#50 Med42

L1 Eating
disorders ,Sleeping
disorders and
Addiction
Eating disorders
Appetite and satiety
regulation
-Hypothalamus

-Hormones ex
Ghrelin,Leptin
-Glucostatic hypothesis
Glucose
Disorders

-Feeding center (): LH

-Satiety center ():
VMH
1.Anorexia nervosa
midteens (14-18)

female>>male
-in developed
count

 #50 Med42
Etiology -genetic -low
self-esteem

-
-perfectionist
Characteristic -<
85% () -

2.Bulimia nervosa

-Starvation

anorexia (1% pop

developed count)

Starvation =

metabolic alkalosis (
)

anorexia

-
-female>male

Etiology -
Treatment -Admit

-Antidepressants

serotonin,NE,Ech
.

- self-

anorexia

esteem

Characteristic -Binge
eating




Treatment -OPD
-Antidepressant
~
anorexia

 #50 Med42
Sleeping disorders
Sleep


() ,
1/3 ,
25 ,

!!(
)

-ARAS
-Neurotransmitter
:dopamine,histamine
(antihistamine

),orexin,NE
:GABA,serotonin (
) Melatonin
pineal gland
hypothalamus

Sleep control

External Zeitgebers

Polysomnography
1.EEG=Electro Encephalo
gram --> brain
2.EMG=Electro Myo gram
--> muscle

internal -Suprachiasmatic
nucleus (SCN) anterior
hypothalamus
24
(Circadian rhythum)

3.EOG=Electro Oculo gram

-->
4.ECG=Electro Cardio gram
-->

 #50 Med42
Sleep stages ( EEG)

2.REM (Rapid eye

movement)
Sawtooth
Wave ( )
Paradoxical
sleep ,


Sleep paralysis , O2

Beta Wave
Alpha Wave
1.NREM (Non-rapid eye
movement)

, penile
erection ,

Hypnogram

1.1 stage I



Theta Wave
1.2 stage II
.
lucid

K complex,Sleep spindle
1.3 stageIII,IV


Delta Wave

sleep cycle 1
1 cycle 80100 1 4-6
cycle
Sleep problem

 #50 Med42
1.Insomnia ()

Cause

-medical condition
ex
-. ex

- ex
Treatment

-Hypnotic

REM
REM
cataplexy


hypnopompic/hypnagogic
hallucination
/
Sleep
paralysis ()

3.Parasomnia (
)
Sleep

-Sleep hygiene
()

walking,Sleep terror

,Sleep
talking,Nightmare disorder

2.Hypersomnia (
)
Cause -Narcolepsy
-->

,Sleep related bruxism

. Insomnia
hypersomnia dysomnia

Addiction

 #50 Med42
-

-

.Tolerance Withdrawal
reward pathway
Mesolimbic pathway

Physical
Psycholosical

Dopamine

Etiology -genetic -low

coping skill (

1.Substance use disorder

.) - Peer

Substance ()

Substance dependence
()
-Tolerance

-withdrawal

pressure (
~)
Treatment
-Detoxification
-Rehabilitation ex
, coping
2.Pathological gambing (
)
Etiology -.
(serotonin)
Phase winning->progressive loss
-->desperate->hopeless
Treatment
serotonin group therapy

 #50 Med42
3.Internet gaming disorder
-Male>Female

-young teenager
-asian>>US,EU