, h'2ergl'ce%ia, car6oh'drate intolerance, %uscle *ea$ness, gro*th su22ression in children, osteo2orosis, hirsutis%, dela'ed *ound healing, acne, )arious s$in eru2tion, eas' 6ruising. Nursing Im+liationI Teach 2atient signs o- earl' adrenal insu--icienc' Barn 2atient a6out eas' 6ruising Ad)ise hi% to consider e?ercise or 2h'sical thera2' Barn 2atient recei)ing long:ter% thera2' a6out cushingoid s'%2to% &eter%ine *hether the 2t is sensiti)e to other corticosteroid. #i)e oral dose *ith -ood *hen 2ossi6le.2t. %a' need another drug to 2re)ent #! irritation. Most ad)erse reaction to corticosteroids are dose:duration:de2endent. Monitor 2t. *eight BP, and electrol'te le)el Monitor 2t. cushingoid e--ects including %oon -ace, 6u--alo hu%2, central o6esit', thinning hair, h'2ertension and increased susce2ti6ilit' to in-ection. 54 &ENERIC N.-E: 6IT.-IN ' CO-P#E9 4 OR.# 'R.N0 N.-E1S2: Surbe:, T%era!ite, 6ion4C, E4'e 7SES: ,ita%ins are the 6uilding 6loc$s o- the 6od'. The' are used to 2re)ent or treat a )ita%in de-icienc' due to 2oor nutrition, certain illnesses or during 2regnanc'. ,O$ TO 7SE: Ta$e as directed. 8ood %a' a--ect the a6sor2tion o- certain )ita%in 2roducts. Consult 'our 2har%acist. Che*a6le ta6lets %ust 6e che*ed thoroughl' 6e-ore s*allo*ing -ollo*ed *ith a glass o- *ater. Ti%ed:release ca2sules or ta6lets %ust 6e s*allo*ed *hole. SI0E E88ECTS: This %edication %a' cause %ild nausea or un2leasant taste. Consult 'our doctor i- an' o- these e--ects 2ersist or 6eco%e se)ere. !- 'ou notice other e--ects not listed a6o)e, contact 'our doctor or 2har%acist. PREC.7TIONS: Be-ore using this %edication, tell 'our doctor or 2har%acist 'our %edical histor', es2eciall' o-I dia6etes, 6lood disorders such as )ita%in B+. de-icienc' <2ernicious ane%ia=. Tell 'our doctor i- 'ou are 2regnant 6e-ore using this %edication. "o 2ro6le%s ha)e 6een re2orted in 2regnant or nursing *o%en *hen this %edication *as used in nor%al doses. 0R7& INTER.CTIONS: Tell 'our doctor i- 'ou ta$e an' other %edication, including non2rescri2tion. This %edication %a' a--ect certain urine la6 tests, including so%e urine glucose tests. &o not start or sto2 an' %edicine *ithout doctor or 2har%acist a22ro)al. O6ER0OSE: !- o)erdose is sus2ected, contact 'our local 2oison control center or e%ergenc' roo% i%%ediatel'. US residents can call the US national 2oison hotline at +: 9>>:...:+.... Canadian residents should call their local 2oison control center directl'. S'%2to%s o- o)erdose %a' include diarrhea, loss o- coordinationE nu%6ness o- the hands or -eetE 7oint 2ain, or 2ain-ul urination. 55 56 Predis2osing -actorI P.T,OP,5SIO#O&5 Preci2itating -actorI <&iagra%= Infectious organism: invasion of Campylobacter jejuni via oral route To cause gastrointestinal infection (iarr!ea " a#ominal cram$ing% C. jejuni unergoes significant $!&siologic c!anges '(in t!e intracellular environment to avoi mi)ture to l&sosomal en*&mes '(c coul eat " +ill t!em Immune s&stem 'ill res$onse to t!e intracellular invasion of microorganism MOLECULAR MIMICRY DUAL RECOGNITION umoral immunity Cell!me"iate" immunity ,ener: -ale (-ale to female ratio is 1:5:1% .ge: 16 &ears ol (/oung aults age 15035 &0o% (1lerl& age 50075 &0o% 2I1T: 13 eating uncoo+e foo (es$3 $oultr& $roucts% 23 45inila'6 33 7a' eggs 2I.7781. 57 2ecrease m&elin $rouction DEMYELINATION Impaire" tran#mi##ion o$ ner%e con"uction Tingling sensation 9um#ness :ea+ness of t!e ;1 &en#ory an" motor lo## <onsti$ation Ina#ilit& to $erform .2; Immo#ilit& of t!e ;1 .scening $aral&sis GUILLAIN 'ARRE &YNDROME Lymp(o)ine# $rouce macro$!ages activation -ista+en immune attac+ ma& arise Inflammation of t!e nerve cells =enetration of macro$!age an anti#oies into #asement mem#rane aroun nerve fi#ers T0cells release l&m$!o+ines Increase level of l&m$!oc&tes level .ctivates s$ecific T l&m$!oc&tes or T0cells Antibo"ie# 'ill fig!t foreign microorganisms Inflame cells secrete c&toto)ic su#stances t!at affect or amage t!e &c(*ann cell# >ecrete anti#oies 58 N7RSIN& C.RE P#.N F< Se2te%6er .9, .>>; Su67ecti)e cuesI SPas%o ra %an da* ni sa $usog $a' %anhi%asa %an $o hu%an 6a$tasT as )er6alized 6' the 2atient. O67ecti)e cuesI )Ls ta$en as -ollo*I Te%2I /4.3 c RRI +9c2% PRI 9462% BPI++>L5>%%(g A2ath' noted Misinter2retation o- in-or%ation &iagnosisI Kno"ledge defiit related to ogniti!e limitation PlanningI A-ter 1 hours o- rendering nursing inter)ention 2atient *ill 6e a6le to )er6alize understanding o- condition disease 2rocess and treat%ent Inter!ention: Rationale +. &eter%ined in-or%ation the client alread' $no*s and %o)e to *hat the client does not $no*, 2rogressing -ro% si%2le to co%2le? To -acilitate learning and deter%ine the client and SO0s cogniti)e li%itation .. E?2lained the cause o- the s'%2to%s and disease To 2ro)ide $no*ledge /. E?2lained the goal o- treat%ent To 2ro)ide a22ro2riate in-or%ation 1. Pro)ide an en)iron%ent that is conduci)e to learning To -acilitate learning 3. !denti-' su22ort 2ersons or SO re@uiring in-or%ation To let the SO a*are o- the condition o- the client E)aluationI #oal %et. A-ter 1 hours o- rendering o- nursing inter)ention the 2atient *as a6le to 2artici2ate in learning 2rocess and *as a6le to )er6alize understanding o- condition o- treat%ent. 59 N7RSIN& C.RE P#.N F2 Se2te%6er .9, .