From Laboratory To Production Lsfi N\ Short Path Vacuum Distillation ete la ee eand Dame fit ca Seats Dahecres Pharmaceuticals Acid cleide: Terpone esters Natura and rhe a Sil le Talla Phas pony fie Eponpded cls beyanate| Coumeties Wen ty a Wer shel * = oth Introduction For the gentle separation of materials atthe lowest possible temperature, Short Path vacuum distillation isthe technique of choice. Short Path distillation techniques were intially developed to “break” the physical bacricr of atta below I mbar caused by the pressure drop of vapors flowing lisillation press toan external condenser, Use of an internal condenser, thereby shortening the path length of vaporsas they travel tothe conde a low 28 0.001 mbar possible even for large scale produc makes distillation pressures plants, Distillation at these presures results in process remperatutes significantly lower than those conventionally possible. For many organi materials, each order of magnitude 1 in pressure results in a 25 degree C lowering of boiling led film distribution of the feed for improved Combining this concept with a hheat transfer, short residence time and low product hold-up, results in the tltimate system forthe separation of heat sensitive materials, UIC offers a comprehensive service for Short Path distillation development, t CIS Most processes must be evaluated with laboratory or pilot plant systems to determine the optimum distillation parameters. This work is needed because very little information is available in the pressure and temperature ranges encountered with Short Path distillation, UIC offers contract testing capabilities in both the United States and Germany. Our Joliet, Illinois facility is equipped with KDL6/KDTS (glass and stainless steel) and two-stage KD10 and KD30 systems. (Our Alzenau-Hérstein, Germany facility hasa KDLS, KDLS with (CAD), and a two-stage KD10 system. Customers are encouraged ro participate in and witness the est work ar ether facility. Te fally realize che benefits of UIC Short Pah distillation systems, wwe offer more than just state-of-the-art technology. We can: + Make available our knowledge in the entite field of ‘vacuum technology and vacium process engineering + Advise you on all aspects of Shore Path distillation even after system commissioning and start up ‘Run test distillations in our laboratory facilities « Perform complete system engineering with you or your designated engineering/construction contractor + See to it that your service needs are promptly and effectively met ee NC Jolie ins 834-0869 USA Incr re 0542 Ct sccm WS ng Perce com Cop 1987 UIC ne