NaranjoAdverseDrugReactionProbabilityScale

Question

Yes No

DoNot Score
Know

1. Aretherepreviousconclusivereportsonthisreaction?

+1

2. Didtheadverseeventappearafterthesuspecteddrugwasadministered?

+2

3. Didtheadversereactionimprovewhenthedrugwasdiscontinuedora
specificantagonistwasadministered?

+1

4. Didtheadverseeventreappearwhenthedrugwasreadministered?

+2

5. Aretherealternativecauses(otherthanthedrug)thatcouldontheirown
havecausedthereaction?

+2

6. Didthereactionreappearwhenaplacebowasgiven?

+1

7. Wasthedrugdetectedinblood(orotherfluids)inconcentrationsknown
tobetoxic?

+1

8. Wasthereactionmoreseverewhenthedosewasincreasedorlesssevere
whenthedosewasdecreased?

+1

9. Didthepatienthaveasimilarreactiontothesameorsimilardrugsinany
previousexposure?

+1

10. Wastheadverseeventconfirmedbyanyobjectiveevidence?

+1

TOTALSCORE:

Modifiedfrom:NaranjoCAetal.Amethodforestimatingtheprobabilityofadversedrugreactions.Clin
PharmacolTher1981;30:239245.