Professional Documents
Culture Documents
Mohamed El Rouby
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Management of Alopecia
ﻌ An Overview:
Anatomy and Physiology
Androgenetic Alopecia
Classification Systems
Medical Therapy
Surgical Therapy
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Hair
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Scalp Layers
S:skin
C: subcutaneous
tissues, connective
tissue,
A: aponeurosis,
L: loose areolar
tissue,
P: periosteum.
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Hair Follicles
Embryonic development
at 9-12 weeks
Ectoderm
Hair matrix cells
Melanocytes
Mesoderm
Erector pili
Dermal papilla
Follicular Sheath
Blood Vessels
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Hair Shaft
Cuticle
Medulla
Cortex
Sheath
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Hair Density
5 million follicles
100,000-150,000 on
the scalp
Birth: 1135/cm2
1 year: 795/cm2
20-30: 615/cm2
30-50: 485/cm2
80-90: 435/cm2
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Follicular Units
1-4 terminal hairs
1-2 vellus hairs
Sebaceous glands
Erector pili muscles
Blood vessels
Nerves
Connective tissue
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Types of Alopecia
ﻌ Androgenetic Alopecia
ﻌ Alopecia Areata
ﻌ Cicatricial Alopecia
ﻌ Traumatic Alopecia
ﻌ Diffuse Alopecia
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Androgenetic Alopecia
increased telogen
Increased latency
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Androgenetic Alopecia
Autosomal dominant –
variable penetrance
30% of white men by
age 30
50% of white men by
age 50
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Androgenetic Alopecia
ﻌ Site-specific action of androgens
Pubic/axillary/chest/beard:
vellusterminal
Scalp: terminalvellus
ﻌ Men—testosterone
Women—adrenal androgens
ﻌ 5-alpha reductase
Testosteronedihydrotestosterone
ﻌ Why the pattern of hair loss?
Increased follicle susceptibility
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Medical Therapy
Minoxidil Finasteride
Antihypertensive Specifically inhibits
5-alpha reductase,
Side effect: hyper-
type 2
trichosis Lowers dihydro-
Topical 2%, 5% testosterone levels
Stop progression 1mg/day
and reverse Side effect:
changes decreased libido
Delayed onset Not used in women
Prolonged use
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Why treat?
Lower self-esteem
Mental distress
Stereotypes
Older
Weaker
Less productive
Less attractive
Less virile
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Motivations?
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Type II
Type III
Type IV
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Age
Is NOT a contra-
indication for
surgery
Established pattern
Hair color
Co-existing medical
conditions
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Surgical Therapy
Scalp reduction
Scalp flaps
Hair grafting
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Scalp Reduction
Unger and Unger, 1978
Many patterns
Sagittal midline ellipse
―Y‖
Lateral pattern
Transverse ellipse
Crescent ellipse
―S‖, ―J‖, ―C‖, ―U‖, ―T‖,
―I‖
Easy to perform
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Scalp Reduction--Pitfalls
Tension ―Stretch-back‖
Excessive reduction Tendency for the
Tissue necrosis, remaining bald
widened scar scalp to expand
Raposio & after a reduction
Nordstrom 10-50% of the
500-1,500 gr reduction
Galeotomies 2 months
40% reduction in
tension
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Scalp extenders
Frechet, 1993
1mm thick silastic,
two rows titanium
hooks
200% stretch
Memory
Effect: negative
stretch-back
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Nordstrom Suture
Nordstrom et al., 2001
Silicone polymer
suture, 2mm
diameter, cutting
needle
Running, buried,
mattress suture
Negative stretch-back
3x greater than with
extenders
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Tissue Expanders
Increases total hair-
bearing surface area
Placement/Incisions
Filling
Useful in conjunction
with scalp
reductions or scalp
flaps
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Scalp Flaps
Lateral
Temporoparietal
Occipital (TPO),
AKA Juri
Preauricular
Free flap
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Juri Flap
Uses: recreate
frontal hairline
Parietal branch of
superficial
temporal artery
Flap
Pedicle: 2-2.5cm
Width: 4-6cm
Length: 23-25cm
Delay
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Juri Flap
Design hairline
Elevate flap
Close donor site
Inset flap
Resect bald scalp
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Hair grafting
Okura, 1939
Orentreich, 1959
Punch graft
Strip graft
Follicular-unit graft
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Punch grafting
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Punch grafting
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Strip Grafting
Vallis, 1964
Free composite graft
Reconstruct frontal
hairline
Dimensions
Length
Width
Un-operated
Previous
operation
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Strip Grafting
Vallis, 1964
Free composite graft
Reconstruct frontal
hairline
Dimensions
Length
Width
Un-operated
Previous
operation
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Follicular-unit Grafting
Minigrafts
3-4 hairs/graft
Micrografts
1-2 hairs/graft
Barrera’s technique
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Follicular-unit Grafting
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Follicular-unit Grafting
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Follicular-unit Grafting
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Follicular-unit Grafting
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Follicular-unit Grafting
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Follicular-unit Grafting
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Follicular-unit Grafting
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Follicular-unit Grafting
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Follicular-unit Grafting
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Revision Surgery
Removal
Repositioning
Reduction
Addition
Scar revision
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Conclusion
ﻌ Wide variety of methods for the correction
of alopecia
ﻌ Don’t forget medical management
ﻌ Individualize treatment plans
ﻌ Counseling, Counseling, Counseling