1

1
B

1
C

-1
1
-1
1
-1
1
-1
1
-1
1
-1
1
-1
1
-1
1

1.4
D

-1
-1
1
1
-1
-1
1
1
-1
-1
1
1
-1
-1
1
1

-1
-1
-1
-1
1
1
1
1
-1
-1
-1
-1
1
1
1
1

Response
-1
10
8
-1
9
-1
18
-1
14
-1
15
-1
10
-1
14
-1
12
1
18
1
11
1
16
1
10
1
24
1
12
1
15
17
1
6
6

-46
-2
4
12
-2.88 -0.13 0.25 0.75
130
+
84
Main effect -23

108
106
-1

BDD+

105
109
2

-16

58
48
-10

BC
1
-1
-1
1
1
-1
-1
1
1
-1
-1
1
1
-1
-1
1

214
2
13.4 0.13

101
113
6

106
108
1

B+
43
65
22

MediaAB
9
9
9
18
14
15
10
14
12
18
11
16
10
24
12
16
4
6

70
60
50
40
30
20
10
0
B-

AC
1
1
-1
-1
-1
-1
1
1
1
1
-1
-1
-1
-1
1
1

1
-1
1
-1
-1
1
-1
1
1
-1
1
-1
-1
1
-1
1

-24 -12
-1.5 -0.75
119
95
-12

113
101
-6

20
10
0
B-

AD

BD
1
-1
1
-1
1
-1
1
-1
-1
1
-1
1
-1
1
-1
1

CD
1
1
-1
-1
1
1
-1
-1
-1
-1
1
1
-1
-1
1
1

ABC ABD ACD BCD ABCD

1
-1
-1
-1
-1
1
1
1
1
1
-1
-1
1
1
1
-1
1
-1
1
-1
-1
1
1
1
-1
1
-1
1
1
-1
-1
-1
1
-1
1
1
-1
-1
1
1
-1
1
-1
1
-1
-1
-1
-1
-1
-1
1
1
1
-1
-1
1
-1
-1
1
1
-1
1
-1
1
-1
1
-1
-1
1
-1
-1
-1
1
1
1
-1
-1
1
1
-1
-1
1
-1
-1
1
-1
-1
-1
1
-1
1
1
1
1
1
1

-24
-1.5

-32
2
-2 0.13

119
95
-12

123
91
-16

106
108
1

8
4
-6
2
-6
0.5 0.25 -0.38 0.13 -0.38
103
111
4

105
109
2

110
104
-3

106
108
1

110
104
-3

DD+

B+

A
B
C
D

-1
0.5
0.25
60
150

1
0.25
0.125
70
175

-1
0.5
0.25
60
150

1
0.25
0.125
70
175

4.8

A
B
C
D

B+

0 1 unit
0.375
-0.125
0.1875
-0.0625
65
5
162.5
12.5

1
1
1
1.4

0.25
0.125
70
180

0 1 unit
0.375
-0.125
0.1875
-0.0625
65
5
162.5
12.5

0.25
0.125
70
180

1
1
1
1.4