>>; Su67ecti)e CueI S&ili $o $ala$a* %a0a% $a' *ala ga7ud $usog a$o tiilT. As )er6alized 6' the 2atient O67ecti)e cuesI Li%ited range o- %otion, li%ited a6ilit' to 2er-or% grossL-ine %otor s$ills, di--icult' turning, slo*ed %o)e%ent uncoordinated %o)e%ent, %o)e%ent induced, 2ostural insta6ilit', ina6ilit' to %aintain acti)it'. ,LS ta$en as -ollo*I Te%2I /4.3 WC RRI +9 c2% PRI 94 62% BP I ++>L5> %%(g "ursing &iagnosisI !%2aired 2h'sical %o6ilit' related to ina6ilit' to %aintain acti)it' as e)idenced 6' li%ited range o- %otion. PlanningI Bithin 9 hours o- gi)ing a22ro2riate nursing inter)ention, 2atient *ill 6e a6le to 2artici2ate in Acti)ities o- &ail' Li)ing and desired acti)ities. !nter)entionsI +. Monitor )ital signs Baseline data during %edication o- 2rocedures. .. O6ser)e %o)e%ent *hen client is una*are o- o6ser)ation. To note an' incongruence *ith re2orts o- a6ilities. /. "ote e%otionalL 6eha)ioral res2onses to 2ro6le%s o- i%%o6ilit'. 8eelings o- -rustrationL2o*erless %a' i%2ulse attain%ent o- goals. 1. Encourage 2artici2ation in sel- care, di)ersional acti)ities. Enhances sel- conce2t and sense o- inde2endence. 3. !denti-' energ': conser)ing techni@ues -or A&L0s. Li%its -atigue, %a?i%izing 2artici2ation. 4. Encourage ade@uate inta$e o- -luidsL nutritious -oods Pro%otes *ell 6eing and %a?i%izes energ' 2roduction. 5. Encourage clientsLSO0s in)ol)e%ent in decision %a$ing as %uch as 2ossi6le. Pro%otes *ell 6eing and %a?i%izes energ' 2roduction. E)aluationI #oal *as not %et. Patient *as not a6le to 2artici2ate in Acti)ities o- &ail' li)ings and desired acti)ities. ?< 60 N7RSIN& C.RE P#.N F= Se2te%6er .9, .>>; Su67ecti)e cueI SBa'a 2a a$o $aligo 2ila na $aadla*T as )er6alized 6' the 2atient. O67ecti)e cuesI )Ls ta$en as -ollo*I Te%2I /4.3 c RRI +9c2% PRI 9462% BPI++>L5>%%(g &irt' nails noted Bad 6od' odor noted &andru-- noted (alitosis noted Patient is not 2ro2erl' groo%ed &r' s$in noted &iagnosisI Self4are defiit related to im+aired +%ysial mobility PlanningI A-ter . hours o- rendering nursing inter)ention 2atient *ill 6e a6le to 2er-or% sel-: care acti)ities *ithin 2h'sical li%itations. Inter!ention: Rationale +. &eter%ined indi)idual strengths and s$ills Lo- the client To $no* the strengths and *ea$nesses o- the client as 6asis in gi)ing a22ro2riate inter)entions .. Pro)ide -or co%%unication a%ong those *ho are in)ol)ed in caring To gain trust and coo2eration -ro% the client and SO /. Pro)ide health teaching to 2atient a6out the i%2ortance o- good h'giene To 2ro%ote good h'giene to the 2atient 1. &e)elo2 2lan o- care a22ro2riate to indi)idual situation, scheduling acti)ities to con-or% to clients nor%al schedule To encourage 2er-or%ance o- A&L *ithin 2h'sical li%itation 3. Plan ti%e -or listening to the client and SO To disco)er 6arriers to 2artici2ation in regi%en 63 &e%onstrated to the client and SO the 6asic *a's in sel- care such as hand *ashing, co%6ing the hair, tri%%ing nails, tooth 6rushing and 6athing To 2ro)ide a*areness that sel- care acti)ities are still 2ossi6le e)en *ith 2h'sical li%itations 61 5. Encouraged 2atient and SO to use 2roducts to enhance sel- i%age such as deodorant To 2ro%ote sel- care E)aluationI #oal %et. A-ter 1 hours o- rendering nursing inter)ention 2atient *as a6le to 2er-or% sel-:care acti)ities such as co%6ing, tooth 6rushing and tri%%ing o- nails. 62 N7RSIN& C.RE P#.N F> Se2te%6er .9, .>>; Su67ecti)e cuesI S "anhina %an a$o %aa%, %urag na*al an $o ug $usogT , as )er6alized 6' the 2atient. O67ecti)e CuesI )Ls ta$en as -ollo*I Te%2I /4.3 c RRI +9c2% PRI 9462% BPI++>L5>%%(g &ecreased 2h'sical strength &ecreased %o6ilit' Bea$ness "ursing &iagnosisI Po*erlessness related to decreased 2h'sical strength. PlanningI A-ter 9 hours o- rendering nursing care the 2atient *ill 6e a6le to e?2ress sense o- control o)er the 2resent situation and ho2e-ulness a6out -uture outco%es. !nter)entionsI +. Encourage client to 6e acti)e in o*n health care %anage%ent and to ta$e res2onsi6ilit' -or choosing o*n actions and reactions. Can enhance -eelings o- 2o*er and sense o- 2ositi)e sel- \estee%. .. E?2ress ho2e -or client and encourage re)ie* o- 2ast e?2eriences *ith success-ul strategies. Sho* concerns to client as a 2erson. /. Acce2t e?2ressions o- -eelings, including anger and reluctance, to tr' to *or$ things out. Being a6le to e?2ress -eelings -reel' ena6les client to sort out *hat is ha22ening and co%e to a 2ositi)e conclusion. 1. Ma$e ti%e to listen to client0s 2erce2tions o- the situation. Sho*s concern -or client as a 2erson. 3. Listen to state%ents client %a$es *hich %ight indicate -eelings o- 2o*erlessness. Suggest concerns regarding on 2o*erL a6ilit' to control situation. 4. Monitor )ital signs. To ha)e 6aseline data. E)aluationI 63 #oal %et. Patient *as a6le to e?2ress sense o- control and ho2e-ulness a6out -uture outco%es. N7RSIN& C.RE P#.N F? Se2te%6er .9, .