Dissolution
Media Delivery Station
DosaPrep X8
™,
\
\ ‘be. reliable ..., Conforms to USP guidelines
yfast, accurate, reliable
Dissolution
Media Degasser and Dispenser
+s.+.DosaPrep X8
PFOA, GLP/GMP
regulations and recommendations
The United States Pharmacopeia (USP)
recogriaes that dissolved gases in the
dissolution medium may elfectcsso-
{ution test results and recommends that
gases be removed before the testis
performed (USP 231NF 18; Uited States
FPharmecopeial Convention: Rockvile,
MD, 1994; p,1792).<
veces USPEBA
sseerseee GLP/GMP EP ER
re kDA
‘Automated preparation and
dispensing of dissolution media
DosaPrep XB processes upto 8 iters of
dissolution media in one operation in
accordance with regulatory require-
ments. Media may be mixed fom water
and concentrated acid by weight,
fitered, warmed, degassed under
vacuum and mixed. When complete itis
then precisely dispensed in indvidaal
volumes up to 8 vessels, The complete
sequence is accurately monitored and
the value of each dispensed volume is
documented on an externa printer or
°C
‘Acid mixing
For the precise addition of concentrated
‘hydrochloric acid (max, 36%) a second
iquidl channel is avaiable, The composi-
tion calculation i camied out gravimetr-
aly ia @ precision belance, The risk of
working with acidic media s held to a
minimum.
Filtering
‘An easiy exchangeable fier cartridge is
located isin within the fil tube. The