10S “ad ates ond SHREAIS {bo After the examination périog, pass y ~ Evens een Cee numbers questions in A: Byerybody, : Answer only dé uusiricied, be Accurate, Brief and €¢ "The Central Dogma of Gbnciies is explaoes By this schcin The eonral dogma such as DNA-+RNA—Proteins i he basis 1 is meio SIC Rot witose tha led lo signet ges Can theiasis Gecurin-heploid cell? How about: Give an expatinen fe MALDNA Ge attic material. Negplenase NAM Wh orapstes i and oe seen A sea ae ofrmolecular gentiics True Gr ale. Explain briefly. variation. Truc 5 Fale. Explain x is Onsen AQ sinsie Ola EDNA: ATCBGC TIA ARTAAGGGG CTA. FA GGGAAA ATC GEG ATE T6i UL. all of tess eaences yb danelated to protein (esuming tere wing ove 42.° Do yoo thine he sequence vill ave higher Fo an Co? Explain yous anger T>€ HDS 13. merges apo utero 20; ho ary ehonoeames are vighe st heed ff ‘hroriotone ire moving each pile durng anaphase ote) -Hesisors ate (Hen, ean’ isk checkoins, Git Games ernie g see des us aié deletion, substi, trans orat ot Bur terefe ig) ale ehvomocomes how mary ae Set ENDS A 17, Mec eel regulated py tec peibarg ss iy) nets 18. QABCHEFGH is hypothetical bone a Heese mk 165 aud how many are Sister oh 20, eas thee 10 pais of Fi * wer O) ai mihaperea’qie: volved’, plaid ber roles. 46 3 Shs eo aisver B. fe, Do pot stand up NAMProieips-tONA. The or Palse Esplin your answer > e echt Poking tean MeCRLT CH SMES Bes Ah tontrot matress! pe a a ional igna enguicuiata(cowpea) chromosomes, how many ‘are homolo; eS and how man age sister chromatids ?. Y Pe nere » iiigiion with examples) inangalleles 0. F dor mating population : CO Rant ib ( ‘ If 32.calves ot un ne ABOrblood syste I i by 2 sult v 8 4 emminant I). ‘Among 2 certain group of people, the frequencies ~ “oF ABO blood geoups were found to be approximately 49% fro‘lype O, 36% for Type A, 12% for-Typé Band 3% for Type AB. : : 1, : oh, a. What are the allelic frequencies in this population? b. Froir'your answer in (a}, what percentage Of Type A are probably homoxygous? shape is dominant to constricted pad. When these traits are considered ina self- ‘4, in Garden pea, yellow cotyledon is dominant to green cotyledon and inflated pod ZL fertilized di-hybrid, the progeny appeared in the following numbers: Phenotype Numbers Green cotyledon, inflated pods 379 Yellow cotyledon, constricted pods 552 Yellow cotyledon, inflated pods 1,668 Green cotyledon, constricted pods 183 {a} Runa statistical test to determine if these outcomes agree with expectations for di- inybrid inheritance. {b) Oraw conclusions. aLb. ‘Dominance and Epistasis ie &. Genotype & Phenotype °. DNA & RNA : aa ] egress 32 fe Milosis & Meio: is 24 nes Ry YH for ae colour arid: feght of Seeds" elyare Known ina cefalnyplant Att a Tall/ Qwart Ba, Define the 1 ang 2m Laws of Mendel, Ih garden peas, tallness (T).is dominant over dwart(t),.Give the genotypes of the parents of the following crosses: i. Tall x dwaitf producing alltal pp BETES ii. Tall x tall, oducing 3 tail: 1 dwait TR til, Tall x dwarf, producing % tall: ¥% dwarf TH noe w G A 1 wR! ‘ « rl AR AP AR AR Fo R/S ewe dF 1 Rea, ww KY ae AY a” Sal Ne —. Re aR AR cial a ee Bote 2 Te te ae /ss| PA, fe (9 / ttt te"{oc 2 The Gell is made up of 2 2. Genes are carried on Instriietion: Thetworypes.of ell divisions are ‘SWyos 15, a ‘The process of producing game 13. 