It typically is located in the retrosternal area and generally may last 10 to 30
minutes; Ischemic chest pain is often related to exertion or emotional stress, typically relived by rest, and may be accompanied by dyspnea, diaphoresis, and nausea. Chest pain lasting a few seconds usually is not of cardiac origin. Acute pericarditis may also cause chest pain that typically is located in the retrosternal area. The pain is worsened by cough, deep inspiration (pleuritic pain), and supine position; it is relieved by the patient sitting up and leaning forward. A history of a recent viral infection may precede the occurrence of pericarditis. Physical examination may reveal the presence of a pleural rub and tachycardia. A pericardial rub may be present in 85% of the cases; Aortic dissection typically presents with severe, sharp, or tearing abrupt-onset chest pain, often radiating to the back or to the abdomen. Hypertension is an important risk factor. On physical examination, aortic dissection may present with elevated blood pressure (49%), presence of a differential in blood pressure (31%; defined as >20 mm Hg difference between the right and left arm), or an early diastolic murmur due to acute aortic insufficiency (28%) when the dissection involves the ascending aorta and extends into the aortic valve DDx cardiac chest pain: o Ischemic heart disease; o Acute pericarditis; o Diseksi aorta; o Stenosis aorta; o Cocaine-induced