A simple method for estimating 24 h urinary sodium and potassium ex... ...

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http://www.ncbi.nlm.nih.gov/pubmed/8432042

Abstract
Clin Exp Pharmacol Physiol. 1993 Jan;20(1):7-14.

A simple method for estimating 24 h urinary sodium and potassium

excretion from second morning voiding urine specimen in adults.
Kawasaki T 1, Itoh K, Uezono K, Sasaki H.

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Erratum in
Clin Exp Pharmacol Physiol 1993 Mar;20(3):199.

Abstract
1. An assessment was made of the extent sodium (Na) and potassium (K) intake can be estimated from
Na, K and creatinine (Cr) content of a second morning voiding urine (SMU) specimen collected within 4 h
after the first voiding upon awakening but before breakfast in 159 clinically healthy, free-living individuals
(20-79 years). The SMU and the rest of 24 h urine specimens for a 3-5 day period were collected. 2.
The following equations for estimating 24 h urinary Na (24HUNaV) and K (24HUKV) excretions were
developed, and the accuracy and the reliability of these equations were evaluated. Estimated value of
24HUNaV (mEq/day) = 16.3 square root of XNa; estimated value of 24HUKV (mEq/day) = 7.2 square
root of XK, where XNa (or XK) = SMUNa (or SMUK)/SMUCr x predicted 24 h urinary Cr excretion. 3.
Highly statistically significant correlations were detected between the values estimated and measured for
both Na (r = 0.728, P < 0.001, n = 159) and K (r = 0.780, P < 0.001, n = 159). 4. These equations were
applied to Group 1 subjects, who collected the urine for a single day, and to Group 2, for 3 days. The
correlation coefficients between the values estimated and measured for Na and K were 0.531 and 0.443
in Group 1, and 0.821 and 0.590 in Group 2, respectively. No statistically significant differences were
observed. 5. The SMU specimens provide a satisfactory alternative to both 24HUNaV and 24HUKV in
adults for extensive epidemiological surveys but also for clinical application.
PMID: 8432042 [PubMed - indexed for MEDLINE]

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17/11/2014 12:11 a.m.

A simple method for estimating 24 h urinary sodium and potassium ex... ...

2 de 2

http://www.ncbi.nlm.nih.gov/pubmed/8432042

17/11/2014 12:11 a.m.