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  • Safety and Environmental Aspects: Stockholm Convention On Persistent Organic Pollutants EU

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    Aldrin is a highly lipophilic and persistent pesticide that was banned by the Stockholm Convention on Persistent Organic Pollutants and in the U.S. in 1974 due to its extreme toxicity to fish and carcinogenicity. It has low water solubility which contributes to its environmental persistence, and has an oral LD50 for rats of 39-60 mg/kg and LC50 for fish of 0.006-0.01 mg/L. Occupational exposure limits have been set at 0.25 mg/m3 over 8 hours due to its potential carcinogenicity.

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    About the aldrin drug

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    Aldrin

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    Aldrin is a highly lipophilic and persistent pesticide that was banned by the Stockholm Convention on Persistent Organic Pollutants and in the U.S. in 1974 due to its extreme toxicity to fish and carcinogenicity. It has low water solubility which contributes to its environmental persistence, and has an oral LD50 for rats of 39-60 mg/kg and LC50 for fish of 0.006-0.01 mg/L. Occupational exposure limits have been set at 0.25 mg/m3 over 8 hours due to its potential carcinogenicity.

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    9 views1 page

    Safety and Environmental Aspects: Stockholm Convention On Persistent Organic Pollutants EU

    Uploaded by

    rehrheherwhrwre
    Aldrin is a highly lipophilic and persistent pesticide that was banned by the Stockholm Convention on Persistent Organic Pollutants and in the U.S. in 1974 due to its extreme toxicity to fish and carcinogenicity. It has low water solubility which contributes to its environmental persistence, and has an oral LD50 for rats of 39-60 mg/kg and LC50 for fish of 0.006-0.01 mg/L. Occupational exposure limits have been set at 0.25 mg/m3 over 8 hours due to its potential carcinogenicity.

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    Like related polychlorinated pesticides, aldrin is highly lipophilic.

    Its solubility in water is only


    0.027 mg/L, which exacerbates its persistence in the environment. It was banned by the Stockholm
    Convention on Persistent Organic Pollutants. In the U.S., aldrin was cancelled in 1974. The
    substance is banned from use for plant protection by the EU.[6]

    Safety and environmental aspects[edit]


    Aldrin has rat LD50 of 39 to 60 mg/kg (oral in rats). For fish however, it is extremely toxic, with
    an LC50 of 0.006 0.01 for trout andbluegill.[3]
    In the US, aldrin is considered a potential occupational carcinogen by the Occupational Safety and
    Health Administration and theNational Institute for Occupational Safety and Health; these agencies
    have set an occupational exposure limit for dermal exposures at 0.25 mg/m3 over an eight-hour timeweighted average.[7] Further, an IDLH limit has been set at 25 mg/m3, based on acute toxicity data in
    humans to which subjects reacted with convulsions within 20 minutes of exposure. [8]

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