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Mohamed El Rouby
Copyrighted by dr. Mohamed El Rouby

Management of Alopecia
‫ﻌ‬ An Overview:
 Anatomy and Physiology
 Androgenetic Alopecia

 Classification Systems

 Medical Therapy

 Surgical Therapy
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Hair
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Scalp Layers
 S:skin
 C: subcutaneous
tissues, connective
tissue,
 A: aponeurosis,
 L: loose areolar
tissue,
 P: periosteum.
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Blood and Nervous Supply


Frontal
 Supratrochlear
 Supraorbital
Temporal
 Superficial temporal
 Zygomaticotemporal
Parietal
 Retroauricular
 Auriculotemporal/Great
Auricular/Lesser
Occipital
Occipital
 Occipital
 Greater occipital
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Hair Follicles
Embryonic development
at 9-12 weeks
Ectoderm
 Hair matrix cells

 Melanocytes

Mesoderm
 Erector pili

 Dermal papilla

 Follicular Sheath

 Blood Vessels
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Hair Shaft
Cuticle
Medulla
Cortex
Sheath
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Hair Density
5 million follicles
100,000-150,000 on
the scalp
Birth: 1135/cm2
1 year: 795/cm2
20-30: 615/cm2
30-50: 485/cm2
80-90: 435/cm2
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Follicular Units
1-4 terminal hairs
1-2 vellus hairs
Sebaceous glands
Erector pili muscles
Blood vessels
Nerves
Connective tissue
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Hair Growth Cycle


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Types of Alopecia
‫ﻌ‬ Androgenetic Alopecia
‫ﻌ‬ Alopecia Areata
‫ﻌ‬ Cicatricial Alopecia
‫ﻌ‬ Traumatic Alopecia
‫ﻌ‬ Diffuse Alopecia
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Androgenetic Alopecia

Male Pattern Balding


Female Pattern Balding
Pathophysiology
 Miniaturization of
follicles
 Decreased anagen/

increased telogen
 Increased latency
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Androgenetic Alopecia
Autosomal dominant –
variable penetrance
30% of white men by
age 30
50% of white men by
age 50
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Androgenetic Alopecia
‫ﻌ‬ Site-specific action of androgens
 Pubic/axillary/chest/beard:
vellusterminal
 Scalp: terminalvellus
‫ﻌ‬ Men—testosterone
Women—adrenal androgens
‫ﻌ‬ 5-alpha reductase
 Testosteronedihydrotestosterone
‫ﻌ‬ Why the pattern of hair loss?
 Increased follicle susceptibility
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Norwood Classification (men)


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Ludwig Classification (Women)


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Medical Therapy
Minoxidil Finasteride
 Antihypertensive  Specifically inhibits
5-alpha reductase,
 Side effect: hyper-
type 2
trichosis  Lowers dihydro-
 Topical 2%, 5% testosterone levels
 Stop progression  1mg/day
and reverse  Side effect:
changes decreased libido
 Delayed onset  Not used in women

 Prolonged use
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Why treat?
Lower self-esteem
Mental distress
Stereotypes
 Older

 Weaker

 Less productive

 Less attractive

 Less virile
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Patient evaluation for surgery


Expectations?

Motivations?
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Patient evaluation for surgery


Donor Hair
 Type I

 Type II

 Type III

 Type IV
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Patient evaluation for surgery

Age
 Is NOT a contra-
indication for
surgery
 Established pattern
 Hair color

 Co-existing medical
conditions
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Surgical Therapy

 Scalp reduction

 Scalp flaps

 Hair grafting
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Scalp Reduction
Unger and Unger, 1978
Many patterns
 Sagittal midline ellipse
 ―Y‖
 Lateral pattern
 Transverse ellipse
 Crescent ellipse
 ―S‖, ―J‖, ―C‖, ―U‖, ―T‖,
―I‖
Easy to perform
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Scalp Reduction--Pitfalls
Tension ―Stretch-back‖
 Excessive reduction  Tendency for the
 Tissue necrosis, remaining bald
widened scar scalp to expand
 Raposio & after a reduction
Nordstrom  10-50% of the
 500-1,500 gr reduction
 Galeotomies  2 months
 40% reduction in
tension
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Scalp extenders

Frechet, 1993
1mm thick silastic,
two rows titanium
hooks
200% stretch
Memory
Effect: negative
stretch-back
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Anchoring Galeal Flaps


Raposio, et al., 1998
Leave galea
attached to one
scalp flap
Create 3 2x3cm
galeal flaps
Suture flaps to
undersurface of
opposite galea
80-88% reduction in
stretch-back
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Nordstrom Suture
Nordstrom et al., 2001
Silicone polymer
suture, 2mm
diameter, cutting
needle
Running, buried,
mattress suture
Negative stretch-back
3x greater than with
extenders
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Tissue Expanders
Increases total hair-
bearing surface area
Placement/Incisions
Filling

Useful in conjunction
with scalp
reductions or scalp
flaps
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Scalp Flaps
Lateral

Temporoparietal
Occipital (TPO),
AKA Juri

Preauricular

Free flap
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Juri Flap
Uses: recreate
frontal hairline
Parietal branch of
superficial
temporal artery
Flap
 Pedicle: 2-2.5cm
 Width: 4-6cm
 Length: 23-25cm
Delay
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Juri Flap
Design hairline
Elevate flap
Close donor site
Inset flap
Resect bald scalp
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Free Juri Flap


Advantages
1. Avoid delay
2. Avoid revision
around pedicle
3. More natural
pattern of frontal
hair growth
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Hair grafting
Okura, 1939
Orentreich, 1959

Punch graft
Strip graft
Follicular-unit graft
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Punch grafting
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Punch grafting
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Strip Grafting
Vallis, 1964
Free composite graft
Reconstruct frontal
hairline
Dimensions
 Length
 Width
 Un-operated
 Previous
operation
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Strip Grafting
Vallis, 1964
Free composite graft
Reconstruct frontal
hairline
Dimensions
 Length
 Width
 Un-operated
 Previous
operation
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Follicular-unit Grafting
Minigrafts
 3-4 hairs/graft

Micrografts
 1-2 hairs/graft

Barrera’s technique
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Follicular-unit Grafting
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Follicular-unit Grafting
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Follicular-unit Grafting
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Follicular-unit Grafting
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Follicular-unit Grafting
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Follicular-unit Grafting
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Follicular-unit Grafting
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Follicular-unit Grafting
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Copyrighted by dr. Mohamed El Rouby

Follicular-unit Grafting
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Revision Surgery
Removal
Repositioning
Reduction
Addition
Scar revision
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Conclusion
‫ﻌ‬ Wide variety of methods for the correction
of alopecia
‫ﻌ‬ Don’t forget medical management
‫ﻌ‬ Individualize treatment plans
‫ﻌ‬ Counseling, Counseling, Counseling

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