co sero mcerrmenesms sel ee een mace rn vr Feet nc, pet peppy ‘aang Y., Woodard V.K, Shon J. Mt sbrsieepertsion induces G-CSF Se ee teat Somat ‘oblast Devine Counc. 200820) carrrowi. BOALA CRONICA DE RINICHI 19: DEFINITE $1 STADIALIZARE al cri de rink (BCR) eto nine pied ex porn de aides € afecsprstee richie ponte emecina a rameret te etaoses, ‘hrc inden de elo, cea afer arm otal vl, cnt In Dlrdsoa progres poplar ines renal neil lb Suri el ee al deere RFG (apo. 6D mln 73m, erento Imeemsmclr alpine vennle sec dvie ov, deri gee {conn ran clan sale In are eral eli al font indy. Depradres inci rele die dn atest moment inexoab s pom jnge nfl In ise rena cronied tcril (RCT). La ba abr conspul de BCR st aca aesesiaea de prevonre aIRC, aa ineare se impuneioduees tpi! de peers ronald. Pe de aa pare, sa ‘Gorath BCR rei acre ie soot enn mores oases sardovsculr, sel ist Spree precoce BCR ae {Sepcsop x redoorn rs caravan sco pie BCR» ost dei de NKF-KDOO! (rion Key Foundation ~ Key Diss Ontsomes Quay Iiaive din SUA) cx 9 afctae renal porte (eet mat mare de 3 tet ia 0 redvcre persistent fe rma (RPG lin 73m de neem drat mat mare de 3k indent otto "Actresrnalt se pote ex epi tu antomopataoice evident 1 topical fe pn anon le ter fe de abr ange ois, Se pin amma imager. Ives psa era et oma invari, Inde doar in anomie ear, BCR exe cle mat mule et eid racic pom ose osu exaeul shim a win (et mai sven pen Preven) examen microscopic al Sediment ua (Ge exe, eure su sir) sep age (noma ecoaratie, ‘arf ets). Determine crete se estimates RFG pe ba eet slur de cxamerl ohm rin (eu jr tandlaor ware waco, set mete semble speifice in acl timp. simple,aimazive pun$80__NeFRovocie—ranncirn eoRETicestpmacrice cmtstre, mtve penta cae sant cle mai scum i ulate pene “deyisaren BCR la pence ur Estima RF we fae el mal eee pl formuls MDRD-, farce eters crenina se, els REG (min 75) = 186» retin fominn) «1210 (peas ar) Conform NKF-KDOQI, BCR se lai a5 wad abel) Aceh sire af la bash iden eh BCR exe 0 actine cu poem ropes ptsoanoe ex RPG ne S040 lini 3m a soe ‘Mtr fetal musi comiderte ea and BCR, dere in pene mu exit over prvi tenia de progres se IRCT a ase sep vasa 0282 (seal 192. enipemo.osie Protea BCR fo popula seer In dere ale omit ete stat x oxime ine 10% 9 20% (absee 3). Tn SUA, ste eidemiologee ‘ioale NHANES au tat © ere cu pape 50% «acs eae Ih sa 198-2004 (168%) fp de 1986-1994 111%, reales BCR se pimal mar fn ada a pe pci ou ise eset ‘De exemplyaalza dlr din side WOSCOPS CARE g LIPID (4 = 1937 ani) ident prezzja BCR la 23.6% inte bln cu ibe zara in ton, ACR a et depts 45,5 de cen un cca anaber (= 646), 341% ince el pig ch eto vacule cece stl haan fo sinh ge newoloie (n= 1.0%) gl din ce ou att ‘Sovsculre intra ian servis de cal) Proporta e pln moni pcisir ape rape pura exrl ‘2 dbl afte 10a i ele du dove. atl in merase eae aoa de dat sogerazt fp cb acasts elie se eglich rat alee in {rere ince nefopate tec yn lor atc rae (nefseees Ihpeemsivl neopati shemic). Spurl popu alate Yosh mat Sciatfn Romina atl nul patente tah in esi rid 9 ‘Secu de ln 424i 1901 $859 2010, fr sue or Ul pe ie Pence ren rent ml pec, Staite NHANES au arta ed prevale stile icpete md ale BCR (03) ee malt mat mare compart eu stale sans (3) bel 8) Ase as $e dren prokabil morals ste ete bainaike on BCR moda ‘oralinte abi in pwoap jamie din tar compliers fe evn, aot pce aun ts ede a dese eda shang a BRET. Rata moral In stad de BRCT et sal rida fel, ral de dees sa paint dat cu ra tne 289 34 dean est sir el al wet Pesos BCR in vt Ge 7-85 deh incon ctr alsmame a prevalent BCR, seas orate exces rca cose oe yale pir de sper mean ih, ue sn otemte (SUA, Cad Ausra unl [ar vesopene). Bie ems ina ens mages dean i No {Dorlas nc ipleenare nor poprane eal de epee ‘ecw OCT, er male ss prgme pr stse elle dh i eatare [End slr nen carr Se BRT net colar e ai, “Taba 1. Chars BCR Seder a REG 2 Ae rol ous ara REG 00 15 (om dl “Taba. Peale BCR in hes ae a sun NHANES 186200 7 fee onvriy Soi _Ommesbeernce) Tabet 3: Prva BCR sae 3-5. as re ea Nin a Gove Sere. cu “Taal 4, Pevalep pest BCR ASU. Raat oat Se Sea Shas Sati Sains So a a% 02% 02% Sunesseee ios im 808s[NEFROL OIE — PRINCI TEORETICESLPRACTICE 19.3. PROGRESIA BOLI CRONICE DE RINICHL pois multiple progrese Sree in mesic i $0.60 de ai In prevent nat retatvpfinetatamet efcete poy lle renal conceal Inet are pare din te ela inexorable BRCT, Oxo itl sere real ert scene re eins de 4 poet ca dict acto elope ‘Elana eiuen ela inard a tts Alea, net far lg erst inc tel eva BCR, ra progres nd ne arab inane 4 pig sincera Je numarl magne actonor ders Est Feate impor de cunt pesoce ace fst de iit pel pose ‘odin pea nin al degrade i 18341. Detnrea progres ol ernie de neh Cuaicres popes BCR presspaneparcrgre a lr ape: + Obj ce pin 3 va etnaive ale rate de are glamere (REG) eo pial de minim 3 ha + In cat pester nou dagnosicate cu BCR, 9 not deine REG ‘webu ola ram inert demas 2 spt, pa 2 ticle 9 oss nse red ou ever. ‘+ romesia BCR ext defini de oo xu deka REG > Seni 73a ip det ans > iy 3 ino + Rata de dein sfc eal bo nrc i, nf de pra ‘nial de fests rer cron de probate exo read de sabia reals devin acest inan vitor propa spelt De eas © fal dedctin a faci ele eS rami pe an exe mai poems 12 un pein iar cu RF ata de 30min StU ez un cin ete REG de 6 min, 75m 19212 Factor ders port progresa oll rnice deine In gee, se comets propria BCR ela deo par, de avin ‘tortor clo, far pe 6 aa pare dew sie de feta palogeniscomi, presum hipeesiuica Inrilomerlr, possi, acioen mele, alteares ‘Ssoveoln rarest. Pint prez is exit pin date eres stantiiee ‘aa de progresedntin sad af BCR i ait, Dap wicca Se trae dn std 3 seu de BCR ip wai exe de soni fe nat tec de Insta 2 nae 394 de BCR, conform eset Fram Far Sud, sone ae propre 0,3 % pes — 19.24. Fctride i nemedicbit D2 Factor pecs (seed stor gent par inftuenz spun iu ams, tole Fopsez, cob el a ogres BCR Ace tel ee Sn a a (ap. 19 Rana crm Ae rnc so inet de beri st arosinatiy un ft dn pace da traded ra eu BR fn pay tt ora fal herb ne ali de oct eu BER le ‘ex fl pics eal neopt abich saucharomerdapa pee) [pein In general oad sir de degrada inl renal. Sat nerimine FSH mute ge pimotismal imersdltie al gene enn de canvese Ingitersint id cel mat std sue cu geet deletede (DD) Peo at mare ise de frogs: Un alt xem erin pio ce plop E AporE), cre rin eseearicull de togener, pute ‘ool progrsa BCR. Astle prepa gene Apo ell se sitcom ve See eec de LDLcsesieol de tiie, np os prezet ll ApoE IV seasocua cu un vel eset de HDL set de iene 193212 Seed mae w nce oo sepia cess pest BCR, dat 5 uo progrese ma pi ete sl tral l aes indent de oa Suva 'Nise car dad eet fp se dtrearh acu or fst ets ‘ceowsclar grea supine fh de fone Sau isi ae wines iro ‘escola eect parca seal msc 193.213, Vita repens wm a Stor de ogre nites de mts ti reals pmare (glomeruli. Marian pk ‘See mng saa emia BCR sur pacen vst. Expl a pts rer ‘in rol de senses ronal cular ra a ni mame factor de pogresie (ex apt fctaren ronal a wise) O exci © reper ftpua diabetic seid cu abe rata ip so erepogresia ‘BGR se nlp a pen a ne 1932.4 Greate mila marr, considera inial fcr ise oa ptr !ecureneardiovnsclard fe aparia DZ. tp 2, dove a pedt ei sparing progress BCR Date ere ev ch premarin dtl de rere inraena se asociaz a aducu © mast peti eds, dzslrea boi’ rence RFC 193.22. Fctr de isc meio 195221 Proenza un fae de se mao, tue aco Apogee! BCR, nivel pri reprensind an pre precoe ‘Sse real et posi enema porn, cu et scl de pogenie ‘A BCR ex al mare: Pur mecaianle incon ruse) Rpeesprein ‘akin s_chemotineor inflamma eTacorlor de cee. 2. TOP ‘rdbtlint pin nj eller bale inert, ula lan inst erect insimeme, Starner) oie ul ‘Src awa rote fex complement LDL eid IGF, spec de Be Resp tle sell bul posal eves rin nara 2a eeepc ol mujor In endoito mezalina cui, Ace cep susa NFFROLOGHE -PRUNCIPU TEORETICE SL PRACTICE - ori ivll magni in poi celle tubule prima inersin in rerboia mutor pron (inchs protec curl iv espera Frolarea cellars ‘itmnelo iio) Megan (arid fae EDI Feesoron cfnezd ca eer pea albumin, sin, pact pins Ar leuare viaminelor toa meas tral sport llr Sean! caren ahaming, anterior dH. De mn tees ‘se fal eh epdctoraalbuniolor ee lt de eho de HMIG-Con ‘eluctt (atie) cre ines intertonen ite pone comple ‘meplin-cbiin. Aces fet inhib alsatlor pate 1 prevent pin ‘Svadinsere de mera foul de carvers HMG-COA), cul neffoxc al poteelorplsate Tate rine ied conovert, pl in prez pepunduse dna rte pice respon de etl {Uhulice Mat ptm contador nt dele reer I ral Sica ‘herokisor a cor ct nivel ules ee demon Diaue ecinnnce eaporale de afarensis prin, ainarea pronto sso complement Tail tal proximal teh Pcl froiatamate major. Diver oma complement ine fe ‘a alurinistuiret membrnarelomerlre, cen candace i spariin ‘peter de Ci formar complex de te CSb9 lal mia pecan tePsumubea de C3" cele tbulsipeovinal Ca une ho omplemenat In etoile ance cu pene copes 6 pent topic arte sec 193.222 Hipeesianes aerials (HT) poate represent tt 0 sa i a fx al bol rel, fin prevent ln peste 9s dn pace eu BCR O ce Inedtal a lor TA tree acl de Boal renal in sal pace fr ‘ote, Renate su RF es es ss Ti tc api cn FATA sever su malign. Oda cost fectre eal cone, HA reese un fice mjor de progres, raa ropes ind cu alt mal mare cu ct Hipereesrglomerr eit de write resin nse ioice su din eur divertor pata glomeruli pte rape omen en Fipenotaeonlr res" dupa oii ea peste sere Set ‘bil ewes glomerlrh ou vasoin rca tne ‘Shan reprerins seen dn cans pte plage hpeens Ingle Se reduc atl ein lamedare via roe meee Lec ode dice { Ceetees uel areal al cairo pomerlate oe pote conduc bs Tesi! alc de deradre coal eae pei un fa ech dap ai Ta aces ives tisubstanele cu ne roel are, prec TEM Finogenl sue complemen np toe de membrane bal omer, ‘nd secestate In spl utenti ‘+ Grerea peso littl mera aces pote sila prude ‘Stabe nlamatr,pecam TGF ets sa PDGF, gw expunge cap 19 ol cro inch sas Necwina pi ce HTA ot mpm owen YO ele at i i en ta at se Se ae sume) So omen oe cnc meal aM = 90 10 ml) ree cori el See rca etl se tT a a ae Cp oct cP seas