>>; Su67ecti)e cueI S"a6iro $o nga di na $o %a$ala$a*T as )er6alized 6' the 2atient O67ecti)e cueI )Ls ta$en as -ollo*I Te%2I /4.3 c RRI +9c2% PRI 9462% BPI++>L5>%%(g Poor e'e contact Tear-ulness during con)ersation ,er6alization o- concerns (refer to subjective cue) Anal'sisI .n:iety related to t%reat on role funtion seondary to +%ysial illness PlanningI A-ter 9 hours o- dut' 2atient *ill 6e a6le to identi-' health' *a's to deal *ith and relie)e an?iet' !nter)ention Rationale +. Pro)ided o22ortunities -or @uestion and ans*er session Enhance sense o- trust and nurse client relationshi2 .. Co%2ared )er6al and non:)er6al res2onses /. Encouraged )er6alization o- -eelings To note %is2erce2tion o- situations To 2ro)ide a22ro2riate e%otional su22orti)e care 1. &iscussed the disease o- #uillain: Barre S'ndro%e 3. Enu%erated *a's the 2atient %a' use to relie)e an?iet' such as acce2ting the realit' o- his condition, o2ti%istic *a' o- seeing things and ha)ing -aith in #od0s lo)e To 2ro)ide in-or%ation that could hel2 2atient understand conditions To 2ro)ide in-or%ation and to 6oost 2atient0s ho2e E)aluationI 64 #oal 2artiall' %et. A-ter 9 hours o- inter)ening, the 2atient *as a6le to enu%erate *a's to relie)e an?iet' 6ut )er6all' said, S Bisan na$asa6ot na $o..&ili ga7ud na$u %ali$a'an na %ag:isi2 ng a$o $ahi%tang $aron.T N7RSIN& C.RE P#.N F@ Se2te%6er .9, .>>; Su67ecti)e cuesI ] Mahadlo$ lage a$o %otindog $a' 6asin %atu%6a a$oT as )er6alized 6' the 2atient. O67ecti)e cuesI )Ls ta$en as -ollo*I Te%2I /4.3 c RRI +9c2% PRI 9462% BPI++>L5>%%(g &i%inished 2roducti)it' A)oidance 6eha)ior !ncreased 2ers2iration Pallor &iagnosisI 8ear related to loss o- 2h'sical su22ort as e)idenced 6' di%inished 2roducti)it'. PlanningI A-ter t*o da's o- rendering a22ro2riate nursing care 2atient *ill dis2la' a22ro2riate range o- -eelings lessened -ear. !nter)entionsI + .Co%2are )er6alL non:)er6al res2onses. To note congruencies as o- situation. .. Sta' *ith the client or %a$e arrange%ents to ha)e so%eone else 6e there. Sense o- a6andon%ent can e?acer6ate -ear. /. Pro)ide in-or%ation in )er6al and *ritten -or%. S2ea$ in si%2le sentences and concrete ter%s. 8acilitate understanding and retention o- in-or%ation. 1. Pro)ide o22ortunit' -or @uestions and ans*er honestl'. Enhances sense o- trust to nurse:client relationshi2 3.Present o67ecti)es in-or%ation *hen a)aila6le an d allo* client to use it -reel'. A)oid arguing a6out client 2erce2tions o- the situations. Li%its con-licts *hen -ear res2onse %a' i%2air rational thin$ing. 4.Pro%ote client control *here 2ossi6le and health client identi-' and acce2t those things o)er *hich control is not 2ossi6le. strengthen internal locus o- control 5.E?2lain 2rocedures *ithin le)el o- clients a6ilit' to understand and handle. To 2re)ent con-usion or o)erload 9.Encourage assist client to de)elo2 e?ercise 2rogra%. 65 Pro)ides a health' outlet -or energ' generated 6' -ear-ul -eelings and 2ro%otes rela?ation. E)aluationI #oal is %et. A-ter . da's o- rendering a22ro2riate nursing care, 2atient is a6le to dis2la' a22ro2riate range o- -eelings and lessened -ear. N7RSIN& C.RE P#.N FA Se2te%6er .;, .>>; Su67ecti)e cueI SMa0a% dili na%an $o $ali6ang ta2os tag duga'T as )er6alized 6' he 2atient. O67ecti)e cueI irrita6le, restlessness, *ea$ness, una6le to %o)e, hard stool. )Ls ta$en as -ollo*I Te%2I /4.3 c RRI +9c2% PRI 9462% BPI++>L5>%%(g "ursing &iagnosisI Altered Bo*el Mo)e%entI Consti2ation related to !nsu--icient Ph'sical Acti)it'. PlanningI A-ter 9 hours o- dut', 2atient *ill 6e a6le to )er6alize understanding o- the i%2ortance o- %o6ilit' and diet to nor%al 6o*el %o)e%ent !nter)entionsI INTER6ENTIONS R.TION.#E !nde2endentI +. Ad)ised 2atient to drin$ ade@uate -luid and include -oods that are high in -i6er li$e 2a2a'a, oat%eal and 2inea22le :to 2ro%ote %oist and so-t stool .. Encouraged acti)it'Le?ercises *ithin 2ersonal li%itation. :to sti%ulate a6do%inal %uscle contraction. /.Pro)ided *ith 2ri)ac' and routinel' scheduled ti%e de-ecation :to 2ro%ote de-ecation 1.Educated 2atient a6out the i%2ortance o- %o6ilit' and diet to nor%al 6o*el %o)e%ent 3."ote energ'. Acti)it' le)el and e?ercise 2attern. 4. Auscultate a6do%en -or the characteristics o- 6o*el sounds :to 2ro)ide in-or%ation : sedi%entar' li-est'le %a' a--ect eli%ination 2atterns : re-lecting 6o*el acti)it' &e2endentI +.Ad%inistered Bisacod'l <2edia= su22ositor' as 2rescri6ed To increase 2eristalsis 2ro%oting eas' de-ecation 66 E)aluationI #oal %et. A-ter 9 hours o- dut', 2atient a6le to de-ecate and )er6alized S na$ali6ang na ga7ud $o %aa%,i%2ortante dia' ga7ud ang e?ercise ug diet la6a* na adtong ta%6al na tagsu$su$ sa a$o lu6ot.T N7RSIN& C.RE P#.N FB Se2te%6er .;, .>>; Su67ecti)eI S&ili $o $ara7a* %a$atulogT as )er6alized 6' the 2atient. O67ecti)esI )Ls ta$en as -ollo*I Te%2I /4.3 c RRI +9c2% PRI 9462% BPI++>L5>%%(g E'e6ags noted 8re@uent 'a*ning noted Restlessness noted Sun$en e'es noted 8atigue An?iet' &ecreased a6ilit' to -unction "ursing &iagnosisI Slee2 Pattern &istur6ance related to en)iron%ental -actors such as e?ternal noise and lac$ o- slee2 2ri)ac'. PlanningI A-ter 9 hours o- dut', 2atient *ill 6e a6le to re2ort i%2ro)e%ent in slee2 2attern. INTER6ENTIONS R.TION.#E !nde2endent +. Pro)ided *ith @uiet and cal% en)iron%ent during 6edti%e To 2ro%ote rest and slee2 .. Ad)ised to li%it -luid inta$e in e)ening :to reduce need -or nightti%e %icturation /. Encouraged 2artici2ation in regular e?ercise 2rogra% during da' :to aid stress controlLrelease o- energ' 1. !denti-ied the -actors that a--ect the slee2ing 2attern :to reduce slee2 distur6ance 3..Reco%%ended to li%it inta$e o- chocolates and ca--einated 6e)erages Such 6e)erages are sti%ulants that inhi6its slee2 &e2endent 67 +. Ad%inistered sedati)e L other slee2 %edication *hen indicated :to enhance clients a6ilit' to -all aslee2 E)aluationI #oal %et. A-ter 9 hours o- dut', 2atient a6le to slee2 co%-orta6l' and re2ort i%2ro)e%ent o- slee2 2attern. N7RSIN& C.RE P#.N FC Se2te%6er .;, .