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Dissolution Media Delivery Station DosaPrep X8 ™, \ \ ‘be. reliable ..., Conforms to USP guidelines y fast, accurate, reliable Dissolution Media Degasser and Dispenser +s.+.DosaPrep X8 PFOA, GLP/GMP regulations and recommendations The United States Pharmacopeia (USP) recogriaes that dissolved gases in the dissolution medium may elfectcsso- {ution test results and recommends that gases be removed before the testis performed (USP 231NF 18; Uited States FPharmecopeial Convention: Rockvile, MD, 1994; p,1792).< veces USPEBA sseerseee GLP/GMP EP ER re kDA ‘Automated preparation and dispensing of dissolution media DosaPrep XB processes upto 8 iters of dissolution media in one operation in accordance with regulatory require- ments. Media may be mixed fom water and concentrated acid by weight, fitered, warmed, degassed under vacuum and mixed. When complete itis then precisely dispensed in indvidaal volumes up to 8 vessels, The complete sequence is accurately monitored and the value of each dispensed volume is documented on an externa printer or °C ‘Acid mixing For the precise addition of concentrated ‘hydrochloric acid (max, 36%) a second iquidl channel is avaiable, The composi- tion calculation i camied out gravimetr- aly ia @ precision belance, The risk of working with acidic media s held to a minimum. Filtering ‘An easiy exchangeable fier cartridge is located isin within the fil tube. The

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