re Fae ea lt Ee te wc lS Eero cola ean Tone nde tee ote ponte sec | Oat es ree eas pepe em some Bei ne i ache renee oe Se at a peg tise a teeta ea eS ce se acer pom Seer ee ns din, TO lian cn meg ce ne Pn mate eres, sis PA Letom es aE a tetas sins 104122. Conrol genie ev icin dina eine uo ona ‘ennai a ei em nh ern pind imac smear eicoicproaresa yeh 80 ssi alc Tose rn su sopra sn gene er iors nod coun >) popes a ogi pet eee eee tp ccurinipel 2 ex eaptola Nope dated > 19224, Aza mebolid eer compte even a BCR ja Rade epee corning tame ane ld rere alin te S02 inl pen me mcg dw comet yw a wees uit rele rete rn sate rac irl vin secre Tena eno nmin tnt neti oi eds crema es point pose tol Ge ich ace lek ‘Mate co sano valror tnt are Barba ada teeft ciraul de soi, dearese acest din uri pete stile been Ista de mini evs netavortle sa cabana neal ean 19322 Duspoia exe five ace Wl rea crn spi lax cesinn net nln a de stl ere aeons aoa si cpeinee ay cia ro pogo sear ncaa ipl etogreca merase os lr spd scevei pte sink cherie expel pe anal debra cea myc pisos ot ne Sc tic tance points cate inne de posers fe renal: In py satin pot action indepen fe ceen mela idl Paice! in ihe per mong a sei Fronflanaen. Ace dae ufo confi asi laze po seal Site no-abt rorss BCR find ma rap a ecu mea ee ecole LOLs ao B-pepod 124226 Hporicnia inpatient erat pops yer Bind considera de bu ete ng en ane lind feta treet noone sn st 9 ua Cur mae hee ee a Sd ri hipeersnea reals scl vnc cobra date sa saute cats, Det ane re tn mre alc ele ‘Ste ncaa exe le wine se, hein peas Bee ‘rn a en once pisces pt tui ene pte eer fscle neede din ae sen Taam ene Speci pci! pr i ven eeebenee sige i vue eee pg ssi esi release aia stone 193.227. Adoteronal pote combi regres boli eae pura sims {gesites spor mines, ace determin rea aca 9 ocd inital, Admnserea de anal at eceptnior mincslosace Ponte ofr gra de pretct ie ou sa dence spelen 193228 Retna de fai. Creer vl fost sei aa och in ile renee de afte renal Pe ined egatve pe metal oos, ‘een de fx coc de asemenes Ina pep a Progr bell roe 4 neh, Meena ptgenie icin a slr precip de foe sia in iri renal eu tse proinlamatrs ein isl soe ular. Tong pn in pratt nu exit de ce cre tet 9 eae suze a eet de fst supra Fanti renal, deh apices cla Sonor src orev o et erage ii us eal came, 193229, Grewaea corporal. pees sapeaponeal sau abe (IMC=2S 239 kan’ respect 230 ign) prev nc tte de ez pti i vr, reborn REG: Relais seve oral pace elses 19 trod de inh se onc eae ete nah sit a dabei 9 nbc, De asemenc, ‘sho suocie lat Ine inst mae corporie 2985 hpi tal de Dror alpaca su BCR sade 4 cies 5 Germinal es ces Fel fo demons al ih 1932210. Pama ee coset facade He ino in propia ol ‘ele aio pene Tamar BCR pein un ise de pn 3 a ‘rede singe nl tema a BCR dat St tal ADO nee Se Crverie ge plod Ie cn mal re cd sm tat cae ce Scthipencsive compari cs bie cu BCR acinar 198221. Drogure serene” de ipl hese sa hoops res Fc ‘en wns remit once de teva ori cnr sober in poplia ema caren conan pr 1932212 Nn acon Sn si rms BCR lie sand fos sin gal Se sabi rise nr relly insmplits i tsamenl medcanenioe Indie dca east eescu neil ee 19.2218 Cons rn de nsec nina les in combi) ie ‘oti ma sopra o cunt posts de BCR (netopatn ange, “epopesi aceon a dine eae nde de coli aes 1932214 Hperhomociinoia repesind un tar de ee diovascular ‘canscit Subs eu BCR rein velar crest ale hams src ‘haraie ew ini a secre real. Conform une date in et, INpetoniiseinemiarprern in factor de rae penn poesia hol wena 193.2218 rer anemone dt resend nei gay 4 sole bot rene roi Tot, roll det lanai nerds ne Fenaletmibe eons ams fore Teen + leva pal eric Se rows te uemie cic et foarte pun reset de ami rie: In shin, Theme cel cul ote adore a pcini uu aivel ai rest ‘tenn ter sugetind heft ame ete mit de impact Boi CV tira nich (esl, Protamenal anni bole cred der") 19322.16 spas mba conic ine wo 31 mgorne posi ii ‘al rich id wong sense ice spall de oxigen (0) 9 fred andl bj pce. ace coih Su-ri pone {Broa veccomticet inrwenle sat sur sacral cave aon il ‘Stevia. Lesa hence nunc mod est pera periul,ar Ftc es eco ea as lmaoS88_NEFROLOGIE-PRINciu TEORETICE Si PRACTICE inertial avofe tld). De amen piedte sapien gi bt ‘cere VEGF (sco de reper nasculreuilvind dap onset ereren cell ntl altracssgiogeeret Ini, sent care Tesune chemi svet we fee de edocs dest apt pera ‘emath de seldeten ps pogsa inulin renal Mail pela coc Ie cansei actiresRvobiter 9 vr igs decree Pt ince um eit energetic lel bre rene fctnd atl Rats Pitoconaiflor tubular, ceca e atrzcskspoptrs celle ntl. Tncomelui, meninres mice eae sani pi re impo mars prove prose! bl ene, 193.2217 tn ne, oie ced de azo & BCR (ex ep fone oa act) pot rasa prope ti rete rns. Et nce fd pace cu BCR peri u r aret aster Pte cule eevee 4: TEA supaput peste BCR eto hpstennen aria, desde ‘izes meet eae iret hemos arl sne uPtel ‘eos cx eran, INS) Dup eae pod ei Fal “Sie deregul an ail mre eier ener pes oe sae Inconel exist dover cle cae ats Lape hpererines aril, Sabu abut proteinuria eres wt 3 for mj ips ia posee BCR. Pe inal actin o imporana dose i pogeie su mvicuretle tefcisce zt roi, de atten sat-lamstoarte on-scene Bnd ‘le mai comune. De sce © oniorzare rcv fel really npn last ce vneoh o atl de oie i ce au rth Sa seule mai est 183.3. hlopatologapogrse bolt ernie deieh fn NCR, mecanismee adpave 9 compensator menjin 0 stare ase de Sintute pnd ae sesere» RFG cite 0-5 militar fn terete Fmeosatca comin pi a edueren RFG sb Sain. Epi acest at ‘erdt hy ioien oto ac are fended dinimeaea proses t uni de effete de o ere compensate travail pe witae ‘efor ee (erties) Modifica eminamich nil de a ive tno ream et repent de ereeren presi inragomerulare, cae deeming. hperolia ‘ome ein le epi cr, sen rset see a para ‘Acasts ier pein apne kiperfarca pan, deter eres resi bi in cai loner da er Vases redunerlssfnerizers transis psu aie src n> struc ear. Asoitea eer esa glomerular plate hpi ‘spl lemetulate (confor eas Lalas, tenes peal = peda dine "Eg pestane) ete esporsabl de inden parts pla, oes Soh ip 19 Boa rd drink 99 am rl eterinan in apr ere de leer 9 de inde a Himes. Aufl le asest nel po apron rat locate ca expanrce ‘ooseetivs 2 menianel vale slomerare 9 fomare de ses inte ghar ‘Solar fv pai apes Bowman In pl amie oso ede ‘Seu or produce enstazana castomer lsat In esc decane Sa prose iat Protsnle Se mas ier (LM, ling ein ale ‘Slemenul) rnin sechesote In sl subeptlldeterinind frmsea 4 eponte htne, cae cis lumen capa. Son sult) ele ‘merge vor pc ha mol ie exacellar cline rare {Poth facor EGE fe plate dere growth for PDGF @), ampiesnd Snes 9 dic In slr lomerlrs progres ‘Sema ansotsinzadeson (SRA) repecna wn medio important, ‘mosis hemonamice dea ve lomerr in BCR, cescind psu ingle, stun vsocnsicil predominate sive ale es. Pe lngd sun, sogiteinn Il ae 9 ae fet toremednanise pen cre ‘Seti Ts poreia BCR prea penesbt sete pameare Pot uci, rokfrare merangall stirs see’ de TOF. achaea mace $stnlaes producer de tone polamuo bogeee, eeu In ua oj prod de aldosorn,Uaoten medial eae itt SRAA (ECA, |ARA2)pemite proventen stop sau har reves progresel BCR {lingo In rors BCR i jos irra tbls, pt atc in pial lr arma’ de pseine ce poe determina ofc Fools Ta ive tur, cilielr sax poi ce poate res dit ‘Rossen pers vc early priulre Mente mote spel $store pepo adapta a resi ert ule 2 Dimimareo rotund ape in sail een (3) al BCR, erie Supt ‘et racine de demi eine tc de Iponaveni inves oredr apr hae pate Oe a esi + Dininuarosreaborpe de od erie mentinees exci esd at “edocs sta tate Ere aol sos (normal 0.51%) pote Finger Rese so tu bebe Te seer, eta jek dur pr ovtns un snd eStart ITA. Ace capaci de ape ose deniers deport exces dese + Gorse mri de potas a eal ta cote dsl a abu cole ‘pesaliomin BCR terminals pune chara at ets: + Gtr sree ate de ac pe ulate aries: + Dimimureareasorjel bute fs onrganic. Adaptile funsinale ale neni, ce permit menineea omenstze rpms in clad reich stone 4 RFG, af scowy” acs, ind {Stel atmo pte Se areata "compromial), concomiten to smut Tera ,compromisl susine fal bo adapare toi TCR poste conta cosets o staal, da an aserenen ma nel se poe0 _NEFROLOGIE PRINCI THORETICE St PRACTICE odie ects semi: Ce mlb xen de mgromis” ‘peel rere sce paathononu, esate ecpen,fci ‘Steer faa; ee dete a inp praia sends, ca Sone cnc eaiean mtsatke 194 FJOPATOLOGIA INDROMULUI UREMAIC ea acsreeratacnn cream meee pocetores Socetratere uae eles Seeeti e aatesaee eae cece Sto Soeuia rashes Sta eee eee See ae ornate cae ‘advers sh postd fi reprodis de adminisrarea acelei substan, si ameliorat prin ‘reducerea concentric. . aa eae poet eae Se ae eee ee ete a Se 18:12. Miperaiemi in boaa cron de ict Nocona penance cme so st ch ISUieo nl antes cee are Spe a ‘Sees oun mg ojo rr holes Gl Siw ss ep al sn as eo Finca ses cyoath sepa RNR eee ap 19 onl roi rite eo Prine nna hpricot x BCR su pl rset e pas nun clerance de enn th 20 lini 1 Milsons hpocaeic se dork sbult ea un paiet cu ‘Mlb nope baru su ati ners + Sidoatmestolt sve Giants dlrtiescoomizaente de pots, sioolactos Peon) bn ena conven angie, can Tree a degen bom sv anna sei. 19.9, Aida metabolic dn cdr ll rice eri Acidora metabo ete nu din deme eee ite i call BCR. ce most viru ado ee conta vel ctor eee ar nnpac eat a vel lind Beta sei de Pe ESS Sa in tons cone tapas: mead (Re Sees eal proper acimulres dea anurans (ex. POs”) EePuun acd sale ad pane se acd ate) detent © dora Se tre anonch esc rexpsbi. enor de ale semne ale i ata aroenemlbusih earn, inser eae sau ‘Sires tom msl ieee nana ale BCR aco, nial perch, devine ard eu gurl nec. Ferns striae rani out ers see ee ra boleh elasch ee cractrizt © mi cal de produce 6 exc a oll deans (Sie) scene dimimu ermietive a mast SERS intl: Aaa ape de tit ett ap gered a ec ce cetera pti compa pos J ence FASE Cte ancora st dept mae sider REG ab 20 i. 19.8 Tulburl de couglare dn bola rol eh “Tlbcre de coagua ecundare stint place conte important Treats 9 oraliaes pcenloe co BCR wrninls CRT, Moire reread de slangca mpl de singer su nies lic ream Ser rors guetta, gingiva, singe