>>; Su67ecti)e cueI SMaula* na$o sa a$o $ahi%tang $aron,T as )er6alized 6' the 2atient. O67ecti)e cueI )Ls ta$en as -ollo*I Te%2I /4.3 c RRI +9c2% PRI 9462% BPI++>L5>%%(g Loss o- 6od' -unction noted Restlessness noted (iding 6od' 2arts *ith 6lan$et <lo*er e?tre%ities= Less e'e contact Bea$ness and nu%6ness <lo*er e?tre%ities= Anal'sisI 0isturbed body image related to +%ysial illness as e!idened by inability to "al* PlanningI A-ter 9 hours gi)ing a22ro2riate nursing inter)ention, 2atient *ill ac$no*ledge sel- as an indi)idual *ho has res2onsi6ilit' -or sel-. Inter!ention Rationale +.Encouraged -a%il' %e%6er to treat client nor%all' and not as in)alid. To a)oid -eeling o- isolation or re7ection ..Encouraged e?2ression o- -eeling regarding his condition. To 2ro)ide a22ro2riate e%otional su22ort /.Encouraged client to loo$ and touch a--ected 6od' 2arts. To 6egin to incor2orate changes into 6od' i%age 1.&iscussed %eaning o- loss change to client. A change o- -unction such as i%%o6ilit' %a' 6e %ore di--erent -or so%e to deal *ith than a change in a22earance 3.,isited client -re@uentl' and ac$no*ledged the indi)idual as so%eone *ho is *orth*hile Pro)ides o22ortunities -or listening o- 2atient0s concerns and @uestions. 68 E)aluationI #oal %et. A-ter 9 hours gi)ing a22ro2riate nursing inter)ention, 2atient )er6alized -eeling o- acce2tance and res2onsi6ilit' o- his a--ected 6od' 2arts as e)idenced 6' -re@uent chec$ing and touching o- his lo*er e?tre%ities. N7RSIN& C.RE P#.N F<D Se2te%6er .;, .>>; Su67ecti)e cueI STaglaa' na %an $o diri sa hos2italT, as )er6alized 6' the client. O67ecti)e cuesI )Ls ta$en as -ollo*I Te%2I /4.3 c RRI +9c2% PRI 9462% BPI++>L5>%%(g Restlessness noted 8re@uent 'a*ning noted ,er6al e?2ression o- 6oredo% ee2 on l'ing in 6ed "ursing &iagnosisI 0efiient di!ersional ati!ity related to +%ysial limitations and la* of soures. PlanningI A-ter 9 hours o- gi)ing a22ro2riate nursing inter)ention, 2atient *ill 6e a6le to engage in satis-'ing acti)ities *ithin 2ersonal li%itations. Inter!ention: Rationale +.Ac$no*ledged realit' o- situation and -eelings o- the client. To esta6lish thera2eutic relationshi2 ..Pro)ided *ith di)ersional acti)ities such as reading %aterials and tal$ing to the client. To re-ocus the attention o- the client . To relie)e 6oredo%. /.Pro)ided change o- scener' . To direct attention. 1.Encouraged e?2ression o- -eelings To deter%ine concerns that needs inter)ention. 3.Pro)ided re@uire%ents -or %o6ilit' such as *heelchair. 8or %o6ilit'. 4.&e)elo2ed 2lan o- care a22ro2riate to indi)idual situation, scheduling acti)ities to con-or% to clients nor%al To encourage 2er-or%ance o- A&L *ithin 2h'sical li%itation. 69 schedule. E)aluationI #oal %et. A-ter 9 hours o- gi)ing a22ro2riate nursing inter)ention, 2atient )er6alized -eelings o- satis-action in acti)ities engaged *ith in 2ersonal li%itations. N7RSIN& C.RE P#.N F<< Se2te%6er .;, .>>; Su67ecti)e CuesI Sadaghan sad diri ta*o, gusto na a$o ra isa,T as )er6alized 6' the 2atient. O67ecti)e CuesI )Ls ta$en as -ollo*I Te%2I /4.3 c RRI +9c2% PRI 9462% BPI++>L5>%%(g 8atigue O6ser)ed disco%-ort O6ser)ed use o- unsuccess-ul social in reactions 6eha)ior !nsecurit' in 2u6lic &'s-unctional interaction *ith others &iagnosisI !%2aired social interactions related to li%ited 2h'sical %o6ilit'. PlanningI A-ter 9 hours o- gi)ing a22ro2riate nursing inter)ention 2atient *ill e?2ress desireL6e in)ol)ed in achie)ing 2ositi)e changes in social 6eha)iors and inter2ersonal relationshi2s. !nter)entionsI +. !nter)ie* -a%il', SO, and -riends. To o6tain o6ser)ation o- clients 6eha)ior changes. .. &eter%ine client use o- co2ing s$ills and de-ense %echanis%. A--ects a6ilit' to 6e in)ol)ed in social situation /. (a)e client list 6eha)iors that cause disco%-ort. Once recognized, client can choose to change. 1. Bor$ *ith the client to alle)iate underl'ing negati)e sel- conce2ts Because the' a-ter i%2ede social interactions 3. Encourage client to )er6alized 2ro6le%s and 2erce2tions o- reasons -or 2ro6le%s 70 Acti)e listen to note indications o- ho2elessness, 2o*erlessness, -ear, an?iet', grie-, anger, -eeling unlo)ed or unlo)a6leE 2ro6le%s *ith se?ual identit'. E)aluationI #oal %et. A-ter 9 hours o- gi)ing a22ro2riate nursing inter)ention, 2atient e?2ress desireL6e in)ol)ed in achie)ing 2ositi)e changes in social 6eha)iors and inter2ersonal relationshi2s. N7RSIN& C.RE P#.N F<2 Potential "ursing Care Plan Subjective cue: Objective cues: Ascending 2aral'sis noted <-ro% -eet to the 2el)ic 2art= Li%ited ROM Slo*ed 6od' %o)e%ents noted Bea$ness "ursing &iagnosisI ,ig% ris* for im+aired s*in integrity related to immobility as e!idened by asending +aralysis PlanningI A-ter 9 hours o- rendering a22ro2riate nursing inter)entions, 2atient *ill 6e -ree -ro% an' ris$ o- i%2aired s$in integrit'. INTER6ENTIONS R.TION.#E +. Changed 2atient 2osition e)er' . hours. :to 2ro%ote circulation and 2re)ent 6ed sore and consti2ation .. Re%o)ed *etL*rin$led linens 2ro%2tl'. :%oisture 2otentiates s$in 6rea$do*n /. &e)elo2ed re2ositioning schedule -or client, in)ol)ing client in reasons -or and decisions a6out ti%es and 2ositions in con7unction *L other acti)ities. :to enhance understanding and coo2eration. 