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Acknowledgments

As in all endeavor's thanks go to Allah ,without whose


blessings nothings is possible.
Thanks go to Dr Ahamed Badwi for comprehensive
reviewed MCQs, in pharmacy. and pharmacy students for
being our harshest critics
Dr Yehia H. Elmelik
Riyadh

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Suspension (solid in liquid or gas dispersion):


Are two phase system consisting of finely divided solids dispersed
in liquid or gas.
Shelf life 7- 14 days
Shake the bottle before use.

Lotions:
- Are liquid suspension intended for external
application to the body.
- Ex. Calamine Lotion, Benzyl benzoate.
- Shake the bottle before use.
- Store below 25%C.
- Using preservative to avoid contamination.
- Should be labeled for external use.

Ointment:
- Are semisolid preparations intended for external use
- Ointment basses:
1. Oleaginous or hydrocarbon bases.
2. Absorption bases.
3. Emulsion bases.
4. Water soluble bases.

Methods of preparation:
1. Fusion method
2. Mechanical incorporation.
A. Using glass mortar pestle called Trituration
B. Using glass slab and spatula called as lavigation.

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Creams:
- Are semisolid preparations usually either:
1. O/w emulsion (Aqueous cr.)
2. W/o emulsion (oily cr.)

Pasts:
- Are concentrates of absorptive powder dispersed in
petrolatum or hydrophilic petrolatum.
- Are semisolid preparations intended for external use.
- Paste differs from ointment in containing a large
amount of finely powdered solid.

Tablets:
- Methods of preparation:
1. Wet granulation.
2. Dry granulation.
3. Direct compression.

- Classification of tablets:
1. Tablet for oral ingestion.
2. Tablet used in oral cavity.
3. Tablet used to prepare solution.

Tablets may be coated for number of reasons:1. To mask taste, odor, color of drug.
2. To control release of drug.
3. To protect drug from acid content of stomach.
4. To incorporate another drug and provide
sequential release.
5. To avoid incompatibility.
6. To improve appearance.

Enteric coated tablets:


Are coated and remain intact in the stomach but
give their ingredient in the intestine. E.g. ecotrin.
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Coating materials are fats fatty acidwaxes- PEG- Sugar and chocolate.

- Excipients of Tablets:
Diluents: Lactose Starch cellulose.
Binder: Starch cellulose gelatin.
Disintegrate: Starch der. Cellulose der.
Lubricant anti adherent and glidants: Magnesium
and calcium separate.
5. Coloring agents
6. Flavoring agents.
7. Sweeteners:- e.g. saccharin and aspartame.

1.
2.
3.
4.

- Processing problems:
1.
2.
3.
4.

Capping.
Lamination
Picking.
Mottling.

Capsules
- Gelatin capsule may be hard or soft.

Pharmaceutical Calculations
Systems of weight and Measures
Metric System:

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1. Units of weight:

Name of the unit


Kilogram
Gram
Milligram
Microgram

Addreviation
Kg
g
mg
ug

Relationship
1/1000 (0.001) kg
1/1000 (0.001) g
1/1000 (0.001) mg

Name of the unit


Liter
Milliliter
Micro liter

Abbreviation
L
ml
ul

Relationship
1/1000 (0.001) L
1/1000 (0.001) ml
1/1000 (0.001)m

Name of the unit

Abbreviation

Relationship

Meter
Centimeter
Millimeter

m
cm
mm

1/1000 (0.01) L
1/1000 (0.001)m

Conversion:
Exact equivalents are used for the conversion of specific
quantities in the pharmaceutical formulas and prescription
compounding
1 Mass
1 gram (g)
1 kilogram (kg)
1 grain (gr)

= 15.432 grain
= 2.240 pound
= 0.065 mg

1. Volume
1 liter (1)

= 35.2 fluid ounces


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= 0.22 gallon
2. Length
1 meter (m)
1 inch

*
*
*

= 39.37inches
= 2.54 cm

1 tea spoonful (tsp.)


= 5ml
1 table spoonful (tbsp.)
= 15ml
1 milliliter (ml)
= 16 drops (dps or gtts)

Calculation of doses:
Total amount of doses = size of dose + number of doses.
Example # 1:
How many drops would be prescribed in each dose of
liquid medicine in 15ml contained 60 doses?
1 ml = 16 drops
15ml = ?? drops 480 dps or gtts
size of dose = 240dps /60 doses = 4 dps or gtts

Example # 2:

How many doses are found in 10g, if the dose is 200mg?


Number of doses = 10g/ 0.2g
= 50 doses

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Example # 3:
How many milliliters of liquid medicines would provide
a patient with 2 table spoonful twice a day for 8 days?
Total amount = 2 15ml 2 8
= 480ml

Dosage Forms:

Iodine Solution
2% w/v
Normal Saline
0.9% w/v
Glycerol Solution 10% v/v
Potassium Permanganate Solution 0. 1% w/v
Mercurochrome Solution 2% w/v
Alcohol Solution
70%
Dextrose Solution
5%

Apparatus:
Baker, Watch glass, Measuring cylinder, Glass rod,
Balance, Mortar, Pestle, slab, Spatula.

Percentage concentration of Solution are Expressed as


follow:
1. Percent weight in weight (w/w)
EX How many gram of substance are needed to prepare
200 gram 10% w/w ?
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2. Percent weight in volume (w/v)


Ex..... How many grams of drug are needed to make 120ml
of 25% solution?

3. Percent volume in volume (v/v)


Ex. How many ml of pure alcohol needed to make 500ml
of 10% alcohol?

Examples:
1. Prepare 100 ml of 70% using 95% alcohol.

Medication questions for further study:


1. On hand: Bus Copan 20 mg/ml
Order : 5mg
You give:

2. On hand: Bus Copan tablets 200mg


Order
: 0.4g
You give:

3. On hand : Aminophylline 250 mg /10ml


: 75 mg add to 1.v Order
You give:

other concentration Expression


Molarity (m): is the expression of the moles of solute
dissolved per liter of solution. It is calculated by dividing
the moles of solute by the volume of solution in liters.

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MA = moles of solute / volume of solution in L

Ex.. How many grams of Na OH we need to prepare 0.5m


solution of NaOH(MW=40mg/mole) in 1L of H2 o?

Important Information


Over dose

)Antidote (
Protamine Sulphate

Heparin
Paracetamol
Warfarin
Morphine
Heavy metals
Poisoning by Lead, Mercury
& arsenic
Toxicity by Iron

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N Acetyl cysteine
Vitamin K
Naloxone
Dimercaprol
Penicillamine
Deferoxamine
Mesylate

Toxicity by
organophosphates
Hypercalcemia

Vitamins
Vitamin B1
Vitamin B2
Vitamin B6
Vitamin B12
Vitamin C
Vitamin K


Warfarin
Insulin
Spironolactone
ACE Inhibitor
Heparin
Tetracycline

Edetate Disodium

Generic Name
Thiamine
Riboflavin
Pyridoxine
Cyanoconlamine
Ascorbic Acid
Phytomenadione



Aspirin, Vitamin K, Phenobarbital
B- Blockers
Digoxin
Potassium Sparing Diuretics
Aspirin, Ampicillin
Antacid (Moxal )


/(- = )
+(/ = )

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Abbreviations

Abbreviation
Meaning
am
morning
aq
water
ad
right ear
as
left ear
au
each ear
bid
twice a day
Cap.
capsule
gtt
a drop
h
hour
hs
at bed time
inj
injection
nebul
a spray
non rep
do not repeat
noct
at night
no
number
ou
each eye
od
right eye
os
left eye
po
By mouth
pc
after eating
pm after
noon
evening
prn
when needed
pulv
a powder
qs
quantity
sufficient
qd
every day
qh
every hour
qid
four times day
soln
solution
stat
immediately

supp
syp

suppository
syrup
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tab

tablet

tid
tbsp
tsp

three times a day


table spoon
tea spoon

ACE
AIDS
BP
USP
CNS
G6PD
HIV
HRT
NSAID

WHO
S.N.F.