etna POE eer ou ner operat. Compile severe a pace din a eee vee rereentae de eeu hemor sat de hemo pleural Intapetaoesle ocr sw ee eee etre de coagule spa api ue! in id un rive soma saci eect defo aan al CoagulriAset ew as re rae Soe mumaraltonnclor exe pamal moi faci ‘ORG (romana) st picpla cae burr de coagule Tete mal impor odie ete sides ise neINCIITEORENCE $1, nba sd ee ei ape it ae Necansnl a sftp dali ean, dr spent are he ‘oe Tri nts fe weiss ca ‘ol sail in dere agregar, amor Gh Plt Soy soa epee BSc rs peel el i ced {insite atest decane Srekcnaer meet See iia te mn pcan open a mace a on se oT CR a oa ‘unui pacient fir BCR. Monrose nes ‘fo et tl igor oii ache ssh Sine wot Tn oat =a sneer soc ine tun de hnge ity pn tame ee tog rile Inbutstese Tusa pach jo eles ADP. teaser in) nave posucing Acasa wn eet reais ae Sp omnia fa cma rpc soe a at SerNee cape poem hoa apa eal tetanic pin cee nice ee Ila, itl f'n ok Sn ‘irate capa plea ie cen 1945, Marui dn bola ron ein 8 ot ropa mai men pet est mit soi ball cn 4 sii om ar Ts malnuiie uetich, male rtd sane Inacio In 208 Sct eral te Newey Mean al fc teen de protein waving” (mae pee cave ar ee sual emg ‘iam, Acct poe ete tit el ma Reever schol recat fico lege de Sse meutolc sex. Scdeen reser pee soe ocr xe nnd bie! care el et eadcas x aeneaay den ice u tal oni de inch sss mas! masala noe pa lj aaron step Cau a un cnanca a al ‘abel 6. Case espns de nia protec din BCR. ‘conic Rese iin aman e ep Groh fa ee cement Pes sng repent hoi, emerge wu mais savin repeat) nn ne “a1 Roa crn dei su rice deine 19.46 Tuber endocrine sso bol “urile eosin sce ol cnce de eh cing o vate de Sino so inch re en porta eau, id os see ‘ENuual in aero Hammon Also poy eosin, rena 9 ee ina. eo lh pr, ese, pep rats ial sinc asap incl para mene ee ‘Mestcwolte Si wei JHCR esc cu lb dese a ‘Bie mero ormea(2polein hore epee sa isl). ‘il pass Ts on ponte eka, co eee comer a Ts (witntaay cate snes acta nT he Pele wae de {ip hiding cn) cre deta GT Se recomend waren ‘Tstldncoua piss paseo BCR ou psi delish ‘Nivel rm dereyee pose fer pe eu BC sacl 5 cx unas clarmec sc oisirle e edbock polo piare {pita BCR pot ennai de ree ra cu daz eset de oro “Gece zu lint te compet a sie cu BCR de ea seit pete sinned stl a bss marie lie soa « ‘Pinal dr Hpolcemie foun, pace ce DZ sete mats a ‘Eigen neces dealin ft a peopel sane dh lepind ‘Sunil Sac snl neers sear oe cn ru ect ‘Eiipricnie yucca la ino essa» Neo dri. ‘Semche care impli mon axa sun Renee ace eu BCR, La hr vel plat ewe ces in ape in stil $a BCR 9 ee ‘posi de mua eres y cfs ete, Nn teocea ‘Se Star su nomad hr ginaitle met croc sigrind 9 duce ‘Sete Aceer unt Te de mires spemaogeezn impor ‘Sue ina isnot evens pce aise pou ots mpm tubretr setae, pelosi nu aca. Ta fence ev BCR staf ae hese itr ne xc tipo gin-ovatan Dep inl. IHC Gron una) ee orl Is eae Sc pol ee, id i ea were Necul stat sponte! sonic Ia rez rai in Pets paemtlrc0 BCR 19.47. Anemia incdr bl roi deh “Anemia ce un din cle al impart complcai ale BCR. Acasa contibie ‘Seiler ev pri BC, {THGEPO sau coitna pace donot numeonse ans eng, Sind tel exp a acl eons pater ve nacre rivetsa__NeFRoLoarE—reivcwu tEORENIce st PRACTICE une econ fn ai 1980 a schimbt acs sue Shera tamer ‘emi are manera ale conse bees pean nce str debe ‘nein coal bai crane de ich exe se aero sinemostr nil de pil nia seen ped ea cops $i seurares dust de vss a bematiler Ami Icepe spr ata cy ste Sera de renin sb 0 min Stopes pace abet ‘Conftenrecmaniler KIDOQL shares snob sham a pce ‘BCR tebe eas vr ale eran! sub 13 (12) sabre (ome). Fra atament heer penton cu Bols cron esinh ana $e stblizenr in ju val de 2% in ne singer stu maiz Diop nami de cuz Yrla se pane pein exlaeren aor au a wy pacinteurat dear homer sedeas Eales compe tebe st nla Inst evvocar, suma de recliner fin, male oh abs tromiboce esl hemor. Avent etal tifa ine ‘eine ttamenl ev erieopoitna (poeta sau dasha). Frnt cre conic la apa stem in ala roi ech st morale rept scrtarea due e vs Reuty deiil de vem, medi wemidfcin! de ersopietnn, ceil eer lanai ri. Ne ‘ist cast p dpi ont aceo factor instal ip le ol ‘Sence dich Pic cu hol ron de iih au un ne mare de singed secur iinet ombocinre Pri cach peter once repent rod, dina au ef abot deft. Paseat in hemos pou pede Ine game de fe ean. ed or pied sonia 1-2 mg, desk splemres fr a acai capri de ase ee owe ioral, ‘Se osetia pci aa data de isha ete mal suet uo eine fi de ora ‘Se psipune ck deft amine a nei anemia din BCR, haa inh iii de conto Pale daly se ecomand spleteeitamine. ‘hens dover ae le ta teeta major “Teena de mdse feats nostra de exes miele ‘uot ptolope abate bl conic deri Insti “in sige, ‘ost oot tue ci eur de cll din ans bestpectc fhe ‘ap expuneren Tn sel pce cu BCR Stale in vv” tu is terme snegio wer” in inareres de 9 expla corres dine prevelant! Sail BCR. Un earance sab 60 mimi a fost wot a nel st on 0 real a ans dep la 75%. Ma mul pada a oserva © freee Hatori oath eu ceren feeens enor de hema, Poti contains asc ndpitaes "med uric ssc ae, Defic de ertropocing ese ce lipo cars sane din BCR ‘otc ore bi eae celle pert pilates eevee sz rela x gra pom, Catal ae def lat de ‘topo au ft stp Spin hate [htooitin ese pod a niell esata dn creel el ice acini Pi a Se ea ses, eee an Seat tle cgne near at ce tnt BeartiotisietesetacscntinkS a ra rns chef aspen SEE ren, Git cin efgels ita ss sei ittennctmtakina ea en sci he ek aor ere cmatnes In veins ole eit ig Conn ein “oe cps ic et is vc cor fis le de rraiin afr onl ne ape BER cau pinipls 2 annie eae o rere defi! de fer. Piaete Sh at aor mca oa vel doo) vectra din sc nn eee lp! de hemoghins Su sos Ce eH age care atu sem oie Fel ee {GH cast uve cr tafe pt ie Caspr ak recP aba la veh desc etl cers di ace. Aces fel er ut a se co BCR. Dn me Ie asus ss$96 __Nernococie —pravcia TEORETICE st PRACTICE malo) nivel see a waar ee a jute de aloe nama, ‘siendcapecaca de toot fo Desumenea, cout cee ‘irc deca fr tl shana seadcrc satura nse 9 eelresfrtine!.Supepues pedir de et (scutate rein alleare Sorc drut rua in ems combu Indiminuea emnifeatva s reopoiis ace define pd cot das Pin ans de splined er lnc ih ec ect un sta anspor Nivel ested cokne pro-ifanator,uan af ean tsa oe "puss a tant ew EPO Ia aii cu BCR ermal, Chek pr inforaci infueaca prodecta mune! hematite mois Semne ‘msabolisnl full Do rane rin cae nanaia nein anemia ‘ln cron dering su pe dep ciate, ft Gece val mele arpa an linge Hepes ppd scr de ea eb abs ‘fi, irre ans dn macros mse prin ncn aie “Meical tebe se pnd i termi ald Gin omen era de fear lamer Sade ub 60 nin 73m Install NHANES, gel snc (b-121 pl. — br fend) fn sad a BOR at de Se Stil 4 81% prem ato pace sta CR. Rasa sa ‘ie ite a orevaen at mst ile BCR “abel 8 Renters sr dn BCR See ee Schderes heen candace Cre i pee Regen ert ings Sibir sl von ing an oe mai de nf ie ‘ron ae ot ‘she idee 194.8 tlburdile metabotsmatl oo dn bole roi eich (ac dell useage odor poesia ames ner, ‘tment sere sla se Tots cc pec 9-2 nicl se ae boon sein mela foo rina Cop 19 onl cro ikht (er, 25ers) te de coe Bai G2, Seep de cep Tenge Sal 3 BCR cyan ihr ba ec erence se cane ati i es oi ie FO ‘Phelan srr fs eds comets 2 tdi {ops nid Guna uns oot n= cet pciewe cep PI ve in Sc skal pa eee rgd awe nih ce PTH « tect it aa Sie fag ec cafe ree TOPE. Rawn e sone vse Mama ex dine ee tes ns sor le en vinnie, fof ss le tne PTH Ire eee seve noma chime Homenlran fondest cote a ruil enn nt prof ater ee sc Sond wn apa afr ups ee nae teria Some Sor ac oc sb ape na prec OCR ee ei ata 9D, arian nse 3 ale BC an : \ \ CS Fie. nude eon pei cnt eet wan de tii rmal sa pertain secon cea ye male eens cee Boss m0 ‘Satter stun ct Ca mash inerspnae a ines emer de ‘ison ine arane sca al cron de Pic CTMOBCR). Aes eho8__Netrooote cia teowenice sl pRacrie ovespunie mai cirnd ui sindrom, det une bl, cre deer aocees de ‘oma iohinise i homonale, mols paste ale sc eos Sabet extacbelaice, ete conind nets tcl de mete ‘aniovasclr eft s de morale lpia BCR (ver fg 3) ‘Conporensle TMO-BCR sunt anomie Nochimie {el ot PT, ale ‘mela amine! Dy noni cel one alice eset so epee. \ Caleta \ oe igus 3. Tahu meal nc oso sca BCR Anomalie ochince sf a nvelaie sore se cl, us, portman, mote meine Th Cae ee Pree neo i “oma cht oot ere a araover, miner, vlan cere lina le na, Din pnt de veer ne, eu al nvr corse (ad) scotr ronal exe facun coat. sis cu roe scien de ‘alia, ir dlr shel nes irra cor ep pe Se ‘Beene aac berate Temenl decode el reframe oxasein BH ae at daze cuneate, pn pee ons, Csesdneoa remain ste estas haspalpe fr pry ce nd Foran ver ous Ge nor ee) oe {St smal volun on eds, tonal sv erae pepsin sen at arene coe orcs mince somal — ~~ + Ot irons — mover res mina noma + Bos ota anal — rover scat volumes st 1 Boaianih-umer sot ies noc Coleone exalts da ale aor jet fom adse ae stable obra cre a svi eel vase ‘Shlcnte par fee. meade. (omograte. compris, esesrale) at ‘Steevie secs (creten peso els pls) cu moras Tonle de cur arlovssla Ele pr cu at maior cu fit {toe enon tatiana pt espn exces de molt aioe Semomat in BCR. “lfiaie ee esci cu dest de cals fsfor In vale atrial sua, doindprogisy necror acca pei a fest dion Se ‘Sante il pn al dr sa lel in 200 pea dep de In ‘ra 9: poe lan, cope, pete abot pet. lian oni Tit Inet ivan (comes chester el Fosfor 9 os ‘Mini saps oem dos 04) Motiesile casi Wochimize ale Roi cae renale sant repent de hipersitemie, Ipcaleeniemscne vet cescue de PTH. AGC ‘mosis ap inet dia sade precce ale BCR, Pecsind o mnie niet sees prune Asi onfr all ghia KDIGO (Kidney Dise:Impoing lal Outcomes se coma montreal sri ‘ih, ofl PT Satie fxs seal epg cu HR sad 3, {SN opi mmieianesisepe is BCR sail 2, Ola eu protein BCR, se Imiemiieh eevens montana aceor pan. de magiies ‘iain eats rose BCR (ve tbl), “Taba 7 Freven monitors Ca, Pp Pia eng de taal BCR yepsts SESS Explore imsisie st lone pont idence cliaren anomie tender pain inte persdecori, Pte ae infra ine aa Xena peptic rpumel ls tame medareios gt ‘Sure moreno chrugale Sort eiteva metode a-nvazve feats {mtr pst cma ltsonopmai CT, RMN seintiai