Malaria life cycle

Malaria
Incubation Period
to 30 days 7 shorter periods

longer ones

P. falciparum
.P. malariae

Uncomplicated Malaria
Cold stage (sensation of cold, shivering)
Hot stage (fever, headaches, vomiting; seizures
, Sweating stage (sweats, return to normal temperature
tiredness

"attacks

occur every second day with the "tertian

P.ovale,P.vivax,P.falciparum

Parasite
:s

.Every third day with the "quartan" parasite , P. malaria

symptoms
Fever
Chills
Sweats
Headaches
Nausea and vomiting
Body aches
General malaise

Physical
findings
Elevated temperature
Perspiration
Weakness
.
Enlarged spleen

Severe Malaria
P. falciparum Cerebral malaria
Severe anemia
Hemoglobinuria
Pulmonary edema or acute respiratory distress syndrome
Abnormalities in blood coagulation and thrombocytopenia
Cardiovascular collapse and shock

Other manifestations
Acute kidney failure
Hyperparasitemia
Metabolic acidosis
Hypoglycemia

Other Manifestations of Malaria

Neurological defects
Recurrent infections with P. falciparum
may result in severe anemia

Malaria during pregnancy

P. Vivax malaria can cause rupture of the spleen

or acute respiratory distress syndrome (ARDS)

Nephrotic syndrome
Hyperreactive malarial splenomegaly

Diagnosis