14, 15. Geng one aw’ Phd and 1h mere The Geoceure WAG ALAN TE 16 & The vps distanbe between two gehd loel dn a chrombsonie fs measuredlin Cento Aan- (eM) Re pee “The Extitihge of genetic material between “homologous chramosemes 16 produce Stow : “ xecnmibh rants is known as - The two common methods used in linkage analysis ~ Yeduthrady, Probability theories ate base on two types of events namely Soe 2 te. The masking Effeer whieh one gene locus has above the expression’ Of others is known as— wdayodvar ZHIas% «OF ing QREEINBLE TEENA GENE epg & aroeee corrgang aber jeg ch ereich fragment will have a ‘hodel ofthe DNA stmuetie | spermalgeyes 8) 100 pr secondary oosylés ih maize, process), ae as aes ae ib ein ace a Mauna i iS Si HE COLI” by ne SUBSE Ld ed = Se ee “The RNAS involved: scription” and ‘twansiation ‘are’a) DNA’ fepenivey, : a 26. Only, yb "RNA polymerase, b) free nucleotides, c) suger-phosphate d) ab,¢ islare needed in transcription. ‘Dic Phe genetic code ce rile bodon for synthesis of 2) DNA b) mRNA rote g) RNA 28-The cheomosomal aberration that eécurs daring separation of chrome: tits fies! Trywor false, Explain ‘29-Molédilar genetics is the science that deals with chromosomes may, lead to non, —disjunction which means what? a ChtaMIED WHA Ehrormosemes do oot SePparase on} polls -30.Hershey and. Chase proved that the D A ie made up of &¥phosphoras? b) Sulfur? e)eontguration. eu 31-The DNA con existin 2) A,B,Z b) A,B,C ©) lefihanded sffright-handed ‘configuration. 42, if'a small bacterial genome contains 2.7 x 10° base pairs, what is the size of the corresponding protein, remember the initiation and termination codons. 24 Seong fom pete ep mag Stork INTOREETEN geen winch THe MEN re eptan nte Cre Orage CFT TESCMNE |] bea Yasue . Fy \ ween \sar hedeeren | S205 #9 0U@ Bu we Gy Get bac a dA Ctrattenrams re condos3a Wan-P,, ig: leterOzvpons for a Stmoles will it produce for dae the number of types of loci? Pete 14 ang 3 h low Bametes pr ‘us? What are the Seneral mules for obtaining Oduced by an individual heterozygous for n Lew of Mendel neg Suc Unieel tees SEN Meared ce -tne ox Chpineso, MESO baad ie ‘ O€ S64 18 Zero Wad 16 cones TH Penemance OI Gene onane sea is Ze Sex Gmited VV — Abeta = 12 be jeaegenteni ae lau cy fet aes © Se gremeenin A tare Pane 6 Smarts nar sag charac ¢ a7 BYadnsm ie \ S00 RGataed ty 1405 ei eee seten ie Getty SG cu ati ae rata 4 i fey 6 etkey five (tea per:Web ce, Obafemi Awok Reductional division (Tn nooth process with no clear Ou oiscontinuity & fap? omosome.inva gametes i is - the number in a somatic cell i is-- ——~ while. W the ck chri omosdme is made. of two nuclei acid namely eis and -S8S_- 12 The 3 stages of protein ‘synthesis are 13 There are 2type of bases namely 2 14 The DNA molecules consist of a long sequence of. 15 RNA is produce in the 3 in fiotein syarnesis “and its primary function is eens WAC paced ed bin The Un ten eq Saneve Pha 70 G4 ces oy) ‘ ow duirer eaPcie Sy BAG ION A 12 “Write short notes ov th be t Renee role ‘ieee sais a, What are the cs ss tneeoneslalon? Given the Me Ge on the a lative, occurrence, ot is 008 blood groups in a ‘heeqiens Genotype AA oF AO uo) SAB. 00 evion. we Fst fre the best answer from B:1-2 (20%) “sickle ell anacine is caused by amutation where a base is changed ftom Adghine to‘Thyotihe.» 42% * Ieis the phase of the cell-cycle where the INA is replicaiéd or synlhesized, ="S boxe ~ o 33+ tn fing where there is the al fiGit Of generations, this generation js always dil 4. tneefers.to the renaturation property of the DNA. Reseeemtcs oq 5. Akind Sf molecular technique where malecles sre separaied by etecivicity in o'inedium like pet or paper according to their size or charge. Glebe PE esis . loid. @ verb 6. ‘The gones responsible for the cells to.emler the M phase of the'celbeyele. MHL 1. The process 6f transcribing Ihe genetic nucleotide code into proteins. “Trans 30 10N 5. itis the outward physical maifesiation of the genes in an oepanisns, Procbha Se 2), ‘Theamolecule-responsible for carrying: the-amino seid.into the ribosome platform. Wye A. 10. he shot sequence upstream st gene that initiates wanseription, 11. Ploidy level characterized by the.lormul 12. Itis the cell division th: Prenater Pa n- Lanonosom 4 is resgionsible for genetic recombination enabling variation ainang organisms $3, The aberration at nuclentide ieved causing changes in the nucleotide tcmposition, PALEQIT Os 14. He promulgated the theory that active humours formed in nuimerous pans of I twaasponéed through blood vessels to the semen. BE evo body’and is 1. “Hippocrates 15. polyploidy 2. Darwin 16. monasomy. 3. S phase 17. deletionah 26. mutation Sl fica DNA 9¢21.06 ihe piel on es iS ONA contains). DAA ‘a in inicrcns (| micron is 10% San lar aass of his DNA‘(1bp has a molecular mass of OOU Gallons)? C68 odes dos his DNA contain? oe ja ungnicnlie) ras a diploid .ninsbay/or22- Haw ee megaspana 21% al sulting (omnes puelesr division (huiyokinesis) of a sieyispore ‘apolat nucleus a2 2 be ‘i nial eb y0, sac (aller degeneration of nonfunctional nuclei) ve hs ah-eggetucleus, >) ‘endosperm cell “= acell oftheembryo. > 2% _ LEGER GGT e' es BaCcater nant : In the sequence AG ag AL CCS 4) POC MGAMTC TA metcGerrGe Tex rheran, XG Write the sequinc¥ 6! OA SACN GbR GA Es AS Ifthis translated to a protein after ‘pli nthe dincleatide-innron repeat (QA) how'many amino-acids would'there be? ¢ - Would you expect a high Tra for this DNA? FA phesiatyne ratio of 3:1 is the offspring of « mating of we organisms hete-czygous fora single. Wallis expected whien (a) the alee: sewregate ducing, meiosis (b) each allele contains two mutations (e) the alleles age identical (cl) only zecessive traits are scored. F. Ina population of 100 pigs with a complete dominant gene W (white colour), 90'are white and 10 gre albino, es 4G, oy & i f=. how 52 What is the frequency of tse dominant and recessive genes? f \ 2. Calculate the number of individuals with dominant gene. henarygaus and recessive genes ie fa io: lal (ee S10 shee GEV OF AGHICL LITE Sine i peuple fe “AIM What are he Hequencies expen Stine wellith Dhue ini, ln eu sequins? ofa sesclnked Hist an Catterse Bp OS 59% Noir ge inpnnebiey S propoctian of marciges are buthudbaad and wig Enlai tr suse for question () AL. Gilgen the fillowing a the relotivcireuerence wf she Ab) at J. Resansinsecist papnation ee eats othe hes clio spe atetes ; ‘ ope Gerisine ‘ Aveeno f Tees. 9 Saber 7 S20 Fal he msrseln vty we. ezou ate you Yves a tt umber, sine on wen akira sugaiae and yes rear Sensht unr hiveay oe nerd quasioot GO NUE astnerbathaid diate ae Tee Serine acon vents 38 rs, Bett {paca thd Bains ey che crigin oF te 8.” ptyptoiy ad mnozony 22 Sandi phases ofthe eye deicion sr adon 3. “delinades and jai sovophye and esmetophite generation Al mRNA SOC Shunand 5. nomoler an terme _sletophoreris on pee <6. rawcipion nd tang ; feplitation a mutton 2. phentgpe a0 prt ioss and melas Solve the aloigs (mar cil, ‘Athypobaiea Botts has dhe eeneh— \e-5 ae eey* _ fe tmnt 1850 ba i 1038, How nan eel tno sa comi 35. Gig Ho on is hs DNA lenicons(! acronis 10" Argan) What te molezatr mao ee a Serge {600 dations) How many poiptres toms dots his DNA canon? i How many chaomasomet of ig (Ses crofo domestica Cr sgzigoan somaya) py aa moeeviar mass of aor 4 be found in (a) condbry Spematocye() 2 spat () 8 seeimuocye pak: nays) basa dips nuns of 2. TIBW any ei wionremlcbc main inc eles egos Uae en iets nara ryakiness) of a meogaspece (e)a pola d (f) mater bye se (oer: eeu (hep i oa ensospé ell G) ace of Eh of nntunetonal cli tae sho aD Soa gate eet, ACCDAACEY ANG TOCTARATCTA (0) wie sive nt cleaned fa 8) we bec stake mihin 3" a3 Renn ek ale PSC ae eset in ‘epeat(NA) how many uni wes le there be 2(€) Would you pet high-T ris ONAT Eos shy a {pianos reef: n Being of naling of we cars hots a sala nected vnen ee Ae dango) hall cons wa utensils we etal Chanpecenve soe oes 0 cle wits compe demitan ce A (bse claus 900 ae bse and 00 ve BENS Calne he vnber nivdons qi dunnny us) a nuelug(i)an = opt ‘ae ative. Abatis tbe quency of the ne, Metetwaygius ail weussive geneOBAFEML AWOLOWO UNIVERSITY, ILE- IFE, NIGERIA "PACULTY OF AGRICULTURE DEPARTMENT OF ANIMAL SCIENCE 2005/2006 RAIN SEMESTER EXAMINATION B AGRIC DEGREE, EXAMINATION ANS 202 INTRODUCTION TO AGRICULTURAL (GENETICS INSTRUCTION answer seston A,B, and Cin separate booklets) [itheve Waune pes 208 oniasso cere 8 toon e 3) (d). Synapses of homologous | No Suoapes ¢ NO: is © V ehiaseh carer to ne ‘ombinations | (e) Disjunction of pees noloccey (ander, “| homoiogous cémibination tas Fl snnce 6D , ae Ability of products to pe eee’ a Coane Unde o aes Gnoda devs Gb de B1cistN divide by meiosis ‘onctionrand:-significance-Fwmos, wcunrain Kaper oes y pa Db De 80 SHINE TH Supply the right answers: # Bivalents (tetrads)‘Haman being Garden Pea ‘ait fly House mouse Round worm Pigeon Cricket’ ‘Lily Fern 32 Boar constrictor i 3.2) How.many..amino o-acids epinprise.a protein whose MRNAvis 304. ‘bases lehgth 100% 3oq. (2) How long would an MRNA toding for a protein with 140 amino acids be?,Take into consideration the length of the promoter sequence Which is 10-and the termination codon which are both not ‘wansctibed 4. Cloning of organisms becaine reality with the production oft transgenic Tomatoes, canola, cotton aiid rice. In 1997 cloning of organiéins from adult cells became a reality with the birth of Dolly Under what circumstance and for what purpose (e.g, the SGMO’s mentioned above weré produced fi at purpose), is cloning acceptable in your opinion? SECTION B INSTRUCTION; ANSWER ALL (@) three pairs of genes R, Y,H for shape, colour, height of'seeds are known in a strange plant. A Trihybrid cross was carried out in the plants Using checker board method, carry out the matting and show mating and show the genotype and phenotype of the F; Fur = Wrinkled /Smooth _; Yiy = Yellow /gréen Hin = Tall /dwarf TYQe anvaten we atts gro. rats met ie | Pass, Udasined taco dofng PHNOM Caley sy ) eee ‘petween the following: RoR hae iS ee aFosin, (Quantitative and Quantitative traits fan . z Doesoipe Wine hs; somes ectett une | (ii) - Phenotype and Genotype [Pee nrg Ensim (ii) | “Gene and Allele. Gene \S Ine PHY dD Tonderoael Ghuret how gets ra ¢ Aevete [Lc cute (iv). Epistasis and Dominance | te Frm ofa Gent yang ¢. ee sree inves cache: invertor FOTOS open Te HASHES SECTION Cora Gume supvesses. He oF. Tg tnpea cutee, Geng GAAS)? ANSWER QUESTION AND SELECT ANY ONE BETWEEN 2A AND 2B Tee ey ‘Write short notes on the following:” @ i. Polygenes : (i) CC#CICR -5 mutant allele (ii) “Multiple “gene hypothesis S : (iv) » Maslance componerit (oj Heritability = & e genotype’ frequencies for individual. inthe population. (a) Dwwarfism in cattle is dug to;an autosomal ‘recessive gene. A large rancher Who raises his own miale arid fernale replacement animals discovers that, over srmumber of years, on the’ age there have: about 4 out of 100 calves bom that were dwarfs. (i) What is the frequency of the dwarf. gene in this herd (i) What proportion of the cattle in, the herd are heterozygous for this trait (ii) What proportion of all “ormal” cattle are carriers? (b) Inhumans, the typing of blood samples from 10,000 students gave : the following. information: > Type Frequency 0 4900 A 4125 ooat 34 B AB 5 250 + Caleulate the frequency of the three human blood type alleles from the data Shy