1. Pro)ided *L *ell )entilated :To 2ro%ote co%-ort 71 en)iron%ent. 3. Ele)ated 6oth legs *ith a 2illo* To 2ro%ote 6lood )enous return 4. Encouraged 2atient to touch his lo*er e?tre%ities e)er' no* and then :To re%ind the 2atient that his lo*er e?tre%ities are 2resent and still needs care 5. !ncreased -luid and high -i6er in diet. :to 2re)ent consti2ation. E)aluationI N7RSIN& C.RE P#.N F<= Potential "ursing Care Plan Su67ecti)e cueI O67ecti)e cuesI Ph'sical i%%o6ilit' Motor d's-unction Bea$ness and nu%6ness <lo*er e?tre%ities= "ursing &iagnosisI Ris$ -or !n7ur' related to Ph'sical !%%o6ilit'. PlanningI Patient *ill 6e a6le to understand o- indi)idual -actors that contri6ute to 2ossi6ilit' o- in7ur'. "ursing !nter)entionI +. Per-or% thorough assess%ent regarding sa-et' issues *hen 2lanning -or client care andLor 2re2aring -or discharge -ro% care. 8ailure to accuratel' assess and inter)ene or re-er these issues can 2lace the client at needless ris$ and creates negligence issues -or the health care 2ractitioner. .. Ascertain $no*ledge o- sa-et' needsLin7ur' 2re)ention and %oti)ation. To 2re)ent in7ur' in ho%e and co%%unit'. /. "ote clients0 de)elo2%ental stage, decision: %a$ing a6ilit', le)el o- cognitionLco%2etence. A--ects clients a6ilit' to 2rotect sel- and in-luence choice o- inter)ention. 1. Assess %ood, co2ing a6ilities, 2ersonalit' st'les. 72 That %a' result in carelessnessLincreased ris$:ta$ing *ithout consideration o- conse@uences. 3. Assess clients0 %uscle strength, gross and -ine %otor coordination. To identi-' ris$ -or -alls. 4. !denti-' inter)entionsLsa-et' de)ices. To 2ro%ote sa-e 2h'sical en)iron%ent and indi)idual sa-et'. 5. &iscuss i%2ortance o- sel- %onitoring o- conditionLe%otions. That can contri6ute to occurrence o- in7ur'. E)aluationI 0ISC,.R&E P#.N "a%eI Patient R 8inal &iagnosisI #uillain Barre0 S'ndro%e Condition u2on &ischargeI !%2ro)ed &ate o- &ischargeI Octo6er >4, .>>; MedicationsI !nstructed 2atient and SO to ta$e the %edication on ti%e. Co%2leted duration o- those o- %edications ta$e ho%e. !nstructed SO to gi)e 2atient *ith Multi)ita%ins. En)iron%ental ConcernsI !nstructed SO to 2ro)ide clean en)iron%ent to 2re)ent lodging o- in-ectious %icroorganis%s. !nstructed SO to 2ro)ide 2ro2er dis2osal o- *astes. !nstructed SO to re%o)e or lessen an' en)iron%ental hazards. Changes in 'our ho%e en)iron%ent can aid in 'our reco)er' 6' %a$ing it easier -or 'ou to 6athe, dress and 2re2are %eals *hile 'our %uscles return to nor%al le)els o- strength. Treat%entsI Encouraged 2atient doing light e?ercise such as *al$ing. Encouraged 2atient to ha)e an ade@uate rest 2eriods. Encouraged SO to 2ro)ide co%-ort %easures to the 2atients. 73 !nstructed SO to change the 2osition o- the 2atient *hen l'ing in 6ed -or long 2eriods o- ti%e to 2re)ent 6ed sores. 8ind a good 2h'sical thera2' 2rogra% -ro% *hich 'ou can learn s2eci-ic iso%etric, isotonic and resistance e?ercises to re6uild *ea$ened %uscles. Jou %a' do these e?ercises on an out2atient 6asis and continue the% at ho%e. Re%e%6er to 2ace 'oursel- and get ade@uate rest, as -atigue is to 6e e?2ected *ith #uillain:Barre S'ndro%e. (ealth TeachingsI Pro)ided 2atient health teaching a6outI 0 Pro2er hand *ashing 0 Pro2er 2ersonal h'giene 0 Tell 2atient to -re@uentl' change 2ositions *hen l'ing in 6ed -or long 2eriods o- ti%e to 2re)ent 6ed sores. Tell 2atient0s %other a6out %onitoring signs ^ s'%2to%s or recurring #uillain: Barre S'ndro%e, eg. Tingling sensation, di--icult' o- s*allo*ing, restlessness, -e)er. !nstructed 2atient to a)oid so%e hea)' *or$s. !nstructed SO to *ell coo$ the -ood. Bear co%-orta6le shoes and soc$s to hel2 soothe 2ain and 6urning -ro% neuro2ath' in the -eet. !ns2ect 'our -eet o-ten to 6e sure there are no cuts or 6listers that 'ou %a' not ha)e noticed. Out Patient <-ollo* u2 chec$:u2=I Encouraged 2atient to ha)e -ollo* u2 chec$:u2 a-ter / *ee$s. !nstructed 2atient to noti-' 2h'sician i- there is an' undesired -eeling a6out the disease. &iet Encouraged 2atient to eat nutritious -ood li$e )egeta6les. Encourage 2atient to eat -ruits rich in )ita%in C -or strong i%%unit'. Ad)ised 2atient to ta$e lo*:sodiu% diet. !nstructed 2atient to a)oid 7un$ -oods. 8ollo* a health' eating 2lan *ith -resh, seasonal -ruits and )egeta6les, lean %eat and -ish, *hole grains and 2lent' o- color-ul salads. Eating *ell %a' hel2 'ou to sustain 'our energ' and can 6oost 'our %ood. S2iritual 74 Encouraged 2atient to attend %ass as -re@uent as he can, or e)en once a *ee$ together *ith his -a%il'. Encouraged 2atient to al*a's 2ra' to #od to hel2 hi% to reco)er i%%ediatel'. Encouraged 2atient than$ #od -or the gi-t o- li-e. Encouraged SO to 2ra' -or the health o- the 2atient. E%otional See$ e%otional su22ort to co2e *ith -eelings o- de2ression and an?iet' that are 2art o- li)ing *ith #uillain:Barre S'ndro%e. &iscuss antide2ressant %edication *ith 'our doctor i- 'ou are ha)ing trou6le *ith acti)ities necessar' -or dail' li)ing. 75 S7--.R5 O8 INTR.6ENO7S 8#7I0S &ateLTi%e Started !ntra)enous 8luids and ,olu%e &ro2 Rate "u%6er o- hours to 6e !n-used >;L.3L>; >;L.4L>; &3!MB +L &3!MB +L +3gttsL%in. +3gttsL%in. +4 hours and /> %inutes +4 hours and /> %inutes >;L.5L>; &3!MB 3>>%l +3gttsL%in. 9 hours and +3 %inutes +>L>+L>; &3LR +L +3gttsL%in +4 hours and /> %inutes +>L>.L>; &3LR +L +3gttsL%in +4 hours and /> %inutes +>L>/L>; &3LR +L +3gttsL%in +4 hours and /> %inutes +>L>1L>; &3LR +L +3gttsL%in +4 hours and /> %inutes +>L>3L>; &3LR +L +3gttsL%in +4 hours and /> %inutes 76 '. &ENO&R.