Angiotesin- converting enzyme


Acquired immune Deficiency
Syndrome
British pharmacopoeia
United State pharmacopoeia
Central Nervous System
Glucose 6- phosphate dehydrogenises
Human immune Deficiency virus.
Hormone Replacement Therapy
Non- Steroid Anti-inflammatory Drug
Trade Mark
World Health Organization
Saudi National Formulary

Ulcer Healing Drugs




:
.
. .

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. Zollinger Elisson Syndrome .3

1: H2 blocker
Generic name
* Cimetidine
* Rantidine
* Famotidine

Trade name
* Tagmet
* Zantac
* Pepsidin

Use


.( prolactin) ( Cimetidine) 1 .1

( Rantidine)

( Famotidine)
.2

. ( Cimetidine)

2: Proton pump Inhibitors


Generic name
* Omeprazole
* Lansoprazole
* Esomeprazole
* Pantoprazole
* Rapeprazole
* Misoprazole

Trade name
* Losec
* Lanzor
* Nexium
* Protium
* Pariet
* Cytotic

Use

-----------

. Losec .
Losec

Sucralfate .

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*
.
-. -

1: Bulkn Forming Laxative


:
- Bran

- Carboxy methyl cellulose


- Methyl cellulose
) ( - Mg S04

Liquid Parafin

3: Osmotic Laxative

)(Lactulose
- Sorbitol
- Glycerin

- Duphlac

4: Irritant Laxative
Trade name
Use
* Dulcolax
* Senalox -- -* -- --

Generic name
* Bisacodyl
* Senna
* Castor Oil

: )(OTC
*
A,D,E,K

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Antidiarhoeal

Generic name
* Activated Charcol
* Koalin + Bectin
* Dopramide
* Lopramide

Trade name
Use
* Eucarbon
-- -* Kapect
* Lomotil -- -* Imodium -- -:

.( Lomotil) ( Imodium) .
Metronidazole .
.
.
.

Perpetration For Hemorrhoids



1-Bismuth Oxidex Perm balsam + Zinc oxide.
.[( ] Anusol)
2- Aluminum aulate + hydro cortisone acetate + Lidocaine +
Zinc oxide.
[( ] xyloproct)
3: Herbal antihaemorrhoidal Preparation.

( Neohealar)

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Antispasmodic Drugs
Generic name
Trade name
Use
* Cisaprid
* Cisaprid --* Hyoscin
* Buscopan --* Mebeverin
* Duspatilin --* Simethicon
* Disfoatyl -- -* Peperment Oil
* --

Antiemetic

Generic name
* Metoclopramide
* Domperidone
* Meclazine

Trade name
* Primpran -* Motelium -* Navidoxine --

Use
---:

.(Antiflatuent drug) ( Simethicon)

Vitamins

Vitamin
* Vitamin A
* Vitamin B1
* Vitamin B2
* Vitamin B6
* Vitamin B12
* Vitamin C
* Vitamin D

Generic name
* Retinal
* Thiamine
* Riboflavin
* Pyridoxine
* Cyanoconlamine
* Ascorbic acid
* Cholecalciferol

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* Vitamin E
* Vitamin K

*
* Phytomenadione
:

A-D-EK .
Vit B12 .
vit k ).(warfarin

Analgesics
Analgesics
1- Non opoid analgesics
2- Opoid analgesics


* Morphine sulfate
* Acetyl salicylic acid
* Codeine phosphate
* Fentanyl citrate
) (Aspirin
* Methadone HCL
* Naloxone
*Paracetamol
* Naluphin HCL
)(panadol
* Pethidine HCL

:
.
) (.
. .
. .

N-Acetylcyctine -

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Ant migraine

Generic name
*Ergotamine
tartar ate
* Sumatriptan

Trade
name
* Cafergot

Use

* Imigran


1-Serotonin receptor blocker methysergide ,cyproheptadine
2-beta blocker: Propranolol
3-calcium channel blocker :Verapamil

Ant rhumatic

Generic name

Trade name

Use

* Diclofenac Sodium

* Voltaren Rumafin

* Piroxicam
* Diclofenac Potassium
* Indomethacin
* Ibu profen

* Feldin
* Rapidus Cataflam
* Indocid
* Brufen

-- --- --- --- --

* Meloxicam
* Tramadol
* Mefenamic acid
* Tebixucam
* Laormoxiciam
* Celecoxib
* Glucosamine

* Mobic
* Tramal
* Ponstan
* Tilcotil
* Xefo
* Celebrex
*Glucosamin
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-- --- --- --- --- --- --- --

Drugs Supress Rhumatic Process



Use

T.N
* Pencillamine

S. N Generic
name
*
Pencillamine

Drugs for Gout


) (
T.N
Use

-- --

* Zyloric
* Colchicine

Generic
name
*Allopurinol
*colchicine

:
* ) (uric acid .
* ) (Zyloric
* )(Zyloric ).(Uric acid
* Ketoprofen Ibuuprofen ,Aspirin )(N S A I D

Non Steroidal anti- inflammatory drugs
* .
* Ibuprofen Paracetamol )(O T C

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Drugs used for Neuromuscular disorder


...
*Myasthenia Gravis
Generic name
* Neostigmine
methyl sulphate
* Pyridostigmine
bromide

T.N
Use
*Neostigmine

* Mestinon

Skeletal Muscle Relaxants



Generic name
* Baclofen
* Tizandin
* Chlorzoxazone

T.N
Use
* Liordsal
* Sirdalud --* Parafon ---

Diabetes Mellitus
( ) Type(1)
( )Type (2)

:
.

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Drugs Used in Diabetes


)Diabetes Mellitus (D.M

1- Insulin
2- Non Insulin
dependent D.M
dependent DM
)(juvenile D.M
)(N.I.D.D.M


()I.D.D.M

2- (Oral hypoglycemic
1- Insulin
drugs

1-Insulin
T.N
Use
*Human R

-----

*Insulatard
* Mixtard

S.N
* Human soluble Insulin
()(Regular Insulin )
* Human isophane insulin
)(NPH
* Regular Insulin+ NPH

:
) (S.c )(Regular Insulin
) (I.V or IM .
.
) ( -.

