Spectrum of Nephrotic / Nephritic Syndrome

Pure Nephrotic
MCD No IC deposit
Membranous GN
IC sbendothelial deposit -> Thickening of
BM
Mesangial Proliferation GN
IC mesangial deposit -> Mesangial
proliferation

Pure Nephritic
Acute Glomerulonephritis
IC subepithelial deposit
1. may injure podocyte -> Proteinuria
2. may injure basement membrane -> Endothelial
proliferation
2 Mesangial proliferative GN -> Resolution
Lupus nephritis class 3&4

Nephritonephrotic
IgA nephropathy
recurrent hematuria
FSGS
Heavy proteinuria w/ Hyperension &
Hematuria
Membranoproliferative GN
endothelial membrane proliferation
?: Nephritic
?? (Mesangial prolif. C): Nephrotc

Crescentic Glomerulonephritis ** 6
Rapidly Progressive GN
Non-RPGN
Credited by Mew

Severe nephritic syndromeAcute Renal Failure (Abrupt onset)

?C? Underlying disease
C Lupus nephritis, MPGN, AGN