- LegendI 4; 'ear old 43 'ear old Mother died at the age o- 5+ 'ear +;;9 died at the age o- 49 'ear .>>3 8ather #rand-ather 34 'ears old 1/ 'ears old #rand%other Si6lings Patient #BS Cough Arthritis #eneralized S*elling &eceased 77 0efinition of Terms .utoimmune: Pertaining to autoi%%unit', a %isdirected i%%une res2onse that occurs *hen the i%%une s'ste% goes a*r' and attac$s the 6od' itsel-. .utoimmune disease: An illness that occurs *hen the 6od' tissues are attac$ed 6' its o*n i%%une s'ste% . The i%%une s'ste% is a co%2le? organization *ithin the 6od' that is designed nor%all' to Nsee$ and destro'N in)aders o- the 6od', including in-ectious agents. Patients *ith autoi%%une diseases -re@uentl' ha)e unusual anti6odies circulating in their 6lood that target their o*n 6od' tissues. .:on: A long -i6er o- a ner)e cell <a neuron= that acts so%e*hat li$e a -i6er:o2tic ca6le carr'ing outgoing <e--erent= %essages. 'ateria: Single:celled %icroorganis%s *hich can e?ist either as inde2endent <-ree: li)ing= organis%s or as 2arasites <de2endent u2on another organis% -or li-e=. 'aterial: O- or 2ertaining to 6acteria. 8or e?a%2le, a 6acterial lung in-ection. 'lood +ressure: The 6lood 2ressure is the 2ressure o- the 6lood *ithin the arteries. !t is 2roduced 2ri%aril' 6' the contraction o- the heart %uscle. !tCs %easure%ent is recorded 6' t*o nu%6ers. The -irst <s'stolic 2ressure= is %easured a-ter the heart contracts and is highest. The second <diastolic 2ressure= is %easured 6e-ore the heart contracts and lo*est. A 6lood 2ressure cu-- is used to %easure the 2ressure. Ele)ation o- 6lood 2ressure is called Nh'2ertensionN. 'rain: That 2art o- the central ner)ous s'ste% that is located *ithin the craniu% < s$ull =. The 6rain -unctions as the 2ri%ar' recei)er, organizer and distri6utor o- in-or%ation -or the 6od'. !t has t*o <right and le-t= hal)es called Nhe%is2heres.N 'reat%ing: The 2rocess o- res2iration, during *hich air is inhaled into the lungs through the %outh or nose due to %uscle contraction, and then e?haled due to %uscle rela?ation. Cam+ylobater ;e;uni: a s2ecies o- cur)ed, rod:sha2ed, non:s2ore -or%ing, #ra%: negati)e %icroaero2hilic, 6acteria co%%onl' -ound in ani%al -eces._+` !t is one o- the %ost co%%on causes o- hu%an gastroenteritis in the *orld. 8ood 2oisoning caused 6' Ca%2'lo6acter s2ecies can 6e se)erel' de6ilitating 6ut is rarel' li-e:threatening. !t has 6een lin$ed *ith su6se@uent de)elo2%ent o- #uillain:BarrD s'ndro%e <#BS=, *hich usuall' de)elo2s t*o to three *ee$s a-ter the initial illness. Cerebros+inal fluid: A *ater' -luid, continuousl' 2roduced and a6sor6ed, *hich -lo*s in the )entricles <ca)ities= *ithin the 6rain and around the sur-ace o- the 6rain and s2inal cord.
78 Clinial trials: Trials to e)aluate the e--ecti)eness and sa-et' o- %edications or %edical de)ices 6' %onitoring their e--ects on large grou2s o- 2eo2le. Cure: <. To heal, to %a$e *ell, to restore to good health. Cures are eas' to clai% and, all too o-ten, di--icult to con-ir%. 2. A ti%e *ithout recurrence o- a disease so that the ris$ o- recurrence is s%all, as in the 3:'ear cure rate -or %alignant %elano%a . =. Particularl' in the 2ast, a course o- treat%ent. 8or e?a%2le, ta$e a cure at a s2a. 0iagnosis: < The nature o- a disease E the identi-ication o- an illness. 2 A conclusion or decision reached 6' diagnosis. The diagnosis is ra6ies . = The identi-ication o- an' 2ro6le%. The diagnosis *as a 2lugged !,. &astrointestinal: Ad7ecti)e re-erring collecti)el' to the sto%ach and s%all and large intestines. ,eart: The %uscle that 2u%2s 6lood recei)ed -ro% )eins into arteries throughout the 6od'. !t is 2ositioned in the chest 6ehind the sternu% <6reast6oneE in -ront o- the trachea, eso2hagus, and aortaE and a6o)e the dia2hrag% %uscle that se2arates the chest and a6do%inal ca)ities. The nor%al heart is a6out the size o- a closed -ist, and *eighs a6out +>.3 ounces. !t is cone:sha2ed, *ith the 2oint o- the cone 2ointing do*n to the le-t. T*o:thirds o- the heart lies in the le-t side o- the chest *ith the 6alance in the right chest. See the entire de-inition o- (eart ,eart rate: The nu%6er o- heart 6eats 2er unit ti%e, usuall' 2er %inute. The heart rate is 6ased on the nu%6er o- contractions o- the )entricles <the lo*er cha%6ers o- the heart=. The heart rate %a' 6e too -ast < tach'cardia = or too slo* < 6rad'cardia =. The 2ulse is 6ulge o- an arter' -ro% the *a)e o- 6lood coursing through the 6lood )essel as a result o- the heart 6eat. The 2ulse is o-ten ta$en at the *rist to esti%ate the heart rate. See the entire de-inition o- (eart rate Immune: Protected against in-ection. The Latin i%%unis %eans -ree, e?e%2t. Immune system: A co%2le? s'ste% that is res2onsi6le -or distinguishing us -ro% e)er'thing -oreign to us, and -or 2rotecting us against in-ections and -oreign su6stances. The i%%une s'ste% *or$s to see$ and $ill in)aders. Infetion: The gro*th o- a 2arasitic organis% *ithin the 6od'. <A 2arasitic organis% is one that li)es on or in another organis% and dra*s its nourish%ent there-ro%.