SELAMAT PAGI

RM. Teguh Wahjudi dr,MS,AFK

BENTUK SEDIAAN OBAT

DISPENSING FORMS OF DRUG

Dr.M.Teguh Wahjudi MS,AFK,PKK

BENTUK SEDIAAN OBAT

BENTUK CAIR ( LIQUID )
BENTUK SETENGAH PADAT
( SEMI LIQUID)
BENTUK PADAT (SOLID )

BENTUK OBAT PADAT

Serbuk (pulvis).
Serbuk terbagi (pulveres).
Tablet .
Kapsul
Sapo
Emplastrum
Susuk

BENTUK OBAT SETENGAH

PADAT

Salep
Cream
Pasta
Suppositoria

BENTUK OBAT CAIR

Solutio
Mixtura
Mixtura Agitanda
Suspensi
Emulsi

Saturatio
Guttae
Galenical
Nebula /Aerosol
Injectio

KRITERIA MEMILIH BENTUK OBAT

1.FAKTOR OBAT :
Fisik obat.
Kimia obat.
Onset & duration of action
Rasa pahit.
Iritasi lambung.

2.FAKTOR PENDERITA :
Anak dewasa tua
Compos mentis - coma

BENTUK OBAT CAIR

SOLUTIO ( LARUTAN )
ZAT PADAT DALAM ZAT CAIR LARUT
TIDAK ADA ENDAPAN JERNIH - HOMOGEN
PELARUT :

KELARUTAN :

-AIR

-SOLUTE

-ALKOHOL

-SOLVEN

-ETHER

-TEMPERATUR

-PROPPYLEN GLYCOL

-pH

-MINYAK
-PARAFIN LIQUIDUM
-GLYSERIN

R/ Acidi Borici

Aquadest ad 100ml

200 ml

S Boorwater
---------- paraf

R/ Acidi Borici
Aquadest ad

3%

3%

100ml

200 ml

S Boorwater
---------- paraf

R/ Jodii

Natrii Jodid

2,5

Spir 50% ad

100ml

rec.par
S u.e.
---------- paraf
R/ Solutio Jodii spir. 2% 100 ml
rec.par
S u.e
---------- paraf

R/ Jodium tincture 100 ml

rec. par
S u.e
---------- paraf
R/ Jodii

0,50

Kalii Jodii

0,100

Aqua ad

25 ml

f.l.a

Sol

S t.dd gtt XV
------

paraf

R/ Solutio Lugolli

25 ml

S 3 dd. gtt XV
------ paraf

R/ Succus liquiritiae

Ammonii Chlorid

Sol.Ammonii spir. Anis

Aquadest ad

150 ml

S 3 dd C I
------

paraf

R/ Potio Nigra contra tussim

S 3 dd. C. I
------------------

R/ O.B.H
S

150 ml
dd. C.I
------

paraf

paraf

150 ml

Sasa tdd :
-Ammonia
-Ammon. Carbonat
-Various oils
-Spir. dil

R/ Zinci Chlorid

Kalii et . Alum. Sulfat

Acid

0,300

Salicylic

Ol. Menthe Pip

Aqua

gtt

ad

300ml

Filtra
S

garg. 3

dd

------------ ----------

R/ Garg
S

Kan

garg.

II

paraf

300 ml
3

------ ---- --------

dd
paraf

R/ Ascal

10

Natrii Bromidi
Aquadest
S

ad

dd C.I
-------- ----

300 ml
pc

prn
paraf

MIXTURA
HCl + air
Alkohol + air :
70% Spir. Dil
95% - 96% Spir. Fortior.
Homogen tidak ada endapan
tercampur secara molekuler

R/ Methyl Salicylic

20

Ol.Cayuputi

20

Chloroform

20

Inf. Hioscyami oleos 20

S

a.u.e
-------------

R/ Gandapura
S

paraf

80 ml

u.e
----------------

paraf

R/ Sasa
Syr.

2 ml
Simplex

10 ml

Ol. Menthe pip

gtt I

Aquadest

100 ml

4-6

ad
dd

Cth I

-------------

paraf

R/ Potio Alba contra tussim

S

4-6

dd

Cth

------ ------R/

O .B .P
S

4-6

paraf

100 ml
dd

------ -------

Cth I
paraf

100 ml

MIXTURA AGITANDA
R/ Acid Salicylic

Zinci Oxyde

10

Zinci Oxyde

Talc.Venet

10

Glycerin

5 ml

Amyl.Orizae

10

Aqua Rosae ad

100 ml

Alcohol 90% ad 200 ml

S u.e
------ paraf

R/ Calamine

S u.e
------ paraf

SUSPENSIO

DEFINISI :
SUSPENSATOR :
A.ALAMI
B.SYNTHETIC

SUSPENSATOR
ALAMI
GUMMI ARAB : Pulv.
Solutio
Mucilago
TRAGACANTH :Sol.
Mucilago
AMYLUM :Mucilago
AGAR
DLL