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Oral Hypoglycemic drugs


First generation

Generic name
* Tolbutamide

T.N
*

Chlorpropamide

Use




Generic name
* Glibenclamide

T.N
* Daonil

* Gliclazide * Diamicron
* Gliclazide

Use

--- -----

* Minidiab

* Metformin Glucophage --* Metformin


* -+Rosiglitazone Avandamet
-* Rosiglitazone * Avandia
-* Repaglinide * Novonorm ----

-----

*
* Metformin
+Glinbenclamide Glucovance

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Drugs for Hypoglycemia



Generic name
* Glucagon
+Lactolose

T.N
Use
*Glucagon

:

( Simple goiter)

(Cancer thyroid)

Ant thyroid Drugs



Generic name
* Carbimazole
* Proylthioyracil

T.N
Use
* Neomercazole

* Thyrocil
-- --

Antituberculosis Drugs
T.B
Generic name
* Rifampicin

T.N
* Rifadin

* Ethambutol HCL

Use

--

* Iso- niazide

*INH

* Pyrazinamide

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--

* Rifampicin +
Izo-niazide

* Rifinah
----:
(Paracetamol)

.( INH) ( Ethambutol)

.(NSAId)


(Aspirin)

Antileprotic Drugs

Generic name
* Clofazimine

T.N
Use
* Lamprene
-- -* Dapsone

* Diaphenyl sulfone

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Antibacterial Drugs

Penicillin
1- Penicillin
1- Penicillin
Generic name

T.N

* Penicillin G
benzathin

* Retarpen

* Penicillin V
potassium

* Ospen

2- Penicillinase Resistant Penicillin's.

S.N

T.N

* Cloxacillin
Sodium

* Ultraxin
* Floxapen

* Flucloxacillin
sodium

3- Broad Spectrum Penicillin's.

Generic name
* Amoxicillin

T.N
* Amoxil

* Amoxicillin + Clavulanate

* Augmentin

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Potassium
* Ampicillin Sodium

* Penbritin

4- Antipseudomonal Penicillin's

Generic name

T.N

* Piperacillin Sodium

* Pipril

* Ticarcillin

* Timentin

Amoxicillin+ :

* Cephradin Velosef
* Cephalexin Monohydrate ketek
* Cephazolin Sodium Totacef
* Cefaodroxil Ultra

Cephalosporin's

1- First generation
Generic name

T.N

* Cephradin
* Cephalexin monohydrate
* Cephazolin Sodium
* Cefaodroxil

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* Velosef V
* Keflex

* Totacef T
* Ultra

2- Second generation
Generic name
* Cefaclor

* Ceclor

* Cefuroxime auxetil

* Zinnat

* Cefuroxime

* Zinacef

* Cefoxitim Sodium

T.N

* Mefoxin

3- Third generation
Generic name

T.N

* Cefotaxim Sodium

* Claforan

* Ceftriaxone Pentahydrate

* Fortum

* Ceftriaxone Sodium

* Rocephin

4- Fourth generation
Generic name

T.N
* Maxipime
* Suprax

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Carbapenam
Generic name

T.N
* Tienam

* Timpenem

* Meronam

* Meropenem

:
.
) (Silver salfadiazin ..

Amino glycoside

Use

Generic name

T.N
*
Gentamicin

* Gentamicin Sufate
* Tobramycin Sufate

* Nebcin
* Amikacin Sufate
* Rulid
* Neomycin
* Neomycin
* Kanamycin

*
* Streptomycin Sufate Kanamycin

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*
Streptomyc

Macrolides
Generic name

T.N

* Erythromycin

* Erythricin

* Azithriomycin

* Zithromax

* Clarithromycin

* Klacid

* Roxithromycin

* Roxamide

Use

* Spiramycin * Rovamycin

:
.( Erythromycin)
( Gentamicin)

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Clindamycin
Generic name

T.N

* Clindamycin

* Dalacin

* Clindamycin phosphate

* Dalacin

Quinolones
Generic name

T.N

* Coprofloxacin

* Ciprobay

* Ofloxacin

* Ofloxacin

* Levofloxacin

* Tavanic

* Norfloxacin

* Noroxin

* Nalidixic acid

* Nalidram

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Other Antibiotics
Generic name

T.N

* Spectinomycin
* Togomycin
* Svancomycin
* Vancocin
* Sulfonamides
*Septrin
* Sulfamethoxazole +
Trimethoprim

* Bactrim

* Nitrofurantoin

* Furadantin

Antifungal Drugs

T.N

Generic name
Amphtericin B*

* Fungi zone

* Nystatin

* Mycostatin

* Fluconazole

* Diflucan

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* Itraconazole

* Sporanox

* Ketoconazole

* Nizoral

* Miconazole

* Daktarin

* Grisofulvin

* Grizovin

* Terbinafin

* Lamisil

* Clotrimazole

* Canesten

:
.(Vaginal thrush)
Clotrimazole Miconazole Ketoconazole Nystatin
:( Mouth thrush)
Nystatin Miconazole Clotrimazole
:(Skin scalp)
Grisofulvin Ketoconazole Nystatin Clotrimazole Terbinafine

Antiviral Drugs

Generic name

T.N

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Acyclovir *

* Zovirax

* Zidovudine

* Retrovir

* Lamivudine

* Zeffix

* Zalcitabine

* Hivld

:
(* HID) Human Immunodeficiency Virus
( )
:( Herpes simplex)( Aciclovirus)
.( H S V encephalitis)
:(Genital Herpes Infections)
( Zidovudine)

Antihelmintics

Generic name
*Menendazole

T.N
* Vermox

* Levamizole

* Ketrax

* Niclosamide

* Yomesan

* Pranziquantel

* Biltracide

* Albendazole

* Zentel

:
(Schist soma Taenia)

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Pranziquantel Niclosamide
:( Ascaris Ankylostoma)
(Mebendazole)
.
Albendazole Mebendazole Hydatid Disease)

Antiprotozoal Drugs

Generic name
* Chloroqyine Phosphate

T.N
* Navaquine

Use
Anti malarial

* Anti malarial * Antimalarial


* Mefloquine HCL

* Mephaquin --

--

* Primaquine Phosphate

* Primaquine --

--

* Quinine

* Quinine --

--

* Pyrimethamine
Sulfadoxine

* Fansidar

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* Metronidazole

* Flagyl

* Diloxanide Furoate

* Furamide

Amoebicides
Trichomoniasis
Antigiardia

* Pentacarinat
* Pentacarinat
* For
Peneumocytosis
Pneumonia

.( Metronidazole) :

Corticosteroids
( )

Generic name
* Fludrocortisone acetate

T.N
* Florinef

* Prednisolone

* Prednisolone

* Dexamethasone

* Oradexon

* Hydrocortisone

* Hydrocorton
* Solucortif

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* Methylprednisolone

* Depomedrol
* Solumedrol

.(Hydrocortisone)(Betamethasone) :

Topical Corticosteroids Drugs acting on Skin

Drugs Affecting Cardio- Vascular System


1-Antihypertensive

A/ Diuretics
Loop Diuretics
Generic name
* Furosemide

T.N
Use
* Lazix

* Edecrin

* Ethacrinic

* Edecrin -Sodium
-Thiazide & Related
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---

S. N
* Chlorthiazide

T.N
Use
* Hygroton

* Esderex

* Hydrochlorothiazide
* Indopamid

* Natrilix

. K Ca++ Na+ :

Potassium sparing diuretics


Generic name
* Spironolacton

T.N
Use
* Aldactone

* Moodurtic

* Amialoride
* Triamterine

* Dyazid

.(K+)( Hyperkalemia) :

Osmotic Diuretics
Generic name
* Mannitol

T.N
Use
* Mannitol

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Ca++ channel Blocker

Angina
()
Generic name
* Diltiazem

T.N
Use
* Dilzem

* Amlor
--* Insuptin
--* Adalat
--* Plendil
--* Micard
---

* Amilodipine HCL
* Verapamil
* Nifedipine
* Flodipin
* Nicardipine

:
(Ca++ channel Blocker)
Verapamil .