Unomeaa eae lsh laren glans aoe. Ete 9 met none inva pute eve evens pul pete partie. Sao ‘Blue adlanop ep epi, el mal coun ete Tenseson [NEEROLOGIE PRINCI TEORENICE SLPRACTICE ‘cease eid bio pny locales prechiruicla pratiidlor in ‘pepsraoidl seca Aro Sesliae csc eid ses ela gu glint I pace cv snes persed (SHPT). Expo ‘RU CT pt wire ds lolz oral parse Tn gnc exminaes aloe duce neared oa oons rea zones ile pusogice sum nespeiee spar teu i cus bal Demincolicaea wos tae i edule sve penne pte dca Falinoge Cele ma comune modifekt radologce in SHPT stat covunie ‘Spel creep pa dats flings mci. Ake oer amine pees {ros superosble tnt exwemta proximal a tle, colo eu Ferman eters dl ras ane prime alli De scneen explores alos pute ade infra despre clieale ‘niall Aah in sale 3 de nectar eae econ fete uel ‘agra abd pol eae pote Htlizat per detec peer ‘ce eater sae ca keratin eznabla poy CT. psi ovens. veperin coda gold anand pera deterinares ‘wor mover eas. Aces procedure Isuarea maser lnenverl cua at de frmae ome Ix arr ste ale Suc, Fem reser enone, Bip ose ese recom earl actrloe Foolish, « hperaleeiet mua ipfosterse nex, azul ‘apes nonce lumii! tn epi tier. 19.4.9, Moi crovsclaren bola rons eine Bole erioasulare (HCV) repent principal cue de moral apie (SL BCIe Acca eatpe de prise carter nu oa pao eae Ia fsoror dense tate poo BCV, pion exponen exces 1 fic eis elo neomentiral, le de w= Rata de root 8 ‘enim caaasclre Igor (posi infact de mora san agin Inoubl ener ptr, nba pacer dala carpi de 1% pe tr ucmencs pace! pesto toni la Sa de nd Ie DM aural ‘ilor despite et asi lie US Reval Dea Syn Is 1 Snpaient 184.91, Hperofe venrclr stg super carat CGromioptin wee, alc de hola cada chemin, repress cole mai npn do Se densi earn apace eal. find xe fn de sean tri a mon Ge cava crac Prscin manistare 8 ‘mp! remic epee poo veil stings (VS), Tipe velar snp exe 9 motifeare apa cae ape spuns Inspec, de peste et de vol vencl tng Pi a un unt moire adap fc arora sues dec miler rina defi cone enrgct L aor conti deren densi caplarlt Iowans scdeen rere crore 9a prc subendocrie igre. sec anes ect ic lpia Sr sad Caan ecu nosis oe mae 9 ecole ti Ct Cri ons im ie i psi ene eon et lope tet ga irre daca la caropai nin vera tS esa se roe VS oan ea ml “Taba &Mecaisme de supe VS. eo ‘Cie vit oct ee tcc SE a ee ein alo Shen oe ‘Et pro concen Se moe exe sng tnt nese Sean oe emya wee, pene ra se ite etl at rh» epi carb peat OS Fes alent pve pesee coal benny 8 eit ‘hl ei fer i Bn srt nt nes mie a a Ea ret aps) orate acne eel at Te meen pone sole, et ome aca SES Tome dna ea «ren pl, Does ect Se ea normale majo pce ah em Soe veal ee eral sono a dnt sets cloaca ata pes sans vpn he os ae oot wnat sine ek es aan a at empat DCR iv Ss Se ym ces al ene born rinaredone pace cu BC, ese eae de ws nia, sexa msc, chensecnnic eeolmine atta I aldestten sum te de eer ‘Un at factor carorIa_genera HVS pote reprerett de Ftc valvlve dade: Majoras Yeo value nae ace i BCR ‘nt resect de clic de nlc nsec! anv! valor mild ‘aoc. Prvalej clecnor aoe In poplaia pinion dala exe de Sot Stenaa aoe ose vlan vp 6 fc ac ea pert ‘etic sting. Vista, dara dia hipersteia pods CaP scat ‘ent nia ats de ise In slo aoc. Calle ale ou ut Je fect ii astride ise ma sun at Ge ie defi Clef aurea fost de asec apie cur de rit de conde, wut els fav ctitcte versie perlite Fc sta 0 morals cee sat ‘evertaecllic eguiaea mil suena verre sting. Pain hemody eu HVS po cla gun grad de dunce dasa. ‘oaths rigs perce VS, reser minors In volamol exer do I ‘rer somite ale resin To VS, de mule ot mana pie eer Iiptesne sinpomati 5 insta eum rgb line Rent © out dtunetie ste Distincin slick ee init mai event Ia pacino antecedent cexduvasclare dinates nus Io dalok Aposinath 18% din padeah a ‘Eskimo moment ne dec Net, hperofa san dlaares VS vor dice Ie cadionopte dais “Tubal eli et pc acne cards decumpersate, Edel pln et poste en drop ue ie diafnai ssl seed adoro! dls, Fe dafunia dll soca ipl VS, 19.492, Ateroseroza yorteroesleroxe Meal aren, impreun cx modftae mebolie 9 omodanie, orzarh Imei de tip sersletc a nivel atersor crear, Peles carat Istemice savas in more ran im eilin Tore 5 975%. Dinte see len aprenimay Sinopec dab sul sapomats ‘At factor moral sig meni cob Tafomares pci deseo, Hipertensunea sri Sau cage ule ifs aslr dela scare ‘ine endl ace mecanim ve ads lp ctor de ric pens sl ‘eros (ez abel 9) ings fcc devine neotadionall menjonim inflam yi aie ‘asta Stile cline u demonstrat sh vel prosins C renee (PCR) ee npr puume al morals ait in hemodaia et diapers (D8) seve en pesictor independent l muri de ple esto sa ie Iniarnede (ino media eines”) Ta vel efeelt,fn HD et in DP Stile epimilgice main rl PCR ca ce e ie crx re pobin ue posi ern rpesce usp sa reves. exinea morte pid to space HER ee pote eee Lae nu aa mar cme caine Io SESE Sele tar rc pom tele lor cade corte SSR'AID dan byron sca , ptomeitens @ Ss Etim, ey in pops geno entice sun prior ey ‘Wt ins pope set pu pase ie Cates pre to Sera wn me anemone a Gt ria ct (nr dete pr HVS), i n edict Smelt oes pc eos ee esi Shel dn nai se eur spe ssn cu dpe iin a ‘ell shine noe). “Taal 9, Paste aaa in BCR ore ee eT Bote pant Nino ovo de i poses Metts toe dee Meee tt sie comps an de fmt cos Teter cial — ‘ate name Hipemaa VS Dalene Newpazs steed a vel ini! ut psc vs iin se ee sina Seesaw ede sina sr mc in Sesto, ae ta ae Fae maton on Donel ae ul mtn ten denon sto, pn far de onscribe,p akers se yee tn poet sisal, endnote ce ere Stoo sc 25% din pce cu manifest icemie ma senor coroae so ei ed pcb cpomsloga ene sense See scwslwioar Lap! cv VS sep 0 omerie COU oar les cl i erence volun he clr ESE nl ane lh cle ser ios [NEFROL Oi —PRINCIPU TEORETICES1 PRACTICE 194.93, sei codoceymeertee sub pee yen sighs srnaan sr uc uu Hs eset Simi cc pow cir crc > Ce “Tei vo mu tl ulopse sn esac din ae gel SS). Asi utes home Su su FoR po ci di: Moneranes Hol dvs lt Sern semis (Exrc politcal, capt, TV nessa) ie apr 30% dn pe {Salou Petal sri cps stripe evn Hipemra VS, al cack estsen ss ramen ig Tramet {Sh cu gus pace fos burl der, spec posite nd ‘Sartplsne poem els Sve ure Wace ae Hipacaines weil Gla poe 4 Fun er pcp llr senate irmade lich, momtasa pr a inns “pn for Tn ities panel war prs ca mec apart er. er rubnnknd ersiolse at vole Acne met ales wa itor ae anni sardine, Aco sun ma ecole de va alcatel ipo VS ‘Sarin Span eae al ean ni ee, ei unde pt deine pte rae Sbi ee Moan sibi rein un des in psn de ea deal sing ta am pu fit ptoogie amenttowe de vik La pie alia are © Proven 710000 gee de HD xem event avr abet mo Wyck cn eater senor cent. Aproimat 80% din_morile sabia ‘rie sant consti bis sence a eas popula geeral ‘Slop econ ns ete prio cazt de moar subi pace ili tera de ip ice! eras cu satin a epee ornare ap ‘cl de moar su In eoptogenia mori ute Tape daz su Fpl’ ipervota ently singk Haulers cao hpevlemi, Iroc sapde ale slo hiereacttea spat Spe Incr QT, Sasol pons su aes metab falc 1955. MANIFESTARICLINICE Manifest cnc le bli rie res dpa e radu sini ree Promenade al pci hima ch = 8 pan inom ace @ alee ‘Remene pcen por fini sine! sind le ete expat ed0 pane ‘Aisne din fins lor reapers, fr mares ndesouye, Ennis 9 dsiminars Sor pack sd respecte mola pes put f unetro srcnk exe de dill, Pace x lexus cmon ce [conn has fom, sim ar ADPKD, su a compli new eg, rats pgs a op. 19- Bence rink ett ee i necstts nuove pate dior ‘mir Berta owt roi == =1— gra 4. Nexans af cies in BER rumerse can de ba el conic int gest in sie eS esicing nem: dabei, carla, ole oe, doa freeones us el ie inomonea relay pil pie su Sago, devas6 [NEFROLOGIE PRINCI TEORENICE SL PRACTICE pero c sinptome neni oli eal cove. cum a fasten ie, Sonos aortiy afc excepia acl mat avarat BCR Sings te barns pe supine lied. conn tein pes ‘een yr. Laexrom sce eaten de pach seal ot care se Previn tual rele au, ee reves fren de urgent aie sting aposimatv 9 apie care ing In programa e spec Femi iil 25% se fl ntl paid Nl ral tan nd fe acest neilopu, eco dl In url 3 Tun de In pina fees Ina poste 6 ill de eat ieee insistent eral se CR, inxt"o amunnerh deli, camend! Tas coc complet 3 invesiile Prclne adc consti hia gosto (er abe 10. “Tala 1. ete pear al coi "Nisa st de site ml es pease vce, pti signs rs nl dt sana ae Palo, pees pri enn de afcae visa snipes don posse ol i Sra uma de mbooe estat Stam emocent chil enact: dh hat. ile, ‘walpaper cer dare tin cg) “abl lineal BCR tn sale 13 (purl instal 4) ete dominate sence smplomele ol real aussie cate Jeti afectaen ala “honk Clin dapostol seme rerle steve soit ev BCR exe ‘tain in te capil le cesar mana Od Gu edeeen RFG <30 min se Iles ncene ano able rae especie se BCR. Este posla ‘talus snore in pal file, Dt manifest ine plas nos fi axena progres sant fEsomene ela preci n sal 4 a! BCR. fe cet ali aaron iors erat) et orem de eset, lp reverie manftr cace gnc le snout ae. note sie TA iui renovsclar su Tom pancho poe dtermipe Seng {esis bo pean seer” Ode redhceren REG 15 mini den ‘Siete nites lie plies sider emi em jos Paci ox BRCT. Proporta pinoy BCR coe prin x wend sromied ma depict 5 poco eps of cont pot declan ze ernie sau po pearance. Tepmentle ot peer ears oi rar iene, rrp, osu ceicunnare Tere Presunes aed ete come inl sh se ce em site S ‘ct depletes poste Haul ok pera. Seyi. ue Sept a beri plmorre deme erate - i ese invcianie bochinnce a dena o cnseale «oe Pa aga ein sence ese 12 maa Roce, pero, FEI estos meuboich poral compet, Ene pte stems noscrons fresco nnmaeale ltllor ae trmbectee. nada saves pect peri ¢ anamnezh din, oar antl rn eet a agence ce 6 hn er, mats prin ‘Be oro: pig ya De elem mo ales de rere 6 ‘ers Teun nee sl moti! de amie a printer nile cu wt avin de ante macau sence ip de rents medal rea at Peel dnctecen paleo 2 side sn fe ca ewes a cm cath Masbate ac stor ace ese, cle aerate dept mc ep err cores HDS subcee Span rene a. sot ean nce Ue pose ues ures impish fects ita sect senor (er lsh 19 figure 1) Ie od eae a ee mesh oan sue id ade ire glomeruli seetn pr 73 mi Tough an ace npr st como ‘Scie sun scalp ent era ma pres ale ronce (See