= A 2erson *ith an in-ection has another organis% <a Nger%N= gro*ing *ithin hi%, dra*ing its nourish%ent -ro% the 2erson. 79 Knee: The $nee is a 7oint *hich has three 2arts. The thigh 6one <the -e%ur= %eets the large shin 6one <the ti6ia= to -or% the %ain $nee 7oint. This 7oint has an inner <%edial= and an outer <lateral= co%2art%ent. The $neeca2 <the 2atella= 7oins the -e%ur to -or% a third 7oint, called the 2atello-e%oral 7oint. The 2atella 2rotects the -ront o- the $nee 7oint. #imb: The ar% or leg. #o" blood +ressure : An' 6lood 2ressure that is 6elo* the nor%al e?2ected -or an indi)idual in a gi)en en)iron%ent. Lo* 6lood 2ressure is also re-erred to as h'2otension. -usle: Muscle is the tissue o- the 6od' *hich 2ri%aril' -unctions as a source o- 2o*er. There are three t'2es o- %uscle in the 6od'. Muscle *hich is res2onsi6le -or %o)ing e?tre%ities and e?ternal areas o- the 6od' is called Ns$eletal %uscle.N (eart %uscle is called Ncardiac %uscle.N Muscle that is in the *alls o- arteries and 6o*el is called Ns%ooth %uscle.N -yelin: The -att' su6stance that co)ers and 2rotects ner)es. M'elin is a la'ered tissue that sheathes the a?ons <ner)e -i6ers=. This sheath around the a?on acts li$e a conduit in an electrical s'ste%, ensuring that %essages sent 6' a?ons are not lost en route. !t allo*s e--icient conduction o- action 2otentials do*n the a?on. M'elin consists o- 5>H li2ids <cholesterol and 2hos2holi2id= and />H 2roteins. !t is 2roduced 6' oligodendroc'tes in the central ner)ous s'ste%. Ner!e: A 6undle o- -i6ers that uses che%ical and electrical signals to trans%it sensor' and %otor in-or%ation -ro% one 6od' 2art to another.. Neurologial: (a)ing to do *ith the ner)es or the ner)ous s'ste%. Onset: !n %edicine, the -irst a22earance o- the signs or s'%2to%s o- an illness as, -or e?a%2le, the onset o- rheu%atoid arthritis . There is al*a's an onset to a disease 6ut ne)er to the return to good health. The de-ault setting is good health. Pain: An un2leasant sensation that can range -ro% %ild, localized disco%-ort to agon'. Pain has 6oth 2h'sical and e%otional co%2onents. The 2h'sical 2art o- 2ain results -ro% ner)e sti%ulation. Pain %a' 6e contained to a discrete area, as in an in7ur', or it can 6e %ore di--use, as in disorders li$e -i6ro%'algia . Pain is %ediated 6' s2eci-ic ner)e -i6ers that carr' the 2ain i%2ulses to the 6rain *here their conscious a22reciation %a' 6e %odi-ied 6' %an' -actors. Paralysis: Loss o- )oluntar' %o)e%ent <%otor -unction=. Paral'sis that a--ects onl' one %uscle or li%6 is 2artial 2aral'sis, also $no*n as 2als'E 2aral'sis o- all %uscles is total 2aral'sis, as %a' occur in cases o- 6otulis%. 80 Parest%esia: An a6nor%al sensation o- the s$in, such as nu%6ness, tingling, 2ric$ing, 6urning, or cree2ing on the s$in that has no o67ecti)e cause. Paresthesia is the usual A%erican s2elling and 2araesthesia the 2re-erred English s2elling. Peri+%eral: Situated a*a' -ro% the center, as o22osed to centrall' located. Peri+%eral ner!ous system 1PNS2: That 2ortion o- the ner)ous s'ste% that is outside the 6rain and s2inal cord. P%ysial t%era+y: A 6ranch o- reha6ilitati)e health that uses s2eciall' designed e?ercises and e@ui2%ent to hel2 2atients regain or i%2ro)e their 2h'sical a6ilities. Ph'sical thera2ists *or$ *ith %an' t'2es o- 2atients, -ro% in-ants 6orn *ith %usculos$eletal 6irth de-ects, to adults su--ering -ro% sciatica or the a-ter: e--ects o- in7ur', to elderl' 2ost:stro$e 2atients. Plasma: The li@uid 2art o- the 6lood and l'%2hatic -luid, *hich %a$es u2 a6out hal- o- its )olu%e. Plas%a is de)oid o- cells and, unli$e seru%, has not clotted. Blood 2las%a contains anti6odies and other 2roteins. !t is ta$en -ro% donors and %ade into %edications -or a )ariet' o- 6lood:related conditions. So%e 6lood 2las%a is also used in non:%edical 2roducts. Plasma+%eresis: A 2rocedure designed to de2lete the 6od' o- 6lood 2las%a <the li@uid 2art o- the 6lood= *ithout de2leting the 6od' o- its 6lood cells. Bhole 6lood is re%o)ed -ro% the 6od', the 2las%a is se2arated -ro% the cells, the cells are sus2ended in saline, a 2las%a su6stitute or donor 2las%a=, and the reconstituted solution %a' 6e returned to the 2atient. The 2rocedure is used to re%o)e e?cess anti6odies -ro% the 6lood in lu2us, %ulti2le sclerosis, %ulti2le %'elo%a, etc. Plas%a2heresis carries *ith it the sa%e ris$s as an' intra)enous 2rocedure. The ris$ o- in-ection increases *ith the use o- donor 2las%a, *hich %a' carr' )iral 2articles des2ite screening 2rocedures. The 2rocedure is done in a clinic or hos2ital. Protein: A large %olecule co%2osed o- one or %ore chains o- a%ino acids in a s2eci-ic order deter%ined 6' the 6ase se@uence o- nucleotides in the &"A coding -or the 2rotein. Proteins: Large %olecules co%2osed o- one or %ore chains o- a%ino acids in a s2eci-ic order deter%ined 6' the 6ase se@uence o- nucleotides in the &"A coding -or the 2rotein. Rela+se: The return o- signs and s'%2to%s o- a disease a-ter a 2atient has en7o'ed a re%ission . 8or e?a%2le, a-ter treat%ent a 2atient *ith cancer o- the colon *ent into re%ission *ith no sign or s'%2to% o- the tu%or, re%ained in re%ission -or 1 'ears, 6ut then su--ered a rela2se and had to 6e treated once again -or colon cancer. Residual: So%ething le-t 6ehind. Bith residual disease, the disease has not 6een eradicated. 