Traditional vaccines may be attenuated form of the pathogen, that is, live pathogen is weakened through chemical or physical process (e.g. vaccines against measles, mumps, polio); whole pathogen that is completely killed or destroyed chemically (e.g. vaccines against flu, cholera, etc.) BY LABORATORY METHODS DNA MOLECULES FORMED
Advantages of a DNA vaccine include the following:
Plasmids are easily manufactured in large amounts. DNA is stable and it resists temperature extremes so storage and transport are straightforward. The plasmid does not replicate and encodes only proteins of interest.