ecemp unc RFS sad 13 bin or 73) “abel, Mfr pce ei “GENERALE seni, be ‘yet ‘eos ee tac nb _soniiesneae ela innon bia Tombs reeled “i rr ob ie at(as__NEFROLOGIE -PRINCIPH TEORETICE $1 PRACTICE _ Tin eae wT pou ra dase sl re evalane pend. Stunt finice care imp ern de arena piel nef ecea i crept est grvaen bol su chiar ev sre dee, in {isto nti pomple tant de pci wea: 2 Sgeea ereine seer cu OSmp au tere procera retin Stew cn mt 30 (1S) a de vale anita 4+ REG esta sub ISmnin 3a, dre de aacerer maniestior 4+ FG estat te 15-29mlinie,73, daca BCR mw exe unos sau RPG ms ‘eas FATA mag su ersten tame: tubal ech ie lel aie, prtalcnie =P, Fipalaliomie mt ipercaleae >I ‘eon sec <1 SMEG: In depisares pene pote 0522, a ematrel mioscopie persteate Cheval ute nes «incre usitae tte! bl ssice oft real (esl, ps Get sie) ance dicondas eu sta BCR sau anemic sever gt fesegsacdoset meshaice su anomalor partie metabo fesvcalie seh ogress REG sy cota popes erent wn ol Insta BCR 3060 ain 7) 19,62. Yatamentl prose fn toate sale BCR ese its depsurca frie fiver a proses (Celt fon fea ate inet dup stencil Foals mbes acre Ace i. fot eta suteaprot 18.3.2 Mitra ela resi ae te oigstore eae tail BCR Morir psec tee eect pti, aisle diferente {eel BR (cel pn anal aims ous ti a es pr ez REG Onlin Pu) ebule s i 2 Geameo sdiment wir 2 vei apie eal: 1 la esos adobe (Na K, CRA) Monitrzar practic mai frcvet et, de asemenc, nesta oli reduces RPG eu sim pu a, impreza Tarr des pent progresie ‘cotinine de eqpnee favo de rie pons ete oun RF su cd Shor apie toe erp de nena pores bl real, ‘Saya de ple scar in BCR ete ara pe iterveni mil ae sorte lone trap ei conta aco dei Inger bale ‘Sul crn piezo cu tani deduce 3 REG ce Sani ‘SUT init eat tcenien ayaa de progesc pote aven ene ‘Shift de eemp sire rial de tn nto eral ea rint pr Sin pa ote nei cuca Sa ie l= Pringle mis de insetnve « progres BCR, in inte de sve doves sn reat abel 1. “abel 1, Mass deinen «pro BCR vide 3 men ie epi ase ABA 6. Comll apa gi Sona SRAA GEA ARA I) 5 Tamers sas614 NEFROLOGIE PRINCI THORETICE St PRACTICE 186341, Resa protien pink ple nerve ropuse pets & ‘tein von Ge popes asset ele sie Us mare sa ule, ‘ontmizt Mediienion of Dstt Renal Discs (MDRD) » wt laren [Slit probleme. Sa conclziona cg reduce 4 apr & prone cu 02 ‘Shel Conde la seldsen at! de ein RFG x 15 vl (oc 29%), ‘Slacrewee ute aril de rpesvete ‘Dovel spon in rent mu fe susie puted a state de resi pteie ca tame fac io tpn pope lca mae Former de toll volt roi, Tot 0 ei cu reste prota model trie consider copare cmpoot pln tapes, ae pei apna thor compliaitaolic, cm ar falda, pelea, pees 3 Spomete de uremie. So trcrmnd un port tic de posit 08 pKa pene wie infu prasiouoe y HR, cxeptnd we de alae 16:32 Restrtiaeportulus de sr I 80-120 mala (arxinatv 238 NAC) ‘xe coum coool dea opie aot al TECA, BRA ocurred eal oadiropiinic. 18623, Analiza ends nor ble ac insta) MDRD, cv REG tite 2eSSnmin ns metanacrvinne! sence 19 mpd a evel 0 asc Seaman te apart Uehidlon creat prozresa mai rapid bli rena. Rats de decl iasipamerar a fost cul min pe 29 al mare tatnoi cw diect peste 288 Tin, compart uct eu Geet sob 2 Ti Coe uni ute sogerenc apr exagrst debe pote 8 et) mu ‘ein tomar ean olor su BCR, males eo poise rea. 496.24. Mecinisncl prin care fametul poste cxace njria rea ie perros dani tlh scemare barre, Ny eta ina sta rope caso deme ent sevjll aap sap cel Fre Tost bocamoniae ete psn se scot sur peer bale ‘ove 4 pumonae De aces, (pace cu BCR tebule re muna Su ners atl, dr ost peta ine aces sx, 18635. Misr omecolpe de neroprotei ei samen epcinas, omelet stra, cn gem le dabei, crea ian metabolic ‘apa hie aie Terapia aniprotsinria loses smal renin ~anitennd —ldosoron alin «inhibin al nin! de converse wangoensinel TECA) fee semniie Amiprcnrce (ola pocnua cu 388% la popula non-diabetic) Muletimaeis sions, aiatce sural, dtm reducren atid ogee pe BCR terminal carina 30% «+ boca rcepraat ATT ef angltesine! H (ARAD)~ a vail ea os ‘Ane is eels cman ssa ec vada, ania Maree pir smulrss copier ATX Pec oper fixe Alors apt pct cv dabet ara up I snopes, (hr fn ce cu runic pens Lasrana sara rer 18304 progres BCR Te acest pte Ustanes TECA AIAG seal tc eter hemo mediate 3 Fant eal Ace ia 88 minor (Snr 10% die pci dea ines ‘onl ca sev ae cea oie ssi eda 5 ‘Gr Cr jo pacer uni tema se suber wa ch tetova dup fan de test), Tota. a tie sas crepe lo ECA To yon cs SAR speciosa alone sie ‘Seesmic ores 9 ep Goa aia ler + combina IECA = ARAD nu dove supe next epee ‘Sonnicunsren fend eiponri ete mperr ltd masts inne srr Mat ma eu de pers hte ural ores «+ amugenil otros ipronolactna $f eperenona) ceo sipinets naa cn an a ats GuTPCAARAZ. oc gone iva arn ¥ spimentr eri uy fect rodent aries ‘hag Stee pctv ape ogre BCR nus pe clin late + Inhibit rc de rnin Asren) determi occ si 8 Sev rene plane, sonsecath a nivel de Ang i loser Tote pcm gl ensneh areal dmunsete I ooeserapie sat In «+ shamine D ete analglacevea aoc amen cu IECAYARA2 nermind edocs split potmarl, ree Ia inl, ‘Gru tnerale a infmaties le lomerre s bulitesi: ‘Ste fete su inp de initaresstonfa ei — anglers “ower, Dey pomiaiowre, asst fst reoprteveUetuie cota In Stal rundomit were loon oe ele nowdiivpiidct redye_ semis prosnai independ devaloefnionale; po 8 tig a reopen tame (SIECAARAD ni ese oer su prt fc pte ona. ‘Splines su icrbona luce progrsin CKD (Set seal aco progres a BCR). Ale mt isan TF es et: nema rao wn mnie 4+ HEP Re ofc rr propese BC aman aaa fra mor ‘Gan tte nn eer om615 ___NEFROLOGIE-PaINcIPH THORETICESLPRACTICE_ ede a ama yi Sina ir ro mr rei ome + Refine wale vee yw mre eT al aed fac ‘atmo es rata en pi MPT + in le met wi tom seca Phra id rs rr eprops CD re fctcperenh dae omen, “Terapia ahipertesi [itv comeiat alc de tin, un detemiont major at poses 1c prec sal ei mse ces ola nile cd TA (Ste ian eh nefopat sci pefoserna ara cases “Spandnaghp levorizarl props oll ele Tt valle rset ale ‘pri arttale sierace nd hypertnsune gle fist contac [Etpecantsml pope a BCR te agravarea prota. "Vale et eons Sa ‘bib 13080 malate pore ub I; Nb 12873 mt apace ev ibe tar sau proce Ia Madi de love oe opeserath de oars sstemull RAA (bio a ‘ovine de sonnet sani receptor J egies I) vez a ‘Control ice a dabei Thora murals neopatedabetce pose fact de medi a hiperens yd conto ret al meablamulpoii. “Con slime ste seat a pri lta protein line masta 9c wines ade eteere 4 ereatione Tose eu dake ‘Dhara p I pale cu dat shart sep am sun iy resi sie oo cridenit reduces teat de propeste 8 nefoptie, de I ncn asta pres “Terapia bipotipemianth cu tating Tipctipemia anes progress nefopatlr ide experimental Mecania resis cn leat de same de popes cu deste mis opotne tite le nivel mcangul tpt ob doe i ehintres ct 9 ei ‘Cosa fveriend ple slr expen zai €u apn ‘lmernlrore "Trp fara hiplipemins webu na cn cence sik & tDt-colstel depgete tog ar obicivel tame ete meni tui vel de LDL = 1p Dy lel vole ale saielr a pute data ede plo sg (EL) pe in prc ft pe a Neer eee ap 19-inch erin + reduces acl mais extcellredoaee inhi produ de olagen {ives clr mean + Roser poi elle Teele mezangil, cule mseulae netde {best vse reducers expr etre sui cononeti Feces clei de che okie din cele regi mons eto fei endl ‘ete neice pe tomsnanies glomerular. “Acese fete rcpopteive sunt decent econfimae cin, exstnt nae pve pos esr le aor Wau TNT til GREACE wy) dar ‘Tate clr nef sle sr wit prospective mari SHARE). Pn grerenrext dteea sufn latl eno-ptcctr al apis ipo ur 1964. Tretamentlanemis Det enmic secundare BCR ete eres hemoglobin si el iba 3 fb oat fe lvesgaile rosa, nae de al BCR Femolceogra "complet tani rtcuocte, fein eich satis ariel BI col Recrlurs sinrmaaneic It yacieni cu BCR st 3 da ft anemic tebe sat oc an In ace eu BCR sl 45 neil os pat 6 fara pce in pogo croie de del cel pain 6 nl, Tatas ‘Scmil rm ice tetsu trp’ etme cu i, aumento © ‘Shing trated sige “fe a pct firs tare, 8 gis pacen sub tape cu EPO, se ecu amet de poe ts ie ad Se Gore ees ane inva leet ub 300 mp straints ab 30%. La tie Terai cu fee wcbue hate in conederse alt beetle (aneoces “ple, viento arate ca EPO), ci pose ea {joc arma sau loaders pe teen ang necuoset fe) eg cle de amnstae since de seven def fx, capil sens pl eerie terior ce, compli pce ‘XEminsvaren incor doze sea face in presen pesoal medial, pet fenraptite anor ac advo sever valine uber deport de Fevecafice aa ‘ten samen cueitopitin sev face Ia psi su BCR dun corsa stor ene de anemic est de fe su sor naar ‘Sisiorcarcs femelebine ial ae, Vor hse fe considera posible ‘iate aivone (tle vaca cerebea, oozes ast Ase si ‘Ufoncntne seal Se veceman pre nates amet cu EPO Te ci cuneplr tte de neopla sa acid vase cera ‘Nu ac rcnnari ies tamer ea EPO la poi u valor ale618 ___NeFRoLoGiP-reisci TEORETICé sLrRAcTICE emosibig > 1, La pac cv BCR nein Hb <10p watamentl ex of indvdulat foci de ata de see Remote, essen tefl prevent stmelor secre ane! 9 cee soe trai ct EO La pacer cu BCR se 0 casero FPO a wet alo le binge 10 peu eva sede scesia sub 9p Die gc smuan st erpoiretf pa: etvpolia reorkinansh ua (lik), dabei al, CERCA. (Continous Eeropitn Recpor “char mehospeetisiene hcl ~epoiti et) ‘Derbepoltna ta eeu sen de grcaia dvs, un aalg de ritepeeina cu Gut part splctare l capital amino Aceien confer 0 tabla ‘etal supine um ceranee scr erin crests ier de “nina Is spn sou unr, Factl de comer ite eposinn altubta earbpoinum as ete de 200UE 1 ‘omens fetch» emis cfs de gent sina a ervopicas are spt f minal eral are inp, cu a 8 CERA. (Conia Botirpectin Rector dees) Aces are dus de injtiie. de {josie 130 re, emi aia unr Hematie ee un pond cre miners cecal errpoiine, fr ven ico sine sacl Co EPO mtv su ccombin Face parte cule in Stl de fact i Avanjele promis sunt sable cfs eae perme tporiarca ly tnprora came sie famacodinamset ets, cre 02 ecteadnisrare una, see eat ncete cv anor an. Fsmiiad samen PRCA (rare ed el pasa Sabentarl HIB pect nor nami St iii onipt a wor eve nln matali HE poring fa) ‘cet mca ar pienso produc ebdogend de EPO. Sing prods de {cn gen se deve st e far se ante oal Se vrtste dese rena tratamental