D Anti- Adrenergics

1- ALPHA Adrenergic blockers


Generic name
T.N
Use
* Prazosin HCL
* Minipress

2- BETA- blokers
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S. N
* Atenolol

T.N
Use
* Tenormin

* Bisoprolol

* Concor --

---

* Propranolol

* Indral

:
( BETA- blokers)
.( ) glaucoma Angina
B1 bloker Atenolol
B bloker Propranlol

3-ALPHA&BETAbloker
Generic name
* Carvedilol

4- Centrally acting
(Alpha2- agonist)
Generic name
* Methyldopa

T.N
Use
* Dilatrend

T.N
Use
* Aldomet

* Clonidine

* Catapress --

--

* Moxonidin

* Physiotens --

39
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:
.(asthma)
. Nor- adrenali
Methy Idopa

. Methy Idopa

Antiarraythmic Drugs

Generic name
* Aciodaron
* Quinidin
* Disopyramid
* Mexiletine
* Lidocain


T.N
Use
* Cordaron

* Quinidin
--* Rythmodan
--* Mexitil --* Xylocain --

40
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--

Congestive Heart Failure


Generic name
* Digoxin

T.N
Use
* Lanoxin

Drugs used in angina


Generic name
* Isosorbiddinitrate
* Nitroglycerin
* Glyceryl Trinitrat

T.N
Use
* Isordil

* Nitroderm
--* Augised
---

Anticoagulant drugs
( )

Generic name
* Heparin

T.N
Use
* Heparin

* Warfarin

* Coumadine --

--

* Protamine

* Protam --

--

( Antidote) :
.k(Vit K)(Warfarin)
41
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Ant platelet Drugs


T.N
Use
* Persauten

* Plavix
---* Aspirin --

Generic name
* Dipyridamlo
* Clopidogrel
* Aspiril 75

Fibrinolytic

T.N
Use
* Kabikinase

Generic name
* Streptokinase

Drugs used for Hemorrhage


Use

T.N

Generic name

42
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Ethamsylate*

* Dicycone

* Phytomenadione

* Konadion --

--

* Acetamenaphtone

* Vit k --

--

* Tranedamic acid * Cyclokapron

Lipid Lowering Drugs


S.N
*Cholestyramine

T.N
Use
* Questran

* Simvastain

* Zocor --

--

* Gemfibrozil

* Lopid --

--

* Pravastain

* Lipostat --

--

* Atorvastatin

* Lipitor

Antihistamines

1- Non Sedating Antihistamines

Generic name
* Cetrizine
* Loratadine

T.N
Use
* Zyrtec

* Claritne --

* Fexofenadine

* Telfast
--

43
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--


2- Sedating Antihistamines
Generic name
T.N
Use
* Chlorpheniramine
* Histop

-* Promethazine HCL
* Phenargen H2- antagonist Celecoxib, Loratadine, histadine:

Sex Hormones

1- Estrogens for Hormone Replacement Therapy


Generic name
* Estradiol valerate

T.N

* Ethinyl estradiol

Use
*

*
---

2- Progestogens

Generic name
* Dudrogestrone

T.N
Use
* Duphaston

* Norethisterone

* Primolut N

--

--

* Medroxy progestrone

* Provera

--

--

* Hydroxyprogestrone * Prolutone depot

--

--

44
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* Megestrol acetate

:( Megestrol acetate) Malignant)

.(


3- Androgens
S.N
Testosterone

T.N
*

4- Hormone antagonists for malignant disease


Generic name
* Tamoxifen
* Flutamide
* Amionglutethimde

T.N
Use
* Nolvadex

*
--*
---

Drugs for genitourinary disorders



Generic name
* Ditigmine

* Flavoxate

T.N
* Ubretid

Use
*For Urinary Retention

*For Urinary Frequency
* Urispas
And Incontinence

-45

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--

Endocrine Drugs

Generic name
T.N
* Bromocriptine * Bromocriptin
* Danazol

Use
*Dopamine
Receptor

* Danol
*Treatment of
endometriasis

Bronchodilators

Generic name
T.N
Use
* Salbutamol * Ventolin

* Ipratropium * Atrovent
-- -* Theopylline * Quibron

--

--

* Aminophylline * Euphyllin

--

--

46
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* Beclomethasone * Becotide

--

--

* Budesonide * Palmicort

--

--

* Sodium cromoglycate

* Intal

--

--

* Fluticasone Propionate +
Salmetrlo

* Seretide

--

--

Cough Preparation

1- Cough Suppressant
Generic name
* Dextromethorphan

T.N
* Kafosed

Use


T.N
* Diphenhydramine HCL

* Exylin

* Bromohexine

* Acetyl cistein

1- Expectronta
Use

----

--

--

--

--

--

Ambroxol HCL * Ambroxol


Guaifenesin

3- Decongestants
3- Generic name

*
Guaifenesin

T.N

47
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Use

* Pseudo ephedrine

* Actifed

Malignant disease and Immunosuppressant

Cytotoxic Drugs

1- Alkyl ting Drugs
Generic name
* Busulfan

T.N
* Myleran

* Chlorambucil

* Leukeran

--

--

*
Cyclophosphamide

* Endoxan

--

--

* Mitoxana

--

--

* Alkeran

--

--

Use

* Ifosfamide
* Melphalan

2- Cytotoxic Antibiotics.
T.N
* Bleomycin

* Daunorubicin HCL

Use

-----

* Doxorubicin HCL

--

--

* Mitomycin

--

--

* Dactinomycin
* Mitoxantrone

*
*

---

---

48
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3- Antimetabbolites.
Generic name
* Cytarabine

T.N
* Cyctosar

Use

* Methotrexate
* Methorexate
* Fluorouracil
* Effuddix
* Mercaptopurine
* Puri-nethol


4- Other antineoplastic Drugs
Generic name
T.N
* Cisplatin

Use

* Carboplatin

--

--

* Lomustin

--

--

* Asparaginase
* Hydroxurea

*
*

--

--

---

---

* Procarbazine

Drugs affecting the Immune Response



49
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1- Immunosuppressants
Generic name
* Cyclosporin

T.N
* Neoral

Use

* Azathioprine

* Imuran

--

--


2- Immunosuppressants
Generic name
T.N
* Interferon alpha
* Interferon Beta

*
*

Use

--

--

Methotrexate, Azathioprine, Cyclosporin :


.(Immunosuppressants)

Blood Anemia's and Some There blood disorders



1- Iron:
Ferrous Salt, Ferrous Saulfate, folic acid Iron dextran
:
.
.
.
-
.

