MINI CASE STUDY

Solve at least (3) Three cases in the following:

OPTIONAL ONLY:
You can get additional bonus points if you can submit a diagram of Classical, Alternative and
Lectin pathway (hand written with colors).
BONUSES: 15 POINTS QUIZ
5 POINTS SHIFTING EXAM
CASE 1
A 5-month-old boy is referred to a paediatrician after suffering with recurrent
infections since his birth. His mother has noticed increased irritability. Blood
tests reveal a neutrophil count of 350/L. NBT test is normal.
CASE 2
A 20-year-old man presents to his GP with signs of a mild pneumonia. The
patient states he has had several similar episodes in the past. Further investigations
by an immunologist reveal the patient has a genetic condition caused by a
mutation of MHC III.
CASE 3
A 45-year-old man undergoes a heart transplant due to end-stage heart failure.
Seventy-two hours after the operation, the patient shows signs of organ rejection
which is resistant to corticosteroid therapy. A mouse monoclonal antibody
is administered to save the transplant.
CASE 4
A 56-year-old woman presents to the rheumatologist with pain in her hands.
On examination there are obvious deformities of her proximal interphalyngeal
joints and metacarpophalyngeal joints. Swan-neck deformities are seen but the
patient has retained functionality of her fingers.
CASE 5
A 45-year-old woman is referred to a hepatologist after suffering an episode of
jaundice, fatigue and fever. Liver function tests reveal an increased AST. Biopsy
of the liver reveals cirrhosis and an autoimmune pathology is suspected.
CASE 6
A 34-year-old man who has been taking amoxicillin for pneumonia has developed
tiredness and palpitations since taking the medication. Blood tests reveal a
normocytic anaemia and direct antiglobulin test is positive.

Note:
Deadline of submission on January 5-6, 2015 at the Faculty room. Just clip
everything using a metal clamp. No need for soft copies.
NO COPYING PLEASE

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