x ASE atu cin vaoie ‘eploine! mv rete pian de area tania cae Neverisene tame! EPO sig ensmerte abel “Tal 1, Calan BCR Cae sesndne ——| Gai a Mth ASE Ran Rie SS mbes ‘ems SECA, ARAL [Ara Nee eee eee 19.65. Tetamentluburtilorineral ross toc bol cronice de neh Trane bol sous Ta pice dintizat are ca obectve Wolo stderen ‘cluror rida defor pormaiztes calc seve ecu meni incl prthomnll ite de? of 9 ina speroa ali defers (a fae arse npr, oni ino comma KDIGO 200. In cee ESieveye hipsters spe fal cd cen toes an fstor 3 te ingrtant m usl pets pert secu i ma kes ea bala ‘Siioeccilet Nive ese efor npc ran prs fsck ec, ‘Sete cu un i eset cli vnc, alle sa Ge esi not ‘ci ball fel ri Pin penetra a elit Sti presecive {fret eonseze heute meni sn core esr in inte normale, ‘Rurmandiie aul dette arnd-se dou esa ebscrvatioale ae ‘Gmpnatat‘o wos ie vlc cescle de Tor i orliatn enio- ‘ear Dey ghd! KDIGO 200 pu recomands un ier precise eb ‘pew Festa, cnadrim c ita pr ose ate itera 3. Sm mrs slr cewere amoral falar a fost a de SS mpd tail ca hrf, hipofsitenis seve {P-06Smmol se pote stocla ot © morale escu i Frce ase Shri oul uponimade eda pce daa 19.65. Tratamentl perfsftemiel Minrdc detec care tert sor deffo dot 800-1200 mei sau ‘hivlnal» 400 mpgs rope chein ment ofr fn ie ommafeAcese mat eet plement fst ej pact aes omnis ricol lui protester. Date alentle Bot In ‘at sn product lsat, tue oeoare In speci col, poset dis ames tule aunt, tape de cera, aii limes THomadaize reduce aproxinaih Sf) mp fer per $e 2400 met) cit mind nh nor apo exogen apt. Fie de dai emedbiite erent sas co sapealeje al ma eres tional lace toa dor Int mich sur 15208) acs Ter ind drat fate ‘Shel concemier de for bt nvelol membrane de schinb se realize ‘spi npima pre aie, ‘Hutumcra? mecamener al hipertotrenil cprinde mai mie case de neice F*Chelmri de for eu comina de caleu (carbons ace cen) — ‘ere pin ne mdiaentas eaten Fipefositene. In general ‘Bum ming Ge colsiv nw cle sh deplgesch 3 py at in car ‘perclcome, sara aesora webu areup + SSctamerl- cu lt eet natal are copie cl and {Stel evan dea produce ipecalceri «+ Carona de nani ee un lt sao de feslorcate connec. id0. [NEFROLOGIE —PRINCIP TEORETICE SL PRACTICE i a a sevelame apse cue dip «+ Shrnte de nia acon principal apie hier pn ‘ia ania 0 ind va deceit fal sh aculres alumi lyk inlet oat sondage a foe tvere Renata, peu soe. DES cic mare ose mera sr re ian pcs Cue Commit tne carbonutl de ager suse e clin ~ pot de otra ts per etamentl hperfsitemsel, cbinind esc ‘Setar p bese sale cu etl enefc ae magne, ‘Segere rt anumit medicament se fc in foi de sal boi real, ind ont debe sm de esl vee de davez ale cles vasclre so le ‘Sefer mc so dai pet a i nose este ei, dah te post de probe hole ease). 1865.2. Mentinereain inte nomele a ocemieh {rcuie mena te noomale (Inte 84 9.8 my) pin admins de repartee calla nafs rine po a aor abr nena Teli a ede poclomi, ou pin eape dina de anind D Sot algo vari D ln cl cu perce n pi, la pase ig, ‘Metres ie noma scm ac eaizcara pin area unt lat eomenmae deci te 1.25918 mmo 1865.2 Trotoment hipeparatioiimatlsecundor ‘rsamethperatdecl secon ern un obi pckenal ‘BCR. aca Rd ssa eu un fe eet Ge mrtmoralate. Aces obey ee ‘ales pn nemod nl urs traps care open Tommie clei, blr de str, 1 Miamine D sta sau alo de wins D (aril tania Dating Taha sere de PYit uzren sein fd Uriah dow de opin ‘Mpeacmit a hipeonaeict saab some amie, Pe igs eet ‘emetaolanl fst, vaina D ar eet poop, xu. Tuomas protec el De scene tnt erie flee amiptcinaice pte de sree preci a nivel postr 9 {ncncies cu sen reniangotennslcosieon pein fhe sce (aint Sen dspoibe mat mute prepa, cole ea tliat find ‘Stell doves allel 4 Gakiminee unt ast epee eae se sensi eto de Ga e'i nvel prstroinn chiar gp mela olise ale a ‘Sacllr hb af seria de PTH. Cnualee sng repezetant ‘Teint minced abe isin cal sa oo, shen PH {is cree aco sa otitis + “Pwattidetome et ni a acetic ipersraiiionseverperstent (OTH 00 pend In eda ements farmaclog, sau eind tamer Spulcamena ne lr in cera fete aves. Nee ee eee 184654 Abordrea ol acinamle {ean inal never esos sent snc cid ave de a fie ox un aie eh tt sl de let uo constr de ens care hn pes 1.25 moll devrece nest asa aes pce repens un import ‘Sul pen seria de PEL Chest de foster waminaD tebe eva In cleo prthra seu carci st nib ma ml ere 19466 Tatamentl burl deconulre Tutbrtrie de eagle pace cu BCR st repent deo mosiene a ‘stl pine eu peng inpl esingere Diz deca 9 > [Sin HD ptt 2 in DP) sacs membraele Iocompatbe ishsx ela pl de singsas proba ia einen mato toxin temic: Montene hemoragie sat al pine tn ales pertoala compariy emodiin Se nsunun pogamares tren chiral joe fx 12-2 (roe dup sean de ND. cele eprint pt pista 912° ‘hiara tin cal Ropar eu euate ole mic In aru ert 9¢ rte inimiza desde eis sa ie late anconglt. Anise Dota de prota (Le 10 U hpi aia In 10 mite) poate f tein coniere in cz singer sbundee gis prelim retest 194. Yratamentl manifesto eutanate din BER Aor piu rst rience pin excderen aor eaune tai fiotar "dematta apes, manos sccunare hepatelor cron, Foon su abet ahr ‘Opin lz! ist oarional sca pevalea i seve esl en Cro dash nbrcde nba sinomaniog= {Er prnodetoni sea demons un eft Doel in amtores pr treme, Administra topic de cee cnoleme ete. pine prinele msi: {cape n cin rerorconmaisor. Anthstaminle de grea a dos, ‘Nir tial (24m) ar pts avatars PU ori (UVB). in ‘Srede23 spd, ames pl pe periods de pl lie a Tobie ‘Sunscreen anesigen a tere de ung dra. Administ {ps dalek Gabapentin (200 mg arellveat pital. tm cual ain {nice se eonnnch eee dma pei seven cel betas 19.468 Teatamentl manfesteirnewologice dn BER “Te neusopc ace BCR poncho aleee str nerves ea ‘Limes yee Mantis svere le estalopate emcee eit Sp eletanin’ dea noes lie Aes singe se ei posesFROLOGIE PRINCI THORETICE $1 PRACTICE Corea annie eu eritopitin se soci eu amine fant cog icles clewooneflograme Tstentl cu aalog de wanna D sa Ghocaket sa dnadt benef died cansderim_parahormoral ca poss Seavtonint Policaopain pene popes indict deems recess Inge dale in pasien ow BCR sal 5. Simpumee oe umelorech ds inieca uel tec de sles renal Darren neropth oat faa lids ect (ex emioplinu 1025 mg pi fa T3180 mg In eles) ‘Si aulepiepe (x satamazepns 200-400 gp a dca math de 1200 ‘genie, 10020 mae mas 600 mg) Ostapeinun ete zt uot tn (Pern ner ry ec ie cone earn eta dip BC, egress + bac ELM, Mein 2, Zima PZ Pliphome KR. Aka KC, Dusan BA hin hn ES Ata Rr eed ho ion. Can Dace Conta an reso CDC) Prevalence chiki Sie ‘oases tee Unied suey 1998200 MAIR Mb Maral WK ep. Sov sa) 6-18 4+ Cho trea Mt, Mach M,Z A Lamb, De Sno N. Loe ‘Sic: ten ihe plato Pens seated word, ad wae ‘oe aoe 0400 + Cok I, Rao BC. ese Ty Eman G Levey. S.Pealense of conic ‘Sts dee so eee ey tom's th i US ppt Tid Nana Heian Neco Examen ery Ky Di 2084. + Cine a Sete A. contasinsey 0, Brot Vliet A Obra N Sin RG vs Gubeictuenr Sage Ses Sy aout i oe ‘Actes weer MCh Sc ar 2008 Oe 3095-31. «Eee eo Hemedan ncips Tomte Pcie. Ca Esl Domi + Hin 1 car Bc at on Rem a {denen 5. Hole emt Camparon the ena Choe Kah) ‘eps an ESRD Rie Sr Nb 275 284 26 Heh Unt S207, With Chars om Trend te Heh of Asians + {CGC hasnt Comer Sais 20 «+ Keih D8 Nichol G. Av log CM, row J 8 Sih DH, Longin ‘Siac does mn npn he Kes hee = ae + Lut At) Namence Dupes Popation Dyan: CuretTrn and Longe ‘Pa nolan vo Nope 198370, 202 + Mest Gy Cape Dy Cove Moga er My lbw GG 0 DESIR! Gen Cope Conti N, Neocon ed etal opener thew b Remateewstion crimes Crt Sayeed) Nepal ‘nla hen 1, ate, s ember S00. 29798010) 03 ‘atin! Kidney Fomton: DOO Clini Ps Gils or Choe Kilby DRS Een Cmnacon an Stason tw Kun Dis 3981-9000, Rin Be Ditech. F vn Estar A, Gg) My Down. Levee Pet ard O-Keter Re Gaue e WPrteHench NM, Sa SF RepeE anes tan th SAPALDIA tam Pevace af el psimen Fara tegretol oF Sher sapal uns) RD Pin 2, EBA SEER tive ois ance Aon al ofthe EDRCE sysop eS ueml ds nhe Caltn pps: Remit fe ine Re IRC stay Kn eV 8 Suen 9 (5) p68 SfarmnW-B. Faget WD, Us MD, Since D Langs. Gta Se aco san cen if fata see of pest ore Fw perenne DT ‘Teves Kea Shop! Sa Tn A PskndC PErM, Sis ‘5SRsnt rc edie Daa) So ep 6.373755, 208. {Sn Sm sen US Rn Ds Sy Aa Da $595,200 art Trost netertee D: Prevaene fd Sein popstion ‘Sea ow BE Pi Fh 8, {Sve rode io Sonu foe pate ss of hah he Eaepan in ‘weenie Baro NDT Pas (280)caprrowwL.20 ‘TERAPIILE DE SUBSTITUTIE A FUNCTIEI RENALE | HEMODIALIZA 20a. wrRopucERE enti bte de 10d ai den dese clase boi rie de ni exit is inks proposed seer pce O fae eal ae {seen pry sexe ii rp In on ues sco ek ‘olson dich reset in rum nxerab progres, ce des rin apr cls, ca mcode subrine fnc eal 5 ama a peony 3 de ae ft ews pois sprites ama de mica (2 pec cu aectae real tal tormia fm nese Uae. Peta ‘Sade at dilie eae des veal hameostaia ima 9) exacts ‘Seti ne ue Yer ome 20.2. MOMENTULINTIERIL ‘ott ce tla cronih de inch even sre sail fl, pact bie rel at ie Ct palo, pots terapa de supe ani ele La lh pln ene pons peta proximal a moms nearest Sal BCH ete sts seek informa eels pear pce gud © pero uk inven vei cn ysl in mod todifona inert pent isepres dari sit somece sinpromele remit combine cu rere Mccimice peice din sigs §) Pins Ex smn parame hice nlc ecesates infer bemodie= Peart plea (idea de rect {Eels nop rem pos cu cee lie rum oii, Stent nln pce snare severe cr (ese ue + emerge lnc cost senda uremic cae use 1 Hipridere react lade,es [NEFROLOGIE -PRINCIPN TEORETICE SI PRACTICE _ + Hiperensvne rer neers medica stibipeesin 2 Talbert meee prs tat tempi comer pepotseia scidrantaols,hiprelemi,ipoalcem ipo ‘+ Gren vt ce imped limenai + Naiman ‘Assen ou un oti ameniaitor de v ia, asl int pf Nate cally ake neat mat pn eae pny ner lz, cee Inala olan’ ia sade tee 9 pul coat, depres, pts Sinica neti ‘Gide pac iil suger dio tba nat in moment Incare alae clearance etnies eae sab 1S alii, cence Incare pict ete msnpmac suave 9 rev wth sab hu te pth Aces ghd facie tas dee in vedere nt crc vi ‘tera ogisie BCH nips modal apr vl cern ecru “asc, adminiraren eropien! femora pis eine leh ‘ial un impact jr aps baer bli renal coil ‘umerose studi