50
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Generic name
* Cynocoblamine

T.N
* Betolvex

* Folic acid

* Folic acid

Use

--

--

2- Drugs used in Megaloblastic Anemia:

3- Drugs used in Renal Anemia:


S.N
T.N
Use

* * Epoetin
Eyrythropoietin(Epoetin)
:
.( Leucopenia)
-
-

Fluids and Electrolytes


.

1- Oral electrolytes:
Generic name
* Potassium chloride

T.N
*

* Sodium bicarbonate

* Oral rehydration salt(ORS)


* Polystyrene Sulphonate resins

*
*

51
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2- Intravenous Solutions and electrolytes:


S.N

* Sodium
*
* Dextrose

* Ringer solution

* Sodium acetate

* Potassium acetate

* Potassium phosphate

* Ammonium chloride

* Sterile water

* Sodium bicarbonate

3- Plasma and plasma Substitutes


S.N
* Human albumin solution

T.N
*

* Dextran

* Human fibrinogen

* Hydroxy ethyl starch

52
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:
. ( Intravenous Nutrition)

* ) ( Amino acid Mixture

* Fate emulsion

* Multivitamins infusion (Vita A, B2,


B12,B6,C,D, E, Folic acid)

* Elements

(Zinc, manganese, chromium)

Minerals
1- Ca++,Mg++,Phosphorous:

Generic name
* Calcium gluconate

T.N
*

* Magnesium

* Phosphate salt

* Pure aluminum

* Calcium Carbonate

53
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2- Zinc:
T.N
*

Generic name
* Zinc sulfate

:
) (Hypokalemia
) (Hypercalcemia .
) (ORS : + + +
.

Mydriatics
Anticholinergicas

T.N

Generic name

* Atropine Sulfate

* Cyclopentolate HCL

* Tropic amide

* Naphazoline HCL

* Phenyl ephrine HCL

54
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Treatment of Glaucoma
( )

Generic name
* Pilocarpine
* Timolol maleate
* Timolol +
Dorzolamide

T.N
Use
* Proocarpine *

* Timoptol
*
* Cosopt
* Trusopt

--

--

* Xalatan

--

--

* Betogen

--

--

--

--

* Dorzolamide
* Latanoprost
* Levobunolol HCL

:
:( Tear Deficiency) /
* Artificial eye tear
* Liquid Parafin
:( Diagnostic Preparation) /
* Fluorescein Sodium
* Rose Bengal
( Diagnostic)Acetazolamide /
( )/

55
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Drugs acting on the Ear


Anti-infective

T.N
*

Generic name
* Chlorampheniclo

* Clotrimazole

* Gentamicin Sulfate+
Betamethasone

*
* Polymyain B sulfate + Neamycin
sulfate+ hydro cortisone.

Mouth wash

* )Chlorhexidine gluconate (Chlorasept

Preparations Eczema and Psoriasis


56
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1- TOPICAL PREPARATIONS
...........
* Coal tar
* Dithranol
* Calcipotriolene (Diavonex)
2- ORAL RETINOIDS FOR PSORIASIS

* Acitretin (Neotigason)

Preparation for Acne And Hirsutism


Generic name
* Azelaic acid

T.N

Use
*

* Benzoyl peroxide
* Clindamycin or
erythromycin

*
*
* Retina

* Tretinoin
*
* Isotretinoin

* Regain
* Menoxidil

Drugs Acting on Central Nervous System


Generic name
* Diazepam
* Lorazepam
* Midazolam

2- Anxiolytics
T.N
Use
* Valium
* Antivan -*

57
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Dormicum
* Alprazolam

-* xanx

:
.Am barbital( Barbiturates)
.OTC ( Diazepam)
.

Antidepressant Drugs

Generic name
Amitriptyline*

T.N
Use
* Triptizol

* Clomipramine HCL * Anafranil


--* Imipramine HCL
* Tofranil
--* Fluoxetine
* Prozac
--* Paroxetine
* Seroxat
---

58
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Antiparkisonism

Generic name
Carbidopa*

T.N
Use
* Sinemet

* Amantadine HCL * Symmetrel


--* Selegline * Selegline
---

Antiepileptics

Generic name
Carbamazepine*

* Phenobarbital
* Pheytoin sodium
* Sodium Valproate
* Clonazepam

T.N
Use
* Tegretol

* Luminal
--* Epantutin
--* Depakin
--* Revotril
--:

* Rifampin, Phenytoin, Carnamazepine


* Lorazepam

59
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Drugs used in Nausea and Vertigo


Generic name
Metoclopramide HCL*

* Betahistine
dihydrochloride

T.N
Use
* premperan

* Betaserc
*

* Dimenhydrinate

Anesthesia

1- Local Anesthesia
Generic name
* Lidocaine

Use

-----

* Mepivacaine
* Bupivacaine

--

--

* Ropivacaine

--

--

* Ethyl chloride

60
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2- Isoflurane Anesthesia
Use

Generic name
* Isoflurane

* Halothane
--

--

--

--

* Sevoflurane

3- Intravenous Anesthesia
Generic name
* Thiopental

Use

* Ketamine

--

--

* Propofol

--

--


Muscle Relaxant
Generic name
T.N
Use
* Atracurium bromide * Tracrium

* Pancuronium bromide * Pavulon

* Vecuronium bromide * Norcuron

61
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- :
)(
)(
)(
)(
- :
)( Isosorbid
)( Metronidazole
)( Amoxacillin
)(
- ) (OTC:
)(
)(
)(
)( &
-
)( Aspirin
)( Digitoxin
)( Hydrochlorothiazide
)( Erythromycin
- .

)( Aspirin
)( Ibuprofen
)( Ketoprofen
)( Celecoxib
- )(NSAIDs
)( Aspirin
)( Ibuprofen
)( Ketoprofen
)( Dexamethasone
-
)( Carbamazepine
)( Phenytoin
62
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)( Phenobarbital
)(
-
)( Ampicillin
)( Paracetamol
)( Phenytoin
)( Cyclophosphamide
- )(Potassium sparing diuretics
)(
)(
)(
)( &
- )(A
)( Thiamine
)( Cyanocobalamine
)( Cholecalciferol
)( Retinol
-
)( Phenobarbital
)( Aspirin
)( Digitoxin
)( Cimetidine
-
)( Phenytoin
)( Rifampin
)( Carbamazepine
)(
- )(H2 receptor antagonist
)( Histadine
)( Loratadine
)( Celecoxib
)( Rantidine
- )(Lorazepam
)(
)(
)(
)( &
63
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- )(Rantidine
)( H1 receptor antagonist
)( Loop diuretic
)( B1 receptor antagonist
)( H2 receptor antagonist
- ) (B12 :
)(
)(
)(
)(
-
)( Cyclosporin
)( Metotrexate
)( Azathioprine
)(
- ) (Nitroglycerin :
)(
)(
)(
)(
-
)( Heparin
)( Warfarin
)( Gliclazide
)(
- .
)(
)(
)(
)(

