‘Complete initial evaluation, Check capillary glucose and serurvurine ketones to confirm hyperglycemia and
ketonemia/ketonuria. Obtain blood for metabolic profil, Start lV Nuids: 1.0 L of 0.9% NaCl per hour.t
WFuids Bicarbonate Instn Regular Potassium
t + t 7 T
mares ears? IY Route Iv Rowe Esiatisn adouata
(OKA sna HHS) (OKA and HH) renal oeten (ane
Determine hycaton statis [Wo] [ Toemmatla | ‘utp = £0 i)
100] | soomit.0
1 ‘20meq | [ O1 UagEmn.
Severe carcoganse NGL. inuse | | as Vbotss
Hypovolemia’ ag shock for3 hours 0.14 Ung Buon
nt T se IV conus
| | Insulin infston. ‘Ki e3.3 mEq 1 >5.2meEqL
Aart 0.9% Hemodinanic Repent] | counts’ I
‘Nacl(10 UN) ‘monioing! oer acmenae
pressore ares Hol ian ad ge Do not ove,
pH 20-0 mEq fe bal check serum kt
Evaluate coretied Ome
‘Serum Na*t ioe IF Serum glutose oes not fall by at Until f° 2 3.3mEqt. every 2 hes,
TO ue feast 10% i rst hour, ge 0.14
= ‘Uskg 83 1V bolus, then continue:
Serna? Serumbist- Sum \ sere
ur Nat Serum Na Sera Nat
‘high orthal low DKA ¢ 3 HHS Ki=33-52mEql
| When sor gens ‘When serum gene
reaches 200 mgidl, reduce reaches 300 mid, reduce
048% NeCl 09% Nec euler sun eso gular inulin
{es0-sd0min’) ———_(@80-S00mi) (02-0.08 Ughe W, orgie | | 002-008tskgheW Keop | Gvead a0 meqKin exch
depending on ‘depending on ‘rapid-acting insulin at 0.1 ‘serum glucose between 200 liter of TY fuid fo keep serum
hyration stot hydration state Uhig SC every 2 hrs. Keop ‘and 360 mgidl until patients Kr between 4:5 mEq.
serum glucose beeen 150 metal alo.
sd 20 rll ul eeoubon
of DKA
‘When serum glucose reaches
200 mall (DKA) or 200 mata
(Hts), change 0 5% donvose
wih 0.48% NaCl a 150-260 me
‘Check eietrives, BUN, venous pH ereainine and gucasa every 2-4 fre unl sabia,
‘After resoluton of DKA oc HHS and when patients able o es, ate SC multidose
insulin regimen, To transfer from WV to SC, continue {V Insulin infusion for 1-2 hr
ator SC insulin begun to ensura adequate plasma insulin levels. In insulin natvo
patellar a5 Ung 0.8 Ung body wei pr iy and jn a8 nuded,t glucose. + anion gap" t serurn/urine Ketones and/or
+ sdrum beta“OHB, 4 pi (venous or arterial) or 4 bicarbonate
Plasma electrolytes, anion gap. gitease, creatinine, plasma osmo-
fallty. fluid baiance, level of consciousness every 24h
Precipitating factors (Table 1), Complications (Table 1)
wawas Serum iC) Aelaosie
Severe dene avo 53 pga
GH) [moattate ence 22028 ancl,
Om Nadi oo Nal Give 20 Gieioa0 iene ree peo
ren so nean, | (macnn | | Sectet, | fossil, | [ esaih Sh, | Gee)
so cotieee tae cmiaetarvcne| femttlalmmorns] | care Saintes
nypseinsions Ll aso mtitexan | (Sneinsuimanea) [Eas auuresve| | nyscktcnua | | Shoe actin
mea Tepes sc] | Meeaatseia® | | wees reat
Sas Toate ot Uys
‘Adjust rate of insulin
infusion based on anion,
Corrected plasma [Na"l! Avoid hypokalemia and
hypoatycernia
Corrected plasma [Nal
fe low: or Rate of fall oF
jis normal or high: and Rate
offal! of effective plasma,
1 ampoutest
hypokalemia