oberon ex-con a sige jer ish ni devreme a uni supvieues clits vet ated compile cin, sel net i lin ead bret nn nance ica Feat relativ rescue ale ede Tire glomerular Crores masivd t rma d psc eatin rogram rn dela ds ate! ere oporionais slo fiance unane mplie ‘Sl ma recente, publ dps 202, compart space pacar la cae sna al Ia eat vant ale loon ees Set ‘i cberafrle, ce nl un nan Inpresoat de aces din baw “te ip eas (tezind USRDS, Bare of Naa Hath rnc a Tan, ronson Reps, REIN Fron Regiiy Canadian Ong Replacement agin), a demons tedueea progres 4 oa ane cg Sal ‘is clr ma cst le won sein Ase sa aed overt coningtoare gi epodctie in legit epee 9 mace Inte wn rane al etn are eres dive res nh ‘us ak suds oberon suede, reuters une faces onelzic: morale fost mal me apie ete nia lia ‘vl lar ale nei de leas glomerar, ‘Sail IDEAL (Die Iniarng Dulas Bary and Lae Sma) ote sings studi prspety rndomizat cea anal dach omer ine eat ‘Sec nflonten moma Ia psn cu hl risk dein, lnm prezet nae sud 828 de pace a et admis nd rp hue spurs” sania de ade itr poner a moma Inigeni"dare Acca sun ¢ detontat ch ignores elarace de seta ees daze! pe taza simpli isn a (Compact lest rea cere de 0-14 in 1.7m in ese sinptomely elt montreal ey rep deeb fm roe Pad sri sinter sau pin la un lance de 3.7 iin 73 maint © min cu an» aie cups econo porate de bust persona). in cone, datele asta wero aprelren fence! ronle prin rating src fan cearance a ratininl exe nfolosioare, car are, (Hinder denier hema. 20,3, PRINIPIFIOLOGICE- MECANSMELE TRANSPORTULLISOLVITILOR Urinal epi rer ur process de eb seri relia cs tm coosim oxigen apc nivel epi tubular Epurtea. ei "hh tile opens dor de fore ice de ric amet ce f= exer In saa une rnbrane serene Conceal, ath ‘sna semper pat prvi xo foe perfor, cu numero pot ‘Su gir. Molecule de ap ele eu great molclart mips prin por ‘eran nt se sit ma (ex protec) an pot ee ‘Sci care por eee, pt port membrane sunt tango prin dd ncaninme ete: alae (coos) 202.1.0f6 ese misa soir dinsn compares in ll, inde pe rant dd emceovae due cok deus compartment) Find rer miei Trowniene Moelle mii micipdose La 0 cot al mare. vo! ge ‘mcrana ma des, af tno lr pin embans va fmt mare Ca ct ‘roel oe cuando gol memati (Gen Bur Figur. eens chert ihos [NEFROLOOHE —PRINCIPH TEORETICE St PRACTICE Reprint picpl mca de pure xis in tial lize aoa2.urresiare Mclle de ast sant foane mic, ces oe le permite Sh trveree sa cesses cmipemestie, Uliaitaes are he atc ind ap, sub actions {Ector irsce su osmotic pn pia membrana. Ace si care put bec pn port mca, ut spor dat cap, pase ez igre) ‘Tcbeeiehm eh act sbcaniam mo Spade de gol de onecie inex Jk omptannt bepress. Pigue2 Preset hase he 20,4, APARATUL DE DIALZA Scop apa de dirt ene de 2 ace single si iia Issel ‘hh ifndef omc po av i bemodale eign i este cet ngin xtacrpor 9 ia dirt (eta 3 20..1.Creutl sanguin exracorporest ici sangun cep I vs acceso vse, sngle id yompat de it (Sanat pi To ell la de inti, esbe shagse find eit Diet pin intel ici venos 204.44 Cleo de cbord voscar — ete repent Fi de isla su poten ‘etl anenenne ede ctrl vans el (eas). ip 2 Tole de saat ane rene om aati / ee LW ‘igua3Preectuse enalapril 204.12. Tubular — ot lain inal pin casing alt en pen Ta dior ini enon pin ie sings cll el aizorIs occ Ail ell ns arr ot la ie ec enese Se pest ‘opame de art scp detect przeamovia pander rl 2 ‘Sheng sanguine fm iil sanguin. De asonene pe tcl ior $e ‘epee dipoatve pent montorsrs print sngune da cc cS 3 ‘Geponive seve de unde se ome ra sng tu init eden intenosninpl sins ai 204.13. Pompa de snge — sin uel sangui la ivelliteas crt to bit motes dependent cate sor vase. npc pone Sula AV se peterson debt angin de este 300 lia Inca sera ‘eno coal ease be ne 20 250 mln 204.14 Doron — cs lest in ook comparinent pin cae cel sigs be de 0 pare alta de cept, Spats de0 mera se Denicaily Dich single palit ar vine Ta cont tc, To mp ‘cnc onl arn! cpt on schimb ma mat ven eI Draco, pnt paris sce chi ipo ¢ eine grad nossa doin de cigere singel pin lor ee opis ol lates ioo [NEPROLOGIE _PRINCIPU TEORETICE SU PRACTICE Pir de iis tue sidelines sto coni pent ssguarca nel see: + iocrpabias 1 Gt rest de opr assur wie {pdr init de snge su de le componente vl la iv membrane Esch + dimes rede 204.2. Creit aett Dial ex consti din 9 ines puri care au aut a omcnati bine defi, sake pots, cal, magnesia eo, bot § ‘eet Acco concent po Pfau pet ll, fc dep ngs fia un cen ca eco ontop Pon un na cu cle scr ec) Tounl Se acu fn ‘Shy arm paca da sch de dain, al net ated sigs ‘lel ont late pa meena sempemeniy, a ante ees ‘stem mare inp sge spre ain 205, ABORDUL VASCULAR Accel atl est ceil pens efctures aor glia de hemodii ‘Mcrae I pace eemi ctype eoucete ori moh In ‘ces catporie de pcm Cele 3 uur mje de aces vasa st: la Sherorvenons nant (FAV), prem vanclarh arcno-venaisl (PVAY) $1 ‘Shee veo ena (CVC). ip 20- Torpedo a Moraine genera ino dltp ater ens cera eto 40% sma mate deca vor care a0 FAV sa pote vse ndependet rena comedtidhor 9 aloe Cc. Din mele, la peste 75% dre ithaca se iia pe CVC sorts pene n acess {escolar permanent func! lari debu Geto ‘cel atu en are nde rma er 1 Saposedeo pte save") dang + sSeasciez uo est a compctilo. ‘icine cl ip majored ass Yas nepal Scher in preset, FAV exe oir alse pins de sor vances pleat malt rome 4 cretinin seret> Sa {oan decent = 25 imine 1 Gnd ndspears nce ese vascular n mai patin dn, ‘Asn va eum rebel supercar le pale va nia cl ta Ine pen efcctaren inet FAY tv, piel ind st penis e vie uncoarea venor respecting. De mule or rests trie» ace ld ern rice eles dln seen elche AVP 9 injeren dizi pe acter venos cena, conse neptve ete asop ‘peal pe omen scr ed lang. send ee rer pinta ‘spa ners! panctonr n scopvrapent su digntcw membre Speriornon-dominant Acasa merdcerebue comanica ners meld {fai pecan tote tl de eins interrer patente! {hiram sere nefolgie 205.1 Retin sterosenoash Ee contd toad suber cre cig neo ae 0 ‘Sea in ver. Co uma, Yn Se at $s nosh atealzare"), pt ‘Sorin yet relaes seal eatesonorel inp ede de modi coi Tenpul pina la atrarea FAV eed 12 spain, 205.2. Protera velar arterowenoaes PVAV const ns-an gefon de poitrauortlen past cipal cao pune ie ores went. PVA est opine nei FAV (lors al dite {esp-r ine), sr prefer fat de tte venereal. Tipp in anlar ted el de 2 sapamd ap emiereaa [NEFROLOOHE —PRINCIPH TEORETICE St PRACTICE demu i even, co vndesaes plait charge, wae gree ‘ssc apal ca uj inal epnetionare one sett nc ‘el estate de aren ene: rtrd olan 205.3.cateerl vnos central Caurl vena cenle (epore 5 pemanetecni) in ade ite ‘st pme” pn la derolarea net FAV nts da aces mo ee fet ‘mot gent Remodel soe Po lneate rapa, po wlte ‘ait oun sang ssid (200 nina area ete cat Arde modi casa (ols, ped de trap ens au che cardo- Stag): Septem ena gun er secur a fear owl de isos al cater dep de conde anomie le pir, presets aor afin vce we evitaren unr compa spice Ia Packet cu re (ex tcl pcubcorak I rf ul cate Th ve ‘blac Tun pin cu Bronopremopati obama conic ee), “Gidunle KDOG! (Noon Foundation Kiduey Disane Oucomer Quali Init) comand cx flea carer singe, neuciate mu e mat ‘nae d's Stamps Yona ines eS penta Femara 204. PRESCRIEREADIALIZE $1 EHCIENTA ACESTEIA (© prosems cenrals in management puicplr iota progam ctoic de Ness clea efit! asta Dot urn ell wet a ‘fice desrece us vel Seal pat sget al und pate nec {koi linen Montz ipa te de bene sue, pad ‘St de ape apcieren dala eu etopetn,aminisas pen cometin ‘Stoic majoras spol wri, psc pe saat 2016.1. Ines opus rei modelre kinetic ured 206.11. Rata de reducare are (RAL) are reduction ei (URR) iepresneh determine par vate ees lie! $s bzeza pe Cospl uns rede re, cone # ure pe aca yeie de al. Prenspundnd ci res predict ee de 100 med ar sn poli de 25 Ip rlucte rin 9 wes ee de (10025) 100 = 0,75. rn coven RRU, ‘si eximat aun pct, et vals RRU nena de fi ee de 75% 226.12 Defines UV GV define sun plas eprat (Kt) mpi la ola de isa ‘eee (Wrest eornce coe a uefa de a rds, vod mas 9 veiest persona" repens drat eine de dali, op 20-Terpe de abana fant eae 3s iar yolumal tal emp in corp. ‘exit alae ani scp penta RRU KU. {Ghidue KIDOOI (Kidney Dsese Oucunes Quy Tate) 200 curing umole soma (peta poe ance eal eal ? iin ism) + Doza nin adc webu en KV 1.2 (Gan RRL 65% {ovat ble leun AZ Ge 44 (au un RRL de 7%) 20652.Evauarea etc prin meted ateratve Deteminarea KU nu et mst uranim scepit pete evaures ec Irmo. Ale metden fot Gervais a obi SiK ce teste normal la ‘Ay purmets iea de ein daze ce we coset oh an res de ‘mortars includ tpl edad mal mare de pata of, we peach inte 183 4 200 mgidh un secour send de efitopncind @ medeamene tthipenensve si semne dente dee falbuminn sect > 4 Bh, felestral plsmate tage 200s 300 mpl 3 etmcenate platen ‘tenn redaiie > 12.5 mad, 20:7, COMPLICATH INTRADIALTICE De seg, © geliah de hemodsshinvihlinh qi aden speveghen nei sun paiet ou pane coorba se nse err de complica ete inmadalice. Tey, apo Vase pans cu mule comer fronice sic len! itor severe eengcatilesnaalice pot Fecreme severe, chiar aneinor de ah Princpaee complica intra sin: ‘ipsesianca nea, ‘Ceanpel miseuae; igeresinen esi ean Arie carace: (Gre. ase: (Celle tip mize nee leben Reale sles pana Sina de derecho dati:ow 20.8, METODE ALTERNATIVE [NEFROLOGIE -PRINCIPU TEORETICESLFRACTICE ata moral pair alain pram ernie de enolic eimdne Inmecepl demerit 3% pan) Consent nea emote (Sesh io ait swirl ba (tot In mae pte une ‘Staudt opener sm) In aes aap cost a In cot coment ‘Siri cori eomancne dev el nto mice eeprare ral 20381. Homoftvare jhemodiafiteare Ini rin sitesi se ext fine de nes pin late to ‘Solio dai dines pr (si emi rte) se es {reas Ta Aces pimps as. devotren bel tech dere ‘eofare, pom car cna mae de wiraitt (ai mut ect eesat ents tess enone) ee cpl eso cu infria nei ant de eid penne ona eset rd. Dept henodiiza pezina © apace de epre sli ri por ma and themes (ox {ets bemoftre prea mane alia sla zai eats ee ost ner in comb coi roe deat emodifinare Acs cid ese folosoare devarece spares act ‘sli reste molar mic pe clu pouate molec mae 2082. Hemodiaza otians