64
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- )(
)( Chlormphenicol
)( Dexamethasone
)( Atropine
)( Pilocarpine
(Leucopenia 22
)(
)(
)(
)(
-
)( Allopurinol
)( Chlorpromazine
)( Colchicine
)( &
- )
)( Chlormphenicol
)( Amoxacillin
)( Aspirin
)( Aciclovir
-
)( Ampicillin
)( Amoxacillin
)( Benzylpenicillin
)( Augmentin
- )(
)( Aspirin
)( Hydrocortisone
)( Prednisolone
)( &
-
)( Alcohol
)( Paracetamol
)( Halothane
)(
-
)( Paracetamol
65
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)( Amoxicillin
)( Cephalexin
)( Aspirin

-
)( Aspirin
)( Phenytoin
)( Prednisolone
)( Rifampin
-
)( Noradrenaline
)( Captopril
)( Verapamil
)( &
- ) (
)( Aspirin
)( Halothane
)( Hydrochlorothiazide
)( Verapamil
- )
)(
)(
)(
)(
-
)(
)(
)(
)(
-
)(
)(
)(
)(

66
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- ) (Acyclovir :
)( HSV encephalitis
)( Genital herpes infections
)( Headache
)( &

- ) (Morphine
)( Captopril
)( Methadone
)( Codeine
)( Naloxone
- ) (q.i.d.
)(
)(
)(
)(
- ) (t.i.d.
)(
)(
)(
)(
- ) (Augmentin 250 mg Tablets
.
)(
)(
)(
)(
-
)( Aspirin
)( Paracetamol
)( Timolol
)( Activated charcoal
- /

)( //
67
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)( //
)( //
)( //
- ) ( .

) ( ) ( .

)(
)(
)(
)(
-

)(
)(
)(
)(
-
.
)(
)(
)(
)(
- ) (Prozac
)( Verapamil
)( Timolol
)( Omperazole
)( Fluoxetine
- ) (Flagyl
)( Mebendazole
)( Amoxicillin
)( Phenytoin
)( Metronidazole
- ) (g/dl
)(
)(
68
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)( -
)( -
-
)( -
)( -
)( -
)( -
- :
)(
)(
)(
)(
- :
)(
)(
)( -
) (
- ) (Hypercalcemia
)(
)(
)(
)(
- ) (Glibenclamide
) (Glipizide
)(
)(
)(
)(
-
)( Aspirin
)( Salbutamol
)( Diclofenac
)( Paracetamol
-
)( Paracetamol
69
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)( Salbutamol
)( Ibuprofen
)( Diltiazem
- ) (Atenolol
)( - Blockers
)( 2 - Blockers
)( - Blockers
)( 1 - Blockers
-
)( 20 meq/L
)( 1 meq/L
)( 50 meq/L
)( 3.5 5 meq/L

- )(
)(
)(
)(
)(
- )(

)(
)(
)(
)(
-
)( Morphine
)( Hypnotics
)( Pethidine
)(
- ) (H.I.V.
)( Prednisolone
)( Verapamil
)( Diltiazem
)( Zidovudine

70
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-
)( Composition
)( Active ingredient
)( Batch number
)( Precautions
- ) (Diclofenac 50 mg
)(
)(
)(
)(
- ) (Prednisolone :
3 days t.i.d. 1
3 days b.i.d. 1
3 days q.d. 1
)(
)(
)(
)(
- ) .(Neostigmine
)(
)(
)(
)(
- :
)(
)(
)(
)(
- ) (Ganciclovir :
)(
)(
)(
)(
- ) (OTC :
)(
)(
)(
71
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) (

- ) (OTC :
)( Ibuprofen
)( Diazepam
)( Paracetamol
)( &
- ) (OTC :
)( Tegretol
)( Augmentin
)( Valium
)(
- )(Giardiasis

)( Amoxicillin
)( Ampicillin
)( Diosmin
)( Metronidazole

- ) (Warfarin
)( Aspirin
)( Vitamin E
)( Vitamin D
)( Vitamin K
-
)(
)(
)(
)(
- .

)(
)(
)(
)(

72
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-
)(
)( )(
)( )(
)(
- :
)(
)(
)( ) (
)( ) (
- ) (Urea :
)(
)(
)(
)( &
-
)( Captopril
)( Enalapril
)( Atenolol
)( Methyl dopa

- :
)(
)(
)(
)(
- ) (Tetracycline
)( H 2 - Blockers
)( - Blockers
)( - Blockers
)( Antibiotics
- ) (Hypertension
)( Diamicron
)( Buscopan
)( Flagyl
73
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Inderal

( )

( Propranolol) -
- Agonist ()
1- Blockers ()
- Agonists ()
- Blockers ()
( Spironolactone) -
Antibiotics ()
Antihistamines ()
Sedatives ()
Diuretics ()
( Spironolactone) -
Thiazide diuretics ()
Osmotic diuretics ()
Loop diuretics ()
Potassium sparing diuretics ()
( B1) -
Retinol ()
Ascorbic acid ()
Phytomenadione ()
Thiamine ()

( B2) -
Retinol ()
Ascorbic acid ()
Phytomenadione ()
Riboflavin ()
( K) -
Retinol ()
Ascorbic acid ()
Niacin ()
Phytomenadione ()
-
)(
74
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)(
)(
)(
- ) (Capotine
)( Enalapril
)( Verapamil
)( Atenolol
)( Captopril
-
)( Zocor
)( Zovirax
)( Zaditine
)( Zidovudine
- ) (ORS
)(
)(
)(
)(
- ) (ORS
)(
)(
)(
)(

- ) (Rifampicin
)(
)(
)(
)(
- ) (Rifampicin
)(
)(
)(
)(

75
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- ) (q.i.d.
)( /
)(
)(
)(
- ) (Acyclovir :
)(
)(
)(
)(
- ) (Vitamin C
)( Niacin
)( Riboflavin
)( Phytomenadione
)( Ascorbic acid
- ) (Ascariasis
)( Metronidazole
)( Verapamil
)( Paracetamol
)( Mebenidazole
- %
)( )(SC
)( )(IM
)(
)( )(IV

- )(Hepatitis B

)(
) (
)(
) (
-
)( A & D
) ( A & C
76
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)( E & K
)( &
-
)( A & C
) ( D & K
)( B & D
) ( B & C
- ) (Paracetamol
)(
)(
)(
)(
- ) (Paracetamol

)(
)(
)(
)(
- ) (Barium sulfate:
)(
)(
)(
)(
- :
)(
)(
)(
)(

- ) (Captopril
)(
)(
)(
)(

77
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- ) ( ) (Captopril

)(
)(
)(
)(
- ) ( ) (Captopril

)(
)(
)(
)(
- :
)( Aspirin
)( Captopril
)( Loratadine
)( Activated charcoal
- :
)(
)(
)(
)(
- ) (Type 2
)( Anaglesics
)( Insulin
)( NSAIDs
)( Sulfonylurea
- ) (Type 1
)( Anaglesics
)( Sulfonylurea
)( NSAIDs
)( Insulin

- ) (Theophylline :
)(
)(
78
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)(
)(
-
Anaglesics ()
Sulfonylurea ()
NSAIDs ()
Insulin ()
-
Paracetamol ()
Amoxicillin ()
Cephalexin ()
Ciprofloxacillin ()
( Cefaclor) -
Thiazide diuretics ()
Penicillins ()
Potassium sparing diuretics ()
Cephalosporines ()
( Cefaclor) ( Cephalosporines) -