81 Res+iratory: (a)ing to do *ith res2iration, the e?change o- o?'gen and car6on dio?ide. 8ro% the Latin re: <again= R s2irare <to 6reathe= U to 6reathe again. Sensory: Relating to sensation , to the 2erce2tion o- a sti%ulus and the )o'age %ade 6' inco%ing < a--erent = ner)e i%2ulses -ro% the sense organs to the ner)e centers. S+inal ord: The %a7or colu%n o- ner)e tissue that is connected to the 6rain and lies *ithin the )erte6ral canal and -ro% *hich the s2inal ner)es e%erge. Thirt':one 2airs o- s2inal ner)es originate in the s2inal cordI 9 cer)ical , +. thoracic , 3 lu%6ar, 3 sacral, and + cocc'geal. The s2inal cord and the 6rain constitute the central ner)ous s'ste% < C"S =. The s2inal cord consists o- ner)e -i6ers that trans%it i%2ulses to and -ro% the 6rain. Li$e the 6rain, the s2inal cord is co)ered 6' three connecti)e:tissue en)elo2es called the %eninges . The s2ace 6et*een the outer and %iddle en)elo2es is -illed *ith cere6ros2inal -luid < CS8 =, a clear colorless -luid that cushions the s2inal cord against 7arring shoc$. Also $no*n si%2l' as the cord. S+inal ta+: Also $no*n as a lu%6ar 2uncture or NLPN, a s2inal ta2 is a 2rocedure *here6' s2inal -luid is re%o)ed -ro% the s2inal canal -or the 2ur2ose o- diagnostic testing. !t is 2articularl' hel2-ul in the diagnosis o- in-la%%ator' diseases o- the central ner)ous s'ste%, es2eciall' in-ections, such as %eningitis. !t can also 2ro)ide clues to the diagnosis o- stro$e , s2inal cord tu%or and cancer in the central ner)ous s'ste%. Stage: As regards cancer , the e?tent o- a cancer, es2eciall' *hether the disease has s2read -ro% the original site to other 2arts o- the 6od'.. Steroid: A general class o- che%ical su6stances that are structurall' related to one another and share the sa%e che%ical s$eleton <a tetrac'clic c'clo2enta_a`2henanthrene s$eleton=. Stro*e : The sudden death o- so%e 6rain cells due to a lac$ o- o?'gen *hen the 6lood -lo* to the 6rain is i%2aired 6' 6loc$age or ru2ture o- an arter' to the 6rain. A stro$e is also called a cere6ro)ascular accident or, -or short, a C,A. Surgery: The *ord Nsurger'N has %ulti2le %eanings. !t is the 6ranch o- %edicine concerned *ith diseases and conditions *hich re@uire or are a%ena6le to o2erati)e 2rocedures. Surger' is the *or$ done 6' a surgeon. B' analog', the *or$ o- an editor *ielding his 2en as a scal2el is s -or% o- surger'. A surger' in England <and so%e other countries= is a 2h'sicianCs or dentistCs o--ice. Syndrome: A set o- signs and s'%2to%s that tend to occur together and *hich re-lect the 2resence o- a 2articular disease or an increased chance o- de)elo2ing a 2articular disease. Trigger: So%ething that either sets o-- a disease in 2eo2le *ho are geneticall' 2redis2osed to de)elo2ing the disease, or that causes a certain s'%2to% to occur in a 82 2erson *ho has a disease. 8or e?a%2le, sunlight can trigger rashes in 2eo2le *ith lu2us. 6iral: O- or 2ertaining to a )irus. 8or e?a%2le, NM' daughter has a )iral rash .N 6iral infetion: !n-ection caused 6' the 2resence o- a )irus in the 6od'. &e2ending on the )irus and the 2ersonCs state o- health, )arious )iruses can in-ect al%ost an' t'2e o- 6od' tissue, -ro% the 6rain to the s$in. ,iral in-ections cannot 6e treated *ith anti6ioticsE in -act, in so%e cases the use o- anti6iotics %a$es the in-ection *orse. The )ast %a7orit' o- hu%an )iral in-ections can 6e e--ecti)el' -ought 6' the 6od'Cs o*n i%%une s'ste% , *ith a little hel2 in the -or% o- 2ro2er diet, h'dration, and rest. As -or the rest, treat%ent de2ends on the t'2e and location o- the )irus, and %a' include anti:)iral or other drugs. 6irus: A %icroorganis% s%aller than a 6acteria, *hich cannot gro* or re2roduce a2art -ro% a li)ing cell. A )irus in)ades li)ing cells and uses their che%ical %achiner' to $ee2 itsel- ali)e and to re2licate itsel-. !t %a' re2roduce *ith -idelit' or *ith errors <%utations=: this a6ilit' to %utate is res2onsi6le -or the a6ilit' o- so%e )iruses to change slightl' in each in-ected 2erson, %a$ing treat%ent %ore di--icult. 6iruses: S%all li)ing 2articles that can in-ect cells and change ho* the cells -unction. !n-ection *ith a )irus can cause a 2erson to de)elo2 s'%2to%s. The disease and s'%2to%s that are caused de2end on the t'2e o- )irus and the t'2e o- cells that are in-ected. 83 RE8ERENCES Brunner and Suddarth0s Medical and Surgical "ursing ele)enth edition Patho2h'siolog' / rd edition 6' Tho%as J. "o*a$ Assess%ent 6' Li22incott Billia%s and Bil$ins htt2ILLen.*i$i2edia.orgL*i$iLCa%2'lo6acterX7e7uni htt2ILL***.a6out:guillain:6arre.co%L htt2ILL***.cehs.siu.eduL-i?L%ed%icroLc%ir.ht% htt2ILL***.a6out:ca%2'lo6acter.co%Lca%2'lo6acterXs'%2to%sXris$s htt2ILL***.%edicinenet.co%Lguillain:6arreXs'ndro%eLarticle.ht% htt2ILL***.direct:%s.orgL2d-LMolecularMi%icr'OtherL#illianBarrMolMi%icr'.2d- htt2ILL***.%icro6iolog'6'tes.co%L6logL.>>9L>+L/>Lho*:ca%2'lo6acter:7e7uni:sur)i)es: *ithin:cellsL htt2ILL***.%icro6iolog'6'tes.co%L6logL.>>9L>+L/>Lho*:ca%2'lo6acter:7e7uni:sur)i)es: *ithin:cellsL htt2ILLen.*i$i2edia.orgL*i$iLM'elinXsheath htt2ILL***.dr$aslo*.co%Lht%lL6loodXcellXcounts.ht%l htt2ILL***.scri6d.co% htt2ILL***.nursingcri6.co% 84