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  • Placebo Effect

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    The document defines the placebo effect as a psychological impact that can have physiological outcomes. It discusses how randomized controlled trials are used to measure the placebo effect by comparing outcomes between a drug, placebo, and no treatment. Certain conditions like smoking, dementia, and hypertension seem to have little placebo effect, while others like pain may have a larger effect, especially when the patient is not told the control is a placebo or if there is a physical placebo intervention like sham acupuncture. Response bias can also influence outcomes depending on if they are measured by patient report or interview.

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    Placebo Effect

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    The document defines the placebo effect as a psychological impact that can have physiological outcomes. It discusses how randomized controlled trials are used to measure the placebo effect by comparing outcomes between a drug, placebo, and no treatment. Certain conditions like smoking, dementia, and hypertension seem to have little placebo effect, while others like pain may have a larger effect, especially when the patient is not told the control is a placebo or if there is a physical placebo intervention like sham acupuncture. Response bias can also influence outcomes depending on if they are measured by patient report or interview.

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    147 views9 pages

    Placebo Effect

    Uploaded by

    kngs12345
    The document defines the placebo effect as a psychological impact that can have physiological outcomes. It discusses how randomized controlled trials are used to measure the placebo effect by comparing outcomes between a drug, placebo, and no treatment. Certain conditions like smoking, dementia, and hypertension seem to have little placebo effect, while others like pain may have a larger effect, especially when the patient is not told the control is a placebo or if there is a physical placebo intervention like sham acupuncture. Response bias can also influence outcomes depending on if they are measured by patient report or interview.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    of 9

    The Placebo Effect

    Unit 5 : Asynchronous 9
    Session #109
    K Benker MD MPH

    Learning objective:
    1. To define the placebo effect

    Placebo: a harmless pill, medicine, or procedure prescribed more for


    the psychological benefit to the patient than for any physiological
    effect.
    Placebo effect: Does it exist or not?

    Randomized Controlled Trials

    May or may not be placebo

    RCT with placebo and nothing

    Placebo

    Nothing

    Measuring the Placebo Effect


    DRUG

    Effect of drug

    PLACEBO
    Effect of placebo

    NOTHING

    Measuring the Placebo Effect* (cont)


    No effect

    Smoking
    Dementia
    Obesity
    Hypertension
    Insomnia
    Anxiety

    Larger effect
    Patient not told control =
    placebo
    Physical intervention
    (e.g. sham acupuncture)

    Response bias?
    Outcome measured by
    patient report
    Outcome measured by
    interview

    *Hrbjartsson A, Gtzsche PC, Cochrane Collaboration, 2010

    Test yourself
    Which of the following best defines placebo
    effect?
    A. The difference in outcomes between an
    intervention being tested and a placebo
    B. The difference in outcomes between a
    placebo and no intervention
    C. A psychological impact on a physiologic
    outcome
    D. A physiologic change based on a belief

    Test yourself
    Which of the following best defines placebo
    effect?
    A. The difference in outcomes between an
    intervention being tested and a placebo
    B. The difference in outcomes between a
    placebo and no intervention
    C. A psychological impact on a physiologic
    outcome
    D. A physiologic change based on a belief

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