79
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)(

)(
)(
)(
- ) (Voltaren
)( Aspirin
)( Diosmin
)( Piroxicam
)( Diclofenac
- ) (Voltaren
)(
)(
)(
)(

80
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- ) (Zantac
)( Famotidine
)( Cimetidine
)( Rantidol
)( Ranitidine
- ) (Zantac
)(
)(
)(
)( &
-
)( Indometacin
)( Aspirin
)( Ibuprofen
)( Paracetamol
-
)( Tetracycline
)( Gentamycin
)( Ampicillin
)( &
- ) (Sumatriptan
)(
)(
)(
)(
- ) (Nitrofurantoin
)(
)(
)(
)(
- ) (Cimitidine
)(
)(
)(
)(
81
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(Ventolin) -
Aspirin ()
Cimetidine ()
Diclofenac ()
Salbutamol ()
( Ventolin) -
)(
)(
)(
)(
) ( -
Aspirin ()
Hydrochlorothiazide ()
Furosemide ()
ORS ()
-
Rifampicin ()
Ethambutol ()
Isoniazide ()
)(
Thyroid ) -
( deficiency
Aspirin ()
Carbimazole ()
Radioactive iodine ()
Levothyroxine sodium ()
Thyroid ) -
( deficiency
Aspirin ()
Carbimazole ()
Radioactive iodine ()
Thyroxine sodium ()
Thyroid ) -
( deficiency
Aspirin ()
Carbimazole ()
Radioactive iodine ()
82
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Liothyronine

( )

Thyroid ) -
( deficiency
Aspirin ()
Carbimazole ()
Radioactive iodine ()
Triiodothyronine ()
( Thyroid hormones) -
Carbimazole ()
Propylthiouracil ()
Radioactive iodine ()
)(
( Thyroid hormones) -
Levothyroxine sodium ()
Iodine ()
Radioactive iodine ()
) ( &
( Thyrotoxicosis) -
Levothyroxine sodium ()
Iodine ()
Radioactive iodine ()
) ( &
( Gliclazide) -
)(
)(
)(
)(
( Gliclazide) -
Ventolin ()
Amoxil ()
Minidiab ()
Diamicron ()

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(Nifedipine) -
Tenormin ()
Ateno ()
Ventolin ()
Adalat ()

( Augmentin) -
Amoxicillin / Paracetamol ()
Ampicillin / Potassium clavulanate ()
Benzylpenicillin / Potassium clavulanate ()
Amoxicillin / Potassium clavulanate ()
( Co-trimoxazole) -
Trimethoprim ()
Sulfamethoxazole ()
Salbutamol ()
Trimethoprim / Sulfamethoxazole ()
( Aminoglycosides) -
Amikacin ()
Neomycin ()
Streptomycin ()
)(
: -
Tablets ()
Capsules ()
Suspensions ()
)(
: -
Tablets ()
Powders ()
Suppsitories ()
Solutions ()
: -
Tablets ()
Powders ()
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Suppsitories
&

)D
(
( )

( Clarithromycin) -
Ventolin ()
Amoxil ()
Vibramycin ()
Klacid ()

( Heparin) ( Antidote) -
Warfarin ()
Aspirin ()
Phenindione ()
Protamine sulfate ()
( Vitamin B 6) -
Niacin ()
Riboflavin ()
Thiamine ()
Pyridoxine ()
( Acetazolamide) -
)(
)(
)(
)(
( Acetazolamide) -
Lasix ()
Bumex ()
Aldactone ()
Diamox ()
( Susp.) -
)(
)(
)(
)(

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- ) (Sol.
)(
)(
)(
)(
- ) (Syp.
)(
)(
)(
)(

- ) (Supp.
)(
)(
)(
)(
- ) (Oint.
)(
)(
)(
)(
- ) (Drop
)(
)(
)(
)(
- ) (Eye drops
)(
)(
)( &
)(
- ) (Ear drops
)(
)(
)(
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) (

- ) (Nasal drops
)(
)(
)(
)(
- ) (Aspirin
)(
)(
)( ) ( )(Hemophilia
)( &

- ) (Amoxil
)( Amoxicillin / Potassium clavulanate
)( Ampicillin
)( Flucloxacillin
)( Amoxicillin
- ) (Bid
)(
)(
)(
)(
- ) (Amp.
)(
)(
)(
)(
- ) (IV
)(
)(
)(
)(
- ) (IM
)(
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)(
)(
)(
- ) (SC
)(
)(
)(
)(
- ) (sos
)(
)(
)(
)(

- ) (Dextrose 5 %
)(
)(
)(
)(
- ) (Sodium chloride 0.9 %
)(
)(
)(
)(
- ) (Claritine
)( Histadine
)( Adrenaline
)( Chorpheniramine
)( Loratadine
- ) ( ) (Claritine
)(
)(
)(
)(

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- ) (Aspirin
)( Acetylbutyric acid
)( Paracetamol
)( Mefenamic acid
)( Acetylsalcylic acid
-
)(
)(
)(
)(
- ) (Metoclopramide
)(
)(
)(
)(

- ) (Metoclopramide
)( Motinorm
)( Motilium
)( Amoxil
)( Primperan
-
)( Diclofenac
)( Paracetamol
)( Ibuprofen
)( Glycerin suppositories
-
)( Amoxil suspension
)( Voltaren tablets
)( Ventolin syrup
)( Duphlac syrup
-
)( Aldactone
)( ORS
)( Diamicron
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Dulcolax

( )

-
Ibuprofen ()
Diclofenac ()
Indometacin ()
)(
( Nizoral) -
Amoxicillin ()
Miconazole ()
Fluconazole ()
Ketoconazole ()
( Glucophage) -
Glibenclamide ()
Tolbutamide ()
Gliclazide ()
Metformin ()

( Buscopan) ( Generic name) -


Atropine ()
Pilocarpine ()
Atenolol ()
Hyoscine (Scopolamine) ()
( Allopurinol) ( Trade name) -
Profenid ()
Ketofan ()
Voltaren ()
Zyloric ()
( Cephalexin) ( Trade name) -
Duricef ()
Velosef ()
Amoxil ()
Keflex ()
( Captopril) ( Trade name) -
Tenormin ()
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)( Adalat
)( Lasix
)( Capoten
- ) (Penicillins
)( Amoxicillin
)( Ampicillin
)( Flucloxacillin
)(
- ) (G.I.T.
)( Gastroincubation time
)( Stomach
)( Urinary tract
)( Gastrointestinal tract
- ) (T. B.
)( Typhoid
)( Taenia saginata
)( Paratyphoid fever
)( Tuberculosis

-
)(
)(
)(
)(
- ) (Lasix
)( Captopril
)( Atenolol
)( Hydrochlorothiazide
)( Furosemide
- ) (Lasix :
)(
)(
)(
)(

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- ) (Simvastatin:
)(
)(
)(
)(
- ) (Simvastatin
)( Lipitor
)( Mevacor
)( Amoxil
)( Zocor
- ) (Tetracyclines

)( Chlortetracycline
)( Doxycycline
)( Ninocycline
) ( &
- ) (Questran
)( Niacin
)( Atrovastatin
)( Simvastatin
)( Cholestyramine A