SYNTHETIC
CMC
Bentonit
Tween

R/ Paracetamol
2880 mg
Syr. Simplex
15%
CMC
1,5 %
Aqua ad
120 ml
f.l.a susp
S 3 dd cth II
------ paraf
R/ Ampicillin
Syr simplex
Orange gtt
CMC
Aqua ad
m.f.l.a susp
S 3 dd cth I
----- paraf

50 mg
qs
1,5 %
60 ml

R/ Tetracycline
CMC Na
Sol. Sorbitol 60%
Saccharin Na
Sir.Simplex
Glycerin
Corrigens (orange) gtt
Aquadest ad
m f l a susp
S . . . . ..
----- paraf

2,3
1%
20 ml
0,100
20 ml
3,5ml
qs
100 ml

R/ Syrop Tetracycline ml
S 2 dd cth I
----- paraf

R/ Syrop Tetracycline .ml

S.........
----- paraf

R/ Magnesium hydroxyde
2400 mg
Al. hydroxyde
2400 mg
Simethicon
240 mg
Gummi Arab
2%
Ol. Menthe pip
gtt II
Aquadest ad
60 ml
m f l a susp
S loco Mylanta susp
3 4 dd cthI cth II
----- paraf

R/ Trimetoprim
480 mg
Sulfametoxazole
2400 mg
Sir. Simplex
10 % 20 %
P.G.A
2%
Strawberry
qs
Aquadest ad
60 ml
m f l a susp
S Susp Cotrimoxazole
2 dd cth I
------ paraf

R/ Sulfasomidin
CMC
Saccharosa
Methyl hydroxy benzoat
Propyl hydroxy benzoat
Sol.Amaranth 1 %
Aquadest ad
S .....

10
1%
30 %
0,015 %
0,015 %
gtt V
100 ml

----- paraf

R/ Sirop Elkosin
S ........
----- paraf

100 ml

R/ Sulfadiazine
Natrii bicarb. aa
Sir. Aurantii
Sol. Gumoss ad
3 dd C I

10
30
300 ml

----- paraf

R/ Sulfadiazine
Sasa
Calcii lactas
Sir. Simplex
Pulv. Gummos
Aquadest ad
KSHD
------- paraf

5
1
4
10
2
150

EMULSIO
Emulgator

Suspensator

R/ Ol. Zecoris aselli

Ol. Cinnamomi
Pulv. Gi Arab

40
0,100
15

Natr Hypophospis
0,500
Calc Hypophospis
0,500
Aquadest
20
Glyserin
10
Aquadest
14
m f l a emuls
loco Scotts emulsion
----- paraf

R/ Benzylis Benzoas
25
Triethanol amine
1
Acid Stearinic
5
Aqua ad
100 ml
m f l a emulsi
S u.e
----- paraf

R/ B.B.E 25 %

100 ml
S u.e
----- paraf

GALENICALS
PELARUT ALKOHOL TINCTURE
AIR + ALKOHOL/ETHER EXTRACT
AIR 90OC / 15 INFUSUM
AIR 90oC / 30 DECOCTUM

PREPARAT GALENIK
1.DENGAN PEMANASAN
90oC 15 : INFUSUM
30 : DECOCTUM

2.TANPA PEMANASAN ( SUHU KAMAR)

* 4 5 hari maceratio
* Diulang / remaceratio percolatio
Hasil maceratio/ remaceratio :
Extractum
Tinctura

Extract :
CAIR
: Extract Secale Cornuiti
KENTAL : Extract Belladona
KERING : Extract Opii

Tincture
TOXIC : Kadar 10%
Tinctura Opii
Tinctura Belladona
Tinctura Digitalis
NON TOXIC : Kadar 20%
Tinctura Valeriane

Infusum
R/ Folia Piperie betle
Natrii Chlorid
Aqua
f. Infus
S garg. 4 dd

20
4
qs
200 ml

----- paraf

R/ Folia Digitalis
Aqua
Alkohol
Spirit Cinnamomi
f. Infus
S 3 dd cth II
----- paraf

15 g
900 ml
100 ml
5 ml
1000 ml

NEBULA /AEROSOL

Gas :
-dichloro difluoro methane
-trichloro monofluoro methane
-dichloro tetrafluoro methane
Nama dagang :
-Freon
-Genetron
-Isotron
-Ucon

GUTTAE

1 ml H2O ~ 1 g H2O = 20 tetes

R/ Zinci Sulfate
0,25 %
Aqua ad
10 ml
f.Steril
S 3 dd gtt II OD/OS
----- paraf

SIRUPUS
R/ Sukrose
65 %
Aqua ad
1000 ml
sirupus simplex
---- paraf

SATURATIO
R/ Acid Citric
Aqua
Spir Citri
Sir.Simplex
Natr. Bicarbonat
Aqua
Potio Riveri

2,5
25
2,5
12,5
3
55

----- paraf

Injectio / Suntik
Tujuan, Keuntungan, Kerugian
Syarat, Bentuk, Wadah

TERIMA KASIH