Regine mai vec Honan ca nic hor day homo SDHD) fi hemoditi hangs roctuns lo hows nocaral hemos [iID), Arnett eft i adem, a acon SOND fn onde eprare recuse min pete 120 ia se henodiln empty cele 120 de mine conocutve. Acca pure ‘nis apie 4 wee (ipl a soir ct pete molecu apenas) ‘Ste conse it erate de de tiie maim (dr grea ‘pi mat ample sng az, cit i srt malcomparinete ‘rp uman Azada dest alin de iscura de doa orev dering ‘adie doar SDs pe ents ean te de sali cup md, ‘Geveres amir de gedne va sen in ft on relat © ibn ‘ooance-l spinal ea 20405, ‘Pn fled NHD, 3 oie 0 teers seit clearance a sobine ov peat moc ic, i acl crate molecular mae {Gearon sir fof eee chalet (amcor ciel mare) cb Ineoe cane ingen apn Aga pin liars NHD a ene essrtfoosfenchelaerlor deine, unl "fucie resid chiar ‘Splmente ofl din dat pen a preven hiptosttenia (op 3 epi se substi fe rena os 209, SUPRAVIETUIRE Morais pic cu bal eric nici (BCR in sail Ses, dps fen am pea deja, pron, compra dor free agree de ‘ane. Pipl aie de dees ale patent hemdiala (HD) cnc sk Tegate de pallopn cariovesculars (CV), de inet, ce male sau HD Inadesns Confirm Sie publi econ, rc de cel pci aia, fo up al 000, reas, compar cu psoas precede. Pui ects dese dou cateor de tor cre ined moras cen dla cone: lea de dln (lia odeeva, ase vascular, Irembrnee de di sts dc 9 ution opm sau vee ur FH = sonra iis ss motor) sa indopende de aia (or ‘stat phos sau prea coerair dale ol carver ie) ‘Cntr dso in Stele Unite (USD) supaveres mei ete i ‘ir pen hemodiia ca vista capes te 40st #8 en, Said ‘rama Is dar 4 as pois ee eva et 65 dea Ls psn “ars acs vl sunt compre se le pacer cast pula, int ac dec cel le popultisemenfeArelare eet tale post eliza prin pesca doe de iihoptime ev ae tn pre {SKU Ge 1, eae comodo, nue us mal sts ae ‘scot tres nolo mablsma mina x ct ea eal “abel Indie coool emo npc temic (eri cova coms) Idee tment nh Ditech her seve wend wom reenact eae ice set) ‘Ur signa ee nestle emi ‘Tose dali ats medcamemens)| ‘Nara peieh meme ‘cata at ‘eh eh as, sos Sica hn epi Tiers srr con pra tment Tir de mea ope6 [NEFROLOGIE —paNciH TEORETICES1PRACTICE Dees ni cea rap etter iii i eh ‘por pice nk pager Ft nee bin ‘comrade Tipe wc unde a ns ape Ubon rie ete i al eee TR Shai ke ee Bes te hoe gr a + Ab KC, Glen CW, Teun F.C Body mane den, die ‘ai, and savin soba of te Und Sits Real a ya Dat ‘Sr nl ray We Ste id S08 397 Chat WF Yingto Na Seen Rese tl Asoxaton wen estimated ms itn te ioe of asad mony. CMA 011 Sa + Ener B Ay Bay Py Blo Ly eA doesn antl fey sete atta Nolo sai 1 Diogiie 1 Blake Ring TS Hand of Daan 4 Pade inet hr TA, Momo. ng Md 2070681835145 {Le Va in W The sin of al elcome! Theps — aoe ‘Fe Deny ¥ ng fa D00, ober + NIEUDOG! Cina Pace Guns he Veer Aste wpe 200, de + RIDOI Cink Poe Guideline and Cla Pcie Recommendations 2086 {pane Homose gue Peto Ds Adega as Acs, ‘Keine Dis 308 8718 + SVS: better WA Dota Ress el esti the sa of aie incase Nip! Dd Tat 10924 Cop 20 Teepe de abe fnctranae _ os) I DIALIZA PERITONEALA 20.10, AVANTAUELE, DEZAVANTAJELE,INDICATILE $1 CONTRAINDICATILE DIALZEIPERITONEALE ‘eds de onic, in cae s flees 0 mem de dea ial traci, dais prtncls (DP) wars © membvans Bolo, a ‘aco ~ entra pertertl Et erm i a osci s ing Sin! find dct HD, ce poate lst ave cape de vrs In ema, De plan mondial, aponmaty 1% dnte pace ce DCR terminals iia ‘fone sum rt pe DP. In jar ast cs proce! xe poape de Maras slr a sac DP 9 HD outed puncte oder af supra 6 alrat spitalizile pier cl pun In ri 2-3 a terapcdlid Cele dou mete au, na sane dentate reine 20201 Avanaele DP in corpse cu HD umole: Conrad a oem aT (spin i primi aide DP, dtr aie (UF) ome, emis + Pree. mat fh ronal recidule (FRR), probabil dtr ‘abit TA" a wolemi, sre previne ait chemin peretunes ‘loner, secindae epoaie cece Ge neste anal especie examine yolemi ce carci pace tat pit HD (DP ind o meds de zt commu, In inp ce HD consemonal ete © ‘eons 1 Pasi cu DP nce tanec ropa kde emia mic ‘ect poe HD, pot art rere ra be a FRB eet «odie fenogne esto) abel per de sige sun eas HD + Redacre in de neti vine hematogon eat val HIV) dtr pe acest sul iu extocrpore ‘Posi © ma und cata ven compara cv HD oferind paenilor ‘na ml iterate in rgarzarc ie profane 9 ep br + DP munca acces vascular spat sofia, five atari eronall medal de igriie et ms es. In ones, come DP pt pean sit ned cu 2% mal ml det le HD. 20102, berovntjete principle se DP in compari cu HD, sun uit: + Ric compleniir neon (geronie, nei le oi eeie s ‘lett subctna leat de DP + Dag maa i. «mem ere + Compal metabolic alone, price siden638 _Nesmovocie - prc TEORETICE PRACTICE 20103. nai OF DP poste presishaproape I ce pace eu BCR tril infer de ‘st Prefer piotlr petra DP su refi! HD su dese in lege DP camel al de dali, cu cepa connie medal ols DP poste inet nod part clr eae oc nds rare ecole [lst cae blared nao race err Pei paces cae at ‘zon (bt pot aedinsea DP) se pate ope pest DP at ae ete ‘fecal domi pier fe de ete oases dls specs, e ‘cate un ete la tnt coresptor nth DP Di ee sngr eras pss pin cae ace vse pera BD cote die sa npon, rst = 00 trombone venete ex, cu achemie everks exremitilor se tl tei venase mules ‘lta nie ccerss vnar fo moto cpt mit cmt, de semen, moti pony cafe DP ese moda de Gach pretrat It sc cater Vt 20104, conalnaatile OF 12010441 Contino absolute oe OP Dest sbslt nora murmur ish 1 Impose oir cea perineal + Refel dle de care pact. 2 Diino membrane! oritoncae cps elias we DP adc; 1 Tature’ woes sere ale pact, cae Blea eapactten ‘fects cores scinbusr (Sa) 1+ Dajte majre neopratie se prea abdominal (ei, even are Ineo aie fin ou ese cal enc 20.1042 Contraindcote relive temporare ol DP Feil pata hit i hemo ep give tn esl DP, de acs {se ecomasb se zl cinca aint de niere acs Hele arc ete or fn eal hil Ge Glia ef DP. 1+ Obese mri ace mail opera de implants a cetcru e DP {indscnrs powtoperstore. Angers aranetlor DP aleve pate de “Scena eis sume revesre vltme mr Se ia). gle DP poste ‘dtcina su agrva probleme repo tbo ating geste Taacet paciet + Pal cum orp sen pobre de vider pli tbe ins mr ctrl robin de complain! de DP 9 ise eset (egal de ati dis enua pedro poe in alia, La pct ov core vial rear anc afc aco (oc ruc a auc) ale mine, azcodninstarce DP este ie on 20- Trp de bia fang reals « spt i raed stand Seo a pesca (membrsh far, set. + Uni pacer ecu fol sprain rn polis glam Sat sepa our pt alec cls ola de dat pers ‘+ Paci cu bol intestate come inflamate sau cbemice a8 us se rec de peri saat cee su efor nen ns DP. “+ Iie pret ahdomina ole pl tick 8 dterine cotamiaree tilde peal etter pestoncl, nei ale tunel utes Prone Un ne eset de Safe eit lspci eu stom ese ‘+ Unepsed de dvr e pare compli eu peo. De aes aecedenle ‘aera earet cote o orca rela pen DP. «Ale conrad In sa ace: open non-cempinocpsin Std vil pseu, 20105, Schinbarea moda de dala de la DP ln HD vbuie lt ie ‘onsideae cr pine trapete urna sai 2 nsutcica UF 1 esiontele elvan recut, + Comptia mecanice imu al secesll peritoneal 1 Pca uct rele ede, Cent isutsn alsmpiomsor wee yan male emi 2 Hipresicedemia sever 1 Oppnes poi (gut de moc sill de ist. 20.1, ANATOMIA SFIOLOGIA PERITONEULUI CA MEMBRANA DF O1AUZA Menivano porto ct fomat in dou fie, parities ae care tte Covina peroneal Petonel ancpecl ee cot din te t= soi esta endl cpr pin cae a cil. ‘daa Sti re Sige chal de DP Meza ete oma dra stat. fe elle pte, cu micrai dspse ye o menranabazala sue 9 ‘daconina Celle meaale st imerontete pn jon, ce 0 pat ‘rset pl sliior Ineril een fet cojenet’ de roime vari ompes din ule (leas, macofge), ve, vase substan nian dbl ep ae poi de dimen vale const 9 ava tin Cale tear apts. Fassia lyre pene (i pei ‘ca auldaftgrasca) deneard idl din cavities trace tind eee uno condertl, U et Mecnibnle Tie fudamensle ale DP sunt djiciunen, comes 3 srpirarea CP)oo [NEFROLOGIE PRINCI TEORETICES1PRACTICE 2031.1 tunes repented espera vir nan vlum de {olsen Difisunes pena membran omipemestl se mane dan DP, robo de membrane i ee jue de membrana peroneal. ete soar ‘ings din capes peioneale det de lit dis caves porto Dine sine deine cali sanaty de we actor 2041.3 Suprafeaefectvd de scinb a membronl peroneal, ate dpi. Ivins demon decapiare ftom, var Se na pin na ‘char el pct neni ert, 2011.12 Galen deconcenroi al slo. Transport soar epind {ecompoct dng omic, respect, ose! de dis (iia). As, {impel DP, res, cei, pts Tsfrl st wana in sng ‘nna pe ind aii, magenta, slacrs act resin ses nse, dt leh deal Ta singe (ert abel 2). Graded concen ne ninge filet al nc sage eters in moment node ntaperioneale Solus sade expneyial ea tmpa, pe misud oe se wealzeaa ella fencentatilor tue! ein eli et ais, rane imesh Poin Ineonee vival dopt chi, ese necesrt ene dill 9 Tnelare ona nou volun de aon presse “abelal2 Tapa dia sion DE, ss Sing Menton eae Di” Niecy im Sie) o Fema Gleam ticurtemty 6 Roca 70 20.1.3. Pemeabitetea atvat’pstonse pet slit Aerasta dein ia vine de ons de mann, de src elecrid i de enfigarfes ‘moeallr Stench octal ch recon wee (6 9) iene ‘mat mol arn eit saance cu mash moles’, mar, rca Great (13D) st albumina (000 D)- Tog ia DP pe deere de HD, Sellars ant made reine Endotel capla ese coset brea prt in ea tapos et iri escalate ip 20- Trap de sab al eae oa icuna emmys gleam ee wen Sse ge * COSC anh apie nt a omprap eps ns pot 20112. Convecia se refit la weer sir din nae fn das, ot ,dtrit poll de presan osmotic Conver teu ed npn ‘transport ales ptr acl ma (peti). 20:13, Utraitraen (UF) sprein waspotl pe pin meta peso cars ase fennel de mec yer dein npn ded oration de pretne crmate, eet de pee tnt agent comatic ‘sli Se DP. Ace grain pine de ait de conenati, ct de pal ‘genome ao el aos Sole de DP) + Permeshiltates membrane! peroneal pena qgertd asmote. Cy eit ‘cesta izarh a uo din Heid Ge dan singe, dtemindd Seren a pda rants xt dela UF 20:14 Reabrortia retoftares) se fers a depres sei a oir Sens inves UF ach dispe evista perionels sre singe pin cule linac cw un det vara. Din pet de vedere sin, rab jac un 0 steal, dorece reduce (uncer emia) UF net ep sor

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