Immunology test

Test

Patient value

Normal value

IgA

169

82 - 453

IgG

701

751 - 1560

IgM

22

40 - 274

2 Microglobulin

Free

5600

3.3 19.4 mg/L

Free

19.1

5.7 26.3 mg/L

293.19

8.47

< 2.7 mg/L

0.26 1.65

Serum Protein Electrophoresis (SPEP or SPE)

Serum immunofixation (IFE)

(pattern)

(mutation)

 (molecular weight)

(acrylamide monomer)

(covalent bond) 2 (bi-functional compound)

N,N'- (N,N'-methylene
bisacrylamide )

(sieving effect)

(native protein)

(non-dissociating buffer non-denaturing

buffer) (Tris-HCl)

(
)

5 - 15

molecular sieve

protein electrophoresis
(pattern)

albumin, 1-globulin, 2-globulin, -globulin -globulin

band

band

agammaglobulinemia
band

peak

hypogammaglobulinemia
-globulin

IgG (
IgG -globulin

fraction)

 ( IgG )

immunoelectrophoresis (IEP)


5 albumin,
a1 globulin, a2 globulin, b globulin g globulin
Immunoglobulin

globulin

paraproteinemia

band
densitometry spike Monoclonal
spike M-spike M-protein

Serum immunofixation (IFE)



MM WHO 2008
Symptomatic plasma cell myeloma 3
1. M-protein
2. clonal plasma cells
plasmacytoma
3.

lytic bone lesions,

renal insufficiency, hyperviscosity, amyloidosis recurrent
infections

 MM