C.

Pathophysiology

Predisposing Factors

Precipitating Factors

Women over 35 40 years

old (47 years old)

Asian heritage

Low protein intake

Vitamin A deficiency

Conception of a sperm and an empty ovum

whose nucleus has been lost or activated

Mitotic cellular replication begins and

fertilization and formation of trophobast occur

Trophoblast adhere to the endometrium

marked increase
in serum hCG
(>15 mUI/mL)

There is an abnormal proliferation of the

vomiting

trophoblastic villi and trophoblast cells

nausea

produce hCG greater than normal

Complete mole, degeneration of cells occur

and they become filled with fluid and appear

as clear fluid-filled, grape- sized vesicles.

Abdominal cramps

Partial mole, the syncytiotrophoblastic layer of vili

is swollen and mishappen.

Uterine distention

Uterus is larger compared

to expected size and stated
AOG
No fetal heart sound

Maternal blood escapes to the uterine

cavity associated with the absence
of placenta

clear fluid-filled
vesicles

discharges

Blood and fluid-filled vesicles

vaginal beeding

escape the cervix to the vagina

Anemia from blood loss

decrease in blood
components
Hgb = 41 g/L
Hct = 0.12 L/L
RBC = 11.98 x 1019 /L
(Date taken: 6/10/15)

Gestational Trophoblastic Disease