- ) (Cholestyramine A
)(
)(
)(
)(
- ) (Aldomet
)( Atenolol
)( Verapamil
)( Captopril
)( Methyl dopa
- ) (Tenormin
)( Cholestyramine A
)( Captopril
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)( Verapamil
)( Atenolol
- ) (Ciprobay
)( Aspirin
)( Ampicillin
)( Amoxicillin
)( Ciprofloxacin
- ) (Zovirax
)( Oxytetracycline
)( Interferon
)( Zidovudine
)( Acyclovir
- ) (Brufen
)( Mefenamic acid
)( Diclofenac
)( Ketoprofen
)( Ibuprofen
- ) (Daonil
)( Paracetamol
)( Gliclazide
)( Metformin
)( Glipenclamide

-
)(
)(
)( -
)( -
-
)( -
)(
)(
)(
-
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Martindale ()
British national formulary ()
Middle east medical index ()
)(
( First generation) -
( Cephalosporines)
Cephalexin ()
Cefadroxil ()
Cefazolin ()
)(
( Second generation) -
( Cephalosporines)
Cefaclor ()
Cefuroxime ()
Cefoxitin ()
)(
( Third generation) -
( Cephalosporines)
Cefoperazone ()
Cefotaxime ()
Cefixime ()
)(
( NSAIDs) -
Non-steroidal inflammatory drugs ()
Steroidal inflammatory drugs ()
Non-steroidal inflammatory hormones ()
Non-steroidal anti-inflammatory drugs ()
:( Metformin) -
)(
)(
)(
)(
:( Aspirin) -
)(
)(
)(
)(
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-
Paracetamol ()
Ibuprofen ()
Heparin ()
Diltiazem ()
Grand mal ) -
( epilepsy
Atenolol ()
Heparin ()
Diclofenac ()
Phenytoin ()
( Petit mal epilepsy) -
Atenolol ()
Heparin ()
Diclofenac ()
Ethosuximide ()
-
Excretion rate ()
Absorption rate ()
Birth rate ()
Death rate ()
( Cefaclor) ( Cephalosporines) -
)(
)(
)(
)(

( Tetracyclines) -
Chlortetracycline ()
Tetracycline ()
Doxycycline ()
Clindamycin ()
-
Diloxanide Furoate ()
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)( Iodoquinol
)( Metronidazole
)( Gentamicin
- :
)(
)(
)(
)(
-
)( Acyclovir
)( Interferons
)( Amantadine
)(
- ) (Inderal tablets
)( .
)(
)(
)(
)(
-
)( Gentamycin
)( Tetracycline
)( Oxytetracycline
)(
-
)( Aldosterone
)( Insulin
)( Paracetamol
)( Finasteride

- :
)( )(Cows
)( )(Pigs
)( )Escherichia coli (E. coli
)(

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- ) (Tetracycline :
)(
)(
)(
)(
- :
)(
)(
)(
)( &
- ) & Olive oil, ASA
(Water:
)( Solution
)( Elixir
)( Suspension
)( Emulsion
- :
)( IM injection
)( ID injection
)( SC injection
)( IV injection
- ) (NaCl ) Dextrose 5 % half normal saline, D5 1/2
:(NS
)( 1.8 %
)( 0.9 %
)( 0.225 %
)( 0.45 %
- ) (Simvastatin ) (FDA ) (Pregnancy Category x :
)(
)(
)(
)(

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:( Digoxin) -
IV Normal Saline ()
Digitoxin ()
Activated Charcoal ()
Digibind ()
:( Intra-thecal injection ) -
)(
)(
)(
)(
:( Dextrose) -
Phenytoin ()
Cefazolin ()
Ceftriaxone ()
Insulin ()
:( Drug-Drug interactions) -
Enzyme induction ()
Formation of unabsorbed complex ()
Plasma protein displacement ()
)(
:(Natural emulsifying agent) -
Lactose ()
Polysorbate ()
Sorbitol ()
Acacia ()
: -
2 - 3 ()
4 - 6 ( )
> 8 ()
6 - 8 ( )
:( 1 grain) -
50 g ()
10 g ()
0.60 g ()
0.065 g ()

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- ) 5 %
(W/W
)(
)(
)(
)(
- )( )( :
)( 10 mg
)( 30 mg
)( 300 mg
)( 0.03 mg
- ) (Roaccutance ):(Advanced Acne
)(
)(
)(
)(
- )(QOD
)( Every four days
)( Four times a day
)( Every day
)( Every other day
- ) (Cerivastatin :
)(
)(
)(
)(
- ) (Cytotec :
)(
)(
)(
)(
- ) (Ibuprofen:
)( 800 mg
)( 3000 mg
)( 1600 mg
)( 3200 mg

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-
:
)(
)(
)(
)(
- )(NSAIDs
)( Tilcotil
)( Ibuprofen
)( Naproxen
)( Parafon
- ) (Amiloride ) .(Captopril
)( Hypercalcemia
)( Hyponatremia
)( Hypertension
)( Hyperkalemia
- ):(Cefuroxime
)( Penicillins
)( Quinolones
)( First generation cephalosporin
)( Second generation cephalosporin
- )(Constipation
)( Augmentin
)( Multivitamins
)( Diphenhydramine
)( Morphine
-
.
)( )(Paracetamol & Actifed
)(
)(
)(
- )(Micromedex
)(
)(
)(
)(
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- )(Viagra
)(
)(
)(
)( )(Nitroglycerin
- )(Viaga
)( Atenolol
)( Paracetamol
)( Amoxicillin
)( Sildenafil
- :
)( Aspirin
)( Bisacodyl
)( Molax
)( Tegretol
- ) (Tetracycline ) (Al+++ & Fe++ :
)(
)(
)(
)(
- ) (Tetracycline
)(
)(
)(
)(
- ) (Insulin
)( Lente insulin
)( NPH insulin
)( Human mixtard 30/70 insulin
)( Regular insulin
- ) (Insulin ) (
)( Regular insulin
)( Insulin Lispro
)( Insulin Aspart
)( Human mixtard 30/70

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-
)(
)(
)(
)(
- ) (UTI :
)( Amoeba
)( Gram positive & negative microorganisms
)( Gram positive microorganisms
)( Gram negative microorganisms
- ) (Macrolides :
)( Clarithromycin
)( Erythromycin
)( Azithromycin
)( Clindamycin
- ) (ACE inhibitors :
)( Captopril
)( Lisonopril
)( Ramipril
)( Nifedipine
- ) (Paracetamol
)( 500 mg every 6 h
)( 500 mg every 8 h
)( 700 mg every 10 h
)( 10 15 mg/Kg every 4 6 h a day
- )(A
)( 500 IU
)( 100 IU
)( 10 IU
)( 50000 IU
- ) (Valproic acid:
)(
)(
)(
)(
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: -
)(
)(
)(
)(
-
Ampicillin ()
Insulin ()
Spironolactone ()
Lidocaine ()
(K-Channel Blockers) -
Captopril ()
Diltiazem ()
Atenolol ()
Sotalol ()
(Paracetamol) -
Aspirin ()
Ampicillin ()
Atenolol ()
N-acetylcysteine ()

Prepared and written


By
Yehia H. Elmelik PhD
Lecturer in Pharmacy Dept
Riyadh

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