Drug Name

1. Celecoxib

(Celebrex)
200mg/cap 1 cap
PRN for pain
-antiinflammatory
-NSAID

Mechanism of Action
-Selectively inhibits
enzymatic activity of
cyclooxygenase-2
(COX -2) thereby
inhibiting the
interactions of
prostaglandins
resulting in reduced
pain felt

Indication

Contraindicati
on
-Acute pain Hypersensitivity
to aspiring,
NSAIDs or
sulfonamides
-Perioperative
pain in the
setting of
CABG surgery

Side Effects
-Diarrhea
-Dyspepsia
-Headache
-Hypertension
-URTI

Nursing
Responsibilities
-Administer without
regard for food for
dosages up to
200mg
-Use cautiously in
patients with HPN
-Monitor the
patients blood
pressure closely
throughout the
therapy because
celecoxib may start
or worsen HPN
-Evaluate
therapeutic
response