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ChassidyR.

Folley
SkeletalMuscleSystemLabReport

Introductoryparagraph:
Skeletalmuscleconnectstotheskeleton,toformpartofthemechanicalmovementsystem,
givingtheabilitytomovelimbsthroughouttheentirebody.In1864Kuhnediscoveredthe
myosinproteinandthattheskeletalmuscleismadeupofhundreds,oreventhousands,of
musclefibersbundledtogetherandwrappedinaconnectivetissuecovering.Muscle
contractionsofthosethousandsofmusclefiberswerestudiedbyfourmajorscientists:Andrew
F.Huxley,RolfNiedergerke,HughHuxleyandjeanHansonin1954theyfoundthatATP
causesactinandmyosintoslideacrosseachotherastheskeletalmusclecontractionoccurred.
AngeloMossointhelate1800sworkedwithphysiologistsWilhelmLudwig.DuBoisReymond,
HugoKronecker,andEtienneMareytoconductresearchonmusclefatigueusingmuscle
tracing.
Applyingknowledgeofskeletalmusclestructurecontraction,fatigueandtheoverallstructureof
skeletalmusclesfollowinglabswereconductedshowingtheeffectoftheATPontherabbit
fibersandthefatiguecausedbycontinuousandrepetitivemusclecontractions.

Part1.
SkeletalMuscleStructure:

Figure1.Askeletalmuscleiscomposedofdifferentkindoftissuesandalayerofconnective
tissue.Theepimysiumsurroundstheskeletalmuscleandperimysiumisanotherkindof
connectivetissue.TheFasciaisacoveroverthesurfaceonthemuscle.Theskeletalfibersare
calledfascicles.Theendomysiumisathinlayeroftissue.

Part2.
MuscleContractionLab:

beforecontraction

aftercontraction
MuscleFiber
lengthinmm

beforeATP
length

afterATPlength beforeATP
width

afterATPwidth

16.5cm

14.4cm

.6cm

1cm

15.2cm

12.5cm

.9cm

1cm

15.5cm

12cm

1cm

.7cm

12cm

10.3cm

.7cm

.8cm

Averages

14.8

12.3

0.8

0.875

%contraction

Figure2,3

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