BLOOD PRESSURE REGULATION

03/11/2015

Systolic B.P > (proportional) > Cardiac Output CO

Diastolic B.P > (proportional) >Total Peripheral Resistance TPR
MEAN ARTERIAL PRESSURE:
Average of systolic and diastolic pressure

40 mmHg (extra in systole) is divided by 3 = 13 mmHg = MEAN

ARTERIAL PRESSURE
why 3? = because systole is 1/3 and diastole 2/3!!!
MEAN ARTERIAL PRESSURE VS MEAN SYSTEMIC PRESSURE
MAP > only on ARTERIAL site = 100 mmHg (healthy one)
o Arteries!!! From heart to arterioles
MSP > only on SYSTEMIC site = 6.5 mmHg
o Venous + capillary + arterioles = pressure maintained in
systemic circulation when there is not cardiac output
When heart doesnt work
VENOUS RETURN > from tissues to the heart
BLOOD PRESSURE>
CO: (SYSTOLE) depends on stroke volume SV & Heart Rate HR
STROKE VOLUME SV:
Preload: blood in ventricle before contraction
o End diastolic volume / end diastolic pressure (how much it
stretches before contraction)
o Venous Return which depends on RAP (right atrial
pressure)
FILLING PRESSURE

 1. Venomotor tone
2. Blood volume
FILLING TIME
When heart beats are very very fast! The filling
will be less; therefore, E.D.V will be less and BP
less
Contractility
o If there is less C > SV is less > CO is less > BP is less
AfterLoad > TPR
o If I give a arteriole dialator > TPR will be less > afterload will
be less >
TPR (TOTAL PERIPHERAL RESISTANCE) > DIASTOLE:

MAP = CO x TPR (these 2 are interdependant) if CO (up) > TPR

(down) and MAP (UP) or viceversa

REGULATION OF BLOOD PRESSURE

SHORT TERM (neurological)
LONG TERM (Renin Angiotensin Aldosterone Axis)
SHORT TERM>
Neurological Rg
LONG TERM >