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    large animal

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    © All Rights Reserved
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    8 views1 page

    Large Animal

    Uploaded by

    GirirajPurohit
    large animal

    Copyright:

    © All Rights Reserved
    Download as PDF or read online from Scribd
    Flag for inappropriate content
    of 1
    Various disorders have discussed under brief descriptions asfollows: Cerebellar Abiotrophy (CA) Synony Cerebellar cortical abiotrophy (CCA) ‘Common symptoms: + In most cases foals appear normal at birth, and symptoms generally become noticeable after four months or may be after one year of birth + Horses affected with Cerebellar Abiotrophy tend to startle easily and often fall. + Common symptoms include head tremor, a lack of balance and other neurological issues. + Affected horses may develop a wide-based stance of the forelegs and difficulty ising from a reclining position. Genetics: Cerebellar Abiotrophy (CA) has a recessive trait Of inheritance, which means that only horses that carry two copies of the mutation (CA/CA) will be affected, and Carrier horses (N/CA) will not develop the disease but may pass ton to their offspring, Table 1: Inheritance pattern for Autosomal Recessive trait (Labokiin, 2007) Sire Dam | Offspring clear | x | clear | 100% Clear clear | x | Carer | Sox Clear + 50% carers Clear | x | affected | 100% carriers amir | x | clear — | Sow clear + 50% caries Camier | x | Carrie | 259% clear + 25% affected + 50% caries * Carer | x | affected | 50% carers + 50% affected Affected | x | clear * | 100% carriers ‘Affected | x | Carrier | S05 carers + 50% affected Affected | x | afected | 100% atected Carriers have only one copy of the mutation so they do not express the trai 28 + The mutation can be passed down, sometimes for several generations, without the trait being expressed even though the mutation is present in a horse's genotype. *+ Both parents must be carriers and each must pass along copy of the mutation in order for afoal to be affected Differential diagnosis: Cerebellar Abiotrophy is sometimes confused with Wobbler's syndrome, Equine Protozoal Myeloencephalitis and injury-related problems Prevention and Controll: Cerebellar Abiotrophy can be prevented by selective breeding approach, This disorders ‘ot curable; however, genetic testing can detect carriers horse, therefore genetic testing is important to control the spread of the disease, Congenital Stationary Night Blindness (CSNB) Breed affected: Appaloosas breed are mostly affected Description: Impaired or absent night vision. This condition makes the horses less visible particularly in low intensity light. CSNB is a form of non-progressive night blindness. There is more than one form of CSNB that can ‘occur in horses. There is a common form of CSNB caused by the TRPMA gene, also known as Leopard Complex, which causes “appaloosa” patterns, Mutation TRPM1 gene impairs the function of rods in the eyes that allow animals to see better in the dark. The eye itself is not affected, but a pathway from the eye to the brain is impaired, Ifthe horse have night blind since birth, then itis

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