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Pathophysiology Diabetes Mellitus
Pathophysiology Diabetes Mellitus
Genetics
Intracellular
Hypoglycemi
a
Glucogenesis
and
Gluconeogenes
is
Breakdown
of fats
High
levels of
ketones
Diabetic
Ketoacido
sis
Insulin
Insufficiency
Obesity
Reduced
tissue uptake
of glucose
Extracellular
Hyperglycemia
Hyperosmot
ic plasma
Decreased
Protein
Synthesis
cachexia
lethargy
polyphagia
Decreased
Gamma
Globulins
susceptibility
to
Dehydratio
n of cells
Hyperglyce
mic coma
Blood
glucose
> renal
threshol
d
glucosori
a
Osmotic
diuresis
-polyuria
-polydipsia
-hypokalemia
hyponatremi
a